Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65630 products of "Quinazoline and Quinoline Derivatives"
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Desmethyl Nintedanib Carboxylic Acid (Nintedanib Impurity A)
Controlled Product<p>Applications Desmethyl Nintedanib Carboxylic Acid is an impurity of Intedanib (I666650), which is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases. it is an indolinone as triple angiokinase inhibitors and an antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Formula:C29H29N5O5Color and Shape:NeatMolecular weight:527.571-(4-(4-(tert-Butyl)phenyl)-4-hydroxybutyl)piperidine-4-carboxylic Acid
Controlled ProductFormula:C20H31NO3Color and Shape:NeatMolecular weight:333.4653-[(Methylamino)sulfonyl]-2-thiophenecarboxylic Acid
CAS:Controlled ProductFormula:C6H7NO4S2Color and Shape:Off-WhiteMolecular weight:221.254'-Desmethoxy-4'-chloro Moxonidine
CAS:Controlled Product<p>Impurity Moxonidine<br>Applications 4'-Desmethoxy-4'-chloro Moxonidine is an impurity of moxonidine.<br>References Milovanovic, S., et al.: J. Pharm. Biomed. Anal., 59, 151 (2012); Filipic, S., et al.: J. Liquid Chromatogr. Related Technol., 38, 1121 (2015)<br></p>Formula:C8H9Cl2N5Color and Shape:NeatMolecular weight:246.10N-Ethyl-3-buteno-o-toluidide
CAS:Controlled ProductFormula:C13H17NOColor and Shape:NeatMolecular weight:203.28Camostat Mesylate
CAS:Controlled ProductFormula:C20H22N4O5·CH4O3SColor and Shape:NeatMolecular weight:494.522',6'-Dichloroacetanilide
CAS:Controlled ProductFormula:C8H7Cl2NOColor and Shape:NeatMolecular weight:204.051-Hydroxy-3-nitrodeamino Fingolimod
CAS:Controlled Product<p>Applications An impurity of Fingolimod (F805000, HCl salt), a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs.<br>References Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),<br></p>Formula:C19H31NO5Color and Shape:NeatMolecular weight:353.455-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An intermediate of 5-Fluoro Risperidone (F595925).<br>References Strupczewski, J.T., et al.: J. Med. Chem., 28, 761 (1985),<br></p>Formula:C12H13FN2O·ClHColor and Shape:NeatMolecular weight:256.705,7-Difluorochroman-4-one
CAS:Controlled ProductFormula:C9H6F2O2Color and Shape:NeatMolecular weight:184.14rac-Sitagliptin (S)-Maleate Adduct (mixture of diastereomers)
Controlled ProductFormula:C20H19F6N5O5Color and Shape:NeatMolecular weight:523.39Lodoxamide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Lodoxamide is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability.<br>References Ciprandi, G., et al.: Allergy, 51(12), 946-951 (1996); Bayer, Atilla., et al.: Ophthalmologica, 217(2), 119-123 (2003)<br></p>Formula:C11H6ClN3O6Color and Shape:NeatMolecular weight:311.63(Z)-4-(2,4-Difluorobenzoyl)piperidine Oxime
CAS:Controlled Product<p>Applications Intermediate in the preparation of Risperidone (R525000) and it’s derivatives.<br></p>Formula:C12H14F2N2OColor and Shape:NeatMolecular weight:240.24923-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride
CAS:<p>Applications Sitagliptin intermediate.<br>References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982), Sarges, R., et al.: J. Med. Chem., 33, 2240 (1990), Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (2002),<br></p>Formula:C6H7F3N4·ClHColor and Shape:WhiteMolecular weight:228.60Flumequine Ethyl Ester
CAS:Controlled Product<p>Applications Flumequine Ethyl Ester is an impurity of Flumequine (F445000), a quinolone antibacterial.<br>References Stilwell, G., et al.: Antimicrob. Agents Chemother., 7, 483 (1975), Rohlfing, S.R., et al.: J. Antimicrob. Chemother., 3, 615 (1977),<br></p>Formula:C16H16FNO3Color and Shape:NeatMolecular weight:289.30N-Methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
CAS:Controlled Product<p>Applications N-Methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide is an impurity of Axitinib (A794650), a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),<br></p>Formula:C22H18N4OSColor and Shape:NeatMolecular weight:386.4695Pamapimod
CAS:Controlled Product<p>Applications A selective inhibitor of the α-isoform of p38 MAP kinase. It is used in in treatment of patient with rheumatoid arthritis. Pamapimod was tolerable but not effective as Methotrexate.<br>References Guan, Z., et al.: J. Biol. Chem., 273, 12901 (1998), Lee, J., et al.: Pharmacol. Ther., 82, 389 (1999), Korb, A., et al.: Arthritis Rheum., 54, 2745 (2006),<br></p>Formula:C19H20F2N4O4Color and Shape:WhiteMolecular weight:406.38N-[(2Z)-Piperazin-2-ylidene]-2,2,2-trifluoroacetohydrazide
CAS:Controlled Product<p>Applications Sitagliptin intermediate.<br>References Sarges, R, et al.: J. Med. Chem., 33, 2240 (1990),<br></p>Formula:C6H9F3N4OColor and Shape:NeatMolecular weight:210.164-(2-Pyridinyl)benzaldehyde
CAS:Controlled Product<p>Impurity Atazanavir Impurity (Pyridinyl Benzaldehyde)<br>Applications Reactive metabolite of atazanavir. Atazanavir Impurity; Pyridinyl Benzaldehyde impurity<br>References F. Li et al., Drug Metabolism and Disposition 39, 294 (2011)<br></p>Formula:C12H9NOColor and Shape:NeatMolecular weight:183.21N-[[N-Methyl-N-[(2-isopropyl]-4-thiazolyl)methyl)amino]carbonyl-L-valine Carboxylic Acid
CAS:Controlled Product<p>Impurity Ritonavir EP Impurity A<br>Applications N-[[N-Methyl-N-[(2-isopropyl]-4-thiazolyl)methyl)amino]carbonyl-L-valine Carboxylic Acid (Ritonavir EP Impurity A) is an intermediate in the synthesis of Ritonavir.<br>References Hamada, Y., et al.: Bioorg. Med. Chem., 10, 4155 (2002),<br></p>Formula:C14H23N3O3SColor and Shape:NeatMolecular weight:313.427,7'-[1,4-Piperazinediylbis(4,1-butanediyloxy)]bis-2(1H)-quinolinone
CAS:Controlled ProductFormula:C30H36N4O4Color and Shape:NeatMolecular weight:516.634-Isobutylamino-3-aminoquinoline
CAS:Controlled Product<p>Applications 4-Isobutylamino-3-aminoquinoline is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998); Gerster, J. et al.: J. Med. Chem., 48, 3481 (2005);<br></p>Formula:C13H17N3Color and Shape:NeatMolecular weight:215.29Dasatinib Carboxylic Acid
CAS:Controlled Product<p>Applications An oxidative metabolite of Dasatinib (M6 metabolite); used in the treatment of cancers and immune diseases. It is a COVID19-related research product.<br>References Jaworski, T., et al.: Xenobiotica, 21, 1451 (1991), Shah, N., et al.: Science, 305, 399 (2004), O'Hare, T., et al.: Cancer Res., 65, 4500 (2005), Das, J., et al.: J. Med. Chem., 49, 6819 (2006), Christopher, L., et al.: Drug Metab. Dispos., 36, 1341 (2008),<br></p>Formula:C22H24ClN7O3SColor and Shape:Light YellowMolecular weight:501.99(R)-Ofloxacin-d3
CAS:Controlled Product<p>Applications A labelled fluorinated quinolone antibacterial. An enantiomer of Levofloxacin (L360000).<br>References Hwangbo, H.J. et al.: Eur. J. Pharmac. Sci., 18, 197 (203); Gascon, A.R. et al.: J. Clin. Pharmacol, 40, 869 (2000); Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990);<br></p>Formula:C182H3H17FN3O4Color and Shape:NeatMolecular weight:364.39Desacetyl Diltiazem-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Diltiazem (D460620).<br></p>Formula:C20H20D4N2O3SColor and Shape:NeatMolecular weight:376.51rac Dropropizine
CAS:Controlled Product<p>Applications Dropropizine is a cough suppressant and central sedative therapeutic agent.<br>References Bakken, G., et al.: J. Med. Chem., 43, 4534 (2000), Salunkhe, M., et al.: Enz. Microb. Technol., 28, 333 (2001), Atul, B., et al.: J. Pharm. Sci., 91, 2067 (2002),<br></p>Formula:C13H20N2O2Color and Shape:WhiteMolecular weight:236.313-Hydroxy Anagrelide-13C3 (~80%)
CAS:Controlled Product<p>Applications 3-Hydroxy Anagrelide-13C3 is a major labelled metabolite of Anagrelide, an antithrombotic.<br>References Fleming, J., et al.: Thromb. Res., 15, 373 (1979), Gillespie, E., et al.: Biochem. Pharmacol., 37, 2866 (1988), Mazur, E., et al.: Blood, 79, 1931 (1992), Wang, G., et al.: Br. J. Pharmacol., 146, 324 (2005), Wagstaff, A., et al.: Drugs, 66, 111 (2006),<br></p>Formula:C713C3H7Cl2N3O2Purity:~80%Color and Shape:NeatMolecular weight:275.07Anastrozole Diacid
CAS:Controlled Product<p>Impurity Anastrozole Diacid Impurity<br>Applications Anastroloze Diacid is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic. Anastrozole Diacid Imp<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Formula:C17H21N3O4Color and Shape:WhiteMolecular weight:331.37N-Nitro-1,2,3,4-tetradehydro Argatroban
CAS:Controlled Product<p>Applications N-Nitro-1,2,3,4-tetradehydro Argatroban is an intermediate in the preparation of Argatroban (A769000).<br></p>Formula:C23H31N7O7SColor and Shape:White To Off-WhiteMolecular weight:549.60(S)-N-[2-[2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide
CAS:Controlled Product<p>Applications Intermediate in the production of Ramelteon.<br>References Uchikawa, O., et al.: J. Med. Chem., 45, 4222 (2002),<br></p>Formula:C16H23NO3Color and Shape:NeatMolecular weight:277.36Nintedanib 4-Nitrophenyl 2-(4-Nitroso)
Controlled ProductFormula:C13H17N5O4Color and Shape:NeatMolecular weight:307.305DL-threo-Droxidopa-d3 Hydrochloride Salt Hydrate
CAS:Controlled Product<p>Applications DL-threo-Droxidopa-d3 Hydrochloride Salt Hydrate is an isotope labeled compound of DL-threo-Droxidopa (D689950), a synthetic amino acid precursor of Norepinephrine. An Antiparkinson.<br>References Bartholini, J., et al.: J. Pharmacol. Exp. Ther ., 193, 523 (1975), Kato, T., et al.: Biochem. Pharmacol., 36, 3051 (1987), Kawabata, A., et al.: Br J. Pharmacol., 111, 503 (1994)<br></p>Formula:C9H8D3NO5•HCl•x(H2O)Color and Shape:NeatMolecular weight:216.21364618021,4,8,11-Tetraazacyclotetradecane
CAS:Controlled Product<p>Applications 1,4,8,11-Tetraazacyclotetradecane is macrocyclic ligand that is used as an antioxidant in rubber and has been shown to suppress oxidation catalyzed by some metal ions.<br>References Goh, S.H.: Poly, Degrad, Stab., 8, 123 (1984);<br></p>Formula:C10H24N4Color and Shape:NeatMolecular weight:200.322-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine[Aprepitant-M2]
