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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 994 products of "Proteases/Proteasome"

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  • DPP-4-IN-15

    CAS:
    DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 8.24 μM.
    Formula:C17H14F3N3O2S
    Color and Shape:Solid
    Molecular weight:381.372

    Ref: TM-T205036

    10mg
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    50mg
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  • SBI-581


    SBI-581: oral, potent TAO3 inhibitor, IC50=42nM, alters TKS5α at RAB11+ vesicles, blocks invadopodia, good mouse pharmacokinetics, anti-tumor.
    Formula:C24H21N3O2
    Color and Shape:Solid
    Molecular weight:383.44

    Ref: TM-T61663

    25mg
    1,305.00€
    50mg
    2,088.00€
    100mg
    3,357.00€
  • UK-370106

    CAS:
    UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-
    Formula:C35H44N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:572.73

    Ref: TM-T13249

    10mg
    1,009.00€
  • Cyclophilin inhibitor 1

    CAS:
    Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.
    Formula:C31H39N5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:593.67

    Ref: TM-T10919

    25mg
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    50mg
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    100mg
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  • ABT-072

    CAS:
    ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.
    Formula:C24H27N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.55

    Ref: TM-T14086

    25mg
    1,691.00€
    50mg
    2,205.00€
    100mg
    3,345.00€
  • Cathepsin C-IN-5

    CAS:

    Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.

    Formula:C21H17ClN6OS
    Color and Shape:Solid
    Molecular weight:436.92

    Ref: TM-T62494

    25mg
    812.00€
    50mg
    1,054.00€
    100mg
    1,529.00€
  • PNU-248686A

    CAS:
    PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).
    Formula:C22H18ClNaO5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:484.95

    Ref: TM-T12511

    25mg
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    50mg
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    100mg
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  • HCV-IN-7

    CAS:
    HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.
    Formula:C40H48N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:768.92

    Ref: TM-T11548

    25mg
    2,313.00€
    50mg
    3,042.00€
    100mg
    4,140.00€
  • Idraparinux Na

    CAS:
    Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa Inhibitor
    Formula:C38H55Na9O49S7
    Color and Shape:Solid
    Molecular weight:1727.14

    Ref: TM-T70536

    25mg
    6,094.00€
    50mg
    8,082.00€
    100mg
    11,700.00€
  • Faldaprevir

    CAS:
    Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.
    Formula:C40H49BrN6O9S
    Purity:99.04% - 99.19%
    Color and Shape:Solid
    Molecular weight:869.82

    Ref: TM-T19685

    1mg
    250.00€
    5mg
    610.00€
    10mg
    853.00€
    25mg
    1,243.00€
  • GLS-1-IN-1


    GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.
    Formula:C26H25FN4OS
    Color and Shape:Solid
    Molecular weight:460.57

    Ref: TM-T62905

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • BAY-7598

    CAS:
    BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).
    Formula:C28H31N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:505.56

    Ref: TM-T10474

    25mg
    3,348.00€
    50mg
    4,213.00€
    100mg
    5,580.00€
  • GW311616 hydrochloride

    CAS:
    GW-311616 hydrochloride is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).
    Formula:C19H32ClN3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:433.99

    Ref: TM-T11525L

    1mg
    273.00€
    5mg
    818.00€
    10mg
    1,359.00€
  • Odiparcil

    CAS:
    Odiparcil is an orally active beta-d-thioxyloside analog.
    Formula:C15H16O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.35

    Ref: TM-T16377

    2mg
    161.00€
    25mg
    690.00€
    50mg
    897.00€
    100mg
    1,386.00€
  • AMG-222 tosylate

    CAS:
    AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.
    Formula:C39H47N9O6S
    Color and Shape:Solid
    Molecular weight:769.91

    Ref: TM-T71354

    25mg
    3,866.00€
    50mg
    5,111.00€
    100mg
    7,220.00€
  • BI-1942

    CAS:
    BI-1942 is a chymase inhibitor with an IC50 value of 0.4 nM against human chymase. It is applicable for research in ophthalmic diseases.
    Formula:C24H26N4O4
    Color and Shape:Solid
    Molecular weight:434.488

    Ref: TM-T205535

    10mg
    To inquire
    50mg
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  • Valopicitabine dihydrochloride

    CAS:
    Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.
    Formula:C15H25ClN4O6
    Color and Shape:Solid
    Molecular weight:392.84

    Ref: TM-T29094

    25mg
    1,170.00€
    50mg
    1,521.00€
    100mg
    2,385.00€
  • Antiplatelet agent 3

    CAS:
    Antiplatelet agent 3 (Compound K-10) is a compound with antiplatelet aggregation activity, exhibiting IC50 values of 2.55, 3.22, and 2.09 mg/mL for platelet aggregation induced by ADP, AA, and COL, respectively. It holds potential for research in cardiovascular diseases.
    Formula:C38H32N2O5
    Color and Shape:Solid
    Molecular weight:596.671

    Ref: TM-T206363

    10mg
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    50mg
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  • Plodicitinib

    CAS:
    Plodicitinib is an inhibitor of Janus tyrosine kinase 3/TEC family kinase, exhibiting anti-inflammatory properties.
    Formula:C19H22FN7O2
    Color and Shape:Solid
    Molecular weight:399.422

    Ref: TM-T206157

    10mg
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    50mg
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  • Dup-714

    CAS:
    Dup-714 is a thrombin inhibitor.
    Formula:C21H33BN6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:460.33

    Ref: TM-T27220

    25mg
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    50mg
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    100mg
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