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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Lenacapavir

    CAS:
    <p>Lenacapavir (GS-6207) is the first HIV-1 capsid inhibitor approved by the U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada for the treatment of MDR HIV-1 infection.Cost-effective and quality-assured.</p>
    Formula:C39H32ClF10N7O5S2
    Purity:99.61% - 99.87%
    Color and Shape:Solid
    Molecular weight:968.28
  • Etarotene

    CAS:
    <p>Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a</p>
    Formula:C25H32O2S
    Purity:99.58% - 99.93%
    Color and Shape:Solid
    Molecular weight:396.59
  • BDCRB


    <p>BDCRB disrupts HCMV DNA maturation by altering terminase cleavage, extending packaging 30 kb until second site.</p>
    Formula:C12H11BrCl2N2O4
    Purity:99.41% - 99.43%
    Color and Shape:Soild
    Molecular weight:398.04
  • BILB-1941

    CAS:
    <p>BILB-1941 (BILB-1941ZW) is an inhibitor of HCV NS5B polymerase and can be used in studies about HCV infection.</p>
    Formula:C34H34N4O4
    Purity:99.51% - 99.65%
    Color and Shape:Solid
    Molecular weight:562.66
  • 2'-C-Methyladenosine

    CAS:
    <p>2'-C-Methyladenosine from C. renalis inhibits HCV, NS5B RNA synthesis (IC50: 0.3, 1.9µM), and LRV1 in L. guyanensis, L. braziliensis.</p>
    Formula:C11H15N5O4
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:281.27
  • CPA inhibitor

    CAS:
    <p>CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.</p>
    Formula:C18H19NO4
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:313.35
  • Cathepsin X-IN-1

    CAS:
    <p>Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].</p>
    Formula:C15H13N3O3S
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:315.35
  • P32/98 hemifumarate

    CAS:
    <p>P32/98 hemifumarate is a DPP4 inhibitor with hypoglycemic properties and is used in the study of type 2 diabetes.</p>
    Formula:C22H40N4O6S2
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:520.71
  • Atevirdine

    CAS:
    <p>Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).</p>
    Formula:C21H25N5O2
    Purity:98.20%
    Color and Shape:Solid
    Molecular weight:379.46
  • DB04760

    CAS:
    <p>DB04760: selective MMP-13 inhibitor, non-zinc-chelating, IC50=8nM, reduces paclitaxel neurotoxicity, anticancer.</p>
    Formula:C22H20F2N4O2
    Purity:99.93% - 99.99%
    Color and Shape:Solid
    Molecular weight:410.42
  • JNJ-10311795

    CAS:
    <p>JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.</p>
    Formula:C40H35N2O6P
    Purity:97.43%
    Color and Shape:Solid
    Molecular weight:670.69
  • TG-2-IN-1

    CAS:
    <p>TG-2-IN-1 (Compound D003) is a transglutaminase-2 ( TGM-2 ) inhibitor. TG-2-IN-1 can be used in myopia research[1].</p>
    Formula:C8H13ClN2OS
    Purity:98.43%
    Color and Shape:Solid
    Molecular weight:220.72
  • CP-544439

    CAS:
    <p>CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.</p>
    Formula:C18H19FN2O6S
    Purity:95.02% - 98.66%
    Color and Shape:Solid
    Molecular weight:410.42
  • Setrobuvir

    CAS:
    <p>Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with</p>
    Formula:C25H25FN4O6S2
    Purity:98.92% - >99.99%
    Color and Shape:Solid
    Molecular weight:560.62
  • Granotapide

    CAS:
    <p>Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic</p>
    Formula:C39H37F3N2O8
    Purity:99.70% - 99.79%
    Color and Shape:Solid
    Molecular weight:718.71
  • PG-116800

    CAS:
    <p>PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.</p>
    Formula:C24H27N3O7S
    Purity:98.03% - 99.66%
    Color and Shape:Solid
    Molecular weight:501.55
  • Sovaprevir

    CAS:
    <p>Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.</p>
    Formula:C43H53N5O8S
    Purity:99.11%
    Color and Shape:Solid
    Molecular weight:799.97
  • Melagatran

    CAS:
    <p>Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.</p>
    Formula:C22H31N5O4
    Purity:98.29% - >99.99%
    Color and Shape:Solid
    Molecular weight:429.51
  • Opaviraline

    CAS:
    <p>Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.</p>
    Formula:C14H17FN2O3
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:280.29
  • MMP2-IN-3

    CAS:
    <p>MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM).</p>
    Formula:C23H21N3O
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:355.43
  • Uprifosbuvir

    CAS:
    <p>Uprifosbuvir is an inhibitor of uridine nucleotide analog HCV NS5B polymerase.</p>
    Formula:C22H29ClN3O9P
    Purity:99.73% - >99.99%
    Color and Shape:Solid
    Molecular weight:545.91
  • Sirpiglenastat

    CAS:
    <p>Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.</p>
    Formula:C22H27N5O5
    Purity:98.01% - 98.37%
    Color and Shape:Solid
    Molecular weight:441.48
  • Emivirine

    CAS:
    <p>Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.</p>
    Formula:C17H22N2O3
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:302.37
  • Tyrosinase-IN-2

    CAS:
    <p>Tyrosinase-IN-2, a potent tyrosinase inhibitor, may help in skin lightening and food preservation research.</p>
    Formula:C8H8N4O2S
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:224.24
  • Isatoribine

    CAS:
    <p>Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection.</p>
    Formula:C10H12N4O6S
    Purity:98.99% - 99.75%
    Color and Shape:Solid
    Molecular weight:316.29
  • AGPS-IN-2i

