Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(137 products)
- CSF-1R(42 products)
- EGFR(581 products)
- Ephrin Receptor(25 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- HER(6 products)
- Hck(3 products)
- IGF-1R(102 products)
- PDGFR(129 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(34 products)
- Tie-2(20 products)
- Trk receptor(56 products)
- Tyrosine Kinases(8 products)
- VEGFR(242 products)
- c-Fms(108 products)
- c-Kit(117 products)
- c-Met/HGFR(144 products)
- c-RET(61 products)
Show 13 more subcategories
Found 1041 products of "Tyrosine Kinase/Adaptors"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Tilvestamab
CAS:Tilvestamab (BGB149) is a humanized monoclonal antibody targeting AXL with anti-tumor and anti-fibrotic activities, inhibiting Gas6-induced AXL activation.Purity:>95%Color and Shape:LiquidAZ7550 hydrochloride
CAS:AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Formula:C27H32ClN7O2Purity:99.65%Color and Shape:SolidMolecular weight:522.04Intetumumab
CAS:Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for xenograft tumor-bearing mice.Purity:97.6% (SDS-PAGE); 97.1% (SEC-HPLC) - 97.6% (SDS-PAGE); 97.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.56 kDaGancotamab
CAS:Gancotamab (MM-302) is a polyethylene glycolated liposome targeting HER2 with antitumor activity for the study of advanced HER2-positive breast cancer.Purity:96.7% (SDS-PAGE); 98.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 98.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:25.79 kDaErlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4Purity:98.19% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:393.44Khellin
CAS:Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.Formula:C14H12O5Purity:99.89% - 99.95%Color and Shape:Light Yellow CrystallineMolecular weight:260.24Emibetuzumab
CAS:Emibetuzumab: potent humanized MET antibody, antitumor, inhibits HGF/MET pathways, for advanced prostate cancer research.Purity:SDS-PAGE:96.2%;SEC-HPLC:98.8%Color and Shape:LiquidMolecular weight:143.74 kDa4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide
CAS:Formula:C29H31N7OPurity:98%Color and Shape:SolidMolecular weight:493.6027Ref: IN-DA00350H
5kgTo inquire10kgTo inquire1g25.00€5g33.00€10g56.00€25g61.00€100g164.00€1kg506.00€500g687.00€CSF1R-IN-1
CAS:CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.Formula:C25H20F3N5O2Purity:97.02% - 98.56%Color and Shape:SolidMolecular weight:479.45Ref: TM-T10894
1mg88.00€5mg200.00€1mL*10mM (DMSO)219.00€10mg309.00€25mg522.00€50mg747.00€100mg1,035.00€200mg1,378.00€Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C27H33N3O6SPurity:99%Color and Shape:SolidMolecular weight:527.63Ref: TM-T15675
2mg35.00€5mg52.00€1mL*10mM (DMSO)62.00€10mg66.00€25mg119.00€50mg230.00€100mg394.00€200mg532.00€Barecetamab
CAS:Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity.Purity:97.1% (SDS-PAGE); 96.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 96.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:143.86 kDaAdrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Formula:C9H11NO3·HClPurity:99.94%Color and Shape:SolidMolecular weight:217.65Ilginatinib maleate
CAS:Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable inhibitor of JAK2.
Formula:C25H24FN7O4Purity:99.74% - 99.82%Color and Shape:SolidMolecular weight:505.5HyT36
CAS:HyT36: hydrophobic tag that destabilizes fusion proteins & Her3 pseudokinase; treats cells with acute erht.Formula:C25H44ClNO3Purity:99.02%Color and Shape:SolidMolecular weight:442.07Ref: TM-T72075
1mg56.00€5mg119.00€1mL*10mM (DMSO)131.00€10mg188.00€25mg393.00€50mg628.00€100mg908.00€Lacnotuzumab
CAS:Lacnotuzumab (MCS110) is a humanized monoclonal antibody targeting CSF-1, which can be used in research on retinal diseases.Purity:>95%Color and Shape:LiquidMolecular weight:144.8 kDaLapatinib
CAS:Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.Formula:C29H26ClFN4O4SPurity:99.00% - 99.81%Color and Shape:PowderMolecular weight:581.06CSF1R-IN-2
CAS:CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).Formula:C20H20FN7O2Purity:99.29%Color and Shape:SolidMolecular weight:409.42SU 5616
CAS:SU 5616 (WAY-608241) regulates abnormal cell proliferation and modulates tyrosine kinase signaling.
