Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1534 products of "Cytoskeletal Signaling"
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N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formula:C28H29N7OPurity:98.60%Color and Shape:Off-White To Pale-Yellow SolidMolecular weight:479.58Ref: TM-T11641
1mg87.00€5mg166.00€10mg303.00€25mg512.00€50mg737.00€100mg1,018.00€1mL*10mM (DMSO)170.00€BNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formula:C20H20O7Purity:96.57%Color and Shape:SolidMolecular weight:372.37Ref: TM-T14694
1mg79.00€5mg152.00€10mg215.00€25mg351.00€50mg494.00€100mg665.00€200mg893.00€1mL*10mM (DMSO)167.00€CK-666
CAS:CK-666 inhibits Arp2/3 complex, blocking Arp2/3 activation and actin filament formation.Formula:C18H17FN2OPurity:99.93%Color and Shape:SolidMolecular weight:296.34Ref: TM-T10826
1mg38.00€5mg82.00€10mg133.00€25mg266.00€50mg515.00€100mg715.00€200mg895.00€1mL*10mM (DMSO)90.00€Bersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:144.22 kDaRecilisib
CAS:Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.Formula:C16H13ClO4SPurity:98.85% - 98.96%Color and Shape:SolidMolecular weight:336.79Ref: TM-T13862
1mg43.00€2mg56.00€5mg93.00€10mg113.00€25mg177.00€50mg295.00€100mg477.00€200mg677.00€1mL*10mM (DMSO)100.00€NMS-P715
CAS:NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Formula:C35H39F3N8O3Purity:99.84%Color and Shape:SolidMolecular weight:676.73Talquetamab
CAS:Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.Color and Shape:LiquidMolecular weight:144.59 kDaSpiperone
CAS:Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.Formula:C23H26FN3O2Purity:99.34% - 99.91%Color and Shape:SolidMolecular weight:395.47BML-286
CAS:BML-286 is a WNT pathway modulator with potential anticancer activity and induces β-catenin- and TCF- dependent transcriptional activity.Formula:C22H18N2O4Purity:98.44%Color and Shape:SolidMolecular weight:374.39Arimoclomol maleate
CAS:Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Formula:C18H24ClN3O7Purity:99.44% - 99.98%Color and Shape:SolidMolecular weight:429.85AKE-72
CAS:AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.Formula:C30H29F3N6OPurity:98.3%Color and Shape:SoildMolecular weight:546.59Ref: TM-T80676
1mg88.00€2mg129.00€5mg212.00€10mg310.00€25mg479.00€50mg642.00€100mg880.00€200mg1,161.00€Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formula:C26H29Cl2N5O3Purity:98.98% - 99.9%Color and Shape:Yellowish-Orange Or Pink To Brownish Solid Solid PowderMolecular weight:530.45Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaDelcasertib
CAS:Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).Formula:C120H199N45O34S2Purity:99.96%Color and Shape:SolidMolecular weight:2880.28Ref: TM-T11740
1mg192.00€5mg485.00€10mg700.00€25mg1,063.00€50mg1,459.00€100mg1,963.00€1mL*10mM (DMSO)1,603.00€Teplizumab
CAS:Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Purity:SDS-PAGE:95.8%;SEC-HPLC:99.7%Color and Shape:LiquidMolecular weight:145.79 kDaGlofitamab
CAS:Glofitamab (RO7082859), a bivalent antibody, targets CD20 on B-cells to aid T cell attack in relapsed/refractory lymphomas.
Purity:SDS-PAGE:98.2%;SEC-HPLC:98.0%Color and Shape:LiquidMolecular weight:170.37 kDaOrbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormula:C19H24F3N5O6Purity:97.21% - 98.72%Color and Shape:SolidMolecular weight:475.42SGC-AAK1-1
CAS:SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.