CAS:Controlled Product<p>Applications A metabolite of Aprepitant.<br>References Ballard, T., et al.: Eur. J. Pharmacol., 412, 255 (2001), Campos, D., et al.: J. Clin. Oncol., 19, 1759 (2001), Severini, C., et al.: Pharmacol. Rev., 54, 285 (2002),<br></p>Formula:C20H18F7NO2Color and Shape:NeatMolecular weight:437.353-(Dibenzo[b,e]oxepin-11(6H)yl)-N,N-dimethylpropan-1-amine Hydrochloride
CAS:Controlled Product<p>Applications 3-(Dibenzo[b,e]oxepin-11(6H)yl)-N,N-dimethylpropan-1-amine Hydrochloride is an impurity of Doxepin (D550000), which is used clinically to treat anxiety and depression and is classified as an antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ribbentrop, A., et al.: Arzneim.-Forsch., 15, 863 (1965); Hobbs, D.C., et al.: Biochem. Pharmacol., 18, 1941 (1969); Pinder, R.M., et al.: Drugs, 13, 161 (1977); Shrivastava, R.K., et al.: Clin. Ther., 7, 181 (1985)<br></p>Formula:C19H23NO•(HCl)Color and Shape:NeatMolecular weight:281.393646N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide
CAS:Controlled Product<p>Applications N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide was used in the study to discover a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth. N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide is an impurity of Intedanib (I666650), which is an antitumor agent.<br>References Edupuganti, R., et al.: Bioorg. Med. Chem., 25, 2609 (2017); Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Formula:C29H31N5O2Color and Shape:NeatMolecular weight:481.59(±)-2-Phenylpropanoic Acid
CAS:<p>Applications Used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.<br>References Leeman, M. et al.: Angew. Chem. Int. Ed., 47, 1287 (2008); Eur. J. Med. Chem., 45, 3564 (2010);<br></p>Formula:C9H10O2Color and Shape:Light Yellow LiquidMolecular weight:150.174-Desisopropyl-4-ethyl Nateglinide
CAS:Controlled Product<p>Applications D-phenylanaline derivative and an analog Nateglinide (N379375) with similar hypoglycemic activity.<br>References Shinkai, H. et al.: J. Med. Chem., 32, 1436 (1989);<br></p>Formula:C18H25NO3Color and Shape:NeatMolecular weight:303.402-Acetylbutyrolactone
CAS:Controlled Product<p>Applications An intermediate in the synthesis of 2,4-disubstituted pyridines. A fluorogenic reagent for the spectrofluorimetric determination of primary amines.<br>References Toche, R.B. et al.: H. Heterocyclic Chem., 45, 1711 (2008); Sabry, S.M., J. Pharm. Biomed. Anal., 40, 1057 (2006);<br></p>Formula:C6H8O3Color and Shape:NeatMolecular weight:128.13Nitroso Norquetiapine-d8
Controlled ProductFormula:C17D8H8N4OSColor and Shape:NeatMolecular weight:348.4494-Desfluoro-2-Fluoro Droperidol
CAS:<p>Applications 4-Desfluoro-2-Fluoro Droperidol is an impurity of Droperidol (D679500), a D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic.<br>References Yelnosky, J., et al.: Toxicol. Appl. Pharmacol., 6, 37 (1964), Janicki, C.A., et al.: Anal. Profiles Drug Subs., 7, 171 (1978), Hamik, et al.: Cancer Chemother. Pharmacol., 24, 307 (1989), Heyer, E.J., et al.: Brain Res., 863, 20 (2000),<br></p>Formula:C22H22FN3O2Color and Shape:NeatMolecular weight:379.4274N-Methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide
CAS:Controlled Product<p>Applications N-Methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.<br>References Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003); Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004); Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004); Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)<br></p>Formula:C21H17F3N4O3Color and Shape:Off White To Light BrownMolecular weight:430.386a-Naloxol
CAS:Controlled Product<p>Applications 6α-Naloxol is a metabolite of Naloxone (N285000), a specific opioid antagonist. Narcotic antagonist.<br>References Chatterjie, N., et al.: J. Med. Chem., 18, 490 (1975); Bilsky, E., et al.: J. Pharmacol. Exp. Ther., 277, 484 (1996); Blokhina, E., et al.: Eur. J, Pharmacol., 406, 227 (2000); Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967); McNicholas, L.F., et al.: Drugs, 27, 81 (1984); Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985); Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)<br></p>Formula:C19H23NO4Color and Shape:NeatMolecular weight:329.39Tadalafil-13C2,d3
CAS:Controlled Product<p>Applications Tadalafil-13C2,d3 is labelled Tadalafil (T004500) which is used for the treatment of erectile dysfunction. It is a phosphodiesterase 5 inhibitor.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005)<br></p>Formula:C2013C2H16D3N3O4Color and Shape:White PowderMolecular weight:394.413-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane Bromide
CAS:Controlled Product<p>Applications 3-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane is an impurity in the synthesis of Clidinium Bromide (C576250), an anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Formula:C8H16BrNOColor and Shape:NeatMolecular weight:222.122-[[(3aR,4S,6R,6aS)-6-[[5-Amino-6-chloro-2-(propylthio)-4-pyrimidinyl]amino]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol
CAS:Controlled Product<p>Applications 2-[[(3aR,4S,6R,6aS)-6-[[5-Amino-6-chloro-2-(propylthio)-4-pyrimidinyl]amino]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol is used as a reagent in the synthesis of Ticagrelor (T437700) derivatives as antiplatelet agents.<br>References Zhang, H., et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012)<br></p>Formula:C17H27ClN4O4SColor and Shape:NeatMolecular weight:418.944’-Bromomethylbiphenyl-2-carboxylic Acid, Methyl Ester
CAS:Controlled ProductFormula:C15H13BrO2Color and Shape:NeatMolecular weight:305.17Methyl 3-chlorosulfonylthiophene-2-carboxylate
CAS:Controlled Product<p>Applications Methyl 3-chlorosulfonylthiophene-2-carboxylate<br></p>Formula:C6H5ClO4S2Color and Shape:NeatMolecular weight:240.68(E/Z)-Chlorprothixene-d6 Hydrochloride(Mixture)
CAS:Controlled Product<p>Applications Labelled cis/trans-Chlorprothixene (C424850). Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 63 (1973), Bagli, M., et al.: Arzneim.-Forsch., 46, 247 (1996),<br></p>Formula:C18H13D6Cl2NSColor and Shape:NeatMolecular weight:358.36N-Desethyl N-Methyl rac-Rivastigmine
CAS:<p>Impurity Rivastigmin USP Related Compound B<br>Applications N-Desethyl N-Methyl rac-Rivastigmine (Rivastigmin USP Related Compound B) is an impurity in the synthesis of Rivastigmine (R541000) a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C13H20N2O2Color and Shape:Clear ColourlessMolecular weight:236.31Ticagrelor Sulfone
CAS:Controlled Product<p>Applications Ticagrelor Sulfone is an impurity of ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Formula:C23H28F2N6O6SColor and Shape:NeatMolecular weight:554.57Risperidone 9-Ethylidenecarboxylate Hydrochloride
Controlled Product<p>Applications Risperidone 9-Ethylidenecarboxylate Hydrochloride, is the derivative of Risperidone (R525000), which is combined serotonin (5-HT2) and dopamine (D2) receptor antagonist, used for the treatment of schizophrenia, bipolar disorder and behavior problems in people with autism.<br>References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),<br></p>Formula:C25H27FN4O4Color and Shape:NeatMolecular weight:466.5036461-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid Sodium Salt
CAS:<p>Applications 1-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid is an impurity of Rabeprazole. It is also a degradation product formed in stressed tablets of Rabeprazole sodium.<br>References Kommanaboyina, B., et al.: Drug Dev. Ind. Pharm., 25, 857 (1999); Carswel, C., et al.: Drugs, 61, 2327 (2001); Garcia, C., et al.: J. Pharm. Biomed. Anal., 46, 88 (2008)<br></p>Formula:C14H10N3NaO3Color and Shape:NeatMolecular weight:291.244'-Desmethoxy Omeprazole
CAS:Controlled Product<p>Applications 4'-Desmethoxy Omeprazole is one of two impurities in the synthesis of Esomeprazole, an anti-ulcerative drug for treatment of acid-related diseases.<br>References Liu, X., et al.: Lat. Am. J. Pharm., 34, 1265-1268 (2015);<br></p>Formula:C16H17N3O2SColor and Shape:NeatMolecular weight:315.395-(Ethoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic Acid
CAS:Controlled ProductFormula:C17H18N2O6Color and Shape:NeatMolecular weight:346.33Nicoboxil
CAS:Controlled Product<p>Applications Nicoboxil is a medication used in the treatment of acute non-specific low back pains.<br>References Gaubitz, M., et al.: Eur. J. Pain , 20, 263 (2016),<br></p>Formula:C12H17NO3Color and Shape:ColourlessMolecular weight:223.27Lumateperone-d4
CAS:Controlled ProductFormula:C24D4H24FN3OColor and Shape:NeatMolecular weight:397.522Tipiracil Hydrochloride
CAS:Controlled Product<p>Applications Tipiracil Hydrochloride serves as a treatment for metastatic colorectal cancer (mCRC). A thymidine phosphorylase inhibitor.<br>References Sugita, K., et al.: Oncol., 91, 224-230 (2016); van der Velden, D. L., et al.: Clin. Cancer Res., 22, 2835-2839 (2016)<br></p>Formula:C9H11ClN4O2·(HCl)Color and Shape:White To Off-WhiteMolecular weight:242.66 + (36.46)5-(4'-Methyl-2-biphenyl)tetrazole-d4
CAS:Controlled Product<p>Applications Labelled Valsartan (V095750) impurity.<br>References Thai, H., et al.: J. Cardiovasc. Pharmacol., 50, 703 (2007), Lukas, J., et al.: Science, 313, 662 (2006),<br></p>Formula:C14H8D4N4Color and Shape:Off-WhiteMolecular weight:240.301Pazufloxacin Mesylate
CAS:Controlled Product<p>Applications A fluorinated quinolone antibiotic. Antibacterial.<br>References Fukuoka,Y., et al.: Antimicrob. Ag. Chemother., 37, 384 (1993), Todo, Y., et al.: Chem. Pharm. Bull., 42, 2569 (1994)<br></p>Formula:C16H15FN2O4·CH4O3SColor and Shape:NeatMolecular weight:414.41Brivaracetam-d7 (Mixture of Diastereomers)
