
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(36 products)
- Cysteine Protease(111 products)
- DPP-4(24 products)
- Glutaminase(44 products)
- HIV Protease(501 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(89 products)
- Serine Protease(54 products)
- p97(15 products)
Show 3 more subcategories
Found 994 products of "Proteases/Proteasome"
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Clemizole
CAS:Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.Formula:C19H20ClN3Purity:98% - 99.65%Color and Shape:SolidMolecular weight:325.84Ref: TM-T1822
1mg44.00€5mg87.00€10mg106.00€25mg160.00€50mg270.00€100mg487.00€500mg1,026.00€1mL*10mM (DMSO)87.00€Glutaminase C-IN-1
CAS:Glutaminase C-IN-1 (Compound 968) is a Glutaminase C allosteric inhibitor.Formula:C27H27BrN2OPurity:99.68% - >99.99%Color and Shape:SolidMolecular weight:475.42Ref: TM-T3964
2mg42.00€5mg60.00€10mg87.00€25mg162.00€50mg273.00€100mg378.00€200mg557.00€1mL*10mM (DMSO)67.00€Anagliptin
CAS:Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.Formula:C19H25N7O2Purity:97.59% - 99.98%Color and Shape:SolidMolecular weight:383.45Ref: TM-T7133
1mg47.00€5mg92.00€10mg137.00€25mg224.00€50mg331.00€100mg502.00€200mg715.00€1mL*10mM (DMSO)97.00€Balicatib
CAS:Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.Formula:C23H33N5O2Purity:97.78% - 98.17%Color and Shape:White To Off-White Solid PowderMolecular weight:411.54Ref: TM-T1850
2mg39.00€5mg58.00€10mg94.00€25mg212.00€50mg358.00€100mg572.00€200mg803.00€1mL*10mM (DMSO)64.00€Elvitegravir
CAS:Elvitegravir (JTK-303) is an HIV integrase inhibitor and CYP2C9 inducer.Formula:C23H23ClFNO5Purity:98.43% - 99.57%Color and Shape:SolidMolecular weight:447.88TAPI-1 trifluoroacetate (163847-77-6(free base))
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.Formula:C28H38F3N5O7Purity:98.06%Color and Shape:SolidMolecular weight:613.62L-Albizziin
CAS:L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.Formula:C4H9N3O3Purity:99.98%Color and Shape:White PowderMolecular weight:147.13CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)
CTTHWGFTLC, CYCLIC acetate is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9.Formula:C54H75N13O16S2Purity:99.71%Color and Shape:SolidMolecular weight:1226.39Dabigatran
CAS:Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.Formula:C25H25N7O3Purity:97.44% - 98.7%Color and Shape:Tan SolidMolecular weight:471.51Samatasvir
CAS:Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.Formula:C47H48N8O6S2Purity:98.03%Color and Shape:SolidMolecular weight:885.06Ref: TM-T9567
1mg55.00€5mg116.00€10mg187.00€25mg376.00€50mg632.00€100mg1,008.00€1mL*10mM (DMSO)197.00€Trelagliptin succinate
CAS:Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (Formula:C22H26FN5O6Purity:99.27% - 99.92%Color and Shape:SolidMolecular weight:475.47Omarigliptin
CAS:Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.Formula:C17H20F2N4O3SPurity:99.68% - 99.77%Color and Shape:SolidMolecular weight:398.43Ref: TM-T2316
1mg38.00€2mg50.00€5mg80.00€10mg117.00€25mg200.00€50mg333.00€100mg477.00€500mg1,063.00€1mL*10mM (DMSO)131.00€2-Cyanopyrimidine
CAS:2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)Formula:C5H3N3Purity:99.27%Color and Shape:Crystalline SolidMolecular weight:105.1GK921
CAS:GK921 is a transglutaminase 2 (TGase) inhibitor.Formula:C21H20N4OPurity:97.44% - 99.49%Color and Shape:SolidMolecular weight:344.41Tris(4-aminophenyl)methane
CAS:Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.Formula:C19H19N3Purity:95.73%Color and Shape:Beige Solid CrystallineMolecular weight:289.37KKI-5 acetate(97145-43-2 free base)
KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.Formula:C37H59N11O11Purity:99.44%Color and Shape:SolidMolecular weight:833.95JNJ0966
CAS:JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).Formula:C16H16N4O2S2Purity:99.46% - 99.62%Color and Shape:SolidMolecular weight:360.45Ref: TM-T4783
2mg34.00€5mg46.00€10mg64.00€25mg126.00€50mg219.00€100mg315.00€200mg434.00€1mL*10mM (DMSO)35.00€Saxagliptin
CAS:Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.Formula:C18H25N3O2Purity:99.17% - 99.95%Color and Shape:SolidMolecular weight:315.41S 3304
