Enzyme Modulators
Enzyme modulators are compounds that can enhance or inhibit the activity of enzymes, thereby regulating the rate of biochemical reactions. These modulators play a critical role in controlling metabolic pathways, cell signaling, and various physiological processes. Enzyme modulators are widely used in research and drug development to study enzyme functions and to develop therapeutic agents. At CymitQuimica, we offer a comprehensive range of high-quality enzyme modulators to support your research in enzyme regulation and drug discovery.
Subcategories of "Enzyme Modulators"
Found 690 products for "Enzyme Modulators". Showing the first 500.
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Lumiracoxib - Bio-X ™
CAS:Controlled ProductLumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug that is used for the treatment of osteoarthritis. This drug inhibits prostaglandin synthesis via inhibition of COX-2.Formula:C15H13ClFNO2Purity:Min. 95%Color and Shape:PowderMolecular weight:293.72 g/molDovitinib base
CAS:Receptor tyrosine kinase inhibitor; anti-angiogenesis; anti-oncogenesisFormula:C21H21FN6OPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:392.43 g/molAfatinib - Bio-X ™
CAS:Afatinib is a small molecule that inhibits the activity of cellular kinases that are involved in the progression of cancer. It is an Irreversible inhibitor of three members of the ErbB family. This molecule binds covalently to cysteine 797 residue in HER2 and blocks downstream cellular signalling which inhibits cellular growth and promotes apoptosis. It has been researched for the treatment of non-small cell lung cancer (NSCLC), breast cancer, pancreatic cancer and colorectal cancer.Formula:C24H25ClFN5O3Purity:Min. 95%Color and Shape:PowderMolecular weight:485.94 g/molCamostat mesylate - Bio-X ™
CAS:Camostat is a serine protease inhibitor that is used for the treatment of chronic pancreatitis. This drug has shown to reduce inflammation and pain. Studies have shown that Camostat has also inhibited the entry of SARS-CoV-2 in lung cells by inhibiting the priming process of S-protein, necessary for the viral entry into host cells.Formula:C20H22N4O5•CH4O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:494.52 g/molLOXO-305
CAS:LOXO-305 is a small molecule inhibitor, which is a synthesized chemical compound designed to selectively target specific enzymes or pathways. Its source is rooted in medicinal chemistry and pharmacological research aimed at elucidating pathways involved in oncogenesis.
Formula:C22H21F4N5O3Purity:Min. 95%Color and Shape:PowderMolecular weight:479.43 g/molR-(-)-Arundic acid
CAS:R-(-)-Arundic acid is a chiral compound, which is a derivative of arundic acid specifically designed for enantiomeric purity. It is sourced through synthetic organic chemistry processes, allowing for precise control over its stereochemistry. The mode of action of R-(-)-Arundic acid involves the inhibition of astrocyte activation by modulating the synthesis of certain cytokines and inflammatory mediators. This mechanism provides a neuroprotective effect, making it a valuable tool in the study of neurodegenerative diseases and brain injuries.
Formula:C11H22O2Purity:Min. 98 Area-%Color and Shape:Clear Viscous LiquidMolecular weight:186.29 g/molAnastrozole - Bio-X ™
CAS:Controlled ProductAnastrozole is a non-steroidal drug that belongs to the class of aromatase inhibitors. It inhibits the production of estrogen by blocking the conversion of androgens to estrogens in peripheral tissues. The drug has been shown to be effective in treating breast cancer in postmenopausal women. In vitro assays have shown that Anastrozole can inhibit tumor growth as well as induce apoptosis in human serum cells, which suggests that it may be effective against a variety of cancers.
