
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(36 products)
- Cysteine Protease(111 products)
- DPP-4(24 products)
- Glutaminase(44 products)
- HIV Protease(501 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(89 products)
- Serine Protease(54 products)
- p97(15 products)
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Found 994 products of "Proteases/Proteasome"
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Histatin 5
CAS:Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.Formula:C133H195N51O33Purity:98%Color and Shape:SolidMolecular weight:3036.29Ac-Phe-Gly-pNA
CAS:Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .Formula:C19H20N4O5Color and Shape:SolidMolecular weight:384.39STK33-IN-1
CAS:STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.Formula:C24H27N7O2Color and Shape:SolidMolecular weight:445.527Ac-PAL-AMC
CAS:Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.Formula:C26H34N4O6Color and Shape:SolidMolecular weight:498.57Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Formula:C19H14BrClN4OColor and Shape:SolidMolecular weight:429.75-epi-Arvestonate A
CAS:5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.
Formula:C16H26O5Color and Shape:SolidMolecular weight:298.37LXE408 fumarate
LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.
Formula:C27H22FN7O6Purity:99.89%Color and Shape:SoildMolecular weight:559.51HCV-IN-4
CAS:HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.Formula:C52H58FN9O8Purity:98%Color and Shape:SolidMolecular weight:956.07Paritaprevir dihydrate
CAS:Paritaprevir dihydrate: potent oral HCV NS3/4A inhibitor (EC50: 0.21-1 nM), SARS-CoV-3CL blocker (IC50: 1.31 μM), metabolized by CYP3A, boosted by Ritonavir.Formula:C40H47N7O9SColor and Shape:SolidMolecular weight:801.91Peptide 74
CAS:Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.Formula:C62H107N23O20S2Purity:98%Color and Shape:SolidMolecular weight:1558.79Rivulariapeptolides 1121
Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).Formula:C56H83N9O15Color and Shape:SolidMolecular weight:1122.31BPHA
CAS:BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.Formula:C21H20N2O4SPurity:99.44%Color and Shape:SolidMolecular weight:396.46Ref: TM-T36712
1mg167.00€5mg442.00€10mg620.00€25mg954.00€50mg1,305.00€100mg1,738.00€200mg2,322.00€1mL*10mM (DMSO)442.00€HIV-1 inhibitor-6
CAS:HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicingFormula:C14H10N4O4SPurity:99.33%Color and Shape:SolidMolecular weight:330.32CRA-2059 hydrochloride
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].Color and Shape:SolidBMS-767778
CAS:BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.Formula:C19H20Cl2N4O2Color and Shape:SolidMolecular weight:407.29Enzyme-IN-1
CAS:Enzyme-IN-1(compound 1)为基于肽的N端亲核试剂(Ntn)水解酶抑制剂,特别针对20S蛋白酶体的糜胰蛋白酶样活性(CT-L)进行抑制,可能展现出抗炎特性。Formula:C36H50N4O7Color and Shape:SolidMolecular weight:650.8Fotagliptin benzoate
CAS:Fotagliptin benzoate, a DPP-4 inhibitor (IC50=2.27 nM), is safe in rats/dogs, useful for Type 2 diabetes research.Formula:C24H25FN6O3Color and Shape:SolidMolecular weight:464.49Sitagliptin fenilalanil hydrochloride
CAS:Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.Formula:C25H25ClF6N6O2Color and Shape:SolidMolecular weight:590.95PF 00356231
CAS:PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).
Formula:C25H20N2O3SPurity:99.35%Color and Shape:SolidMolecular weight:428.5Ellipyrone A
Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).Formula:C25H34O8Color and Shape:SolidMolecular weight:462.53