CAS:S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.Formula:C24H20N2O4S2Purity:98.09%Color and Shape:SolidMolecular weight:464.56Ref: TM-T16966
1mg42.00€2mg60.00€5mg105.00€10mg170.00€25mg281.00€50mg395.00€100mg537.00€200mg725.00€1mL*10mM (DMSO)108.00€MUN57694
CAS:MUN57694 is an inhibitor of 26S proteasome.Formula:C23H25N3O4Purity:99%Color and Shape:SolidMolecular weight:407.46Ref: TM-T9090
2mg35.00€5mg52.00€10mg86.00€25mg145.00€50mg210.00€100mg296.00€200mg414.00€1mL*10mM (DMSO)64.00€Velpatasvir
CAS:Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.Formula:C49H54N8O8Purity:99.17% - 99.83%Color and Shape:SolidMolecular weight:883Ref: TM-T3334
5mg34.00€10mg49.00€25mg79.00€50mg98.00€100mg152.00€200mg219.00€500mg358.00€1mL*10mM (DMSO)54.00€Paritaprevir
CAS:Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂,对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 1.31 μM。
Formula:C40H43N7O7SPurity:99.72%Color and Shape:SolidMolecular weight:765.88Efegatran
CAS:Efegatran is a hematologic agent and platelet aggregation inhibitor.
Formula:C21H32N6O3Color and Shape:SolidMolecular weight:416.527-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS:7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a inhibitor of Hepatitis C Virus(HCV).Formula:C15H16N4Purity:99.22%Color and Shape:SolidMolecular weight:252.31Belnacasan
CAS:Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Formula:C24H33ClN4O6Purity:96.53% - 99.5%Color and Shape:SolidMolecular weight:508.99Ref: TM-T6090
2mg37.00€5mg50.00€10mg86.00€25mg170.00€50mg235.00€100mg419.00€200mg617.00€1mL*10mM (DMSO)56.00€Avatrombopag
CAS:Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiationFormula:C29H34Cl2N6O3S2Purity:99.01% - 99.63%Color and Shape:SolidMolecular weight:649.65Ref: TM-T7417
1mg57.00€5mg120.00€10mg187.00€25mg339.00€50mg540.00€100mg747.00€200mg1,035.00€1mL*10mM (DMSO)167.00€Telaprevir
CAS:Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).Formula:C36H53N7O6Purity:96.9% - 98.89%Color and Shape:SolidMolecular weight:679.85S-methyl-KE-298
CAS:S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) productionFormula:C13H16O3SPurity:97.33%Color and Shape:SolidMolecular weight:252.33Ref: TM-T4282
1mg88.00€5mg210.00€10mg338.00€25mg625.00€50mg938.00€100mg1,264.00€1mL*10mM (DMSO)188.00€NSC 405020
CAS:NSC 405020 is a noncatalytic inhibitor of MT1-MMP.Formula:C12H15Cl2NOPurity:96.93% - 99.07%Color and Shape:SolidMolecular weight:260.16MDL-28170
CAS:MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.Formula:C22H26N2O4Purity:95.06%Color and Shape:SolidMolecular weight:382.45Ref: TM-T2470
1mg34.00€2mg49.00€5mg71.00€10mg90.00€25mg128.00€50mg167.00€100mg284.00€1mL*10mM (DMSO)75.00€Ombitasvir
CAS:Ombitasvir (ABT-267) inhibits HCV protein NS5A, effective orally, EC50: 0.82-19.3 pM (genotypes 1-5), 366 pM (genotype 6a).Formula:C50H67N7O8Purity:97.27% - 99.56%Color and Shape:SolidMolecular weight:894.11Ref: TM-T7158
2mg40.00€5mg75.00€10mg105.00€25mg215.00€50mg313.00€100mg462.00€500mg973.00€1mL*10mM (DMSO)105.00€4-Butylresorcinol
CAS:4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.Formula:C10H14O2Purity:99.48% - ≥95%Color and Shape:Light Beige Solid PowderMolecular weight:166.22LY 3000328
CAS:LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.Formula:C25H29FN4O5Purity:97.83% - 99.54%Color and Shape:SolidMolecular weight:484.52Ref: TM-TQ0116
1mg90.00€2mg130.00€5mg198.00€10mg263.00€25mg462.00€50mg672.00€100mg945.00€1mL*10mM (DMSO)207.00€SB-734117
CAS:SB-734117 inhibits productive replication of several HCMV strains.Formula:C14H16N6OPurity:99.72%Color and Shape:SolidMolecular weight:284.32Ref: TM-T9580
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)235.00€2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one
CAS:2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.Formula:C14H7BrClNO2Purity:97.36%Color and Shape:SolidMolecular weight:336.57Talabostat mesylate
CAS:Talabostat mesylate (PT100): Oral DPP4 inhibitor, IC50 0.18 nM, targets tumor-linked proteins, boosts hematopoiesis.
