Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(645 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,017 products)
- BACE(37 products)
- Beta Amyloid(228 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(445 products)
- GABA Receptor(372 products)
- Gamma-secretase(61 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
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Found 5487 products of "Neuroscience"
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LP 12 hydrochloride
CAS:LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).Formula:C32H40ClN3OColor and Shape:SolidMolecular weight:518.14AChE-IN-29
AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electricFormula:C18H19BrN2O2Color and Shape:SolidMolecular weight:375.26RuBi-GABA
CAS:Ruthenium-bipyridine-triphenylphosphine caged GABAFormula:C42H39F6N5O2P2RuPurity:98%Color and Shape:SolidMolecular weight:922.8AHN-683
CAS:AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.Formula:C42H32FN3O7Purity:98%Color and Shape:SolidMolecular weight:709.72Multitarget AD inhibitor-1
CAS:Multitarget AD inhibitor-1: reversible, selective BuChE blocker, inhibits β-secretase and amyloid/tau aggregation, promising for Alzheimer's research.Formula:C29H38N2OColor and Shape:SolidMolecular weight:430.636Anabaseine
CAS:Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.Formula:C10H12N2Color and Shape:SolidMolecular weight:160.22LY3027788 hydrochloride
CAS:LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.Formula:C25H32ClF2NO11SColor and Shape:SolidMolecular weight:628.03nAChR modulator-1
CAS:nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .Formula:C12H8ClN3O2Color and Shape:SolidMolecular weight:261.66Syk Inhibitor II hydrochloride
CAS:Syk signaling is key in lupus. Syk inhibitors reduce inflammation and sepsis severity in FcgRIIb-/- mice, lowering cytokines and organ damage.Formula:C14H16ClF3N6OPurity:99.05%Color and Shape:SolidMolecular weight:376.77BChE-IN-10
CAS:BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.Formula:C23H20O5Color and Shape:SolidMolecular weight:376.4MGS0274
CAS:MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.Formula:C21H32FNO7Color and Shape:SolidMolecular weight:429.485MAO-B-IN-20
MAO-B-IN-20, potent with 0.037 μM IC50, is stable and BBB permeable, useful for Parkinson's research.Formula:C20H18F2N2O2Color and Shape:SolidMolecular weight:356.37Echimidine N-oxide
CAS:Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.Formula:C20H31NO8Color and Shape:SolidMolecular weight:413.47JNJ-67569762
CAS:JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).Formula:C22H22F4N4O5SColor and Shape:SolidMolecular weight:530.49Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Formula:C12H10ClN2NaO5SPurity:99.52% - >99.99%Color and Shape:SolidMolecular weight:352.73AChE/BChE-IN-11
CAS:AChE/BChE-IN-11, natural from artichoke leaves, inhibits AChE and BChE (IC50: 70/71 μM) for Alzheimer's research.Formula:C21H22O12Color and Shape:SolidMolecular weight:466.39SC-53116
CAS:SC-53116 HCl can increase the production of serotonin in central nervous system tissues and is a psychoactive agent.Formula:C16H22ClN3O2Color and Shape:SolidMolecular weight:323.82β-Amyloid (18-28)
CAS:Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.Formula:C55H81N13O18Purity:98%Color and Shape:SolidMolecular weight:1212.318-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Formula:C5H6N6Purity:99.82%Color and Shape:SolidMolecular weight:150.14β-Amyloid (12-28)
CAS:Amyloid β-peptide fragment; minimum section required to bind to brain proteins.Formula:C89H135N25O25Purity:98%Color and Shape:SolidMolecular weight:1955.18α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Formula:C21H20FN3O4Color and Shape:SolidMolecular weight:397.4Dual AChE-MAO B-IN-3
Compound C10 is a potent dual AChE/MAO-B inhibitor with IC50s of 0.58μM (AChE) and 0.41μM (MAO-B), useful in Alzheimer's research.Formula:C30H26F3NO3Color and Shape:SolidMolecular weight:505.53Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurity:99.63% - 99.96%Color and Shape:SolidMolecular weight:390.4Ref: TM-T9694
1mg120.00€2mg170.00€5mg289.00€10mg467.00€25mg835.00€50mg1,134.00€100mg1,504.00€1mL*10mM (DMSO)319.00€Dicloromezotiaz
