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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Dabigatran ethyl ester

    CAS:
    <p>Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.</p>
    Formula:C27H29N7O3
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:499.56
  • Ubenimex

    CAS:
    Formula:C16H24N2O4
    Purity:>98.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:308.38

    Ref: 3B-U0111

    1g
    416.00€
    250mg
    136.00€
  • Diprotin A TFA

    CAS:
    <p>Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).</p>
    Formula:C19H32F3N3O6
    Color and Shape:Solid
    Molecular weight:455.47
  • H-Pro-Lys-OH TFA


    <p>H-Pro-Lys-OH TFA is a dipeptide composed of proline and lysine, serving as a substrate for imino dipeptidase (prolinase). Additionally, it can be utilized in peptide synthesis.</p>
    Formula:C13H22F3N3O5
    Color and Shape:Solid
    Molecular weight:357.33
  • PD-166793

    CAS:
    <p>PD-166793 is an MMP inhibitor with inhibitory effects on MMP-2, MMP-3 and MMP-13.PD-166793 improves myocardial ischemia in a rat heart failure model.</p>
    Formula:C17H18BrNO4S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:412.3
  • Saxagliptin hydrochloride

    CAS:
    <p>Saxagliptin: oral DPP-4 inhibitor, enhances incretins, manages type 2 diabetes by reducing glucose levels.</p>
    Formula:C18H26ClN3O2
    Color and Shape:Solid
    Molecular weight:351.87
  • Pentosan Polysulfate Sodium (W/W 43%)

    CAS:
    <p>Pentosan Polysulfate Sodium: anti-HIV, anti-inflammatory, aids cartilage, treats interstitial cystitis.</p>
    Purity:98%
    Color and Shape:Solid
    Molecular weight:N/A
  • Alogliptin (13CD3)

    CAS:
    <p>Alogliptin (SYR-322) 13CD3 is the deuterium-labeled Alogliptin. Alogliptin is a selective inhibitor of DPP-4.</p>
    Formula:C18H21N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:343.4
  • Chlorcyclizine

    CAS:
    <p>CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.</p>
    Formula:C18H21ClN2
    Purity:98.75%
    Color and Shape:Solid
    Molecular weight:300.83
  • Coblopasvir

    CAS:
    <p>Coblopasvir is a pan-genotypic non-structural protein 5A (NS5A) inhibitor. It can be used to study chronic hepatitis C virus infection.</p>
    Formula:C41H50N8O8
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:782.88
  • Raltegravir

    CAS:
    <p>Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV</p>
    Formula:C20H21FN6O5
    Purity:99.86% - >99.99%
    Color and Shape:Solid
    Molecular weight:444.42
  • KGP94

    CAS:
    <p>KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.</p>
    Formula:C14H12BrN3OS
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:350.23
  • JNJ0966

    CAS:
    <p>JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).</p>
    Formula:C16H16N4O2S2
    Purity:99.46% - 99.62%
    Color and Shape:Solid
    Molecular weight:360.45
  • Anagliptin hydrochloride

    CAS:
    <p>Anagliptin (SK-0403) hydrochloride: potent, selective oral DPP-4 inhibitor; IC50: DPP-4 3.8 nM, DPP-8 68 nM, DPP-9 60 nM.</p>
    Formula:C19H26ClN7O2
    Color and Shape:Solid
    Molecular weight:419.91
  • Efegatran

    CAS:
    <p>Efegatran is a hematologic agent and platelet aggregation inhibitor.</p>
    Formula:C21H32N6O3
    Color and Shape:Solid
    Molecular weight:416.52
  • Raltegravir potassium

    CAS:
    <p>Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.</p>
    Formula:C20H20FN6O5·K
    Purity:98% - 99.55%
    Color and Shape:Off-White Solid
    Molecular weight:482.51
  • Tris(4-aminophenyl)methane

    CAS:
    <p>Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.</p>
    Formula:C19H19N3
    Purity:95.73%
    Color and Shape:Beige Solid Crystalline
    Molecular weight:289.37
  • 2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1λ*6*-BENZO[D]ISOTHIAZOL-3-ONE

    CAS:
    <p>2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).</p>
    Formula:C8H6ClNO3S
    Purity:97.28%
    Color and Shape:Solid
    Molecular weight:231.66
  • Delavirdine mesylate

    CAS:
    <p>Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).</p>
    Formula:C23H32N6O6S2
    Purity:99.99%
    Color and Shape:Light Brown Solid
    Molecular weight:552.67
  • ML281

    CAS:
    <p>ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.</p>
    Formula:C22H19N3O2S
    Purity:99.12% - 99.87%
    Color and Shape:Solid
    Molecular weight:389.47
  • Ximelagatran

    CAS:
    <p>Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.</p>
    Formula:C24H35N5O5
    Purity:95.48% - 99.60%
    Color and Shape:Solid
    Molecular weight:473.57
  • Dolutegravir

    CAS:
    <p>Dolutegravir (GSK1349572), HIV integrase inhibitor with IC50 of 2.7 nM, partly effective against some raltegravir-resistant HIV strains.</p>
    Formula:C20H19F2N3O5
    Purity:98.97% - 99.75%
    Color and Shape:White To Pale Yellow Solid
    Molecular weight:419.38
  • Fostemsavir

