IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
Found 86 products of "IGF-1R"
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ALK inhibitor 1
CAS:<p>ALK inhibitor 1 is a selective ALK kinase inhibitor.</p>Formula:C23H28BrN7O3SPurity:98.27%Color and Shape:SolidMolecular weight:562.48AZ7550 hydrochloride
CAS:<p>AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Formula:C27H32ClN7O2Purity:99.65%Color and Shape:SolidMolecular weight:522.04GIP (3-42), human
CAS:<p>Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.</p>Formula:C214H324N58O63SPurity:95.73%Color and Shape:SolidMolecular weight:4749.35GIP (human) acetate
<p>GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.</p>Purity:98.65%Color and Shape:SoildRobatumumab
CAS:<p>Robatumumab (Sch 717454) is a fully humanized anti-IGF-1R monoclonal antibody with antitumor activity and antiproliferative activity.</p>Purity:96.9% (SDS-PAGE); 98.1% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.1% (SEC-HPLC)Color and Shape:LiquidGanitumab
CAS:<p>Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.</p>Purity:100% (SEC-HPLC) - > 95%Color and Shape:LiquidMolecular weight:145.70 kDaMSDC-0602K
CAS:<p>MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.</p>Formula:C19H16KNO5SPurity:99.42%Color and Shape:SolidMolecular weight:409.5[Pro3]-GIP (Mouse)
<p>GIP receptor blocker, 2.6μM IC50, hinders insulin release, regulates glucose in ob/ob mice, and enhances glucose tolerance.</p>Formula:C225H342N62O64SPurity:98%Color and Shape:SolidMolecular weight:4971.62Gastric Inhibitory Peptide (1-42) (porcine) TFA
<p>Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.</p>Formula:C225H342N60O66S·XCF3COOHColor and Shape:SolidMolecular weight:4975.55IGF-I (24-41)
CAS:<p>IGF-I (24-41) is a fragment of IGF-I, affecting GH activities with anabolic, antioxidant, anti-inflammatory, and cytoprotective properties.</p>Formula:C88H133N27O28Purity:98%Color and Shape:SolidMolecular weight:2017.16cis-NVP-ADW742
CAS:<p>NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.</p>Formula:C28H31N5OColor and Shape:SolidMolecular weight:453.59GIP, human
CAS:<p>Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.</p>Formula:C226H338N60O66SPurity:98%Color and Shape:SolidMolecular weight:4983.6AVE1642
<p>AVE1642 is a human IgG monoclonal antibody (mAb) that specifically targets CD221/IGF1R. It has the ability to slow the growth of tumor xenografts and extend the survival of tumor-bearing nude mice. AVE1642 is applicable in the study of advanced solid tumors. Recommended isotype control: HumanIgG1kappa, Isotype Control.</p>Color and Shape:Odour LiquidOI338
<p>OI338 is an orally available, ultralong-acting insulin analogue.</p>Formula:C260H403N65O84S6Color and Shape:SolidMolecular weight:5971.76[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)
CAS:<p>Insulin Receptor (1142-1153) binds insulin, is a substrate for its kinase, and has research/medical potential.</p>Formula:C72H110N19O33P3Purity:98%Color and Shape:SolidMolecular weight:1862.67[D-Ala2]-GIP (human)
CAS:<p>Potent GIP receptor agonist with 630 pM EC50; enhances cAMP, glucose control, insulin, cognition in diabetic/obese animals; neuroprotective in PD model.</p>Formula:C226H338N60O66SPurity:98%Color and Shape:SolidMolecular weight:4983.58IGF-1R inhibitor-2
CAS:<p>IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.</p>Formula:C24H24FN7O2Color and Shape:SolidMolecular weight:461.501GIP (1-30) amide,human