    CAS:
    <p>AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.</p>
    Formula:C18H17F2N3O2
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:345.34
  • HIV-1 integrase inhibitor 8

    CAS:
    <p>HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].</p>
    Formula:C21H24O2
    Purity:98.91%
    Color and Shape:Solid
    Molecular weight:308.41
  • TS-021

    CAS:
    <p>TS-021 is a selective dipeptidyl peptidase 4 (DPP-4) inhibitor with antidiabetic activity for the study of type 2 diabetes.</p>
    Formula:C17H24FN3O5S
    Purity:>99.99% - >99.99%
    Color and Shape:Solid
    Molecular weight:401.45
  • MMP-2/MMP-9 Inhibitor I

    CAS:
    <p>MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.</p>
    Formula:C21H19NO4S
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:381.44
  • KM-023

    CAS:
    <p>KM-023 is a new second-generation non-nucleoside reverse transcriptase inhibitor for the study of human immunodeficiency virus (HIV) type 1 infection.</p>
    Formula:C18H19N3O3
    Purity:99.47% - >99.99%
    Color and Shape:Solid
    Molecular weight:325.36
  • L 756423

    CAS:
    <p>L756423 is a potent, selective HIV protease inhibitor (Ki=0.049 nM), effective against HIV spread in MT25 lymphocytes at 0.1-0.5 nM, useful for AIDS research.</p>
    Formula:C39H48N4O5
    Purity:99.34% - 99.88%
    Color and Shape:Solid
    Molecular weight:652.82
  • 20S Proteasome activator 1

    CAS:
    <p>20S Proteasome activator 1: IC50—0.3 μM (trypsin), 0.7 μM (chymotrypsin), 1.8 μM (caspase); reduces alpha-synuclein A53T, aids neurodegenerative studies.</p>
    Formula:C27H19ClF2N2OS
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:492.97
  • Gemigliptin

    CAS:
    <p>Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)</p>
    Formula:C18H19F8N5O2
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:489.36
  • MK-8325

    CAS:
    <p>MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailability</p>
    Formula:C43H54Cl2F2N8O6Si
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:915.93
  • Thrombin inhibitor 1

    CAS:
    <p>Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).</p>
    Formula:C22H20Cl2F2N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:497.32
  • GS-6620

    CAS:
    <p>GS-6620 is a HCV nonstructural protein 5B (NS5B) inhibitor.</p>
    Formula:C29H37N6O9P
    Color and Shape:Solid
    Molecular weight:644.61
  • SSR 69071

    CAS:
    <p>SSR69071: selective neutrophil elastase inhibitor, stronger for humans (Ki=0.0168 nM), may treat COPD, asthma, and reduce heart injury.</p>
    Formula:C27H32N4O7S
    Color and Shape:Solid
    Molecular weight:556.63
  • NS5A-IN-2

    CAS:
    <p>NS5A-IN-2, a potent inhibitor, is highly effective against HCV 1b and shows increased activity for GT 3a with good metabolic stability.</p>
    Formula:C46H45N7O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:807.89
  • XL-784

    CAS:
    <p>XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.</p>
    Formula:C42H42Cl2F4MgN6O16S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1122.15
  • Ravidasvir HCl

    CAS:
    <p>Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.</p>
    Formula:C42H52Cl2N8O6
    Color and Shape:Solid
    Molecular weight:835.828
  • Inogatran

    CAS:
    <p>Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.</p>
    Formula:C21H38N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.56
  • Paltimatrectinib

    CAS:
    <p>Paltimatrectinib (PBI-200) is a tyrosine kinase inhibitor with anticancer activity, and is used in the study of bladder, breast, and colorectal cancers.</p>
    Formula:C20H15F5N6
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:434.37
  • ABP 25

    CAS:
    <p>ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.</p>
    Formula:C55H66ClN5O3
    Color and Shape:Solid
    Molecular weight:880.6
  • Beclabuvir HCl

    CAS:
    <p>Beclabuvir (BMS-791325) is an HCV inhibitor targeting NS5B polymerase with sub-28 nM potency for genotypes 1, 3, 4, 5.</p>
    Formula:C36H46ClN5O5S
    Color and Shape:Solid
    Molecular weight:696.3
  • BAY-678

    CAS:
    <p>BAY-678: Oral selective human neutrophil elastase inhibitor; IC50: 20 nM; SGC-approved chemical probe.</p>
    Formula:C20H15F3N4O2
    Purity:97.89%
    Color and Shape:Solid
    Molecular weight:400.35
  • Proteasome-IN-5

    CAS:
    <p>Proteasome-IN-5, also known as compound 5, acts as a proteasome inhibitor [1].</p>
    Formula:C20H30BN5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:463.29
  • Collagen proline hydroxylase inhibitor

    CAS:
    <p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>
    Formula:C18H18N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:354.36
  • Ro 31-9790

    CAS:
    <p>Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).</p>
    Formula:C15H29N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:315.41
  • ONO 4817

    CAS:
    <p>ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.</p>
    Formula:C22H28N2O6
    Color and Shape:Solid
    Molecular weight:416.47
  • MMP-7-IN-3

    CAS:
    <p>MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.</p>
    Formula:C34H43ClF3N7O9S
    Purity:99.915%
    Color and Shape:Solid
    Molecular weight:818.26
  • KB-R7785

    CAS:
    <p>KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.</p>
    Formula:C18H27N3O4
    Color and Shape:Solid
    Molecular weight:349.42
  • Cipemastat