    CAS:
    <p>Fostemsavir (BMS-663068) is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.</p>
    Formula:C25H26N7O8P
    Purity:98.95%
    Color and Shape:Solid
    Molecular weight:583.49
  • KKI-5 acetate(97145-43-2 free base)


    <p>KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.</p>
    Formula:C37H59N11O11
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:833.95
  • Ditiocarb sodium

    CAS:
    <p>Ditiocarb sodium (Sodium diethyldithiocarbamate) (sodium diethiocarbamate) is a copper reagent, which reacts with Cu2 + solution to form a complex and improves</p>
    Formula:C5H10NNaS2
    Purity:98.04%
    Color and Shape:White Solid Crystalline
    Molecular weight:171.26
  • Ivachtin

    CAS:
    <p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>
    Formula:C20H21N3O7S
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:447.46
  • S 3304

    CAS:
    <p>S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.</p>
    Formula:C24H20N2O4S2
    Purity:98.09%
    Color and Shape:Solid
    Molecular weight:464.56
  • Velpatasvir

    CAS:
    <p>Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.</p>
    Formula:C49H54N8O8
    Purity:99.17% - 99.83%
    Color and Shape:Solid
    Molecular weight:883
  • Boc-Asp(OMe)-fluoromethyl ketone

    CAS:
    <p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>
    Formula:C11H18FNO5
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:263.26
  • Bemnifosbuvir hemisulfate

    CAS:
    <p>Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication.</p>
    Formula:C48H68F2N14O18P2S
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:1261.15
  • Lusutrombopag

    CAS:
    <p>Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with</p>
    Formula:C29H32Cl2N2O5S
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:591.55
  • RN-18

    CAS:
    <p>RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).</p>
    Formula:C20H16N2O4S
    Purity:97.21% - 98.39%
    Color and Shape:Solid
    Molecular weight:380.42
  • Paritaprevir

    CAS:
    <p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂,对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 1.31 μM。</p>
    Formula:C40H43N7O7S
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:765.88
  • Avatrombopag

    CAS:
    <p>Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation</p>
    Formula:C29H34Cl2N6O3S2
    Purity:99.01% - 99.63%
    Color and Shape:Solid
    Molecular weight:649.65
  • Obefazimod

    CAS:
    <p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>
    Formula:C16H10ClF3N2O
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:338.71
  • 4-Butylresorcinol

    CAS:
    <p>4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.</p>
    Formula:C10H14O2
    Purity:98.64% - ≥95%
    Color and Shape:Light Beige Solid Powder
    Molecular weight:166.22
  • Etravirine

    CAS:
    <p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>
    Formula:C20H15BrN6O
    Purity:97.61% - 99.74%
    Color and Shape:White To Off-White Solid
    Molecular weight:435.28
  • TAPI-1 trifluoroacetate (163847-77-6(free base))


    <p>TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.</p>
    Formula:C28H38F3N5O7
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:613.62
  • Grazoprevir

    CAS:
    <p>Grazoprevir (MK-5172) is a protease inhibitor targeting hepatitis C virus NS3/4A used for treating chronic HCV genotypes 1 or 4 infections. Cost-effective and quality-assured.</p>
    Formula:C38H50N6O9S
    Purity:99.36% - >99.99%
    Color and Shape:Solid
    Molecular weight:766.9
  • Dabigatran Etexilate Mesylate

    CAS:
    <p>Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.</p>
    Formula:C34H41N7O5·CH4O3S
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:723.84
  • LY 3000328

    CAS:
    <p>LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.</p>
    Formula:C25H29FN4O5
    Purity:97.83% - 99.54%
    Color and Shape:Solid
    Molecular weight:484.52
  • Daclatasvir dihydrochloride

    CAS:
    <p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>
    Formula:C40H52Cl2N8O6
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:811.8
  • (S,S)-TAPI-1

    CAS:
    <p>"(S,S)-TAPI-1, an isomer of TAPI-1, inhibits MMPs and TACE (ADAM17), reducing cell surface protein shedding."</p>
    Formula:C26H37N5O5
    Color and Shape:Solid
    Molecular weight:499.6
  • Letermovir

    CAS:
    <p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>
    Formula:C29H28F4N4O4
    Purity:99.85% - 99.87%
    Color and Shape:Solid
    Molecular weight:572.55
  • Darunavir

    CAS:
    <p>Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>
    Formula:C27H37N3O7S
    Purity:99.67% - 99.76%
    Color and Shape:White Amorphous Solid
    Molecular weight:547.66
  • Coblopasvir dihydrochloride

    CAS:
    <p>Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.</p>
    Formula:C41H52Cl2N8O8
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:855.81
  • TCH-165

    CAS:
    <p>TCH-165 boosts 20S proteasome levels, enhancing IDP breakdown.</p>
    Formula:C39H37N3O3
    Purity:98.2% - 98.75%
    Color and Shape:Solid
    Molecular weight:595.73
  • Bemnifosbuvir

    CAS:
    <p>Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.</p>
    Formula:C24H33FN7O7P
    Purity:99.35% - 99.54%
    Color and Shape:Solid
    Molecular weight:581.53
  • CA-074 methyl ester

    CAS:
    <p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>
    Formula:C19H31N3O6
    Purity:97.26% - 99.58%
    Color and Shape:Solid
    Molecular weight:397.47
  • Peptide T acetate(106362-32-7 free base)


    <p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>
    Formula:C37H59N9O18
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:917.91