CymitQuimica logo
Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

Show 3 more subcategories

Found 994 products of "Proteases/Proteasome"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Histatin 5

    CAS:
    Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.
    Formula:C133H195N51O33
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3036.29

    Ref: TM-TP1741

    1mg
    163.00€
    5mg
    562.00€
    10mg
    892.00€
  • Ac-Phe-Gly-pNA

    CAS:
    Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .
    Formula:C19H20N4O5
    Color and Shape:Solid
    Molecular weight:384.39

    Ref: TM-T74692

    5mg
    To inquire
    50mg
    To inquire
  • STK33-IN-1

    CAS:
    STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.
    Formula:C24H27N7O2
    Color and Shape:Solid
    Molecular weight:445.527

    Ref: TM-T38835

    5mg
    873.00€
  • Ac-PAL-AMC

    CAS:
    Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.
    Formula:C26H34N4O6
    Color and Shape:Solid
    Molecular weight:498.57

    Ref: TM-T37421

    1mg
    241.00€
    5mg
    945.00€
    10mg
    1,665.00€
  • Tyrosinase-IN-34


    Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.
    Formula:C19H14BrClN4O
    Color and Shape:Solid
    Molecular weight:429.7

    Ref: TM-T89968

    10mg
    To inquire
    50mg
    To inquire
  • 5-epi-Arvestonate A

    CAS:

    5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.

    Formula:C16H26O5
    Color and Shape:Solid
    Molecular weight:298.37

    Ref: TM-T75535

    5mg
    To inquire
    50mg
    To inquire
  • LXE408 fumarate


    LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.

    Formula:C27H22FN7O6
    Purity:99.89%
    Color and Shape:Soild
    Molecular weight:559.51

    Ref: TM-T39214L

    1mg
    315.00€
    2mg
    472.00€
    5mg
    595.00€
    10mg
    947.00€
    25mg
    1,396.00€
    50mg
    1,890.00€
    100mg
    2,547.00€
  • HCV-IN-4

    CAS:
    HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.
    Formula:C52H58FN9O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:956.07

    Ref: TM-TP1468

    100mg
    To inquire
    500mg
    To inquire
  • Paritaprevir dihydrate

    CAS:
    Paritaprevir dihydrate: potent oral HCV NS3/4A inhibitor (EC50: 0.21-1 nM), SARS-CoV-3CL blocker (IC50: 1.31 μM), metabolized by CYP3A, boosted by Ritonavir.
    Formula:C40H47N7O9S
    Color and Shape:Solid
    Molecular weight:801.91

    Ref: TM-T73898

    5mg
    To inquire
    50mg
    To inquire
  • Peptide 74

    CAS:
    Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.
    Formula:C62H107N23O20S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1558.79

    Ref: TM-TP2335

    100mg
    To inquire
    500mg
    To inquire
  • Rivulariapeptolides 1121


    Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).
    Formula:C56H83N9O15
    Color and Shape:Solid
    Molecular weight:1122.31

    Ref: TM-T75650

    5mg
    To inquire
    50mg
    To inquire
  • BPHA

    CAS:
    BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.
    Formula:C21H20N2O4S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46

    Ref: TM-T36712

    1mg
    167.00€
    5mg
    442.00€
    10mg
    620.00€
    25mg
    954.00€
    50mg
    1,305.00€
    100mg
    1,738.00€
    200mg
    2,322.00€
    1mL*10mM (DMSO)
    442.00€
  • HIV-1 inhibitor-6 

    CAS:
    HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing
    Formula:C14H10N4O4S
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:330.32

    Ref: TM-T9854

    1mg
    75.00€
    5mg
    169.00€
    10mg
    284.00€
    25mg
    452.00€
    50mg
    645.00€
    100mg
    867.00€
    500mg
    To inquire
  • CRA-2059 hydrochloride


    CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].
    Color and Shape:Solid

    Ref: TM-T38051

    5mg
    315.00€
    10mg
    492.00€
    25mg
    960.00€
  • BMS-767778

    CAS:
    BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.
    Formula:C19H20Cl2N4O2
    Color and Shape:Solid
    Molecular weight:407.29

    Ref: TM-T26857

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Enzyme-IN-1

    CAS:
    Enzyme-IN-1(compound 1)为基于肽的N端亲核试剂(Ntn)水解酶抑制剂,特别针对20S蛋白酶体的糜胰蛋白酶样活性(CT-L)进行抑制,可能展现出抗炎特性。
    Formula:C36H50N4O7
    Color and Shape:Solid
    Molecular weight:650.8

    Ref: TM-T74878

    5mg
    To inquire
    50mg
    To inquire
  • Fotagliptin benzoate

    CAS:
    Fotagliptin benzoate, a DPP-4 inhibitor (IC50=2.27 nM), is safe in rats/dogs, useful for Type 2 diabetes research.
    Formula:C24H25FN6O3
    Color and Shape:Solid
    Molecular weight:464.49

    Ref: TM-T73875

    5mg
    To inquire
    50mg
    To inquire
  • Sitagliptin fenilalanil hydrochloride

    CAS:
    Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.
    Formula:C25H25ClF6N6O2
    Color and Shape:Solid
    Molecular weight:590.95

    Ref: TM-T74592

    2mg
    85.00€
  • PF 00356231

    CAS:

    PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).

    Formula:C25H20N2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:428.5

    Ref: TM-T60071

    1mg
    185.00€
    5mg
    415.00€
    10mg
    622.00€
    25mg
    1,119.00€
    50mg
    1,679.00€
    100mg
    2,520.00€
    200mg
    3,780.00€
  • Ellipyrone A


    Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).
    Formula:C25H34O8
    Color and Shape:Solid
    Molecular weight:462.53

    Ref: TM-T75492

    5mg
    To inquire
    50mg
    To inquire