    CAS:
    <p>Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).</p>
    Formula:C22H36N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:436.55
  • Azt-pmap

    CAS:
    <p>AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].</p>
    Formula:C20H25N6O8P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:508.42
  • XL-784 free base

    CAS:
    <p>XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).</p>
    Formula:C21H22ClF2N3O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:549.93
  • MDL 27324

    CAS:
    <p>MDL 27324 is an inhibitor of human neutrophil elastase.</p>
    Formula:C29H38F3N5O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:641.7
  • AA74-1

    CAS:
    <p>AA74-1 is a potent, selective APEH inhibitor that significantly enhances T-cell proliferation by inhibiting APEH activity [1].</p>
    Formula:C16H28N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:308.42
  • Ro 32-7315

    CAS:
    <p>Ro 32-7315 is a selective inhibitor of ADAM17.</p>
    Formula:C22H35N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:453.6
  • MK-3281

    CAS:
    <p>MK-3281: Oral, potent HCV NS5B inhibitor with promising properties and efficacy in replication trials, suitable for clinical use.</p>
    Formula:C29H37N3O3
    Color and Shape:Solid
    Molecular weight:475.62
  • MDL 101146

    CAS:
    <p>MDL 101146 is an orally active neutrophil elastase inhibitor.</p>
    Formula:C29H37F5N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:632.62
  • JW 480

    CAS:
    <p>JW480 is a potent and selective inhibitor of KIAA1363, a serine hydrolase enzyme.</p>
    Formula:C22H23NO2
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:333.42
  • MMP-7-IN-2

    CAS:
    <p>MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.</p>
    Formula:C28H40ClF3N6O9S
    Purity:97.82%
    Color and Shape:Solid
    Molecular weight:729.17
  • Proteasome β2c/i-IN-1

    CAS:
    <p>Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1].</p>
    Formula:C32H48N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:600.75
  • ND-378

    CAS:
    <p>ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.</p>
    Formula:C18H19NO4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:377.48
  • AZD-7295

    CAS:
    <p>AZD-7295 (A-689) is an NS5A inhibitor that may be used to treat HCV infection.</p>
    Formula:C32H35F3N4O5S
    Color and Shape:Solid
    Molecular weight:644.7
  • PTC725

    CAS:
    <p>PTC725 is a selective HCV 1b replicons inhibitor. It has been shown to target the nonstructural protein 4B.</p>
    Formula:C23H18F4N6O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:518.49
  • EP1013

    CAS:
    <p>EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.</p>
    Formula:C18H23FN2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:382.38
  • HIV-1 protease-IN-12

    CAS:
    <p>HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-</p>
    Formula:C25H35N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:489.63
  • GSK-2485852

    CAS:
    <p>GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.</p>
    Formula:C27H25BF2N2O6S
    Color and Shape:Solid
    Molecular weight:554.37
  • MMP13-IN-3

    CAS:
    <p>MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, &gt;1000x selective, for osteoarthritis treatment.</p>
    Formula:C24H22N4O5
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:446.46
  • TP0556351

    CAS:
    <p>TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.</p>
    Formula:C50H70N10O16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1067.15
  • Apratastat

    CAS:
    <p>Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)</p>
    Formula:C17H22N2O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:414.5
  • MDL-101146, (R)-

    CAS:
    <p>MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.</p>
    Formula:C29H37F5N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:632.62
  • LU-002i

    CAS:
    <p>LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].</p>
    Formula:C35H52N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:640.81
  • Phe-Pro-Ala-pNA

    CAS:
    <p>Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.</p>
    Formula:C23H27N5O5
    Color and Shape:Solid
    Molecular weight:453.49
  • Flovagatran sodium

    CAS:
    <p>Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.</p>
    Formula:C27H36BN3NaO7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:548.4
  • Z-FG-NHO-BzOME

    CAS:
    <p>Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,</p>
    Formula:C27H27N3O7
    Color and Shape:Solid
    Molecular weight:505.52
  • HIV-1 protease-IN-7

    CAS:
    <p>HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].</p>
    Formula:C68H104N10O12S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1285.68
  • BAY-320

    CAS:
    <p>BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.</p>
    Formula:C26H26F2N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:492.52
  • Cyclotheonellazole A

    CAS:
    <p>Cyclotheonellazole A inhibits elastase (IC50=0.034nM) &amp; chymotrypsin (IC50=0.62nM), a natural macrocyclic peptide.</p>
    Formula:C44H54N9NaO14S2
    Color and Shape:Solid
    Molecular weight:1020.07
  • JTK-853

    CAS:
    <p>JTK-853: novel non-nucleoside HCV polymerase inhibitor with strong antiviral activity (EC50: 0.38 μM genotype 1a, 0.035 μM 1b).</p>
    Formula:C28H23F7N6O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:704.64
  • Z-PDLDA-NHOH

    CAS:
    <p>Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].</p>
    Formula:C22H32N4O6
    Color and Shape:Solid
    Molecular weight:448.51
  • HIV-1 protease-IN-9

    CAS:
    <p>HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and a</p>
    Formula:C37H41N7O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:679.83
  • DCLK1-IN-2

    CAS:
    <p>DCLK1-IN-2 (Compound I-5) is a potent inhibitor of DCLK1, exhibiting an IC50 of 171.3 nM, and demonstrates significant antiproliferative effects on SW1990 cell</p>
    Formula:C26H32N8O3S
    Color and Shape:Solid
    Molecular weight:536.65
  • Berotralstat HCl