Formula:C17H19N5Purity:Min. 95%Color and Shape:PowderMolecular weight:293.37 g/molBrivanib alaninate
CAS:VEGFR2 a tyrosine kinase receptor inhibitor; antineoplasticFormula:C22H24FN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:441.18123Ulixertinib
CAS:Inhibitor of ERK1 and ERK2 kinasesFormula:C21H22Cl2N4O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:433.33 g/molGefitinib hydrochloride
CAS:RIPK2 protein kinase inhibitor; EGFR inhibitorFormula:C22H24ClFN4O3·HClPurity:Min. 95%Color and Shape:PowderMolecular weight:483.36 g/molCrenolanib
CAS:Inhibits type III tyrosine kinases (PDGFRα, PDGFRβ, FLT3)Formula:C26H29N5O2Purity:Min. 95%Color and Shape:White To Yellow SolidMolecular weight:443.54 g/molBMS 754807
CAS:A reversible inhibitor of IGF-1R kinase and insulin receptor. Has anti-growth effects in mesenchymal, epithelial and hematopoietic tumor types. Synergistic with other cytotoxic, hormonal and targeted anti-cancer therapy.
Formula:C23H24FN9OPurity:Min. 95%Color and Shape:PowderMolecular weight:461.49 g/molAceclofenac - Bio-X ™
CAS:Acecelofenac is a non-steroidal anti-inflammatory drug that is used in the treatment of osteoarthritis, arthritis, and ankylosing spondylitis. This drug is also a cyclooxygenase inhibitor and works by inhibiting this enzyme so that pain and inflammation is reduced.Formula:C16H13Cl2NO4Purity:Min. 95%Color and Shape:PowderMolecular weight:354.18 g/molSivelestat
CAS:Inhibitor of human neutrophil elastase
Formula:C20H22N2O7SPurity:Min. 95%Molecular weight:434.46 g/molMGCD 265
CAS:Inhibits MET, VEGFR1-3, Tie and Ron tyrosine kinases; antineoplasticFormula:C26H20FN5O2S2Purity:Min. 95%Molecular weight:517.60 g/molThioglycosyl Naphthalimide
CAS:Thioglycosyl Naphthalimide is a highly potent human O-GlcNAcase (hOGA) inhibitor with good selectivity against human β-N-acetylhexosaminidase B (HsHexB).Formula:C30H40N4O7SPurity:Min. 95%Molecular weight:600.73 g/molXMU MP 2
CAS:BRK tyrosine kinase (PTK6) inhibitor; anti-proliferative in breast cancer cells
Formula:C32H33F3N8O2Purity:Min. 95%Color and Shape:PowderMolecular weight:618.65 g/molCZC 25146
CAS:Inhibitor of leucine-rich repeat kinase LRRK2Â
Formula:C22H25FN6O4SPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:488.54 g/molMRK 560
CAS:γ-secretase inhibitor; reduces amyloid-β in brainÂ
Formula:C19H17ClF5NO4S2Purity:Min. 95%Molecular weight:517.92 g/molGNE 6776
CAS:Specific inhibitor of the ubiquitin specific protease-7 (USP7), which is a validated deubiquitinase of the E3 ubiquitin-protein ligase MDM2. The compound inhibits the USP7 deubiquitinase activity by binding to acidic amino acid residues important for the interaction with ubiquitin. Induces tumor cell death and enhances cytotoxicity of chemotherapeutic agents.Formula:C20H20N4O2Purity:Min. 95%Molecular weight:348.4 g/molIdelalisib
CAS:Idelalisib is a pharmaceutical drug that functions as a PI3Kδ inhibitor, developed through synthetic chemical processes. Its mode of action involves selectively targeting and inhibiting phosphatidylinositol 3-kinase delta (PI3Kδ), a lipid kinase that plays a crucial role in the signaling pathways responsible for cell proliferation, survival, and differentiation. By inhibiting this enzyme, Idelalisib effectively impedes pathways that are often hyperactivated in certain hematologic malignancies, thereby exerting antitumor effects.Formula:C22H18FN7OPurity:Min. 95%Color and Shape:PowderMolecular weight:415.42 g/molSRT1720 hydrochloride
CAS:SIRT1 activatorFormula:C25H23N7OS·xHClPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:469.56 g/molAG 221
CAS:Inhibitor of isocitrate dehydrogenase 2Formula:C19H17F6N7OPurity:Min. 95%Color and Shape:PowderMolecular weight:473.38 g/molDCC 2036