CAS:<p>GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.</p>Formula:C162H240N40O47SPurity:98%Color and Shape:SolidMolecular weight:3531.94Valanafusp alfa
CAS:<p>Valanafusp alfa (AGT-181) is a fusion protein targeting HIR and IDUA for MPS I research.</p>Color and Shape:LiquidWAY-270250
CAS:<p>WAY-270250 is an IGF-1R/SRC inhibitor.</p>Formula:C18H16N2O2Purity:99.77%Color and Shape:SoildMolecular weight:292.33ZIGIR
<p>ZIGIR enables insulin-based sorting of pure alpha and beta cells, revealing zinc(II) in human delta cell granules.</p>Formula:C39H40N6O3Purity:98.34% - 99.32%Color and Shape:SolidMolecular weight:640.77Acetyl Gastric Inhibitory Peptide (human)
CAS:<p>Acetyl Gastric Inhibitory Peptide: improved insulinotropic, antihyperglycemic, for diabetes/obesity research.</p>Formula:C228H340N60O67SColor and Shape:SolidMolecular weight:5025.6Insulin peglispro
CAS:<p>Insulin peglispro (BIL) is a basal insulin with a stable, extended activity and may offer improved blood sugar control.</p>Formula:C370H566N104O110S4Color and Shape:SolidMolecular weight:8359.32(Pro3) GIP, human
CAS:<p>(Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.</p>Formula:C226H338N60O64SColor and Shape:SolidMolecular weight:4951.53DA-JC4
CAS:<p>DA-JC4: dual GLP-1/GIP agonist, for neurological disease research and insulin pathway studies.</p>Formula:C225H346N56O65Color and Shape:SolidMolecular weight:4875.49Macupatide
CAS:<p>Macupatide is a gastric inhibitory polypeptide (GIP) receptor agonist, utilized in research related to antidiabetic applications.</p>Color and Shape:SolidGIP (1-30) amide, porcine TFA
<p>GIP (1-30) amide, porcine TFA: a full GIP receptor agonist, similar to natural GIP(1-42), stimulates insulin, mildly inhibits gastric acid.</p>Color and Shape:LiquidNBI-31772
CAS:<p>NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM).</p>Formula:C17H11NO7Purity:99.79%Color and Shape:SolidMolecular weight:341.27Teprotumumab
CAS:<p>Teprotumumab: human antibody, inhibits IGF-1R, used for thyroid eye diseases.</p>Purity:SDS-PAGE:95.2%;SEC-HPLC:99.6%Color and Shape:LiquidMolecular weight:145.62 kDaCixutumumab
CAS:<p>Cixutumumab (IMC-A12), a humanized monoclonal antibody targeting IGF-1R, exhibits high affinity and inhibits ligand-dependent receptor activation, impeding</p>Purity:98.5% (SDS-PAGE); 97.5% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:LiquidInsulin efsitora alfa
CAS:<p>Insulin efsitora alfa(LY-3209590) is an IR agonist and a fusion protein that binds a novel single-chain insulin variant to the structural domain of human IgG Fc</p>Purity:98.3% (SDS-PAGE); 98.1% (SEC-HPLC) - 98.3% (SDS-PAGE); 98.1% (SEC-HPLC)Color and Shape:LiquidLDD39
<p>LDD39, a PROTAC targeting the degradation of RET protein, effectively and persistently degrades total RET (tRET) protein in vivo and inhibits phosphorylated RET (pRET) signaling.</p>Formula:C55H59F2N11O6Color and Shape:SolidMolecular weight:1008.12TAK-778
CAS:<p>TAK-778, a derivative of ipriflavone, demonstrates the ability to stimulate bone growth in both in vitro and in vivo models.</p>Formula:C24H28NO7PSPurity:98%Color and Shape:SolidMolecular weight:505.52IGF-I (30-41)
CAS:<p>IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).</p>Formula:C51H83N19O19Purity:98%Color and Shape:SolidMolecular weight:1266.34TLK19781
CAS:<p>TLK19781 is an insulin receptor modulator.</p>Formula:C33H24Cl2N4O13S4Purity:98%Color and Shape:SolidMolecular weight:883.73Proinsulin C-peptide (human)