    CAS:
    <p>Berotralstat HCl is a selective plasma kallikrein inhibitor, reducing pain and swelling in HAE by blocking bradykinin release.</p>
    Formula:C30H28Cl2F4N6O
    Color and Shape:Solid
    Molecular weight:635.4886
  • Z-DEVD-CMK

    CAS:
    <p>Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].</p>
    Formula:C27H35ClN4O12
    Color and Shape:Solid
    Molecular weight:643.04
  • I-XW-053

    CAS:
    <p>I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-</p>
    Formula:C22H16N2O2
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:340.37
  • O-Benzoylhydroxylamine

    CAS:
    <p>O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].</p>
    Formula:C7H7NO2
    Color and Shape:Solid
    Molecular weight:137.14
  • Kallikrein-IN-2

    CAS:
    <p>Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.</p>
    Formula:C28H25F3N4O4
    Color and Shape:Solid
    Molecular weight:538.52
  • Neurodegenerative Disorder-Targeting Compound 1

    CAS:
    <p>Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].</p>
    Formula:C28H28N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:484.55
  • NCI-B16

    CAS:
    <p>NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].</p>
    Formula:C27H26N8O4
    Color and Shape:Solid
    Molecular weight:526.55
  • KCC009

    CAS:
    <p>KCC009 is a potent and selective Transglutaminase 2 Inhibitor.</p>
    Formula:C21H22BrN3O5
    Color and Shape:Solid
    Molecular weight:476.32
  • SQ 32056

    CAS:
    <p>SQ 32056 is a cathepsin E inhibitor.</p>
    Formula:C37H56N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:636.86
  • BMS-189664 HCl

    CAS:
    <p>BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.</p>
    Formula:C22H35ClN6O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:515.07
  • Ecallantide

    CAS:
    <p>Ecallantide (DX-88) is a recombinant inhibitor specifically targeting plasma kallikrein, which serves to impede the synthesis of bradykinin.</p>
    Formula:C305H448N88O91S8
    Color and Shape:Solid
    Molecular weight:7059.88
  • Proteasome-IN-4


    <p>Proteasome-IN-4, a potent non-covalent inhibitor (IC50=8.39nM), halts cancer cell growth, useful for oncology studies.</p>
    Formula:C44H58N6O5
    Color and Shape:Solid
    Molecular weight:750.97
  • MMP-145

    CAS:
    <p>MMP-145 is used as a protease inhibitor.</p>
    Formula:C20H20N2O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:432.45
  • HIV-1 protease-IN-8

    CAS:
    <p>HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.</p>
    Formula:C25H35N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:489.63
  • Human enteropeptidase-IN-1

    CAS:
    <p>Enteropeptidase-IN-1: orally active, potent inhibitor, low systemic exposure, for anti-obesity research.</p>
    Formula:C20H18N4O7
    Color and Shape:Solid
    Molecular weight:426.38
  • MeOSuc-AAPV-CMK

    CAS:
    <p>MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated</p>
    Formula:C22H35ClN4O7
    Color and Shape:Solid
    Molecular weight:502.99
  • NK3201

    CAS:
    <p>NK3201, a specific chymase inhibitor, suppresses bleomycin-induced pulmonary fibrosis in hamsters.</p>
    Formula:C31H29N5O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:567.59
  • (1R,4S)-Yimitasvir diphosphate

    CAS:
    <p>Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A).</p>
    Formula:C49H64N8O14P2
    Color and Shape:Solid
    Molecular weight:1051.03
  • Tyropeptin A-4

    CAS:
    <p>Tyropeptin A-4 is used as a proteasome inhibitor.</p>
    Formula:C31H41N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:551.67
  • BMS-189664

    CAS:
    <p>BMS-189664 is an inhibitor of thrombin.</p>
    Formula:C22H34N6O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:478.61
  • HCV-IN-44

    CAS:
    <p>HCV-IN-44 (compound 28) is an inhibitor of the HCV NS5B protein, efficacious in suppressing HCV virus replication and useful for researching HCV infection [1].</p>
    Formula:C24H26FN3O5S
    Color and Shape:Solid
    Molecular weight:487.54
  • HCV-IN-43

    CAS:
    <p>HCV-IN-43 (compound 2), an HCV NS5B protein inhibitor, efficiently inhibits HCV virus replication and is utilized in the study of HCV infection [1].</p>
    Formula:C26H26FN3O5S
    Color and Shape:Solid
    Molecular weight:511.57
  • Reverse transcriptase-IN-1

    CAS:
    <p>Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7</p>
    Formula:C25H17N7O2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:447.45
  • Cathepsin K inhibitor 3

    CAS:
    <p>Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.</p>
    Formula:C30H31FN4O4S
    Color and Shape:Solid
    Molecular weight:562.65
  • Mergetpa

    CAS:
    <p>Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].</p>
    Formula:C7H15N3O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:237.34
  • Cathepsin Inhibitor 2

    CAS:
    <p>Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: &lt;20 nM).</p>
    Formula:C19H21F6N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.38
  • LY52

    CAS:
    <p>LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.</p>
    Formula:C22H24N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:440.45
  • Atecegatran metoxil

    CAS:
    <p>Atecegatran Metoxil (AZD0837), an oral thrombin inhibitor in development for stroke prevention in atrial fibrillation, is well-tolerated with favorable PK.</p>
    Formula:C22H23ClF2N4O5
    Color and Shape:Solid
    Molecular weight:496.89
  • HIV-1 protease-IN-11

    CAS:
    <p>HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacy</p>
    Formula:C26H37N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:503.65
  • MMP-3 Inhibitor VIII