Formula:C21H25N5O3SPurity:99.68%Color and Shape:SolidMolecular weight:427.52ML-9
CAS:ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.Formula:C15H18Cl2N2O2SPurity:99.69%Color and Shape:Crystalline SolidMolecular weight:361.29Col003
CAS:Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Formula:C14H11NO4Purity:99.03% - 99.96%Color and Shape:SolidMolecular weight:257.24Ref: TM-T10860
2mg47.00€5mg70.00€10mg107.00€25mg216.00€50mg350.00€100mg542.00€200mg778.00€500mg1,169.00€1mL*10mM (DMSO)70.00€Abrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Purity:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Color and Shape:LiquidMolecular weight:143.80 kDaLXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Formula:C25H25F3N4O4Purity:98.3% - 99.92%Color and Shape:SolidMolecular weight:502.49Ref: TM-T11898
1mg52.00€5mg122.00€10mg185.00€25mg363.00€50mg567.00€100mg690.00€200mg948.00€500mg1,444.00€1mL*10mM (DMSO)135.00€Nilotinib
CAS:Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.Formula:C28H22F3N7OPurity:99.89% - >99.99%Color and Shape:Off-White SolidMolecular weight:529.52AC 7739
CAS:AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.Formula:C18H22ClNO4Purity:99.38% - 99.55%Color and Shape:SoildMolecular weight:351.83PKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Purity:95.42%Color and Shape:SoildMitoxantrone dihydrochloride
CAS:Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Formula:C22H30Cl2N4O6Purity:97.05% - >99.99%Color and Shape:Blue-Black Solid From Water Ethanol SolidMolecular weight:517.4Vantictumab
CAS:Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Purity:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:142.69 kDaZagotenemab
CAS:Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Purity:> 95% - >95.0% (SDS-PAGE)Color and Shape:LiquidMolecular weight:145.3 kDaMps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formula:C26H31N7O4SPurity:99.25%Color and Shape:SolidMolecular weight:537.63Ref: TM-T16130
2mg34.00€5mg54.00€10mg87.00€25mg149.00€50mg255.00€100mg384.00€200mg538.00€1mL*10mM (DMSO)64.00€Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formula:C17H20ClNOPurity:99.32% - 99.85%Color and Shape:SolidMolecular weight:289.8ATN-161 acetate
CAS:ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Formula:C25H39N9O10SPurity:98.27%Color and Shape:SoildMolecular weight:657.7Ref: TM-T10398L
1mg190.00€5mg471.00€10mg663.00€25mg1,036.00€50mg1,429.00€100mg1,830.00€200mg2,498.00€TINK-IN-1
CAS:TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.Formula:C24H24N4O3Purity:99.4%Color and Shape:SoildMolecular weight:416.47Ref: TM-T77660
1mg39.00€2mg50.00€5mg82.00€10mg120.00€25mg236.00€50mg353.00€100mg517.00€500mg1,099.00€ATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formula:C25H36F3N9O10SPurity:98% - 99.98%Color and Shape:SolidMolecular weight:711.67Fluorofenidone
CAS:Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.
Formula:C12H10FNOPurity:99.85%Color and Shape:SolidMolecular weight:203.21N-Desmethyltamoxifen hydrochloride
CAS:N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Formula:C25H28ClNOPurity:99.15%Color and Shape:SolidMolecular weight:393.95Meclofenamic acid sodium
CAS:Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.Formula:C14H10Cl2NNaO2Purity:98% - 98.96%Color and Shape:SolidMolecular weight:318.14Larazotide acetate
CAS:Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.Formula:C34H59N9O12Purity:95.53% - 99.425%Color and Shape:SolidMolecular weight:785.89Darifenacin hydrobromide
CAS:Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.Formula:C28H31BrN2O2Purity:99.75% - >99.99%Color and Shape:SolidMolecular weight:505.457-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Formula:C10H12N2O5SPurity:91.05%Color and Shape:White Solid PowderMolecular weight:272.28Verubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormula:C17H18ClN3OPurity:98.29% - 99.77%Color and Shape:SolidMolecular weight:315.8Ref: TM-T13298
5mg52.00€10mg73.00€25mg138.00€50mg200.00€100mg284.00€200mg411.00€1mL*10mM (DMSO)52.00€CWP232228
CAS:CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Formula:C33H34N7Na2O7PPurity:98.87%Color and Shape:SolidMolecular weight:717.63JW74
CAS:JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).Formula:C24H20N6O2SPurity:95.00%Color and Shape:SolidMolecular weight:456.52Bepranemab
CAS:Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.Purity:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.92 kDaAbituzumab
CAS:Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Purity:>95%Color and Shape:LiquidMolecular weight:144.58 kDaDonanemab
CAS:Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.Purity:95%Color and Shape:LiquidMolecular weight:145.36 kDa2,3-Butanedione 2-Monoxime
CAS:2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.Formula:C4H7NO2Purity:98.62%Color and Shape:Physical Description Cream-Colored Powder (Ntp 1992)Molecular weight:101.1GRP78-IN-3
CAS:GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.Formula:C17H18N4O2SPurity:99.49%Color and Shape:SoildMolecular weight:342.42Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Formula:C26H18ClN3O2Purity:98.40%Color and Shape:SolidMolecular weight:439.89BOS-172722
CAS:BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Formula:C24H30N8OPurity:99.37%Color and Shape:SolidMolecular weight:446.55Elarofiban TFA
CAS:Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.Formula:C26H34F6N4O8Purity:99.08%Color and Shape:SoildMolecular weight:644.56IPI-493
CAS:IPI-493 is a bioactive chemical.Formula:C28H39N3O8Purity:>99.99%Color and Shape:SolidMolecular weight:545.62Akt3 degrader 1