CAS:<p>C-peptide, a 31-amino acid, links Proinsulin A & B chains for correct folding and function.</p>Formula:C129H211N35O48Purity:98%Color and Shape:SolidMolecular weight:3020.26Insulin α-chain (1-13)
CAS:<p>Insulin alpha-chain peptide, amino acids 1-13, T cell-recognized, posttranslationally modified.</p>Formula:C66H118N20O22S3Purity:98%Color and Shape:SolidMolecular weight:1639.96PQ401
CAS:<p>PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).</p>Formula:C18H16ClN3O2Purity:99.77%Color and Shape:SolidMolecular weight:341.79HNMPA
CAS:<p>HNMPA blocks insulin receptor kinase, halting autophosphorylation; no impact on cAMP protein kinase or PKC.</p>Formula:C11H11O4PPurity:99.18%Color and Shape:SolidMolecular weight:238.18IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)
<p>The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis</p>Color and Shape:Lyophilized PowderMolecular weight:80.59 kDa (alpha subunit) and 19.28 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 48-58 kDa (beta subunit) and 100-115 kDa (alpha subunit) and 130-150 kDa based on Tris-Bis PAGE result.IGF1R/CD221 Protein, Mouse, Recombinant (His)
<p>IGF1R/CD221 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Purity:> 95% as determined by Bis-Tris PAGE > 90% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 90% as determined by HPLCColor and Shape:Lyophilized PowderMolecular weight:80.72+23.0 kDa (predicted); 110-140 kDa and 50-65 kDa, corresponding to the α subunit and β subunit respectively (reducing condition, due to glycosylation)IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
<p>The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis</p>Color and Shape:Lyophilized PowderMolecular weight:105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa (alpha subunit) and 52-55 kDa (beta subunit) based on Tris-Bis PAGE result.HNMPA-(AM)3
CAS:<p>HNMPA-(AM)3 抑制 ERK 磷酸化的激活以及促促胸腺激素 (PTTH) 刺激蜕皮类固醇产生。 此外，HNMPA-(AM)3 对蜕皮类固醇产生 (IC50=14.2 μM) 和胰岛素受体活性 (IC50=14.2 μM 和 200 μM，在蚊子和哺乳动物中分别) 具有抑制作用。</p>Formula:C20H23O10PPurity:97.22%Color and Shape:SolidMolecular weight:454.36IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
<p>The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis</p>Color and Shape:Lyophilized PowderMolecular weight:105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa(alpha subunit) and 52-55 kDa(beta subunit) based on Tris-Bis PAGE result.Ceritinib
CAS:<p>Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C28H36ClN5O3SPurity:98.52% - 99.77%Color and Shape:SolidMolecular weight:558.14MID-1
CAS:<p>MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.</p>Formula:C12H11N3O4SPurity:99.39%Color and Shape:SolidMolecular weight:293.3AG1024
CAS:<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Formula:C14H13BrN2OPurity:98% - 99.37%Color and Shape:SolidMolecular weight:305.17NVP-AEW541
CAS:<p>NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based</p>Formula:C27H29N5OPurity:98.7% - 99.86%Color and Shape:SolidMolecular weight:439.55BMS-536924
CAS:<p>BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for</p>Formula:C25H26ClN5O3Purity:99.02%Color and Shape:SolidMolecular weight:479.96Picropodophyllin
CAS:<p>Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM, not affecting other growth factor receptors.</p>Formula:C22H22O8Purity:98.88% - 99.62%Color and Shape:SolidMolecular weight:414.41NVP-TAE 226
CAS:<p>NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.</p>Formula:C23H25ClN6O3Purity:98.07% - 98.78%Color and Shape:SolidMolecular weight:468.94MAZ51