    CAS:
    <p>Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a critical enzyme involved in tissue remodeling and repair through its role in degrading extracellular matrix proteins, facilitating cell migration. This enzyme has been implicated in various physiological processes including vascular remodeling associated with aneurysm formation, wound healing, the progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII, a cell-permeable sulfonamide-based hydroxamic acid, effectively inhibits MMP-3 by binding to its active site (Ki = 23 nM), thus blocking its enzymatic activity. Additionally, this inhibitor has been demonstrated to suppress the activity of mouse macrophage metalloelastase MME/MMP-12, with an IC50 value of 13 nM, highlighting its potential utility in research on tissue remodeling and disease processes involving MMPs.</p>
    Formula:C20H26N2O5S
    Color and Shape:Solid
    Molecular weight:406.5
  • Dim16

    CAS:
    <p>Dim16, a dual inhibitor of PCSK9/HMG-CoAR, demonstrates potent activity with an IC50 of 19 nM against PCSK9 and significantly impedes PCSK9-LDLR interaction</p>
    Formula:C29H38IN5
    Color and Shape:Solid
    Molecular weight:583.55
  • DS-1040 Tosylate

    CAS:
    <p>DS-1040 Tosylate is a thrombin-activated fibrinolysis inhibitor (TAFI) inhibitor and a fibrinolysis enhancer, used for researching thromboembolic diseases.</p>
    Formula:C23H35N3O5S
    Color and Shape:Solid
    Molecular weight:465.61
  • M867

    CAS:
    <p>M867 is a selective, reversible caspase-3 inhibitor, possessing an IC50 of 1.4 nM and a Ki value of 0.7 nM, demonstrating anti-apoptotic activity [1].</p>
    Formula:C27H43N7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:561.67
  • LM-030

    CAS:
    <p>LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).</p>
    Formula:C46H72N8O12
    Color and Shape:Solid
    Molecular weight:929.11
  • MMP-9 Inhibitor I

    CAS:
    <p>MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively).</p>
    Formula:C27H33N3O5S
    Color and Shape:Solid
    Molecular weight:511.63
  • M190S

    CAS:
    <p>M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.</p>
    Formula:C21H21N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:375.42
  • NS5A-IN-3

    CAS:
    <p>NS5A-IN-3 is a potent NS5A inhibitor with high efficacy against HCV 1b, good activity on 3a, and strong metabolic stability; superior to daclatasvir.</p>
    Formula:C44H44N6O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:784.86
  • PNU-103017

    CAS:
    <p>PNU-103017 is an inhibitor of HIV protease.</p>
    Formula:C28H28N2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:504.6
  • L-689502

    CAS:
    <p>L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM).</p>
    Formula:C39H51N3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:673.84
  • GSK-625433

    CAS:
    <p>GSK-625433: Homochiral inhibitor blocks HCV genotypes 1a/1b polymerase.</p>
    Formula:C26H32N4O5S
    Color and Shape:Solid
    Molecular weight:512.62
  • Petesicatib

    CAS:
    <p>Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.</p>
    Formula:C25H23F6N5O4S
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:603.54
  • SID 26681509

    CAS:
    <p>SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).</p>
    Formula:C27H33N5O5S
    Purity:98.16%
    Color and Shape:Solid
    Molecular weight:539.65
  • MMP3 inhibitor 1

    CAS:
    <p>MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).</p>
    Formula:C23H31N3O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:477.57
  • FK706

    CAS:
    <p>FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.</p>
    Formula:C26H33F3N4NaO7
    Color and Shape:Solid
    Molecular weight:593.556
  • PDDC inhibitor

    CAS:
    <p>PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) is an nSMase2 inhibitor.</p>
    Formula:C27H29N5O4
    Purity:96.09% - 99.39%
    Color and Shape:Solid
    Molecular weight:487.55
  • Filibuvir

    CAS:
    <p>Filibuvir (PF-00868554) inhibits HCV polymerase genotypes 1a/1b, EC50s 59 nM.</p>
    Formula:C29H37N5O3
    Purity:99.28% - >99.99%
    Color and Shape:Solid
    Molecular weight:503.64
  • Ac-YVAD-AOM

    CAS:
    <p>Ac-YVAD-AOM is a selective and potent caspase-1 inhibitor showing antitumor activity and potential analgesic activity.</p>
    Formula:C33H42N4O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:654.71
  • Collagen proline hydroxylase inhibitor-1

    CAS:
    <p>Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。</p>
    Formula:C24H21N5O4
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:443.45
  • ZED-1227

    CAS:
    <p>ZED-1227 (TAK-227) is a TG2 inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac Diseas</p>
    Formula:C26H36N6O6
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:528.6
  • γ-Glu-Tyr

    CAS:
    <p>gamma-Glu-Tyr (gamma-Glutamyltyrosine) is a kokumi peptide against dipeptidyl peptidase-IV (DPP-IV) and is used in the study of diabetes mellitus.</p>
    Formula:C14H18N2O6
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:310.3
  • HIV-1 inhibitor-54

    CAS:
    <p>HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.</p>
    Formula:C27H30N6O4S
    Purity:98.05% - 99.44%
    Color and Shape:Soild
    Molecular weight:534.63
  • Aderamastat

    CAS:
    <p>Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.</p>
    Formula:C21H18N2O4S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:394.44
  • Nesbuvir

    CAS:
    <p>Nesbuvir: HCV NS5B polymerase inhibitor, IC50 9 nM against HCV 1b replicon in liver cancer cells.</p>
    Formula:C22H23FN2O5S
    Purity:99.99%
    Color and Shape:Solid
    Molecular weight:446.49
  • BMS-212122