Formula:C10H23BN2O6SPurity:98% - 99.91%Color and Shape:SolidMolecular weight:310.18Letermovir
CAS:Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.Formula:C29H28F4N4O4Purity:99.85% - 99.87%Color and Shape:SolidMolecular weight:572.55Ref: TM-T5396
1mg84.00€5mg167.00€10mg268.00€25mg470.00€50mg670.00€100mg954.00€200mg1,288.00€1mL*10mM (DMSO)205.00€Bemnifosbuvir
CAS:Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.Formula:C24H33FN7O7PPurity:99.35% - 99.54%Color and Shape:SolidMolecular weight:581.53KGP94
CAS:KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.Formula:C14H12BrN3OSPurity:99.6%Color and Shape:SolidMolecular weight:350.23Ref: TM-T27730
1mg65.00€5mg138.00€10mg215.00€25mg359.00€50mg510.00€100mg692.00€200mg928.00€1mL*10mM (DMSO)152.00€NQ301
CAS:NQ301, an antithrombotic agent, inhibits collagen-challenged rabbit platelet aggregation (IC50: 10 mg/mL).Formula:C18H12ClNO3Purity:99.74% - 99.76%Color and Shape:SolidMolecular weight:325.75Clemizole hydrochloride
CAS:Clemizole hydrochloride blocks H1 histamine receptors and inhibits HCV replication and NS4B RNA binding.Formula:C19H21Cl2N3Purity:>99.99%Color and Shape:SolidMolecular weight:362.3CA-074 methyl ester
CAS:CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!Formula:C19H31N3O6Purity:97.26% - 99.58%Color and Shape:SolidMolecular weight:397.474-Phenoxybenzylamine
CAS:4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .Formula:C13H13NOPurity:97.26%Color and Shape:SolidMolecular weight:199.25TCH-165
CAS:TCH-165 boosts 20S proteasome levels, enhancing IDP breakdown.Formula:C39H37N3O3Purity:98.2% - 98.75%Color and Shape:SolidMolecular weight:595.73Ref: TM-T17011
1mg71.00€5mg152.00€10mg236.00€25mg432.00€50mg647.00€100mg888.00€200mg1,198.00€1mL*10mM (DMSO)193.00€Daclatasvir dihydrochloride
CAS:Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.Formula:C40H52Cl2N8O6Purity:99.67%Color and Shape:SolidMolecular weight:811.8Ref: TM-T1786
1g230.00€5mg39.00€10mg48.00€25mg57.00€50mg67.00€100mg77.00€500mg161.00€1mL*10mM (DMSO)49.00€Tenofovir alafenamide hemifumarate
CAS:Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir.
Formula:C21H29N6O5PC4H4O4Purity:99.33% - 99.96%Color and Shape:SolidMolecular weight:534.51Ilomastat
CAS:Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor.Formula:C20H28N4O4Purity:97.04% - 99.51%Color and Shape:SolidMolecular weight:388.46Ref: TM-T2743
1mg46.00€2mg62.00€5mg89.00€10mg145.00€25mg255.00€50mg429.00€100mg620.00€200mg880.00€1mL*10mM (DMSO)94.00€Coblopasvir
CAS:Coblopasvir is a pan-genotypic non-structural protein 5A (NS5A) inhibitor. It can be used to study chronic hepatitis C virus infection.Formula:C41H50N8O8Purity:99.33%Color and Shape:SolidMolecular weight:782.88Voxilaprevir
CAS:Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease.Formula:C40H52F4N6O9SPurity:99.83% - 99.98%Color and Shape:SolidMolecular weight:868.93Ref: TM-T19862
1mg75.00€5mg295.00€10mg423.00€25mg708.00€50mg954.00€100mg1,288.00€200mg1,738.00€1mL*10mM (DMSO)394.00€Daclatasvir
CAS:Daclatasvir (EBP 883/BMS-790052) is a potent HCV NS5A inhibitor with EC50 9-50 pM across various genotypes. Phase 3.Formula:C40H50N8O6Purity:99.81% - 99.99%Color and Shape:SolidMolecular weight:738.88
