
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(38 products)
- Cysteine Protease(111 products)
- DPP-4(27 products)
- Glutaminase(45 products)
- HIV Protease(506 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(87 products)
- Serine Protease(54 products)
- p97(15 products)
Show 3 more subcategories
Found 986 products of "Proteases/Proteasome"
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ND-378
CAS:ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.Formula:C18H19NO4S2Purity:98%Color and Shape:SolidMolecular weight:377.48ONO 4817
CAS:ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.Formula:C22H28N2O6Color and Shape:SolidMolecular weight:416.47NS5A-IN-3
CAS:NS5A-IN-3 is a potent NS5A inhibitor with high efficacy against HCV 1b, good activity on 3a, and strong metabolic stability; superior to daclatasvir.Formula:C44H44N6O8Purity:98%Color and Shape:SolidMolecular weight:784.86NS5A-IN-2
CAS:NS5A-IN-2, a potent inhibitor, is highly effective against HCV 1b and shows increased activity for GT 3a with good metabolic stability.Formula:C46H45N7O7Purity:98%Color and Shape:SolidMolecular weight:807.89TP0556351
CAS:TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.Formula:C50H70N10O16Purity:98%Color and Shape:SolidMolecular weight:1067.15GS-6620
CAS:GS-6620 is a HCV nonstructural protein 5B (NS5B) inhibitor.Formula:C29H37N6O9PColor and Shape:SolidMolecular weight:644.61Ro 32-7315
CAS:Ro 32-7315 is a selective inhibitor of ADAM17.Formula:C22H35N3O5SPurity:98%Color and Shape:SolidMolecular weight:453.6NCI-B16
CAS:NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].Formula:C27H26N8O4Color and Shape:SolidMolecular weight:526.55Berotralstat HCl
CAS:Berotralstat HCl is a selective plasma kallikrein inhibitor, reducing pain and swelling in HAE by blocking bradykinin release.Formula:C30H28Cl2F4N6OColor and Shape:SolidMolecular weight:635.4886Kallikrein-IN-2
CAS:Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.Formula:C28H25F3N4O4Color and Shape:SolidMolecular weight:538.52Proteasome-IN-4
Proteasome-IN-4, a potent non-covalent inhibitor (IC50=8.39nM), halts cancer cell growth, useful for oncology studies.Formula:C44H58N6O5Color and Shape:SolidMolecular weight:750.97Cathepsin K inhibitor 3
CAS:Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.Formula:C30H31FN4O4SColor and Shape:SolidMolecular weight:562.65MMP-9 Inhibitor I
CAS:MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively).Formula:C27H33N3O5SColor and Shape:SolidMolecular weight:511.63Ravidasvir HCl
CAS:Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.Formula:C42H52Cl2N8O6Color and Shape:SolidMolecular weight:835.828Cathepsin Inhibitor 2
CAS:Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).Formula:C19H21F6N3OPurity:98%Color and Shape:SolidMolecular weight:421.38Atecegatran metoxil
CAS:Atecegatran Metoxil (AZD0837), an oral thrombin inhibitor in development for stroke prevention in atrial fibrillation, is well-tolerated with favorable PK.Formula:C22H23ClF2N4O5Color and Shape:SolidMolecular weight:496.89Cyclotheonellazole A
CAS:Cyclotheonellazole A inhibits elastase (IC50=0.034nM) & chymotrypsin (IC50=0.62nM), a natural macrocyclic peptide.Formula:C44H54N9NaO14S2Color and Shape:SolidMolecular weight:1020.07Inogatran
CAS:Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.Formula:C21H38N6O4Purity:98%Color and Shape:SolidMolecular weight:438.56LY52
CAS:LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.Formula:C22H24N4O6Purity:98%Color and Shape:SolidMolecular weight:440.45MMP-7-IN-2
CAS:MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.Formula:C28H40ClF3N6O9SPurity:97.82%Color and Shape:SolidMolecular weight:729.17