    CAS:
    <p>BMS-212122 inhibits MTP, reduces lipids and plaque in animal tests.</p>
    Formula:C43H36F6N4O2
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:754.76
  • MK-0674

    CAS:
    <p>MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.</p>
    Formula:C26H27F6N3O2
    Purity:97.3% - 99.91%
    Color and Shape:Solid
    Molecular weight:527.5
  • VBY-825

    CAS:
    <p>VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.</p>
    Formula:C23H29F4N3O5S
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:535.55
  • HCV NS5B polymerase-IN-2

    CAS:
    <p>HCVNS5B polymerase-IN-2 (Compound 298) is an inhibitor of the Ns5b polymerase. It holds potential for research into the treatment of hepatitis C virus (HCV) infections.</p>
    Formula:C26H24N2O4
    Color and Shape:Solid
    Molecular weight:428.48
  • (2R,3S)-Emricasan

    CAS:
    <p>(2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan. This compound acts as an orally effective irreversible pan-caspase inhibitor. (2R,3S)-Emricasan inhibits the increase in caspase-3 activity induced by Zika virus (ZIKV) and protects human cortical neural progenitor cells.</p>
    Formula:C26H27F4N3O7
    Color and Shape:Solid
    Molecular weight:569.5
  • Beclabuvir

    CAS:
    <p>Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 &lt;28 nM.</p>
    Formula:C36H45N5O5S
    Purity:99.87% - 99.93%
    Color and Shape:Solid
    Molecular weight:659.84
  • Immunoproteasome activator 1

    CAS:
    <p>Immunoproteasome Activator 1 (compound A) is a selective immunoproteasome activator that enhances the presentation of individual MHC-I binding peptides by over 100 times. It binds to the proteasomal structural subunit PSMA1 and facilitates the association of the proteasome activators PA28α/β (PSME1/PSME2) with the immunoproteasome.</p>
    Formula:C24H23N3O3
    Color and Shape:Solid
    Molecular weight:401.46
  • UK-370106

    CAS:
    <p>UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-</p>
    Formula:C35H44N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:572.73
  • Isobutylamido thiazolyl resorcinol

    CAS:
    <p>Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.</p>
    Formula:C13H14N2O3S
    Color and Shape:Solid
    Molecular weight:278.33
  • LK-732

    CAS:
    <p>LK-732 is a thrombin inhibitor with antithrombotic activity. It exhibits dose-dependent inhibition in models of hypercoagulability, with an IC50 value of 1.3 mg/kg. LK-732 is used in cardiovascular and cerebrovascular research.</p>
    Formula:C25H29N5O3S
    Color and Shape:Solid
    Molecular weight:479.59
  • Boc3Arg


    <p>Boc 3 Arg is a tert-butyl carbamate-protected arginine compound. It serves as an efficient tag that induces degradation by directly targeting proteins to the 20S proteasome.</p>
    Formula:C21H39N5O7
    Color and Shape:Solid
    Molecular weight:473.56
  • 3-Aminobenzene-1,2-diol

    CAS:
    <p>3-Aminobenzene-1,2-diol (compound C8) is an inhibitor of matrix metalloproteinases (MMP), with IC50 values of 20, 26, 16, and 16.3 μM against MMP-2, MMP-8, MMP-9, and MMP-14, respectively.</p>
    Formula:C6H7NO2
    Color and Shape:Solid
    Molecular weight:125.13
  • TGase2-IN-1

    CAS:
    <p>TGase2-IN-1 (Compound 22) is an orally effective TGase2 inhibitor with an IC50 of 1.12 µM. It inhibits TGase2 in human retinal microvascular endothelial cells with a strikingly lower IC50 of 0.07 µM. The oral bioavailability of TGase2-IN-1 is 74.6%. Additionally, it can suppress retinal vascular leakage in a mouse model of diabetes induced by Streptozotocin.</p>
    Formula:C23H25N3O3
    Color and Shape:Solid
    Molecular weight:391.46
  • Tyrosinase-IN-39


    <p>Tyrosinase-IN-39 (compound 5r) is a competitive inhibitor of tyrosinase, with an IC50 of 6.4 μM, and is used in the study of skin diseases.</p>
    Formula:C23H19N5O4S2
    Color and Shape:Solid
    Molecular weight:493.56
  • SCO-792


    <p>SCO-792: potent, reversible oral enteropeptidase inhibitor, with slow in vitro dissociation and in vivo protein digestion blocking.</p>
    Formula:C22H22N4O8·xH2O
    Color and Shape:Solid
  • PNU-248686A

    CAS:
    <p>PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).</p>
    Formula:C22H18ClNaO5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:484.95
  • CM-352

    CAS:
    <p>CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.</p>
    Formula:C24H29N3O6S
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:487.57
  • DPP-4-IN-15

    CAS:
    <p>DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 8.24 μM.</p>
    Formula:C17H14F3N3O2S
    Color and Shape:Solid
    Molecular weight:381.372
  • UK 356618

    CAS:
    <p>UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).</p>
    Formula:C34H43N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:557.72
  • Verducatib

    CAS:
    <p>Verducatib is an inhibitor of cathepsins (cathepsin).</p>
    Formula:C31H35FN4O3
    Color and Shape:Solid
    Molecular weight:530.633
  • Anti-infective agent 10

    CAS:
    <p>Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.</p>
    Formula:C26H25N3O7S
    Color and Shape:Solid
    Molecular weight:523.56
  • HCV-IN-40

