
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(36 products)
- Cysteine Protease(111 products)
- DPP-4(24 products)
- Glutaminase(44 products)
- HIV Protease(501 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(89 products)
- Serine Protease(54 products)
- p97(15 products)
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Found 994 products of "Proteases/Proteasome"
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DPP-4-IN-15
CAS:DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 8.24 μM.Formula:C17H14F3N3O2SColor and Shape:SolidMolecular weight:381.372SBI-581
SBI-581: oral, potent TAO3 inhibitor, IC50=42nM, alters TKS5α at RAB11+ vesicles, blocks invadopodia, good mouse pharmacokinetics, anti-tumor.Formula:C24H21N3O2Color and Shape:SolidMolecular weight:383.44UK-370106
CAS:UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-Formula:C35H44N2O5Purity:98%Color and Shape:SolidMolecular weight:572.73Cyclophilin inhibitor 1
CAS:Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.Formula:C31H39N5O7Purity:98%Color and Shape:SolidMolecular weight:593.67ABT-072
CAS:ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.Formula:C24H27N3O5SPurity:98%Color and Shape:SolidMolecular weight:469.55Cathepsin C-IN-5
CAS:Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.
Formula:C21H17ClN6OSColor and Shape:SolidMolecular weight:436.92PNU-248686A
CAS:PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).Formula:C22H18ClNaO5S2Purity:98%Color and Shape:SolidMolecular weight:484.95HCV-IN-7
CAS:HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.Formula:C40H48N8O6SPurity:98%Color and Shape:SolidMolecular weight:768.92Idraparinux Na
CAS:Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa InhibitorFormula:C38H55Na9O49S7Color and Shape:SolidMolecular weight:1727.14Faldaprevir
CAS:Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.Formula:C40H49BrN6O9SPurity:99.04% - 99.19%Color and Shape:SolidMolecular weight:869.82GLS-1-IN-1
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.Formula:C26H25FN4OSColor and Shape:SolidMolecular weight:460.57BAY-7598
CAS:BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).Formula:C28H31N3O6Purity:98%Color and Shape:SolidMolecular weight:505.56GW311616 hydrochloride
CAS:GW-311616 hydrochloride is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).Formula:C19H32ClN3O4SPurity:98%Color and Shape:SolidMolecular weight:433.99Odiparcil
CAS:Odiparcil is an orally active beta-d-thioxyloside analog.Formula:C15H16O6SPurity:98%Color and Shape:SolidMolecular weight:324.35AMG-222 tosylate
CAS:AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.Formula:C39H47N9O6SColor and Shape:SolidMolecular weight:769.91BI-1942
CAS:BI-1942 is a chymase inhibitor with an IC50 value of 0.4 nM against human chymase. It is applicable for research in ophthalmic diseases.Formula:C24H26N4O4Color and Shape:SolidMolecular weight:434.488Valopicitabine dihydrochloride
CAS:Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.Formula:C15H25ClN4O6Color and Shape:SolidMolecular weight:392.84Antiplatelet agent 3
CAS:Antiplatelet agent 3 (Compound K-10) is a compound with antiplatelet aggregation activity, exhibiting IC50 values of 2.55, 3.22, and 2.09 mg/mL for platelet aggregation induced by ADP, AA, and COL, respectively. It holds potential for research in cardiovascular diseases.Formula:C38H32N2O5Color and Shape:SolidMolecular weight:596.671Plodicitinib
CAS:Plodicitinib is an inhibitor of Janus tyrosine kinase 3/TEC family kinase, exhibiting anti-inflammatory properties.Formula:C19H22FN7O2Color and Shape:SolidMolecular weight:399.422Dup-714
CAS:Dup-714 is a thrombin inhibitor.Formula:C21H33BN6O5Purity:98%Color and Shape:SolidMolecular weight:460.33