Formula:C13H8ClNOSPurity:98.84%Color and Shape:SoildMolecular weight:261.73AV-412
CAS:AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).Formula:C41H44ClFN6O7S2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:851.41Ref: TM-T10419
1mg42.00€2mg55.00€5mg90.00€1mL*10mM (DMSO)129.00€10mg137.00€25mg240.00€50mg403.00€100mg582.00€Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formula:C26H29Cl2N5O3Purity:98.98% - 99.9%Color and Shape:Yellowish-Orange Or Pink To Brownish Solid Solid PowderMolecular weight:530.45Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formula:C22H28ClN7O3SPurity:99.68% - >99.99%Color and Shape:SolidMolecular weight:506.03BLU-945
CAS:BLU-945 is a reversible, potent, highly selective, and orally available epidermal growth factor receptor tyrosine kinase inhibitor (TKIs).Cost-effective and quality-assured.Formula:C28H37FN6O3SPurity:99.11% - 99.16%Color and Shape:SolidMolecular weight:556.7Ref: TM-T9754
1mg35.00€5mg75.00€10mg114.00€25mg222.00€1mL*10mM (DMSO)241.00€50mg356.00€100mg557.00€200mg790.00€1-[4-[4-[[2-[(1E)-2-[4-(Trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole
CAS:Formula:C25H23F3N4O2Purity:98%Color and Shape:SolidMolecular weight:468.4709Bucladesine sodium
CAS:Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.Formula:C18H23N5NaO8PPurity:96.56% - 99.76%Color and Shape:White PowderMolecular weight:491.37Quinoxaline, 6,7-dimethoxy-2-phenyl-
CAS:Formula:C16H14N2O2Purity:98%Color and Shape:SolidMolecular weight:266.2946Ref: IN-DA001E48
1gTo inquire1mg53.00€5mg54.00€10mg73.00€25mg107.00€50mg164.00€100mg187.00€250mg503.00€Onartuzumab
CAS:Onartuzumab (MetMAb) is a humanized monoclonal antibody targeting c-MET, with antitumor effects by blocking HGF and signal transduction.Purity:97.3%Color and Shape:LiquidMolecular weight:146.99 kDaO-Desmethyl gefitinib
CAS:O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed by CYP2D6.Formula:C21H22ClFN4O3Purity:97.17%Color and Shape:SolidMolecular weight:432.88Ref: TM-T16369
1mg52.00€5mg105.00€1mL*10mM (DMSO)114.00€10mg167.00€25mg324.00€50mg518.00€100mg742.00€Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Formula:C29H26ClFN4O4S·2C7H8O3SPurity:99.41%Color and Shape:Yellow SolidMolecular weight:925.46Petosemtamab
CAS:Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor research like HNSCC & CRC.
Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145.97 kDaGIP (3-42), human
CAS:Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.Formula:C214H324N58O63SPurity:95.73%Color and Shape:SolidMolecular weight:4749.35Erlotinib hydrochloride
CAS:Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4·HClPurity:99.78% - 99.85%Color and Shape:White Or Off-White PowderMolecular weight:429.90Gefitinib
CAS:Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations.Formula:C22H24ClFN4O3Purity:99.92% - >99.99%Color and Shape:Light-Yellow Crystalline PowderMolecular weight:446.90Allitinib
CAS:Allitinib (AST-1306) (AST-1306) has anti-cancer activity，and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1]Formula:C24H18ClFN4O2Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:448.88Ref: TM-T14336
1mg50.00€5mg105.00€1mL*10mM (DMSO)128.00€10mg172.00€25mg313.00€50mg467.00€100mg663.00€TAM-IN-2
CAS:TAM-IN-2 is an inhibitor of TAM.Formula:C31H27F2N7O3Purity:98.09% - 99.74%Color and Shape:SolidMolecular weight:583.59LCH-7749944
CAS:LCH-7749944 suppresses human gastric cancer cell growth, induces apoptosis, and inhibits PAK4 with IC50 of 14.93 μM.Formula:C20H22N4O2Purity:99.48%Color and Shape:SolidMolecular weight:350.41Ref: TM-T11826
1mg50.00€5mg103.00€1mL*10mM (DMSO)110.00€10mg156.00€25mg269.00€50mg403.00€100mg583.00€200mg785.00€Rilotumumab
CAS:Rilotumumab (AMG 102) is an HGF-targeting antibody, inhibits HGF/MET signaling, and is used for CRPC and gastric cancer research.
Purity:SDS-PAGE:95% SEC-HPLC:97.51%Color and Shape:LiquidMolecular weight:145.2 kDaGanitumab
CAS:Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.Purity:100% (SEC-HPLC) - > 95%Color and Shape:LiquidMolecular weight:145.70 kDaHck-IN-1
CAS:Hck-IN-1 selectively inhibits Nef:Hck, IC50: 2.8 μM; >20 μM for Hck alone. Potent HIV-1 Nef antagonist, IC50: 100-300 nM for HIV-1 replication.Formula:C16H11ClN6O3SPurity:99.07%Color and Shape:SolidMolecular weight:402.81Ref: TM-T11538
1mg62.00€5mg128.00€1mL*10mM (DMSO)141.00€10mg197.00€25mg323.00€50mg469.00€100mg637.00€Lapatinib ditosylate monohydrate
CAS:Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.
Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurity:98% - 99.41%Color and Shape:Colourless To Light-Yellow CrystalMolecular weight:943.47CE-245677
CAS:CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases. With a cellular IC50s of 4.7 and 1 nM.Formula:C24H22Cl2N6O3Purity:98.99% - 99.23%Color and Shape:SolidMolecular weight:513.38Ref: TM-T14921
1mg58.00€2mg82.00€5mg113.00€1mL*10mM (DMSO)129.00€10mg177.00€25mg296.00€50mg409.00€100mg605.00€c-Met inhibitor 1
CAS:c-Met inhibitor 1 is a c-Met receptor signaling pathway inhibitor, used for the treatment of cancer including glioblastoma, gastric, and pancreatic cancer.Formula:C17H14N8SPurity:98.77%Color and Shape:SolidMolecular weight:362.41Rociletinib
CAS:Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplasticFormula:C27H28F3N7O3Purity:98.52% - 99.25%Color and Shape:SolidMolecular weight:555.55Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formula:C22H26ClN7O2SPurity:99.59% - 99.86%Color and Shape:Pale-Yellow SolidMolecular weight:488.01Edicotinib
CAS:Edicotinib (JNJ-527) is a blood-brain permeable, selective CSF-1R inhibitor, with lesser inhibitory effects on KIT and FLT3.Cost-effective and quality-assured.
Formula:C27H35N5O2Purity:98.58% - 99.72%Color and Shape:SolidMolecular weight:461.6(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
CAS:Formula:C17H14N2O3Purity:98%Color and Shape:SolidMolecular weight:294.3047
![4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benz…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA00350H.webp&w=3840&q=75)
![1-[4-[4-[[2-[(1E)-2-[4-(Trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA0078T8.webp&w=3840&q=75)