    CAS:
    <p>HCV-IN-39 is a potent oral drug inhibiting HCV, effective on GT1a (EC50: 0.259μM), GT1b (EC50: 0.434μM), GT1b CES1 (EC50: 0.069μM) replicons.</p>
    Formula:C21H26BrFN3O9P
    Color and Shape:Solid
    Molecular weight:594.32
  • RBx-0597

    CAS:
    <p>RBx-0597 is a selective DPP-IV inhibitor with IC50 values of 32 nM, 31 nM, and 39 nM for human, mouse, and rat plasma DPP-IV, respectively. It is utilized in research focused on type 2 diabetes.</p>
    Formula:C19H20F2N4O2
    Color and Shape:Solid
    Molecular weight:374.384
  • GB111-NH2

    CAS:
    <p>GB111-NH2, a cysteine cathepsin inhibitor, is applicable in cancer research [1].</p>
    Formula:C33H39N3O6
    Color and Shape:Solid
    Molecular weight:573.68
  • Marizomib

    CAS:
    <p>Marizomib is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L, CT-T-laspase-like, and trypsin-like 20S proteasomes.Cost-effective and quality-assured.</p>
    Formula:C15H20ClNO4
    Purity:98.03% - 99.41%
    Color and Shape:Solid
    Molecular weight:313.78
  • GSK5852


    <p>GSK5852, an HCV NS5B inhibitor, has IC50 of 50 nM; potently fights HCV with EC50 of 3.0 nM for GT1a and 1.7 nM for GT1b.</p>
    Formula:C27H27BF2N2O6S
    Color and Shape:Solid
    Molecular weight:556.39
  • Odiparcil

    CAS:
    <p>Odiparcil is an orally active beta-d-thioxyloside analog.</p>
    Formula:C15H16O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.35
  • BI-1942

    CAS:
    <p>BI-1942 is a chymase inhibitor with an IC50 value of 0.4 nM against human chymase. It is applicable for research in ophthalmic diseases.</p>
    Formula:C24H26N4O4
    Color and Shape:Solid
    Molecular weight:434.488
  • Freselestat quarterhydrate


    <p>ONO-6818 quarterhydrate: oral neutrophil elastase inhibitor, Ki 12.2 nM; &gt;100x less effective on other proteases; strong anti-inflammatory.</p>
    Formula:C23H30N6O5
    Color and Shape:Solid
    Molecular weight:457.03
  • Plodicitinib

    CAS:
    <p>Plodicitinib is an inhibitor of Janus tyrosine kinase 3/TEC family kinase, exhibiting anti-inflammatory properties.</p>
    Formula:C19H22FN7O2
    Color and Shape:Solid
    Molecular weight:399.422
  • CatD-IN-1

    CAS:
    <p>CatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM, and it shows potential for research in the field of osteoarthritis.</p>
    Formula:C18H18Cl2N4O5
    Color and Shape:Solid
    Molecular weight:441.265
  • Matriptase-IN-2 free base

    CAS:
    <p>Matriptase-IN-2 free base, a matriptase inhibitor with a K i of 5 nM, has potential applications in musculoskeletal system disorder research (WO2011023958A1; compound 432) [1].</p>
    Formula:C29H33Cl2N5O3S
    Color and Shape:Solid
    Molecular weight:602.58
  • GLS-1-IN-1


    <p>GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.</p>
    Formula:C26H25FN4OS
    Color and Shape:Solid
    Molecular weight:460.57
  • Valopicitabine

    CAS:
    <p>Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic</p>
    Formula:C15H24N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:356.37
  • SSR-182289A (Free)

    CAS:
    <p>SSR-182289A (Free) is a thrombin inhibitor.</p>
    Formula:C30H33F2N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:597.68
  • BMT-052

    CAS:
    <p>BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).</p>
    Formula:C30H17D9F4N6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:635.61
  • Tilpisertib fosmecarbil

    CAS:
    <p>Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.</p>
    Formula:C35H36ClN8O7P
    Color and Shape:Solid
    Molecular weight:747.14
  • Monosodium 2-sulfoterephthalate

    CAS:
    <p>Monosodium 2-sulfoterephthalate (8) is an inhibitor of glutamate carboxypeptidase II.</p>
    Formula:C8H5NaO7S
    Color and Shape:Solid
    Molecular weight:268.176
  • Idraparinux Na

    CAS:
    <p>Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa Inhibitor</p>
    Formula:C38H55Na9O49S7
    Color and Shape:Solid
    Molecular weight:1727.14
  • HCV-IN-7

    CAS:
    <p>HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.</p>
    Formula:C40H48N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:768.92
  • Tyrosinase-IN-37

    CAS:
    <p>Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.</p>
    Formula:C12H12N6S
    Color and Shape:Solid
    Molecular weight:272.33
  • BI 224436

    CAS:
    <p>BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.</p>
    Formula:C27H26N2O4
    Color and Shape:Solid
    Molecular weight:442.51
  • ZINC09518833

    CAS:
    <p>ZINC09518833 is an α-ketoamide non-peptide proteasome inhibitor with an IC50 value of 12.4 μM. It can bind with both the active and inactive sites of the proteasome. ZINC09518833 shows promise for use in research related to multiple myeloma (MM).</p>
    Formula:C24H25N3O5
    Color and Shape:Solid
    Molecular weight:435.47
  • Napsagatran hydrate

    CAS:
    <p>Napsagatran hydrate is a novel and specific inhibitor of thrombin.</p>
    Formula:C26H36N6O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:576.66
  • Dup-714