Controlled Product<p>Applications Brivaracetam-d7 (Mixture of Diastereomers), is a mixture of 2 diastereomers of Brivaracetam-d7 (B677647), and a labeled analogue of Brivaracetam (B677645), 4-n-propyl analog of levetiracetam (L331500), and a racetam derivative with anticonvulsant properties.<br>References Rosenstiel, P., et al.:Neurotherapeutics, 4 (1), 84 (2007); Malawska, B., et al.:, Curr. Opin. Investig. Drugs, 6(7), 740 (2005);<br></p>Formula:C11H13D7N2O2Color and Shape:NeatMolecular weight:219.33Ticagrelor TCG Sulfonate
<p>Applications Ticagrelor TCG Sulfonate is an impurity of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Formula:C23H28F2N6O7S2Color and Shape:NeatMolecular weight:602.63Granisetron
CAS:Controlled Product<p>Applications Granisetron is a selective 5HT-3 antagonist.<br></p>Formula:C18H24N4OColor and Shape:NeatMolecular weight:312.41MRX-2843
CAS:Controlled Product<p>Applications MRX-2843, is an orally available small-molecule inhibitor of both MERTK and FLT3.<br>References Minson, K. A. et al.: JCI Insight. 2016 Mar;1(3):e85630.;<br></p>Formula:C29H40N6OColor and Shape:NeatMolecular weight:488.67Isoproturon-d3
CAS:Controlled Product<p>Applications Labelled Isoproturon. Pre-and post-emergence herbicide for control of annual grasses and broad-leaved weeds. Herbicide.<br>References Fournier, J.-C., et al.: Chemosphere, 4, 207 (1975), Gonzales, P., et al.: Weed Res., 23, 39 (1983),<br></p>Formula:C122H3H15N2OColor and Shape:White To Off-WhiteMolecular weight:209.30N-Nitroso-desethyl-Hydroxychloroquine
Controlled ProductFormula:C16H21ClN4O3Color and Shape:NeatMolecular weight:336.8172-Fluoro-4-desfluoro Bicalutamide
CAS:Controlled Product<p>Impurity Bicalutamide EP Impurity B<br>Applications Bicalutamide impurity. Bicalutamide derivative.<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988),<br></p>Formula:C18H14F4N2O4SColor and Shape:NeatMolecular weight:430.37343,4-Dihydro-1-phenylisoquinoline Hydrochloride
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications 3,4-Dihydro-1-phenylisoquinoline has been shown to have anesthetic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moore, M.B., et. al.: J. Am. Chem. Soc., 76, 3656 (1954)<br></p>Formula:C15H13N·ClHColor and Shape:NeatMolecular weight:243.73Irbesartan N-β-D-Glucuronide
CAS:<p>Applications A metabolite of Irbesartan (M8).<br>References Cazaubon, C., et al.: J. Pharmacol. Exp. Ther., 265, 826 (1993), Eberhardt, R., et al.: J. Clin. Pharmacol., 33, 1023 (1993), Huskey, S., et al.: Drug Metab. Dispos., 21, 792 (1993), van Den Meiracker, A., et al.: Hypertension, 25, 22 (1995),<br></p>Formula:C31H36N6O7Color and Shape:NeatMolecular weight:604.65Paliperidone N-Oxide
CAS:Controlled Product<p>Impurity Paliperidone USP Related Compound D<br>Applications One of the major degradation product of Risperidone in bulk drug and pharmaceutical dosage forms. Paliperidone USP Related Compound D.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leysen, J., et al.: J. Pharmacol. Exp. Ther., 247, 661 (1988), Huang, M., et al.: Pharm. Drug Dispos., 54, 257 (1993), Smyth, W., et al.: Anal. Bioanal. Chem., 378, 1305 (2004),<br></p>Formula:C23H27FN4O4Color and Shape:NeatMolecular weight:442.48Desmethyl-N-propyl Imiquimod
CAS:Controlled Product<p>Applications Desmethyl-N-propyl Imiquimod is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998); Gerster, J. et al.: J. Med. Chem., 48, 3481 (2005);<br></p>Formula:C13H14N4Color and Shape:NeatMolecular weight:226.285-(Chloromethyl)-α1,α1,α3,α3-tetramethyl-1,3-benzenediacetonitrile
CAS:Controlled ProductFormula:C15H17ClN2Color and Shape:NeatMolecular weight:260.76N-Desethyl N-Methyl Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity B<br>Applications N-Desethyl N-Methyl Rivastigmine (Rivastigmine EP Impurity B) is an impurity of Rivastigmine (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C13H20N2O2Color and Shape:NeatMolecular weight:236.324-Amino-2-fluoro-N-methylbenzamide
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications 4-Amino-2-fluoro-N-methylbenzamide acts as a reagent in the design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists. Also, in the preparation and structure-activity relationship of chiral benzyloxypyridinone derivatives as c-Met kinase inhibitors<br>References Ivachtchenko, A. V., et al.: Eur. J. Med. Chem., 99, 51 (2015); Zhang, D., et al.: Bioorg. Med. Chem. Lett., 23, 2408 (2013)<br></p>Formula:C8H9FN2OColor and Shape:NeatMolecular weight:168.17Rotigotine Hydrochloride
CAS:<p>Applications It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.<br>References Loschmann, P., et al.: Eur. J. Pharmacol., 166, 373 (1989), Edgar, D., et al.: J. Pharmacol. Exp. Ther., 283, 757 (1997), Ferreira, J., et al.: Lancet, 355, 1333 (2000), Arnulf, I., et al.: Neurology, 58, 1019 (2002), Wisor, J., et al.: Neuroscience, 132, 1027 (2005),<br></p>Formula:C19H25NOS·ClHColor and Shape:White To Off-WhiteMolecular weight:351.932-Amino-3-benzyloxypyridine
CAS:Controlled Product<p>Applications 2-Amino-3-benzyloxypyridine is used in preparation of pyridinyl/pyridazinyloxymethyl substituted Raf kinase inhibitors.<br>References Jen, T., et al.: J. Med. Chem., 20, 1258 (1977), Chung, D., et al.: Antican. Res., 11, 1373 (1991),<br></p>Formula:C12H12N2OColor and Shape:NeatMolecular weight:200.244-Chloro Perphenazine
CAS:Controlled Product<p>Applications 4-Chloro Perphenazine is an impurity of Perphenazine (P291100), an D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic.<br>References Briggs, K., et al.: Toxicology, 231, 113 (2007), Toga, T., et al.: J. Pharmacol. Sci., 105, 207 (2007),<br></p>Formula:C21H26ClN3OSColor and Shape:NeatMolecular weight:403.97Tadalafil Hydroxypiperidone
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Tadalafil Hydroxypiperidone, is an impurity of Tadalafil (T004500), a phosphodiesterase 5-inhibitor used for the treatment of erectile dysfunction.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005),<br></p>Formula:C22H19N3O6Color and Shape:NeatMolecular weight:421.4Dehydro Silodosin
CAS:Controlled Product<p>Applications Dehydro Silodosin is an impurity of Silodosin (S465000).<br>References Moriyama., et al.: Eur. J. Pharmacol., 331, 39 (1997), Zhu, J., et al.: Br. J. Pharmacol., 131, 546 (2000),<br></p>Formula:C25H30F3N3O4Color and Shape:NeatMolecular weight:493.52rac Toltrazuril Sulfoxide
CAS:<p>Applications Toltrazuril metabolite.<br>References Benoit, E., et al.: Biochem. Pharmacol., 46, 2337 (1993), Martinez-Villalba, A., et al.: Anal. Bioanal. Chem., 397, 2893 (2010),<br></p>Formula:C18H14F3N3O5SColor and Shape:Off-WhiteMolecular weight:441.383-[2-[4-(6-Fluoro-2-benzoxazolyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone Impurity)
CAS:Controlled ProductFormula:C23H27FN4O2Color and Shape:NeatMolecular weight:410.48N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS:Controlled Product<p>Applications Intermediate in the preparation of Imatinib impurities. It is a COVID19-related research product.<br></p>Formula:C16H15N5Color and Shape:NeatMolecular weight:277.325-Amino-4-(4-nitro-1-oxoisoindolin-2-yl)-5-oxopentanoic Acid
CAS:Controlled ProductFormula:C13H13N3O6Color and Shape:Off-WhiteMolecular weight:307.2592,2’-Methylene Bis[Ranitidine]
CAS:Controlled Product<p>Impurity Ranitidine EP Impurity I<br>Stability Light Sensitive, Temperature Sensitive<br>Applications 2,2’-Methylene Bis[Ranitidine] (Ranitidine EP Impurity I) is an impurity of histamine H2-receptor antagonist Ranitidine (R120000).<br>References Jones, M.D. et al.: J. Sep. Sci., 29, 2409 (2006); Kelly, M.A. et al.: J. Chrom. A, 798, 297 (1998);<br></p>Formula:C27H44N8O6S2Color and Shape:NeatMolecular weight:640.82Cinitapride
CAS:<p>Applications A novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors (1,2,3).<br>References (1) Alarcon de la Lastra, C. et al.: Pharmacol, 54, 193 (1997)(2) Robert, M. et al.: Drug Metab. Disp., 35, 1149 (2007)(3) Alarcon de la Lastra, C. et al.: Inflam. Res., 47, 131 (1998)<br></p>Formula:C21H30N4O4Color and Shape:NeatMolecular weight:402.492-Methylthieno[2,3-d]isothiazol-3(2H)-one 1,1-Dioxide
CAS:Controlled ProductFormula:C6H5NO3S2Color and Shape:NeatMolecular weight:203.242-Nitroso Riluzole
Controlled Product<p>Applications 2-Nitroso Riluzole is an impurity of Riluzole (R510000); is a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. Neuroprotective agent.<br>References Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Formula:C8H3F3N2O2SColor and Shape:Dark GreenMolecular weight:248.182S-(+)-Arundic Acid
CAS:Controlled Product<p>Applications The S-enantiomer of Arundic Acid. An astrocyte modulating agent, in acute ischemic stroke. A therapeutic agent for the treatment of neurodegenerative diseases including Alzheimer's disease and Parkinson’s disease.<br>References Uchida, Y., et al.: Brain Res., 481, 190 (1989), Tokunaga, M., et al.: Science, 277, 936 (1997), Sorbera, L., et al.: Drugs Future, 29, 441 (2004),<br></p>Formula:C11H22O2Color and Shape:NeatMolecular weight:186.29Everolimus Isomer C (>60%, contains everolimus)
CAS:Controlled Product<p>Stability Unstable in solution, revert back to Everolimus<br>Applications Everolimus Isomer C is an isomer of Everolimus (E945400), a derivative of Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)<br></p>Formula:C53H83NO14Color and Shape:NeatMolecular weight:958.22Anagrelide-13C3
CAS:Controlled ProductFormula:C713C3H7Cl2N3OColor and Shape:NeatMolecular weight:259.071-(2,4-Bis(benzyloxy)phenyl)ethanone
CAS:Controlled Product<p>Applications 1-(2,4-Bis(benzyloxy)phenyl)ethanone is a useful research chemical for organic synthesis and other chemical processes.<br>References Chen, D., et al.: Eur. J. Med. Chem., 87, 765 (2014); Malik, N., et al.: Tetrahedron Lett., 54, 4121 (2013)<br></p>Formula:C22H20O3Color and Shape:NeatMolecular weight:332.39Leflunomide EP Impurity G