CAS:Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.Formula:C19H12Cl3N3O2SColor and Shape:SolidMolecular weight:452.74CALP2
CAS:CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.Formula:C68H104N14O13SPurity:98%Color and Shape:SolidMolecular weight:1357.72Guvacine hydrobromide
CAS:Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.Formula:C6H10BrNO2Purity:98%Color and Shape:SolidMolecular weight:208.05γ-Secretase Modulators
CAS:gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Formula:C26H24F3N3O3Purity:98%Color and Shape:SolidMolecular weight:483.48BChE-IN-12
CAS:BChE-IN-12, non-competitive BChE inhibitor from Bletilla striata, IC50=2.3μM; potential Alzheimer’s research.Formula:C31H30O5Color and Shape:SolidMolecular weight:482.57β-Amyloid (1-11)
CAS:Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFormula:C56H76N16O22Purity:98%Color and Shape:SolidMolecular weight:1325.3Guanylyl Imidodiphosphate (lithium salt)
CAS:Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.Formula:C10H13Li4N6O13P3Color and Shape:SolidMolecular weight:545.93SB-408124
CAS:SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.Formula:C19H18F2N4OPurity:99.81%Color and Shape:SolidMolecular weight:356.37mGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Formula:C18H19ClFN3O2Color and Shape:SolidMolecular weight:363.82nAChR agonist 2
CAS:Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,Formula:C11H16N2Color and Shape:SolidMolecular weight:176.263sabcomeline
CAS:Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.Formula:C10H15N3OColor and Shape:SolidMolecular weight:193.25β-Amyloid (1-28)
CAS:β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.Formula:C145H209N41O46Purity:98%Color and Shape:SolidMolecular weight:3262.51α-Conotoxin PIA TFA
α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.Formula:C81H126F3N27O27S4Purity:98.81%Color and Shape:SolidMolecular weight:2095.3Zanapezil free base
CAS:Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.Formula:C25H32N2OColor and Shape:SolidMolecular weight:376.5445β-Cholanic acid
CAS:5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.
Formula:C24H40O2Purity:98.91% - 99.89%Color and Shape:SoildMolecular weight:360.57Peptide 401
CAS:Peptide 401: AMP from bee/wasp venom, triggers histamine release, reduces paw swelling.Formula:C110H192N40O24S4Purity:98%Color and Shape:SolidMolecular weight:2587.222,3-Dehydrosilybin A
CAS:2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.Formula:C25H20O10Color and Shape:SolidMolecular weight:480.43MmTx1 toxin
Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].Formula:C295H455N95O97S10Purity:98%Color and Shape:SolidMolecular weight:7205Millmerranone A
Millmerranone A shows the acetylcholinesterase inhibitory property.Formula:C27H28O9Color and Shape:SolidMolecular weight:496.51Paecilomide
CAS:Paecilomide is a pyridone alkaloid and acetylcholinesterase inhibitor [1] .Formula:C12H15NO4Color and Shape:SolidMolecular weight:237.25BuChE-IN-8
BuChE-IN-8 (compound 19c), a butyrylcholinesterase (BuChE) inhibitor, exhibits an IC50 value of 559 nM and concurrently inhibits human β-secretase (BACE1) andFormula:C28H33ClN4O2SColor and Shape:SolidMolecular weight:525.11(S,S)-BMS-984923
CAS:(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.Formula:C22H15ClN2O2Color and Shape:SolidMolecular weight:374.82Cloxacepride
CAS:cloxacepride is a CaM antagonist that is used to treat asthma disease.Formula:C22H27Cl2N3O4Purity:99.76%Color and Shape:SolidMolecular weight:468.37Cytidine 5′-diphosphoethanolamine
CAS:Cytidine 5′-diphosphoethanolamine, a key intermediate in phosphatidylethanolamine synthesis, also serves as a stimulant of Ach synthesis [1].
Formula:C11H20N4O11P2Color and Shape:SolidMolecular weight:446.24Isograndifoliol
CAS:Isograndifoliol: BChE inhibitor (IC50=0.9μM), weaker AChE inhibitor (IC50=342.9μM), with vasorelaxant and anti-tumor properties.Formula:C19H26O3Color and Shape:SolidMolecular weight:302.41Arisugacin G
CAS:Arisugacin G, a microbial metabolite, is a structural analogue of Arisugacin A. Unlike its analogue, Arisugacin G does not exhibit activity against AChE (acetylcholinesterase).Formula:C27H32O5Color and Shape:SolidMolecular weight:436.54Pellotine
CAS:Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.Formula:C13H19NO3Color and Shape:SolidMolecular weight:237.295