    CAS:
    <p>Dup-714 is a thrombin inhibitor.</p>
    Formula:C21H33BN6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:460.33
  • Feniralstat

    CAS:
    <p>Feniralstat (KVD-824) is a selective and potent kallikrein (kallikrein) inhibitor, useful in immune system diseases and cardiovascular disease research.</p>
    Formula:C26H25F2N5O4
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:509.51
  • M826


    <p>M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity in</p>
    Formula:C28H45N7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:575.7
  • Cathepsin K inhibitor 2

    CAS:
    <p>Cathepsin K inhibitor 2 targets CTSK gene, may treat osteoporosis and osteoarthritis, detailed in patent WO2021147882A1.</p>
    Formula:C30H33F4N5O3
    Color and Shape:Solid
    Molecular weight:587.61
  • (2S,4R)-Teneligliptin

    CAS:
    <p>(2S,4R)-Teneligliptin is a selective inhibitor of dipeptidyl peptidase IV (DPP-4). It increases the concentration of active glucagon-like peptide-1 (GLP-1) in plasma, which in turn stimulates insulin secretion when blood glucose levels are elevated, thereby exhibiting hypoglycemic effects. (2S,4R)-Teneligliptin is a promising candidate for research in type 2 diabetes.</p>
    Formula:C22H30N6OS
    Color and Shape:Solid
    Molecular weight:426.578
  • Kallikrein-IN-1

    CAS:
    <p>Kallikrein-IN-1 (Formula A) is an inhibitor of the kinin-releasing enzyme Kallikrein.</p>
    Formula:C28H26FN5O4
    Color and Shape:Solid
    Molecular weight:515.54
  • TCL1

    CAS:
    <p>TCL1 acts as a selective non-covalent inhibitor targeting the Pru domain of the Rpn-13 subunit within the 19S regulatory particle (19S RP) of the proteasome, with an IC50 value around 26 μM. It disrupts the recognition and transport of ubiquitinated proteins by Rpn-13, thus inhibiting proteasomal degradation and affecting intracellular protein metabolism balance. TCL1 holds potential for research in hematologic malignancies.</p>
    Formula:C19H14BrClN4O2S
    Color and Shape:Solid
    Molecular weight:477.762
  • Cathepsin C-IN-5

    CAS:
    <p>Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.</p>
    Formula:C21H17ClN6OS
    Color and Shape:Solid
    Molecular weight:436.92
  • GSK-2878175

    CAS:
    <p>GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>
    Formula:C27H23BClFN2O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:568.81
  • Piceid 6″-O-azelaic acid ester


    <p>Piceid 6″-O-azelaic acid ester exhibited strong intracellular tyrosinase inhibition and decolorization activity.</p>
    Formula:C24H36O10
    Color and Shape:Solid
    Molecular weight:484.54
  • ABT-072

    CAS:
    <p>ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.</p>
    Formula:C24H27N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.55
  • Cyclophilin inhibitor 1

    CAS:
    <p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>
    Formula:C31H39N5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:593.67
  • Ciluprevir

    CAS:
    <p>Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.</p>
    Formula:C40H50N6O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:774.93
  • MK-8876

    CAS:
    <p>MK-8876 is an Inhibitor of HCV NS5B Site D.</p>
    Formula:C32H24F2N4O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:614.62
  • GW311616

    CAS:
    <p>GW-311616 is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).</p>
    Formula:C19H31N3O4S
    Color and Shape:Solid
    Molecular weight:397.53
  • MeO-Suc-Ala-Ala-Pro-Ala-CMK

    CAS:
    <p>MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE) with an IC50 of 20.3 μM. It effectively inhibits the hydrolysis of substrates like lung tissue elastin by HNE and is applicable in studies related to conditions such as chronic obstructive pulmonary disease (COPD).</p>
    Formula:C20H31ClN4O7
    Color and Shape:Solid
    Molecular weight:474.936
  • RIPK1-IN-26

    CAS:
    <p>RIPK1-IN-26 is a potent inhibitor of Receptor-Interacting Serine/Threonine Kinase 1 (RIPK1), exhibiting anti-necrotic properties in cells. This compound demonstrates good metabolic stability and binding specificity in mice. RIPK1-IN-26 holds potential for development as a PET imaging probe and in the research of neurodegenerative diseases.</p>
    Formula:C15H20FNO2
    Color and Shape:Solid
    Molecular weight:265.32
  • Freselestat

    CAS:
    <p>Freselestat (ONO-6818) inhibits neutrophil elastase, reduces interleukin 8, C5B-9, and inflammation in cardiopulmonary bypass.</p>
    Formula:C23H28N6O4
    Color and Shape:Solid
    Molecular weight:452.51
  • TMPRSS6-IN-1 TFA


    <p>TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), a member of the TTSP family (a type of transmembrane serine protease). TMPRSS6 is a type II TTSP, and genetically reduced levels of TMPRSS6 have been shown to improve symptoms of hemochromatosis and β-thalassemia in mice.</p>
    Formula:C35H41F3N8O6S2
    Color and Shape:Solid
    Molecular weight:790.875
  • JBJ-08-178-01

    CAS:
    <p>JBJ-08-178-01, a mutant-selective tyrosine kinase inhibitor, targets (HER2) human epidermal growth factor receptor 2 and exhibits antitumoral activity. This compound not only diminishes HER2's kinase activity and protein levels through the induction of proteasomal degradation of the receptor but also shows promise in non-small-cell lung cancer research.</p>
    Formula:C31H30N8O3
    Color and Shape:Solid
    Molecular weight:562.62