CAS:Inhibits multiple tyrosine kinases (Abl1, Src family kinases, Tie-2 and VEGFR-2)Formula:C30H28FN7O3Purity:Min. 95%Color and Shape:PowderMolecular weight:553.59 g/molPeiminine
CAS:Inhibitor of TGF-α, CTGF, ERK1/2, NF-κB and FasL; anti-inflammatoryFormula:C27H43NO3Purity:Min. 98 Area-%Molecular weight:429.64 g/molSGC AAK1 1
CAS:Dual inhibitor of the adaptor protein 2-associated kinase 1 (AAK1) and BMP2-inducible kinase (BMP2K) with IC50 values of 270 nM and 1 μM, respectively. In a recent study, SGC AAK1 1 stabilised β-catenin, inhibited phosphorylation of the AP2 complex subunit mu protein (AP2M1) and activated Wnt signalling in in vitro experiments._x000D_Formula:C21H25N5O3SPurity:Min. 95%Color and Shape:SolidMolecular weight:427.52 g/molEbselen
CAS:Ebselen is a non-toxic organoselenium compound with antioxidant, anti-inflammatory and cytoprotective properties. Ebselen is an inhibitor of lipoxygenases, nitric oxide (NO) synthases, protein kinase C, H+/K+-ATPase, thioredoxin reductase and NADPH oxidase. Recently, ebselen has been identified by several studies as a covalent inhibitor of the main protease Mpro from coronaviruses. For the SARS-CoV-2 main protease Mpro, the IC50 value is 0.67 μM and EC50 is 4.57 μM.Formula:C13H9NOSePurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:274.18 g/molMinaprine dihydrochloride
CAS:Controlled ProductShort acting monoamine oxidase inhibitor
Formula:C17H22N4O•(HCl)2Purity:Min. 95%Color and Shape:PowderMolecular weight:371.3 g/molLY 2886721
CAS:Inhibitor of BACE1 proteaseFormula:C18H16F2N4O2SPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:390.41 g/molZileuton- Bio-X ™
CAS:Zileuton is an inhibitor of the 5-lipoxygenase enzyme, thus preventing the leukotrienes LTE4, LDT4, LTB4 and LTC4 from being formed. This in turn reduces inflammation, bronchoconstriction and mucus secretion in the airways. As a result, Zileuton can be used in the treatment and management of asthma and allergic rhinitis. Studies have shown that Zileuton has the potential to reverse dementia-related brain damage.Formula:C11H12N2O2SPurity:(%) Min. 95%Color and Shape:PowderMolecular weight:236.29 g/molMalotilate - Bio-X ™
CAS:Malotilate is a pharmacological agent that is used to treat symptoms of hepatitis, bowel disease, and collagen diseases. This drug reduces collagen synthesis and cell migration activity of fibroblasts in vitro. It also has been shown to facilitate liver regeneration in rats.Formula:C12H16O4S2Purity:(%) Min. 95%Color and Shape:PowderMolecular weight:288.39 g/molKenpaullone
CAS:Inhibitor of glycogen synthase 3 (GSK-3) and cyclin-dependent kinases CDK1, CDK2 and CDK5. Kenpaullone can substitute transcription factor Klf4 in reprogramming of fibroblast to induced pluripotent stem cells when using the method of ectopic expression of transcriptional factors. In an in vitro model for Alzheimer’s disease, kenpaullone decreased production of amyloid beta peptides Aβ40 and Aβ42.
Formula:C16H11BrN2OPurity:Min. 95%Color and Shape:Yellow To Dark Yellow SolidMolecular weight:326.00548GSK 2606414
CAS:Inhibitor of EIF2AK3/PERK kinasesFormula:C24H20F3N5OPurity:Min. 95%Color and Shape:PowderMolecular weight:451.44 g/mol(S)-Mephenytoin - Bio-X ™
CAS:(S)-Mephenytoin is a substrate of cytochrome P450 enzyme CYP2C19 (a hydroxylase). It is an effective anticonvulsant that improves control of seizures in patients. According to studies, the drug exhibits a genetic polymorphism in CYP2C19 that results in reduced metabolism in some individuals.Formula:C12H14N2O2Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:218.25 g/molCA3
CAS:Inhibits YAP/Tead transcriptional activity. Has anti-tumour effects on oesophageal adenocarcinoma with therapeutic potential in combination with 5-FU. Involved in ferroptosis, mediated by iron-dependent ROS.
