Enzyme Modulators
Subcategories of "Enzyme Modulators"
Found 691 products for "Enzyme Modulators".
Danusertib
CAS:Inhibitor of aurora kinases
Formula:C26H30N6O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:474.57 g/molK252c
CAS:Inhibitor of protein kinase PKCFormula:C20H13N3OPurity:Min. 95%Color and Shape:PowderMolecular weight:311.34 g/molPemetrexed disodium salt - Bio-X ™
CAS:Pemetrexed is an antifolate drug that is used to treat mesothelioma and non-small cell lung cancer. It is used during chemotherapy and sometimes used in conjunction with cisplatin. This drug disrupts folate-dependent metabolic activities essential for cell replication. In vitro studies have shown that Pemetrexed inhibits thymidylate synthase.Formula:C20H19N5Na2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:471.37 g/molMoexipril HCl - Bio-X ™
CAS:Moexipril is an angiotensin converting enzyme inhibitor that is used for the treatment of hypertension. This drug is a prodrug for moexiprilat and works by relaxing the blood vessels causing them to widen and lowering blood pressure. Moexipril has been shown to be effective in treating metabolic disorders such as congestive heart failure.Formula:C27H34N2O7Purity:Min. 95%Color and Shape:PowderMolecular weight:498.57 g/molBaricitinib
CAS:Baricitinib is a Janus kinase inhibitor (JAK) currently used as monotherapy in the treatment of rheumatoid arthritis. Barictinib is also recommened for the treatment of atopic dermatitis and systemic lupus erythematosus. In mice interestingly, the administration of baricitinib reduced the inflammatory effects induced by a high-sugar diet on the metabolism.Formula:C16H17N7O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:371.42 g/molPazopanib - Bio-X ™
CAS:Pazopanib is an antineoplastic agent that is used to treat advanced renal cell cancer and advanced soft tissues sarcoma. This drug is a multitargeted tyrosine kinase inhibitor against vascular endothelial growth factor receptor 1, 2, 3 and c-kit. As a result, it increases tumor apoptosis and decreases tumor blood flow.
Formula:C21H23N7O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:437.52 g/molCobimetinib
CAS:Inhibitor of MEK kinase
Formula:C21H21F3IN3O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:531.31 g/molVandetanib - Bio-X ™
CAS:Vandetanib is antineoplastic kinase inhibitor that binds to the ATP-binding site of the enzyme squamous cell carcinoma kinase (SQSTM1). This binding inhibits the phosphorylation of the Bcl-2 protein and causes apoptosis. Vandetanib has been shown to have an effect on polymerase chain reaction amplification, terminal erythrocyte differentiation, and on gene expression in human tissue.Formula:C22H24BrFN4O2Purity:Min. 95%Color and Shape:PowderMolecular weight:475.35 g/molSunitinib malate - Bio-X ™
CAS:Sunitinib is a receptor tyrosine kinase inhibitor and a chemotherapeutic agent used for the treatment of renal cell carcinoma. This drug can also be used to treat gastrointestinal tumors that are resistant to imatinib. Sunitinib inhibits VEGFR1, VEGFR2, VEGFR3, PDGFR and KIT tyrosine kinases.Formula:C22H27FN4O2·C4H6O5Purity:Min. 95%Color and Shape:PowderMolecular weight:532.56 g/molEAI045
CAS:Inhibitor of EGFR receptor
Formula:C19H14FN3O3SPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:383.4 g/mol(-)-Huperzine A
CAS:Acetylcholinesterase inhibitor; therapy for Alzheimer's diseaseFormula:C15H18N2OPurity:(%) Min. 98%Color and Shape:PowderMolecular weight:242.32 g/molPimasertib
CAS:A selective inhibitor of MEK1/2 kinase. Anti-proliferative and pro-apoptotic in multiple myeloma (MM) cells via G0/G1 cell cycle arrest and caspase 3 and PARP cleavage, respectively. Synergistic with other anti-MM therapies. Has anti-tumor effects in some solid tumors, such as in K-ras mutated colorectal cancer.Formula:C15H15FIN3O3Purity:Min. 95%Color and Shape:White To Yellow SolidMolecular weight:431.2 g/molCP 43
CAS:Inhibitor of TAOK1 and TAOK2 kinasesFormula:C25H24N2O2Purity:Min. 95%Color and Shape:SolidMolecular weight:384.47 g/molDexrazoxane - Bio-X ™
CAS:Dexrazoxane is a cytoprotective drug that is used in chemotherapy to provide cardio-protection against anthracycline toxicity. It is an antimitotic agent with immunosuppressive properties. Dexrazoxane works by binding to iron in the cell, preventing it from being released. Dexrazoxane is also a catalytic inhibitor of topoisomerase II.Formula:C11H16N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:268.27 g/molGC376 sodium
CAS:GC 376 is an inhibitor of the main protease Mpro (3CLpro) in coronaviruses as well as picornaviruses. This broad-spectrum antiviral compound has been used as investigational veterinary drug for treatment of feline infectious peritonitis virus (FIPV) infections. Recent studies also showed that GC 376 inhibits the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.03 μM and EC50 of 3.37 μM.
Formula:C21H30N3NaO8SPurity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:507.53 g/molD 4476
CAS:Inhibitor of protein kinase CK1Formula:C23H18N4O3Purity:Min. 95%Molecular weight:398.41 g/molRucaparib
CAS:Inhibitor of poly (ADP-ribose) polymerase enzyme; antineoplastic
Formula:C19H18FN3OPurity:Min. 98 Area-%Color and Shape:Yellow PowderMolecular weight:323.36 g/molCarbimazole - Bio-X ™
CAS:Carbimazole is an imidazole antithyroid agent that is used to treat hyperthyroidism. It reduces the production of diiodotyrosine and thyroxine, as well as the uptake and concentration of inorganic iodine by the thyroid. Once it has been converted to methimazole, the thyroid peroxidase enzyme is inhibited from coupling and iodinating the tyrosine residues on thyroglobulin therefore lowering the production of the thyroid hormones T3 and T4.
Formula:C7H10N2O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:186.23 g/molBivalirudin
CAS:Selectively inhibits α- and ζ-thrombins and elicits procoagulant effects. Reduces platelet deposition in a rat carotid endarterectomy model. Has therapeutic potential as an anti-thrombotic agent in patients with heparin-associated thrombosis.
Formula:C98H138N24O33Purity:Min. 95%Color and Shape:White SolidMolecular weight:2178.98581Rolipram
CAS:Inhibitor of PDE4 enzyme; anti-inflammatory
Formula:C16H21NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:275.34 g/mol