CAS:Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.Formula:C53H72N8O4Purity:98.12% - 99.02%Color and Shape:SolidMolecular weight:885.19Ethoxyquin
CAS:Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.Formula:C14H19NOPurity:97.15% - 98.73%Color and Shape:Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Molecular weight:217.31Lyn-IN-1
CAS:Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and LynFormula:C30H31F3N8OPurity:97% - 98.02%Color and Shape:SolidMolecular weight:576.62Ref: TM-T11916
1mg38.00€2mg50.00€5mg79.00€10mg117.00€25mg236.00€50mg371.00€100mg530.00€200mg770.00€1mL*10mM (DMSO)92.00€Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Formula:C17H31N7O10Purity:98.14%Color and Shape:SolidMolecular weight:493.47ADH-1 trifluoroacetate
CAS:ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.Formula:C24H35F3N8O8S2Purity:90.08% - 99.98%Color and Shape:SolidMolecular weight:684.71Ref: TM-T1608
2mg42.00€5mg62.00€10mg89.00€25mg167.00€50mg227.00€100mg339.00€200mg482.00€1mL*10mM (DMSO)89.00€CC-99677
CAS:CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.Formula:C22H20ClN5O3SPurity:99.59%Color and Shape:SolidMolecular weight:469.94Foralumab
CAS:Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.Purity:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.59 kDaImatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,
Formula:C29H31N7O·CH4SO3Purity:98% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:589.71Xentuzumab
CAS:Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits AKT activation and can be used to study solid tumours.Purity:95.21% - >95.0% (SDS-PAGE); >95.0% (SEC-HPLC)Color and Shape:LiquidMolecular weight:143.7 kDaKY1220
CAS:KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.Formula:C14H10N4O3SPurity:99.9%Color and Shape:SolidMolecular weight:314.32Ref: TM-T15677
2mg34.00€5mg66.00€10mg101.00€25mg200.00€50mg319.00€100mg515.00€200mg702.00€1mL*10mM (DMSO)70.00€NVS-PAK1-1
CAS:NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Formula:C23H25ClF3N5OPurity:99.35%Color and Shape:SolidMolecular weight:479.93IMAB027
CAS:Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.
Purity:97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:LiquidRWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Formula:C18H17F3N4O2SPurity:99.09%Color and Shape:SolidMolecular weight:410.41Ref: TM-T12783
1mg120.00€5mg295.00€10mg447.00€25mg707.00€50mg964.00€100mg1,243.00€200mg1,693.00€1mL*10mM (DMSO)326.00€CMPD101
CAS:CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formula:C24H21F3N6OPurity:99.01% - 99.04%Color and Shape:SolidMolecular weight:466.46Danicamtiv
CAS:Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.Formula:C16H20F3N5O4SPurity:99.38%Color and Shape:SolidMolecular weight:435.42Ref: TM-T15050
1mg129.00€5mg260.00€10mg430.00€25mg710.00€50mg973.00€100mg1,333.00€1mL*10mM (DMSO)286.00€Fluocinolone (Acetonide)
CAS:Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Formula:C24H30F2O6Purity:99.29% - 99.82%Color and Shape:Crystals From Acetone & Hexane SolidMolecular weight:452.49(+)-Blebbistatin
CAS:(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.
Formula:C18H16N2O2Purity:99.88%Color and Shape:SolidMolecular weight:292.33Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formula:C22H26ClN7O2SPurity:99.59% - 99.86%Color and Shape:Pale-Yellow SolidMolecular weight:488.01AS1949490
CAS:AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.Formula:C20H18ClNO2SPurity:99.94%Color and Shape:SolidMolecular weight:371.88Ref: TM-T14327
1mg38.00€2mg50.00€5mg84.00€10mg119.00€25mg236.00€50mg380.00€100mg555.00€1mL*10mM (DMSO)93.00€Adropin (34-76) (human, mouse, rat)
CAS:Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance. Cost-effective and quality-assured.Formula:C190H293N55O68S2Purity:94.23% - 99.95%Color and Shape:SolidMolecular weight:4499.82Cibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Purity:SDS-PAGE:99.1%;SEC-HPLC:96.5%Color and Shape:LiquidMolecular weight:191.1 kDaDasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formula:C22H28ClN7O3SPurity:99.68% - >99.99%Color and Shape:SolidMolecular weight:506.03Otelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Purity:>95%Color and Shape:LiquidTubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Formula:C20H14ClNO2SPurity:99.05%Color and Shape:SolidMolecular weight:367.85A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formula:C12H14Cl2N2O2SPurity:99.32%Color and Shape:SolidMolecular weight:321.22Ref: TM-T14069
1mg34.00€5mg63.00€10mg90.00€25mg161.00€50mg260.00€100mg416.00€500mg888.00€1mL*10mM (DMSO)95.00€Paprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formula:C16H11N3Purity:99.91%Color and Shape:SolidMolecular weight:245.28Ref: TM-T12359
5mg46.00€10mg58.00€25mg92.00€50mg160.00€100mg236.00€200mg353.00€500mg580.00€1mL*10mM (DMSO)49.00€Pamidronate Disodium
CAS:Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.Formula:C3H9NNa2O7P2Purity:99.86% - 99.93%Color and Shape:White CrystalsMolecular weight:279.03GNE 2861
CAS:GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.Formula:C22H26N6O2Purity:97.03%Color and Shape:SolidMolecular weight:406.48Ref: TM-T16429
1mg40.00€2mg52.00€5mg82.00€10mg124.00€25mg245.00€50mg409.00€100mg605.00€1mL*10mM (DMSO)87.00€Bisindolylmaleimide VIII acetate
CAS:Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.Formula:C26H26N4O4Purity:99.27%Color and Shape:SolidMolecular weight:458.51Coronaridine
CAS:Coronaridine is a useful organic compound for research related to life sciences. The catalog number is T124824 and the CAS number is 467-77-6.