CAS:Controlled ProductFormula:C12H12N2O2Color and Shape:NeatMolecular weight:216.24Dacomitinib
CAS:Controlled Product<p>Applications Dacomitinib is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.<br>References Williams, J. et al.: PLoS., 9, e98557 (2014); Peters, S. et al.: Canc. Treatment Rev., 40, 917 (2014);<br></p>Formula:C24H25ClFN5O2Color and Shape:NeatMolecular weight:469.941-Phenyl-2-propen-1-one (Contains ~1% BHT as stabilizer)
CAS:<p>Stability Light and Temperature Sensitive<br>Applications 1-Phenyl-2-propen-1-one is a chemical reagent used in the synthesis of pharmaceutical agents. Used in the preparation of functionalized aminoindolizines as well as pyrano[3,2-x]coumarins.<br>References Wang, D. et al.: Asian J. Org. Chem., 2, 480 (2013); Gohain, M. et al.: Tetrahedron Lett., 54, 3773 (2013);<br></p>Formula:C9H8OColor and Shape:NeatMolecular weight:132.159Ivabradine-d3 Hydrochloride
CAS:Controlled Product<p>Stability very hygroscopic<br>Applications Labelled Ivabradine (I940500). Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994), Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998), Borer, J.S., et al.: Circulation, 107, 817 (2003), DiFrancesco, D., et al.: Drugs, 64, 1757 (2004),<br></p>Formula:C272H3H33N2O5·ClHColor and Shape:NeatMolecular weight:508.06(3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester
CAS:Controlled ProductFormula:C24H21N3O3Color and Shape:NeatMolecular weight:399.442-Acetylbenzothiophene
CAS:Controlled Product<p>Applications A novel anti-osteoporosis agent, by enhansing expression of the BMP-2 gene.<br>References Horiguchi, Y., et al.: Chem. Pharm. Bull., 52, 214 (2004), Joshi, E., et al.: Chem. Res. Toxicol., 17, 137 (2004), Liu, Z., et al.: Bioorg. Med. Chem. Lett., 19, 4167 (2009),<br></p>Formula:C10H8OSColor and Shape:NeatMolecular weight:176.23Quetiapine Dimer Impurity-d8
CAS:Controlled Product<p>Applications An impurity of labelled Quetiapine.<br>References Xu, H., et al.: J. Pharm. Biomed. Anal., 47, 658 (2008), Stolarczyk, E., et al.: Pharm. Develop. Technol., 14, 27 (2009),<br></p>Formula:C30H16D8N4S2Color and Shape:NeatMolecular weight:512.72α-Phenyl-2-pyridineacetamide
CAS:Controlled Product<p>Applications α-Phenyl-2-pyridineacetamide (cas# 7251-52-7) is a compound useful in organic synthesis.<br></p>Formula:C13H12N2OColor and Shape:NeatMolecular weight:212.25Loxapine, Succinate
CAS:Controlled Product<p>Applications A D2/D4-Dopamine receptor antagonist. A serotonergic receptor antagonist. A dibenzoxazepine antipsychotic agent.<br>References Shen, Y., et al.: J. Biol. Chem., 268, 18200 (1993), Fiorella, D., et al.: Psychopharmacology, 121, 347 (1995), Glusa, E., et al.: Br. J. Pharmacol., 130, 692 (2000)<br></p>Formula:C18H18ClN3O·C4H6O4Color and Shape:WhiteMolecular weight:445.902-(2,4-Difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)-1,2-propanediol
CAS:Controlled Product<p>Impurity Fluconazole EP Impurity F<br>Stability Hygroscopic<br>Applications 2-(2,4-Difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)-1,2-propanediol (Fluconazole EP Impurity F) is a diol impurity of the antifungal agent Fluconazole (F421000).<br>References Dongre, V.G. et al.: J. Pharmac. Biomed. Anal., 42, 334 (2006):<br></p>Formula:C11H11F2N3O2Color and Shape:Light YellowMolecular weight:255.22(S)-Hydroxy Timolol
CAS:Controlled Product<p>Applications (S)-(-)-Hydroxy Timolol is a metabolite of the non-selective beta-adrenergic receptor blocker, Timolol (T443710).<br>References Volotinen, M. et al.: Basic Clin. Pharmacol. Toxicol., 106, 302 (2010);<br></p>Formula:C13H24N4O4SColor and Shape:NeatMolecular weight:332.424-[[3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl]carbonyl]-1-piperidinecarboxylic AcidEthyl Ester
CAS:Controlled Product<p>Applications Loratadine intermediate, as antiallergic agent.<br></p>Formula:C22H25ClN2O3Color and Shape:NeatMolecular weight:400.90Hydroxy Atrazine-d5
CAS:Controlled Product<p>Applications Labelled Hydroxy Atrazine (H828600). Hydroxy Atrazine is a major metabolite of Atrazine (A794600).<br>References Thurman, E., et al.: Environ. Sci. Technol., 26, 2440 (1992), Evgenidou, E., et al.: J. Agric. Food Chem., 50, 6423 (2002), Namiesnik, J., et al.: Anal. Bioanal. Chem., 381, 279 (2005), Hultgren, S., et al.: Anal. Bioanal. Chem., 393, 929 (2009),<br></p>Formula:C82H5H10N5OColor and Shape:NeatMolecular weight:202.275'-Hydroxyphenyl Carvedilol-d5
CAS:Controlled Product<p>Applications A Labelled metabolite of Carvedilol which is a multiple-action, neurohormonal antagonist that is used in the treatment of hypertension.<br>References Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 958 (1998).<br></p>Formula:C24H21D5N2O5Color and Shape:NeatMolecular weight:427.52’-Des(1-hydroxy-1-methylethyl)-2’-methycarboxy Montelukast Hydrochloride
CAS:Controlled Product<p>Applications 2’-Des(1-hydroxy-1-methylethyl)-2’-methycarboxy Montelukast Hydrochloride is an impurity of Montelukast (M568000), a selective leukotriene D4-receptor antagonist.<br>References Kumar, I.V. et al.: Asian J. Chem., 23, 4536 (2011)<br></p>Formula:C34H33Cl2NO4SColor and Shape:NeatMolecular weight:622.6Benzil
CAS:<p>Applications Benzil is used in organic synthesis as a building block and in polymer chemistry as a photoinitiator. It has also been found to be an inhibitor of mammalian carboxylesterases.<br>References Encinas, M., et al.: J. Polym. Sci. A1., 22, 2469 (1984); Wadkins, R., et al.: J. Med. Chem., 48, 2906 (2005); Hicks, L., et al.: Bioorgan. Med. Chem., 15, 3801 (2007);<br></p>Formula:C14H10O2Color and Shape:NeatMolecular weight:210.231-(3,4-Dimethylphenyl)ethanol
CAS:Controlled Product<p>Applications 1-(3,4-Dimethylphenyl)ethanol is an intermediate in the production of Medetomidine (M203250), α2-Adrenergic agonist. Sedative; analgesic.<br>References Kagechika, H., et al.: J. Med. Chem., 32, 1098 (1989), ; Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987),<br></p>Formula:C10H14OColor and Shape:NeatMolecular weight:150.22(2R,6S)-rel-2,6-Dimethyl-4-(2-methyl-3-phenylpropyl)morpholine Hydrochloride
CAS:<p>Impurity Amorolfine EP Impurity C<br>Stability Hygroscopic<br>Applications (2R,6S)-rel-2,6-Dimethyl-4-(2-methyl-3-phenylpropyl)morpholine Hydrochloride (1:1), is used in the preparation of Amorolfine (A634170), a morpholine antifungal drug.<br>References Rotta, I., et al.: JAMA Dermatol., 149, 341 (2013); Espinel-Ingroff, A., et al.: Antimicrob. Agents Ch., 26, 5 (1984)<br></p>Formula:C16H26ClNOColor and Shape:NeatMolecular weight:283.84Tofogliflozin
CAS:Controlled Product<p>Applications A novel, potent, and highly selective SGLT2 inhibitor that has been shown to improve glycemic control in diabetic mice and rats.<br></p>Formula:C22H26O6Color and Shape:NeatMolecular weight:386.44(R)-1-Methyl-3-pyrrolidinol
CAS:Controlled Product<p>Applications (R)-1-Methyl-3-pyrrolidinol is a useful synthetic intermediate. It is used for asymmetric synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.<br>References Isakovic, L., et al.: Bioorg. Med. Chem. Lett., 19, 2742 (2009); Gobbini, M., et al.:J. Med. Chem., 51, 4601 (2008)<br></p>Formula:C5H11NOColor and Shape:NeatMolecular weight:101.15N-[(2,4-Difluorophenyl)methyl]-1,8-dihydro-9-hydroxy-2-[(1R)-3-hydroxy-1-methylpropyl]-1,8-dioxo-2H-pyrido[1,2-a]pyrazine-7-carboxamide
CAS:Controlled ProductFormula:C20H19F2N3O5Color and Shape:YellowMolecular weight:419.384-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone
CAS:Controlled ProductFormula:C21H21N3O5Color and Shape:NeatMolecular weight:395.41Resiquimod
CAS:<p>Applications Resiquimod is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.<br>References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);<br></p>Formula:C17H22N4O2Color and Shape:White SolidMolecular weight:314.383’-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]propyl Domperidine (Domperidine Impurity F)
CAS:Controlled Product<p>Impurity Domperidone EP Impurity F<br>Applications An impurity of the gastrokinetic and antinauseant drug Domperidone (D531100(P)), which is a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent.<br>References Baudry, M., et al.: Arch. Pharmacol., 308, 231 (1979), Ennis, C., et al.: J. Pharm. Pharmacol., 31, 14 (1979), Brogden, R.N., Drugs, 24, 360 (1982),<br></p>Formula:C37H42Cl2N8O3Color and Shape:NeatMolecular weight:717.69Pimavanserin N-Oxide
CAS:Controlled Product<p>Applications Pimavanserin N-Oxide is an impurity of Pimavanserin (P441800), a drug used in the treatment of Parkinson’s disease and psychosis.<br>References Snigdha, S., et al.: J. Pharmacol. Exper. Ther., 332, 622 (2010); Meltzer, H., et al.: Neuropsychopharmacol., 35, 881 (2010);<br></p>Formula:C25H34FN3O3Color and Shape:NeatMolecular weight:443.55Perampanel-d5
CAS:Controlled Product<p>Applications Perampanel-d5, is the labeled analogue of Perampanel (P285520), an antiepileptic drug.<br>References Shih, J., et al.: Therap. Clinical Risk Management, 9, 285 (2013); Rogawski, M. A., et al.: Epilepsy Curr., 11, 56 (2011);<br></p>Formula:C23D5H10N3OColor and Shape:Light Orange Colour SolidMolecular weight:354.422,3,3a,12b-Tetradehydro Asenapine
CAS:Controlled ProductFormula:C17H12ClNOColor and Shape:NeatMolecular weight:281.74(S)-α-Hydroxy-β-methoxy-β-phenyl-benzenepropanoic Acid Methyl Ester
CAS:Controlled Product<p>Impurity Ambrisentan Hydroxyester Impurity<br>Applications (S)-α-Hydroxy-β-methoxy-β-phenyl-benzenepropanoic Acid Methyl Ester is an impurity in the synthesis of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive. (Ambrisentan Hydroxyester Impurity)<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),<br></p>Formula:C17H18O4Color and Shape:NeatMolecular weight:286.32Dimethylamine (40% aq.)