CAS:<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Formula:C21H18N2OPurity:98.53%Color and Shape:SolidMolecular weight:314.38XL228
CAS:<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Ceritinib dihydrochloride
CAS:<p>Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase with antitumour effect.</p>Formula:C28H38Cl3N5O3SPurity:99.85% - 99.99%Color and Shape:SolidMolecular weight:631.06NT157
CAS:<p>NT157, a small tyrphostin, inhibits IRS, IGF-1R, and STAT3 in TME, reducing cancer cell survival.</p>Formula:C16H14BrNO5SPurity:99.64%Color and Shape:SolidMolecular weight:412.26Ginsenoside Rg5
CAS:<p>Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.</p>Formula:C42H70O12Purity:98% - 99.65%Color and Shape:SolidMolecular weight:767Insulin(cattle)
CAS:<p>Insulin(cattle) is a peptide hormone that promotes glycogen synthesis. Insulin) has hypoglycemic activity. Cost-effective and quality-assured.</p>Formula:C254H377N65O75S6Purity:98%Color and Shape:SolidMolecular weight:5733.49GSK1838705A
CAS:<p>GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.</p>Formula:C27H29FN8O3Purity:98.89% - >99.99%Color and Shape:SolidMolecular weight:532.57AZ7550
CAS:<p>AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Formula:C27H31N7O2Purity:97.07% - 99.75%Color and Shape:SolidMolecular weight:485.58NVP-ADW742
CAS:<p>NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl</p>Formula:C28H31N5OPurity:96.14% - 98.70%Color and Shape:SolidMolecular weight:453.58NBI-31772 hydrate
<p>NBI-31772 hydrate blocks IGF and IGFBPs binding, freeing IGF-I with Ki 1-24 nM; it has anxiolytic and antidepressant effects.</p>Formula:C17H13NO8Color and Shape:SolidMolecular weight:372.82Linsitinib
CAS:<p>OSI-906 (Linsitinib) is an oral inhibitor of IGF-1R with anti-cancer properties, potentially halting tumor growth and inducing cell death.</p>Formula:C26H23N5OPurity:99.71% - ≥95%Color and Shape:SolidMolecular weight:421.49AZD-3463
CAS:<p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>Formula:C24H25ClN6OPurity:99.13%Color and Shape:SolidMolecular weight:448.95BRD7552
CAS:<p>BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells.</p>Formula:C33H33N3O15Purity:>99.99% - ≥98%Color and Shape:SolidMolecular weight:711.63PQ401 hydrochloride (196868-63-0(free base))
<p>PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.</p>Formula:C18H17Cl2N3O2Purity:99.86%Color and Shape:SolidMolecular weight:378.25MSDC 0160
CAS:<p>MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.</p>Formula:C19H18N2O4SPurity:98.11% - 99.53%Color and Shape:SolidMolecular weight:370.42Indirubin Derivative E804
CAS:<p>Indirubin Derivative E804 is a potent insulin-like growth factor type 1 receptor (IGF1R) inhibitor with potential antitumor activity.</p>Formula:C20H19N3O4Purity:98.54%Color and Shape:SolidMolecular weight:365.38GSK1904529A
CAS:<p>GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .</p>Formula:C44H47F2N9O5SPurity:98.2% - 99.38%Color and Shape:SolidMolecular weight:851.96Dusigitumab
CAS:<p>Dusigitumab (MEDI573) is a fully humanised monoclonal antibody targeting IGF1/IGF2, inhibiting IGF1/IGF2-induced IGF-1R phosphorylation.</p>Purity:95% - 95%Color and Shape:LiquidFigitumumab
CAS:<p>Figitumumab is a potent anti-IGF1R mAb (IC50=1.8 nM) showing promise in advanced lung squamous cell carcinoma.</p>Purity:95%Color and Shape:LiquidVeligrotug
CAS:<p>Veligrotug is an IV anti-IGF-1R antibody for thyroid eye disease, reducing diplopia and orbital inflammation, supporting autoimmune ophthalmopathy research.</p>Purity:95% - 95%Color and Shape:LiquidAnti-IGFBP2 Antibody (M14)