Formula:C21H26N2O2Color and Shape:SolidMolecular weight:338.451PKCiota-IN-2
CAS:PKCiota-IN-2 selectively inhibits PKC-ι (IC50=2.8nM) and also blocks PKC-α, ε (IC50s=71nM, 350nM).Formula:C24H21N5OPurity:98.86%Color and Shape:SolidMolecular weight:395.46Ref: TM-T9863
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€1mL*10mM (DMSO)279.00€Tubulin polymerization-IN-46
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breastFormula:C22H25NO6Color and Shape:SolidMolecular weight:399.44Zolbetuximab
CAS:Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2 for certain gastrointestinal and pancreatic cancers.
Purity:95.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97%+Color and Shape:LiquidMolecular weight:147.09 kDaBisindolylmaleimide III
CAS:Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6Formula:C23H20N4O2Purity:97.2%Color and Shape:SolidMolecular weight:384.43trans-Dehydrocurvularin
CAS:trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.Formula:C16H18O5Color and Shape:SolidMolecular weight:290.315Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,Formula:C16H13ClN6SColor and Shape:SolidMolecular weight:356.83Mps1-IN-6
Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].Formula:C35H39N9O3Color and Shape:SolidMolecular weight:633.74Abl Cytosolic Substrate
CAS:Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ).Formula:C64H101N15O16Purity:98%Color and Shape:SolidMolecular weight:1336.58Bimosiamose
CAS:Bimosiamose has anti-inflammatory effects[1].Formula:C46H54O16Purity:98%Color and Shape:SolidMolecular weight:862.91MK2-IN-5
CAS:MK2-IN-5, a pseudosubstrate of Mk2 with an inhibition constant (K_i) of 8 μM, selectively targets the protein interaction domain of the MAPK pathway andFormula:C61H113N21O16Purity:98%Color and Shape:SolidMolecular weight:1396.68Ceratamine A
CAS:Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.
Formula:C17H16Br2N4O2Purity:98%Color and Shape:SolidMolecular weight:468.14SNIPER(ABL)-015
SNIPER(ABL)-015, a compound that conjugates GNF5 (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 5Formula:C58H70F3N9O9Purity:98%Color and Shape:SolidMolecular weight:1094.23Myosin V-IN-1
CAS:Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.
Formula:C29H26N6O3SPurity:98.64% - 98.64%Color and Shape:SolidMolecular weight:538.62MS98
CAS:MS98, a specific PROTAC AKT degrader, depletes T-AKT with DC50 of 78 nM; binds AKT1, AKT2, AKT3 with Kds of 4, 140, 8.1 nM.
Formula:C58H81ClN10O7SColor and Shape:SolidMolecular weight:1097.86Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formula:C21H29N5O6Purity:99.57%Color and Shape:SolidMolecular weight:447.48Gamitrinib TPP
CAS:Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.Formula:C52H65N3O8PPurity:98%Color and Shape:SolidMolecular weight:891.0786BrCaQ-C10-TPP
6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.Formula:C45H47Br2N2O3PColor and Shape:SolidMolecular weight:854.65SNIPER(ABL)-050
SNIPER(ABL)-050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker.Formula:C68H84N12O9Purity:98%Color and Shape:SolidMolecular weight:1213.47PDS-0330
CAS:PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.Formula:C25H17N3O2SPurity:98.81%Color and Shape:SoildMolecular weight:423.49