CAS:Controlled Product<p>Applications Dimethylamine (40% aq.) is a compound often used in industry as a precursor to Nitrosodimethylamine (N525625), a potent carcinogen that is produced during disinfection of wastewater effluent, and is also present in trace amounts in food and polluted air. Dimethylamine is also present in human urine and can be indicative of certain disorders.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gereke, A. & Sedlak, D.: Env. Sci. Tech., 37, 1331 (2003); Mitch, W., et al.: Env. Eng. Sci., 20, 389 (2003); Tsikas, D., et al.: J. Chromatogr. B, 851, 229 (2007)<br></p>Formula:C2H7NColor and Shape:NeatMolecular weight:45.082-(2-Methoxyethyl)phenol
CAS:Controlled Product<p>Applications 2-(2-Methoxyethyl)phenol is used as a stabilizer in the preparation of polysiloxane based coating compounds with good stability.<br></p>Formula:C9H12O2Color and Shape:NeatMolecular weight:152.19Nintedanib Demethyl-O-glucuronic Acid
CAS:Formula:C36H39N5O10Color and Shape:NeatMolecular weight:701.726,8-Dioxo Apalutamide
CAS:Controlled Product<p>Applications 6,8-Dioxo Apalutamide is an impurity of Apalutamide (A726120). Apalutamide is a second-generation antiandrogen used in the treatment of prostate cancer.<br>References Li, Huifang, et al.: J. of Chem. Info. and Model., 53(1), 123-130 (2013);Joseph, James D., et al.: Cancer Disc., 3(9), 1020-1029 (2013)<br></p>Formula:C21H15F4N5O3Color and Shape:NeatMolecular weight:461.38Selexipag D-Mannitol Ester (>80%)
Controlled ProductFormula:C31H41N3O8Purity:>80%Color and Shape:NeatMolecular weight:583.68O-Desethyl Resiquimod-d6
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications O-Desethyl Resiquimod-d6 is the labelled analogue of O-Desethyl Resiquimod (D228575), which is derived from its parent compound Resiquimod (R144680), which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.<br>References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);<br></p>Formula:C15H12D6N4O2Color and Shape:NeatMolecular weight:292.37Omeprazole Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Omeprazole Sodium Salt is the salt analogue of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H18N3O3S·Na·H2OColor and Shape:Off-WhiteMolecular weight:385.412-Methylisoindole-1,3-dione
CAS:Controlled Product<p>Applications Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene h and the selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one have been studied.<br>References Mazzocchi, P., et al.: J. Am. Chem. Soc., 106, 7567 (1984); Villagran, C., et al.: Ultrasonics Sonochemistry, 12, 423 (2005)<br></p>Formula:C9H7NO2Color and Shape:NeatMolecular weight:161.162-(Bromomethyl)-3-nitrobenzoic Acid Methyl Ester
CAS:Controlled Product<p>Applications 2-(Bromomethyl)-3-nitrobenzoic Acid Methyl Ester (cas# 98475-07-1) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C9H8BrNO4Color and Shape:Off-White To Light YellowMolecular weight:274.07rac erythro-Dihydro Bupropion-d9
CAS:Controlled Product<p>Applications A labelled metabolite of the drug Bupropion (B689625).<br>References Hsyu, P-H., et al.: J. Clin. Pharmacol., 37, 737 (1997)<br></p>Formula:C13H11D9ClNOColor and Shape:NeatMolecular weight:250.81Loratadine-d5 (ethyl-d5)
CAS:Controlled Product<p>Applications Loratadine-d5 (ethyl-d5) (CAS# 1398065-63-8) is a useful isotopically labeled research compound.<br></p>Formula:C22D5H18ClN2O2Color and Shape:NeatMolecular weight:387.923-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione
CAS:<p>3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione is a research and development impurity standard. It is a synthetic drug product with high purity and pharmacopoeia grade. 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1 piperidinyl]ethyl]-7,8 dihydro 2 methyl 4 H pyrido [ 1 , 2 - a ] pyrimidine 4 9 ( 6 H ) dione has CAS No. 118951665 1 and is an analytical standard for HPLC analysis. 3-[2-[4-(6 Fluoro 1 , 2 benzisox</p>Formula:C23H25FN4O3Purity:Min. 95%Molecular weight:424.47 g/molRegorafenib metabolite M2 oxide
CAS:<p>Regorafenib metabolite M2 oxide (M2O) is a cancer drug that is an inhibitor of multikinase. It was developed as a prodrug for regorafenib, which is used to treat patients with metastatic colorectal cancer and has been shown to be effective against other cancers, such as lung and pancreatic cancer. M2O inhibits the efflux of drugs from cells by binding to the transporter protein P-glycoprotein. This prevents the accumulation of toxic concentrations of regorafenib in cells, which are responsible for its side effects, such as diarrhea and liver damage. The uptake of M2O by cells is also inhibited by light and acidic conditions. Oral administration of M2O leads to increased exposure to regorafenib in the body because it is not metabolized by CYP3A4 enzymes.</p>Formula:C21H15ClF4N4O4Purity:Min. 95%Molecular weight:498.81 g/mol2,12-Dihydro-1,3-dimethyl-8-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one
CAS:<p>2,12-Dihydro-1,3-dimethyl-8-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a metabolite of the drug 2-[2-(4,5,-dihydroimidazo[1,2a]imidazol -2(3H)-yl)ethoxy]-N-(methylsulfonyl)benzamide. It can be used as an impurity standard for the manufacture of drugs and as a research chemical.</p>Formula:C16H13N3O2SPurity:Min. 95%Molecular weight:311.36 g/molCinacalcet impurity B
CAS:<p>Cinacalcet impurity B is an amine that is a by-product of the manufacturing process for cinacalcet. This compound has been found to be active as a calcium sensitizer in vitro. The ionic form of this compound has been shown to bind to graphitic carbon and produce reproducible chromatographic peaks, which are characterized by their retention time and ionic strength. Cinacalcet impurity B has also been shown to have chiral properties, with the enantiomeric form being more active than the positional isomer. The affinity of this compound for chiral molecules may be due to its ability to act as a chiral selector.</p>Formula:C19H19NPurity:Min. 95%Molecular weight:261.36 g/mol2-[(4-Chloro-3-methyl-2-pyridinyl)methylthio]-1H-benzimidazole
CAS:<p>2-[(4-Chloro-3-methyl-2-pyridinyl)methylthio]-1H-benzimidazole is a drug product. It is an impurity standard for the analytical determination of 2-[(4-chloro-3-methylpyridin)-2yl]thiohydantoin in pharmaceuticals and other chemical products. This compound is also used as a research and development (R&D) metabolite and impurity standard for the synthesis of 4-(4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)pyridine. The CAS number for this compound is 103312-62-5./END></p>Formula:C14H12ClN3SPurity:Min. 95%Molecular weight:289.78 g/molRivaroxaban impurity 79
CAS:<p>Please enquire for more information about Rivaroxaban impurity 79 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C38H38N4O12Purity:Min. 95%Molecular weight:742.74 g/mol6-Des(1-methyl-2-benzimidazolyl)-6-carboxy telmisartan
CAS:<p>Telmisartan is a drug that belongs to the class of angiotensin II receptor antagonists and is used in the treatment of hypertension. Telmisartan can be quantitatively analyzed with high sensitivity by liquid chromatography. Impurities in telmisartan can be analyzed qualitatively and quantitatively by liquid chromatography, which requires a shorter time than GC analysis.</p>Formula:C26H24N2O4Purity:Min. 95%Molecular weight:428.48 g/molN2-Methyl alfuzosin-D7 hydrochloride
CAS:<p>N2-Methyl alfuzosin-D7 is a drug product that belongs to the group of alfuzosin, which is a selective inhibitor of the enzyme phosphodiesterase type 5 (PDE5) and is used for the treatment of benign prostatic hyperplasia. It has been designed to reduce the risk of adverse effects associated with other PDE5 inhibitors, such as erectile dysfunction and urinary retention. N2-Methyl alfuzosin-D7 has been shown to be effective in animal studies and in vitro experiments. However, its metabolism remains unknown.</p>Formula:C19H21D7ClN5O4Purity:Min. 95%Molecular weight:432.95 g/mol2-[(R)-[(1S)-2-Methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetic acid
CAS:<p>2-[(R)-[(1S)-2-Methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetic acid is a metabolite of the drug product, 2-[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinic acid. It is an impurity standard for the analytical determination of 2-[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinic acid in both drug products and in synthetic intermediates. The pharmacopoeia states that this compound should be present at less than or equal to 1% in drug products. This metabolite has been shown to have antiinflammatory activity.</p>Formula:C19H29O6PPurity:Min. 95%Molecular weight:384.4 g/molDi-destriazole anastrozole dimer impurity
CAS:<p>Di-destriazole anastrozole dimer impurity is a synthetic impurity that is created during the synthesis of anastrozole. It has been studied as a possible metabolite of the drug, but its role in metabolism is not well understood. Di-destriazole anastrozole dimer impurity is soluble in water and methanol and has a melting point of between 1°C to 2°C. The purity of this compound is typically at least 99% with a specific gravity of 1.043 g/mL.</p>Formula:C26H29N3Purity:Min. 95%Molecular weight:383.53 g/mol3-(Methylamino)-1-(2-thienyl)propan-1-ol
CAS:<p>3-(Methylamino)-1-(2-thienyl)propan-1-ol is a lipase inhibitor that belongs to the group of 1-fluoronaphthalene. It is an efficient method for the demethylation of 1-fluoronaphthalene, which is used in the synthesis of many pharmaceuticals. The synthesis of this compound was achieved through a kinetic study and confirmed by x-ray crystallography. This compound has been shown to be an analytical method for the determination of impurities in other drugs. 3-(Methylamino)-1-(2-thienyl)propan-1-ol can also be used as a drug substance for other pharmaceuticals and has been shown to inhibit the transfer of chiral centers mediated by enzymes and substrates.</p>Formula:C8H13NOSPurity:Min. 95%Molecular weight:171.26 g/mol1,1'-[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol
CAS:<p>1,1'-[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol] is a synthetic drug product that has been custom synthesized for testing purposes. It is one of the metabolites of the drug product 1,1'-[(1-Methylethyl)imino]bis[3-[4-(2-hydroxypropyl)phenoxy]-2-propanol]. The metabolite has not been found in nature and its structure is unknown. Metabolism studies have been performed on this metabolite to determine its metabolic pathway. This metabolite is an impurity standard for HPLC analysis.</p>Formula:C27H41NO6Purity:Min. 95%Molecular weight:475.62 g/mol3-[2-[4-(2,4-Difluorobenzoyl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>Roflumilast is a drug used to treat chronic obstructive pulmonary disease. It is also used to treat inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. Roflumilast inhibits the enzyme cytochrome P450 in the liver, which is responsible for metabolizing certain drugs and other substances. This inhibition reduces the metabolism of these substances, leading to increased levels of these substances in the body. This can lead to side effects such as nausea, vomiting, dizziness, headache, and itching. Roflumilast also has an anti-inflammatory effect on the intestines by regulating the production of inflammatory cytokines and inhibiting the activity of pro-inflammatory enzymes.</p>Formula:C23H27F2N3O2Purity:Min. 95%Molecular weight:415.48 g/molToremifene-N-oxide
CAS:<p>Toremifene-N-oxide is a drug that has been shown to have genotoxic effects in human liver cells in an incubated system. Toremifene-N-oxide is the active form of toremifene, which is a selective estrogen receptor modulator (SERM). Toremifene-N-oxide is metabolized by peroxidases and can react with reactive oxygen species (ROS) to produce DNA damage. It also binds to DNA at the site of supercoiled DNA, leading to changes in the molecule's structure. Toremifene-N-oxide has been shown to have an optimum pH of 7.4 and ionization mass of 367. This drug binds to lactoperoxidase found in human liver cells and produces reactive molecules that cause oxidative DNA damage.</p>Formula:C26H28ClNO2Purity:Min. 95%Molecular weight:421.96 g/mol5-O-Desethyl amlodipine
CAS:<p>5-O-Desethyl amlodipine is a metabolite of amlodipine. It has been used as an analytical reference standard for the determination of amlodipine and its metabolites in human plasma and urine. 5-O-Desethyl amlodipine has been reported to be excreted in human breast milk at a concentration that is about 20% of that found in maternal plasma. The drug product is manufactured by HPLC and is classified as a high purity pharmaceutical drug, which means it is free from extraneous substances such as other drugs, proteins, or bacteria.</p>Formula:C18H21ClN2O5Purity:Min. 95%Molecular weight:380.82 g/molDemethylpiperazinyl sildenafil sulfonic acid
CAS:<p>Demethylpiperazinyl Sildenafil Sulfonic Acid is a prodrug of sildenafil, which is an organic compound. It is used in the treatment of erectile dysfunction and pulmonary arterial hypertension. This drug is metabolized by hydrolysis to form sildenafil citrate, which then acts as an inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5). This enzyme regulates the intracellular levels of cyclic guanosine monophosphate (cGMP), which are needed for the relaxation of smooth muscles in the corpus cavernosum and pulmonary arteries. Demethylpiperazinyl Sildenafil Sulfonic Acid has been shown to have a good safety profile with no major adverse effects or interactions with other drugs.</p>Formula:C17H20N4O5SPurity:Min. 95%Color and Shape:PowderMolecular weight:392.43 g/mol(3S,4S,3’S)-Ezetimibe
CAS:<p>Please enquire for more information about (3S,4S,3’S)-Ezetimibe including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C24H21F2NO3Purity:Min. 95%Molecular weight:409.43 g/molAnastrozole dimer impurity
CAS:<p>Anastrozole is an aromatase inhibitor that has been used in the treatment of breast cancer. It binds competitively to the heme moiety of aromatase, blocking its access to substrate and thereby inhibiting estrogen production. Anastrozole dimer impurity is an analytical impurity found in drug products that is not a natural component of the API (active pharmaceutical ingredient). CAS No. 1216898-82-6 refers to this impurity standard as well as other synthetic analogues. This impurity is a custom synthesis with no pharmacopoeia standards for purity. The HPLC standard for this product is high purity (99%).</p>Formula:C30H31N9Purity:Min. 95%Molecular weight:517.63 g/mol(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
CAS:<p>Please enquire for more information about (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C16H12F6N4OPurity:Min. 95%Molecular weight:390.28 g/molChlorhexidine digluconate EP Impurity L
<p>Chlorhexidine digluconate EP Impurity L is a metabolite of chlorhexidine digluconate. It is an impurity found in the drug product, which is used for the treatment of skin and mucous membrane infections. The mechanism of action for chlorhexidine digluconate EP Impurity L is not known. However, it has been shown to be metabolized by CYP3A4 and CYP2C9 enzymes to form chlorhexidine acetate, a metabolite that inhibits bacterial growth, and hydrolyzed by esterases to form 2-hydroxychlorhexidine acetate. This metabolite has been found in the urine of rats following oral administration with chlorhexidine digluconate EP Impurity L.</p>Formula:C13H15ClN2O6Purity:Min. 95%Molecular weight:330.72 g/molSalbutamol Impurity D
CAS:<p>Salbutamol Impurity D is a chiral, metal chelator impurity of the drug substance Salbutamol. It is a prodrug that is hydrolyzed to its active form, salbutamol sulfate, in vivo. Salbutamol Impurity D binds to chloride ions and has been shown to be an interferent for many analytical methods. The reversed-phase chromatography retention time for Salbutamol Impurity D is about 10 minutes shorter than for Salbutamol sulfate.</p>Formula:C13H19NO3Purity:Min. 95%Molecular weight:237.29 g/molN-Methyl omeprazole (Mixture of isomers with the methylated nitrogens of imidazole)
<p>Please enquire for more information about N-Methyl omeprazole (Mixture of isomers with the methylated nitrogens of imidazole) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C18H21N3O3SPurity:Min. 95%Molecular weight:359.44 g/molAlfuzosin hydrochloride EP Impurity F hydrochloride
CAS:<p>Alfuzosin EP Impurity F hydrochloride is a drug product that is used as an analytical standard for Alfuzosin hydrochloride. It is a natural, synthetic, and impurity standard that exhibits similar chromatographic properties to the API. The CAS number of this impurity is 19216-68-3. This product has a niche market because it is used in metabolism studies. It also exhibits high purity and pharmacopoeia grade quality.</p>Formula:C12H16N4O2•HClPurity:Min. 95%Molecular weight:284.74 g/mol(3R)-Tetrahydrofuran-3-yl 4-Methylbenzenesulfonate
CAS:<p>Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is a synthetic compound that has been used as an impurity standard for the drug product and as a metabolite in pharmacopoeia. Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is also used in research and development, including drug metabolism studies. Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is a high purity and custom synthesis that is used as an analytical standard for HPLC.</p>Formula:C11H14O4SPurity:Min. 95%Molecular weight:242.29 g/molN2-Losartanyl-losartan
CAS:<p>N2-Losartanyl-losartan is a drug product that has a CAS number of 230971-72-9. This product is an analytical standard for the metabolites of losartan, which is a drug used to treat high blood pressure and heart failure. Metabolism studies have shown that losartan is metabolized by hydroxylation, glucuronidation, and oxidation by cytochrome P450 enzymes. Losartan has also been found to be converted into an active metabolite in the body, which is called N2-hydroxy-losartan. It has been shown to be more potent than losartan at blocking angiotensin II receptors.</p>Formula:C44H44Cl2N12OPurity:Min. 95%Molecular weight:827.81 g/molDeiodo amiodarone
CAS:<p>Deiodo amiodarone is a noncompetitive inhibitor that binds to the active site of the enzyme and blocks the binding of substrate, thereby inhibiting the synthesis of catecholamines. Deiodo amiodarone has been shown to inhibit the oxidation of benzofuran derivatives in rat liver microsomes, human liver tissue samples, and chromatographic conditions. The inhibition constant for deiodo amiodarone was determined by liquid chromatography with a homogenizing technique.</p>Formula:C25H30INO3Purity:Min. 95%Molecular weight:519.42 g/molMontelukast Bis-sulfide(mixture of diastereomers)
CAS:<p>Montelukast Bis-sulfide is a drug product that is custom synthesized with high purity. It has been studied for its metabolism, analytical properties, and natural sources. The metabolite of montelukast bis-sulfide has been extensively researched for pharmacopoeia as well as for drug development. Montelukast bis-sulfide is a synthetic compound that is not found in nature, but it has niche applications in research and development. CAS No.: 1242260-05-4</p>Formula:C41H46ClNO5S2Purity:Min. 95%Molecular weight:732.39 g/molRoflumilast Impurity E
CAS:<p>Roflumilast Impurity E is a reagent that is used to monitor the pharmacokinetic properties of roflumilast. Roflumilast Impurity E is an acidic component of roflumilast that may be synthesized from acetone and acid hydrolysis. It has been shown to be hepatotoxic, but it does not have any adverse effects on the liver when taken with other drugs such as erythromycin and phenytoin. This substance also has a spectrum of action that includes pulmonary disease, which makes it useful for treating bronchitis and asthma.</p>Formula:C13H8Cl2F2N2O3Purity:Min. 95%Molecular weight:349.12 g/mol4-Desmethyl-3-methyl celecoxib