Formula:C23H27N3O5S2Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:489.61 g/molEtodolac - Bio-X ™
CAS:Etodolac is a non-steroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis and rheumatoid arthritis. It is also used to treat acute pain. This drug works by inhibiting prostaglandin synthesis from the inhibition of the enzyme cyclooxygenase.Formula:C17H21NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:287.35 g/molDMAT
CAS:Inhibitor of protein kinase CK2
Formula:C9H7Br4N3Purity:Min. 95%Color and Shape:White PowderMolecular weight:476.79 g/mol6-Thioguanine - Bio-X ™
CAS:6-Thioguanine is a purine analog used in the therapy for leukemia and for remission consolidation in patients with acute nonlymphocytic anemia. This drug also has antimetabolite action. It replaces guanine during DNA replication. This substitution disrupts the accurate pairing of DNA bases, leading to errors in DNA replication and hinders cell division.Formula:C5H5N5SPurity:Min. 95%Color and Shape:PowderMolecular weight:167.19 g/molML 210
CAS:Inhibitor of glutathione peroxidase GPX4Formula:C22H20Cl2N4O4Purity:Min. 95%Color and Shape:SolidMolecular weight:475.32 g/molTriptolide
CAS:Inhibits RNAPII-mediated trasncription; immunosuppressant; anti-inflammatoryFormula:C20H24O6Purity:Min. 97 Area-%Color and Shape:PowderMolecular weight:360.4 g/molBRD 6989
CAS:A small molecule inhibitor with high selectivity for CDK8 over CDK19. Increases IL-10 production in stimulated human and murine macrophages and dendritic cells. Modulatory action on inflammatory responses has therapeutic potential.Formula:C16H16N4Purity:Min. 95%Color and Shape:SolidMolecular weight:264.33 g/molA 769662
CAS:Allosteric activator of AMP-activated protein kinase (AMPK) acting on the AMPK-β subunit with therapeutic potential in metabolic disorders such as diabetes, obesity, etc. A769662 also blocks the differentiation of mouse embryonic stem cells (mESCs) and maintains the mESCs in naïve state even in the absence of leukemia inhibitory factor (2i/L).Formula:C20H12N2O3SPurity:Min. 95%Color and Shape:SolidMolecular weight:360.39 g/molTacrolimus - Bio-X ™
CAS:Tacrolimus is a calcineurin inhibitor drug that is used for the prevention of rejection after an organ transplant. This drug can also be used in the treatment of severe atopic dermatitis. Tacrolimus’ mechanism of action is not well known however it is understood that this drug inhibits T-lymphocyte activation by binding to an intracellular protein called FKBP-12. This drug also has anti-inflammatory properties.
Formula:C44H69NO12Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:804.02 g/molAZD 9291
CAS:A potent inhibitor of EGFR with sensitizing and T790M resistance mutations, selective over the wild-type form of the receptor. Causes tumour regression in EGFR mutant T790M transgenic and xenograft models in vivo.Formula:C28H33N7O2Purity:Min. 97%Color and Shape:SolidMolecular weight:499.61 g/molRamipril - Bio-X ™
CAS:Ramipril is an angiotensin-converting enzyme (ACE) inhibitor. It is used in the treatment of high blood pressure, congestive heart failure and other cardiovascular diseases. Ramipril inhibits the conversion of angiotensin I to angiotensin II by blocking ACE, which lowers blood pressure and reduces fluid retention.This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C23H32N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:416.51 g/molR-Rolipram
CAS:Inhibitor of PDE4 enzyme; anti-inflammatory
Formula:C16H21NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:275.34 g/molAcalabrutinib
CAS:Inhibitor of the Bruton tyrosine kinase
Formula:C26H23N7O2Purity:Min. 98 Area-%Color and Shape:SolidMolecular weight:465.51 g/molFeprazone
CAS:Anti-inflammatory; inducer of P450 II B familyFormula:C20H20N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:320.39 g/molRucaparib camsylate
CAS:Inhibitor of poly (ADP-ribose) polymerase enzyme; antineoplasticFormula:C19H18FN3O•C10H16O4SPurity:Min. 95%Color and Shape:Off-White To Yellow SolidMolecular weight:555.66 g/mol