<p>Anti-IGFBP2 Antibody (M14) is a human monoclonal antibody inhibitor that binds with high affinity to IGFBP2 and prevents its interaction with IGF1. Additionally, Anti-IGFBP2 Antibody (M14) can inhibit the recruitment of human endothelial cells, thereby obstructing tumor progression in human metastatic cancers.</p>Color and Shape:Odour LiquidS961
CAS:<p>S961: High-affinity IR antagonist; IC50: HIR-A 0.048 nM, HIR-B 0.027 nM, HIGF-IR 630 nM.</p>Formula:C211H297N55O71S2Purity:98%Color and Shape:SolidMolecular weight:4804.13BMS-754807
CAS:<p>BMS-754807 is an oral IGF-1R/InsR inhibitor with potential anti-cancer properties.</p>Formula:C23H24FN9OPurity:99.69% - 99.94%Color and Shape:SolidMolecular weight:461.49D-(+)-Sorbose
CAS:<p>D-(+)-Sorbose, an enantiomer inhibiting disaccharidase, lowers glucose and insulin post-meal in rats, possibly preventing diabetes.</p>Formula:C6H12O6Color and Shape:SolidMolecular weight:180.16BM-131246
CAS:<p>BM-131246 is an orally available and antidiabetic active thiazolidinedione derivative for the study of diabetes.</p>Formula:C22H20N2O4SPurity:>99.99%Color and Shape:SolidMolecular weight:408.47AZ12253801
CAS:<p>AZ12253801 is a type 1 insulin-like growth factor receptor (IGF-1R) inhibitor.</p>Formula:C21H22N8OPurity:98%Color and Shape:SolidMolecular weight:402.45KU14R
CAS:<p>KU14R is a new I(3)-R antagonist, which selectively blocks the insulin secretory response to imidazolines.</p>Formula:C13H14N2OPurity:98%Color and Shape:White SolidMolecular weight:214.26I-OMe-Tyrphostin AG 538
CAS:<p>I-OMe-Tyrphostin AG 538: IGF-1R & PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, cytotoxic in nutrient-poor PANC1 cells.</p>Formula:C17H12INO5Purity:98.23%Color and Shape:SolidMolecular weight:437.19Protonstatin-1
CAS:<p>Protonstatin-1: treats hypoglycemia & Alzheimer's, inhibits IGFIR kinase, used in cancer studies.</p>Formula:C8H5NO2S2Purity:99.77%Color and Shape:SolidMolecular weight:211.26NT219
CAS:<p>NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3 that enhances the aggregation of misfolded prion proteins NT219 Effects.</p>Formula:C16H14BrNO5SPurity:98.06% - 99.72%Color and Shape:SolidMolecular weight:412.26BMS-695735
CAS:<p>BMS-695735: benzimidazole, inhibits IGF-1 receptor, broad antitumor effects, affects CYP3A4, low solubility, binds plasma proteins.</p>Formula:C26H31ClFN7OColor and Shape:SolidMolecular weight:512.02Tyrphostin AG 538
CAS:<p>Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.</p>Formula:C16H11NO5Purity:98.75%Color and Shape:SoildMolecular weight:297.26CL-A3-7
CAS:<p>CL-A3-7 is a viral-cell fusion inhibitor targeting the RSVF protein. It functions by blocking the interaction between the virus and the host's IGF1R, effectively inhibiting the infection of both wild-type and K394R mutant strains of RSV. This compound is suitable for use in antiviral drug development and resistance studies related to RSV.</p>Formula:C24H22Br2F2N2O3Color and Shape:SolidMolecular weight:584.25IGF-1R inhibitor-4
CAS:<p>IGF-1Rinhibitor-4 (compound 22) is a potent inhibitor of IGF-1R, demonstrating an inhibition rate of 63% at a concentration of 10 μM. This compound plays a significant role in cancer research.</p>Formula:C13H15ClN4OColor and Shape:SolidMolecular weight:278.737AGL-2263
CAS:<p>AGL-2263 is a blocker of insulin receptor (IR)</p>Formula:C17H10N2O5Color and Shape:SolidMolecular weight:322.27
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