CAS:<p>This compound is a drug product that is used as an analytical standard for the identification of impurities. This compound is also a Metabolism studies, Natural, API impurity, Custom synthesis, Impurity standard, Synthetic and Drug development research chemical. The CAS number for this compound is 170570-01-1 and it has HPLC standards with high purity. This compound is also a Synthetic and Pharmacopoeia Research Chemical with a niche market.</p>Formula:C17H14F3N3O2SPurity:Min. 95%Molecular weight:381.37 g/molN-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
CAS:<p>N-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine (GW1929) is a potent vasodilator that is used for the treatment of hypertension. It is synthesized by condensation of sodium hydroxide with 2-(4′-chlorophenyl)piperazine followed by methyl esterification and chloride acylation. The synthesis of GW1929 has been accomplished in two steps: carbonate cyclization and valsartan hydrolysis. In the first step, the carboxylic acid group of GW1929 was converted to its corresponding chloride compound which was then reacted with methyl bromide to yield the desired product. The second step involved hydrolysis of GW1929 with potassium carbonate, after which it was oxidized with azide to form an ester. Sodium</p>Formula:C23H27N5O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:421.49 g/molThiamethoxam
CAS:<p>Thiamethoxam ((E)-thiamethoxam) is an insecticide of broad-spectrum neonicotinoids.</p>Formula:C8H10ClN5O3SPurity:>99.99%Color and Shape:SolidMolecular weight:291.716,7,8,9-Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (THPP) is a drug product that belongs to the class of drugs used for research and development. It has been shown to have antiinflammatory properties in animal models. THPP is a metabolite of metoprolol and has been shown to be an impurity of metoprolol. The analytical properties of THPP are not yet known. Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3--yl)-1--piperidinyl]ethyl]-2--methyl--4H--pyrido[1,2--a]pyrimidin--4one</p>Formula:C23H28N4O3Purity:Min. 95%Molecular weight:408.49 g/mol[4-(4-Amino-7-hydroxy-6-methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone
CAS:<p>3-amino-2,6-dimethoxy-4-(4-amino-7-hydroxy-6-methoxyquinazolin-2(1H)-yl)piperazine (DMQA) is a synthetic compound. It is a racemate with two stereoisomers, which are mirror images of each other. The two stereoisomers have been characterized and the data for the two stereoisomers are provided in the table below.</p>Formula:C18H23N5O4Purity:Min. 95%Molecular weight:373.41 g/mol4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid
CAS:<p>4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid (4BMBCA) is a chemical compound that is used as an analytical method in drug discovery and development. It has been shown to have contraceptive properties, which may be due to its ability to inhibit the synthesis of progesterone. 4BMBCA has also been shown to reduce the development of primary tumors in mice. The drug is also able to cause stomatitis and show antimicrobial resistance in humans. Symptoms of this drug include fever, nausea, vomiting, diarrhea, headache, and stomatitis. 4BMBCA has been found by plasma mass spectrometry to be effective against several bacteria types including Staphylococcus aureus and Escherichia coli.</p>Formula:C14H11BrO2Purity:Min. 95%Molecular weight:291.14 g/molBrexpiprazole impurity 3
CAS:<p>Brexpiprazole impurity 3 is a drug product that has been custom synthesized for research purposes. The purity of this product is high and it has been analyzed using analytical methods. This product can be used to study the metabolism of brexpiprazole, which is an atypical antipsychotic medication. Brexpiprazole impurity 3 also has pharmacopoeia standards, which can be used to develop new drugs or as a quality control standard in research and development.</p>Formula:C25H27N3O3SPurity:Min. 95%Molecular weight:449.57 g/molN-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide
CAS:<p>N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide is a metabolite that is formed when the drug product, ticagrelor, undergoes metabolism in the liver. Ticagrelor is a prodrug that requires conversion to its active form, which is N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide, before it can be used as a platelet inhibitor and antiplatelet agent for the prevention of thrombotic events such as heart attack and stroke. It has been shown to have an excellent stability profile and high purity when produced by HPLC or synthesized using the latest methodology under GMP conditions.</p>Purity:Min. 95%Solifenacin impurity C
CAS:<p>Solifenacin impurity C is an impurity that is found in the drug product Solifenacin. It has been shown to be a natural metabolite and has been detected in human urine. Solifenacin impurity C is used as an analytical standard for HPLC analyses of solifenacin, and can also be used as a reference material for pharmacopoeia. The purity of this compound is 99%.</p>Formula:C31H28N2OPurity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:444.57 g/mol4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
CAS:<p>4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one is a drug that has been developed for the treatment of cancer. It is an impurity standard used in HPLC and GC analysis to quantify the concentration of drugs. This compound is a metabolite of the drug carboplatin and can be found in urine as well as other biological fluids. Metabolites are substances produced by metabolism (chemical reactions) in the body. 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one can also be found naturally in plants such as ivy or wild parsnip.</p>Formula:C14H9Cl2NOPurity:Min. 95%Molecular weight:278.13 g/molTopiramate impurity C
CAS:<p>Topiramate impurity C is an analytical reference standard, which is primarily sourced from the chemical synthesis of topiramate-related compounds. With its ability to mimic the structural nuances of impurities found within topiramate formulations, it plays a crucial role in the quality control and validation processes within pharmaceutical development.Being essentially a byproduct or variant of the desired active pharmaceutical ingredient (API), Topiramate impurity C is employed in analytical methodologies to ensure the purity and efficacy of topiramate throughout its manufacturing and storage. Its mode of action involves acting as a comparator or calibrant in quantifying and identifying impurity profiles, thereby facilitating the optimization of synthesis pathways and purification methods.The uses and applications of Topiramate impurity C are integral to the comprehensive quality assurance frameworks in place within pharmaceutical laboratories. It ensures regulatory compliance by adhering to guidelines concerning permissible impurity thresholds, ultimately safeguarding patient safety and therapeutic efficacy. Through high-precision techniques like high-performance liquid chromatography (HPLC) and mass spectrometry, scientists can determine the stability, potency, and purity of pharmaceutical products with accuracy and reliability.</p>Formula:C12H19ClO8SPurity:Min. 95%Molecular weight:358.79 g/mol2-Amino-5,6-dichloro-3,4-dihydroquinazoline hydrobromide
CAS:<p>2-Amino-5,6-dichloro-3,4-dihydroquinazoline hydrobromide is a metabolite of the drug product 2-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)ethylamino]benzeneacetic acid. It has been shown to inhibit protein synthesis in vitro and in vivo.</p>Formula:C8H8BrCl2N3Purity:Min. 95%Molecular weight:296.98 g/molN-[(3-Trifluoromethyl)phenyl)propyl] cinacalcet HCl
CAS:<p>N-[(3-Trifluoromethyl)phenyl)propyl] cinacalcet HCl is an analytical standard that is used as a HPLC impurity standard and an impurity in the synthesis of pharmaceutical drugs. It is also used as a pharmacopoeia reference material for the determination of purity, quality, and identity of drugs. This compound has been assigned a CAS number of 1271930-15-4 (free base). N-[(3-Trifluoromethyl)phenyl] propyl] cinacalcet HCl is one of the metabolites formed from cinacalcet hydrochloride, which is prescribed to treat secondary hyperparathyroidism in postmenopausal women.</p>Formula:C32H31F6N·HClPurity:Min. 95%Molecular weight:580.05 g/molCaptopril EP Impurity H
CAS:<p>Captopril EP Impurity H is a drug product that is used as an analytical reference standard. It is not intended for administration to humans or animals. Captopril EP Impurity H is manufactured by the same process as Captopril, but with a different impurity profile. The purity of this product is 99.5% at 25°C, and it has an impurity profile of less than 0.5%. This product is also known as 4-Amino-N-(2,6-dichlorophenyl)benzenesulfonamide and has CAS No. 205521-07-9.</p>Formula:C15H23NO5S2Purity:Min. 95%Molecular weight:361.48 g/molApixaban Impurity 11
CAS:<p>Apixaban impurity 11 is an analytical standard used in research and development, drug development, and the production of API. It has a purity of 99.5% by HPLC and is a metabolite of apixaban. Apixaban impurity 11 has the CAS number 2204368-51-2 and is a Metabolite and Impurity standard for pharmacopoeia with a purity of 99.5% by HPLC. This product can be custom synthesized or natural with a purity of 99.5% by HPLC.</p>Formula:C29H31N5O5Purity:Min. 95%Molecular weight:529.59 g/molO-De(3-fluorobenzyl) lapatinib ditosylate
CAS:<p>O-De(3-fluorobenzyl) lapatinib ditosylate (OFLB) is a drug product that is supplied as a white to light yellow crystalline powder. It has been custom synthesized for the purpose of drug development and research. OFLB is an analytical standard and metabolite, which will be used in metabolism studies. This product is not intended for use in humans or animals.</p>Formula:C22H21ClN4O4S•(C7H8O3S)2Purity:Min. 95%Molecular weight:817.35 g/mol2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
CAS:<p>2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a synthetic, impurity standard that is used in the synthesis of drug products. It has been shown to inhibit the metabolism of drugs and may be used as a marker for drug metabolism. This compound may also be used as a marker in analytical studies to assess the purity of a drug product. 2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole has not been evaluated for safety or efficacy.</p>Formula:C15H15N3O2SPurity:Min. 95%Molecular weight:301.36 g/molDefluoropitavastatin calcium Salt
CAS:<p>Defluoropitavastatin calcium salt is a synthetic, high purity, pharmacopoeia drug product. It is a metabolite of pitavastatin and has been shown to have similar pharmacological activity. Defluoropitavastatin calcium salt has a niche in the analytical industry due to its high purity and stability. It has been used as an impurity standard for HPLC analysis. Defluoropitavastatin calcium salt is not found in nature and can be synthesized with the help of our Custom Synthesis service.</p>Purity:Min. 95%(1RS)-1-(6-Methoxy-2-naphthyl)ethanol
CAS:<p>(1RS)-1-(6-Methoxy-2-naphthyl)ethanol is a multiphase test drug that exhibits reactive properties. It reacts with hydrogen to form hydrogen bonds and is insensitive to sephadex g-100. This compound also forms hydrogen bond with acetyl groups, which can be observed in the strain of the molecule. (1RS)-1-(6-Methoxy-2-naphthyl)ethanol has a primary alcohol group and can be easily acetylated. UV irradiation causes this compound to fluoresce, making it useful in kinetic studies.</p>Formula:C13H14O2Purity:Min. 95%Molecular weight:202.25 g/mol2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid hydrobromide
CAS:<p>2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid hydrobromide is a drug product that is Custom synthesized. It has a high purity and analytical quality. Metabolism studies have been conducted on this compound. Natural and synthetic sources are available for this compound. It is found in the Drug Development section of the pharmacopoeia. The CAS number for this compound is 1194434-39-3, and it has an Impurity Standard as well as an HPLC standard.</p>Formula:C10H10BrCl2N3O2Purity:Min. 95%Molecular weight:355.02 g/molPantoprazole N-oxide
CAS:<p>Pantoprazole is a proton pump inhibitor that inhibits the gastric acid secretion by blocking the hydrogen/potassium ATPase enzyme in the stomach. Pantoprazole N-oxide, a prodrug of pantoprazole, is converted to pantoprazole after administration and has been shown to be more stable than pantoprazole. It has been shown to have tissue-specific effects, with high concentrations found in gastrointestinal tissues such as the abomasum, ileum, and colon. Pantoprazole N-oxide is also found in plasma samples at low levels. This drug may be useful for ulceration because it prevents heartburn caused by excess stomach acid.</p>Formula:C16H15F2N3O5SPurity:Min. 95%Color and Shape:PowderMolecular weight:399.37 g/mol3-[2-[4-(1,2-Benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>3-[2-[4-(1,2-Benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is an analog of the antibacterial drug cefuroxime. It has been shown to be a potent inhibitor of bacterial DNA gyrase and topoisomerase IV. This compound has been shown to have a greater degree of activity against Gram Positive bacteria than Gram Negative bacteria in vitro. 3-[2-[4-(1,2-Benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-- 2 -methyl-- 4H-- pyrido[1,2-- a]pyrimidin-- 4 -one is not active against acid</p>Formula:C23H28N4O2Purity:Min. 95%Molecular weight:392.49 g/mol4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride
CAS:<p>4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride is a synthetic drug product that has been purified to high purity. This compound is used as an analytical standard and impurity in the development of drugs. 4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride is a metabolite of imidazole, which is a natural substance with unknown pharmacological activity. It has been found to be an impurity in the synthesis of various pharmaceuticals, including metronidazole and ampicillin. This product has not yet been evaluated for safety or efficacy in humans.</p>Formula:C7H13N3S·2HClPurity:Min. 95%Molecular weight:244.19 g/molα-Desmethyl anastrozole
CAS:<p>Alpha-Desmethyl anastrozole is a synthetic chemical that has been used as an impurity standard for the drug product, Anastrozole (Arimidex). This compound is metabolized in humans and is a metabolite of Arimidex. Alpha-Desmethyl anastrozole exhibits high purity and can be synthesized using custom synthesis. The CAS number for this compound is 1215780-15-6.</p>Formula:C16H17N5Purity:Min. 95%Molecular weight:279.34 g/molIsopropyl 2-(3-nitrobenzilidene)acetoacetate
CAS:<p>This isopropyl 2-(3-nitrobenzylidene)acetoacetate is a reaction solution that can be used to produce the antihypertensive drug, methyldopa. The reaction time required for this solution to react is about two hours. This product also contains chloride and calcium antagonist, which are added as catalysts. The rate of this reaction depends on the temperature and concentration of organic solvent. Crotonic acid, dihedral, and the yield of this reaction depend on the purity of reagents. Impurities in this product include isobutyl and methylbenzene, but these are not harmful to human health. This product also contains piperazine and thionyl chloride as impurities.</p>Formula:C14H15NO5Purity:Min. 95%Molecular weight:277.27 g/molN-Hydroxy-6-(trifluoromethoxy)-2-benzothiazolamine
CAS:<p>N-Hydroxy-6-(trifluoromethoxy)-2-benzothiazolamine (NHTB) is a drug that has been shown to have clinical use as an anticonvulsant. NHTB is a metabolite of diazepam, which is used to treat seizures and anxiety. It binds to the GABA receptor and increases the duration of time that the chloride channel remains open, leading to inhibition of neural activity and in turn seizure control. NHTB has been found to be more potent than diazepam and has also been shown to bind to other receptors, such as dopamine receptors.</p>Formula:C8H5F3N2O2SPurity:Min. 95%Molecular weight:250.2 g/molValdecoxib impurity I
CAS:<p>Valdecoxib impurity I is a synthetic compound that is used as an impurity standard for the drug product Valdecoxib. It has a CAS number of 1373038-59-5 and is used in HPLC analysis to detect the presence of metabolites. Valdecoxib impurity I has been shown to be a metabolite of Valdecoxib, but the metabolic pathway has not been elucidated.</p>Formula:C16H15N3O5S2Purity:Min. 95%Molecular weight:393.44 g/molTadalafil spiro-urethane impurity (EP impurity F)
CAS:<p>Please enquire for more information about Tadalafil spiro-urethane impurity (EP impurity F) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C22H19N3O6Purity:Min. 95%Molecular weight:421.4 g/mola-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-propyl-benzeneacetonitrile
CAS:<p>a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-propyl-benzeneacetonitrile is a drug product that is custom synthesized and has been shown to have high purity. It is also used in analytical studies, metabolism studies, and natural drug development. This compound can also be found as an impurity standard for HPLC or as an API impurity.</p>Formula:C27H38N2O4Purity:Min. 95%Molecular weight:454.6 g/mol[6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone
CAS:<p>6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone is a synthetic impurity standard that is used as a reference material in the analytical, natural and drug development, and metabolite studies. 6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone has a molecular weight of 390.27 and chemical formula C26H28N2O3S. It is also referred to by its CAS number 1391054-73-1.6</p>Formula:C28H27NO4SPurity:Min. 95%Molecular weight:473.58 g/mol3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide
CAS:<p>3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide is an impurity found in the drug product of 3'-acetyl-4'-(2,3-epoxypropoxy)butyranilide hydrochloride. It has a molecular weight of 268.9 and chemical formula C12H18O6N2. 3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide is a synthetic compound that can be used as an analytical reference material for HPLC standardization or as an impurity standard for synthesis.</p>Formula:C15H19NO4Purity:Min. 95%Molecular weight:277.32 g/molAlverine EP Impurity E
CAS:<p>Alverine EP Impurity E is a nitrogen containing compound with the molecular formula C9H10N. It has been shown to be an ionophore, which means that it can transport ions across a membrane. Alverine EP Impurity E is stabilized by alkali and buffered with a pH range of 7-8. The response time for this compound is linear and its contact time ranges from 1-12 hours. This impurity has a phenyl group and a ph range of 6-7. It reacts with electrodes in an electrical field, forming an electric current when it comes into contact with the electrodes. The nitrogen atom in Alverine EP Impurity E is bonded to two carbon atoms and one hydrogen atom.</p>Formula:C27H33NPurity:Min. 95%Molecular weight:371.56 g/molDesdifluoromethoxy hydroxy pantoprazole
CAS:<p>Desdifluoromethoxy hydroxy pantoprazole is a synthetic compound that is used as an impurity standard for the drug product Pantoprazole. It has a purity of ≥98% and is stable under ambient conditions. Desdifluoromethoxy hydroxy pantoprazole is not active on its own, but it is a metabolite of pantoprazole. It can be used to study the metabolism of pantoprazole.</p>Formula:C15H15N3O4SPurity:Min. 95%Molecular weight:333.36 g/mol
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