Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(166 products)
- Bcr-Abl(117 products)
- EGFR(572 products)
- FAK(72 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(178 products)
- JAK(244 products)
- PDGFR(127 products)
- RAAS(86 products)
- Src(82 products)
- Syk(37 products)
- Thrombin(56 products)
- VDA(2 products)
- VEGFR(239 products)
Show 6 more subcategories
Found 2344 products of "Angiogenesis"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
D4476
CAS:D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).Formula:C23H18N4O3Purity:99.7% - 99.96%Color and Shape:SolidMolecular weight:398.41BI-4020
CAS:BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.Formula:C30H38N8O2Purity:97.21% - >99.99%Color and Shape:SolidMolecular weight:542.68Ref: TM-T10534
1mg161.00€5mg376.00€10mg538.00€25mg803.00€50mg1,071.00€100mg1,431.00€200mg1,953.00€1mL*10mM (DMSO)447.00€WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formula:C17H14BrN3OPurity:98.92% - 99.73%Color and Shape:SolidMolecular weight:356.22Futibatinib
CAS:Futibatinib (TAS-120) is an orally active, potent,and irreversible FGFR inhibitor of FGFR1, FGFR2, FGFR3, and FGFR4.Cost-effective and quality-assured.Formula:C22H22N6O3Purity:97.66% - 99.44%Color and Shape:SolidMolecular weight:418.45Ref: TM-T5044
1mg50.00€5mg114.00€10mg167.00€25mg313.00€50mg485.00€100mg627.00€200mg890.00€1mL*10mM (DMSO)127.00€2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.Formula:C16H13Cl2N3O2Purity:98.77%Color and Shape:SolidMolecular weight:350.2CH5424802 analog
CAS:CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.Formula:C28H30N4O2Purity:98.96%Color and Shape:SolidMolecular weight:454.56Ref: TM-T9224
1mg124.00€5mg271.00€10mg408.00€25mg672.00€50mg945.00€100mg1,279.00€1mL*10mM (DMSO)324.00€RO495
CAS:RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assaysFormula:C17H14Cl2N6OPurity:97.94%Color and Shape:SolidMolecular weight:389.24Ref: TM-T22416
1mg46.00€5mg86.00€10mg126.00€25mg235.00€50mg344.00€100mg465.00€200mg625.00€1mL*10mM (DMSO)94.00€Orantinib
CAS:Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35AZD-1480
CAS:AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in solid tumors, PPV, PMF, ET trials.Formula:C14H14ClFN8Purity:98.25% - 99.47%Color and Shape:SolidMolecular weight:348.77GNF-5
CAS:GNF-5, non-ATP Bcr-Abl inhibitor (IC50: 0.22±0.1 uM, wild-type), improves upon GNF-2 with better pharmacokinetics.Formula:C20H17F3N4O3Purity:98% - 99.94%Color and Shape:SolidMolecular weight:418.37CEP-28122
CAS:CEP-28122 is a highly potent and selective orally active ALK inhibitor.Formula:C28H35ClN6O3Purity:99.87% - >99.99%Color and Shape:SolidMolecular weight:539.07Baricitinib phosphate
CAS:Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.Formula:C16H20N7O6PSPurity:99.4% - 99.91%Color and Shape:SolidMolecular weight:469.41Ref: TM-T2360
5mg40.00€10mg52.00€25mg73.00€50mg93.00€100mg105.00€200mg157.00€500mg260.00€1mL*10mM (DMSO)46.00€SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurity:99.56%Color and Shape:SolidMolecular weight:336.15Ref: TM-T8719
1mg43.00€5mg87.00€10mg133.00€25mg227.00€50mg344.00€100mg429.00€200mg597.00€1mL*10mM (DMSO)94.00€S49076 HCl
CAS:S49076 HCl (S-49076 Hydrochloride) is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3.Formula:C22H18ClN3O5Purity:98%Color and Shape:SolidMolecular weight:439.85Remibrutinib
CAS:Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.Formula:C27H27F2N5O3Purity:99.5% - 99.81%Color and Shape:SolidMolecular weight:507.53Ref: TM-T16730
1mg92.00€5mg210.00€10mg340.00€25mg572.00€50mg713.00€100mg1,099.00€200mg1,485.00€1mL*10mM (DMSO)235.00€Itacitinib
CAS:Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.Formula:C26H23F4N9OPurity:96.4% - 99.5%Color and Shape:SolidMolecular weight:553.51Oclacitinib maleate
CAS:Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.Formula:C15H23N5O2S·C4H4O4Purity:99.17% - 99.92%Color and Shape:SolidMolecular weight:453.51Ref: TM-T6914
1mg37.00€2mg52.00€5mg74.00€10mg94.00€25mg166.00€50mg258.00€100mg432.00€1mL*10mM (DMSO)81.00€Ruxolitinib
CAS:Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.Formula:C17H18N6Purity:99.4% - >99.99%Color and Shape:SolidMolecular weight:306.36Ref: TM-T1829
5mg55.00€10mg71.00€25mg96.00€50mg110.00€100mg146.00€200mg231.00€500mg393.00€1mL*10mM (DMSO)62.00€JAK-IN-5 hydrochloride
CAS:JAK-IN-5 hydrochloride is a JAK inhibitor [1].Formula:C27H32ClFN6OColor and Shape:SolidMolecular weight:511.03Tofacitinib Citrate
CAS:Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).Formula:C22H28N6O8Purity:99.19% - 99.75%Color and Shape:SolidMolecular weight:504.49LDN193189
CAS:LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.Formula:C25H22N6Purity:98% - 99.86%Color and Shape:SolidMolecular weight:406.48Vodobatinib
CAS:Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.Formula:C27H20ClN3O2Purity:99.06% - 99.55%Color and Shape:SolidMolecular weight:453.92Ref: TM-T8882
1mg34.00€5mg74.00€10mg110.00€25mg200.00€50mg323.00€100mg500.00€500mg1,209.00€1mL*10mM (DMSO)82.00€Upadacitinib
CAS:Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.Formula:C17H19F3N6OPurity:98.96% - 99.94%Color and Shape:SolidMolecular weight:380.37Ref: TM-T7503
2mg55.00€5mg89.00€10mg116.00€25mg198.00€50mg276.00€100mg389.00€200mg595.00€1mL*10mM (DMSO)44.00€Nilotinib monohydrochloride monohydrate
CAS:Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosineFormula:C28H22F3N7O·HCl·H2OPurity:99.93%Color and Shape:SolidMolecular weight:583.99Belizatinib
CAS:Belizatinib (TSR-011) is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant ALK) and TRKA, TRKB, and TRKC.Formula:C33H44FN5O3Purity:99.33% - 99.44%Color and Shape:SolidMolecular weight:577.73Ref: TM-T4257
1mg40.00€2mg54.00€5mg93.00€10mg133.00€25mg259.00€50mg358.00€100mg500.00€1mL*10mM (DMSO)105.00€KHS101 hydrochloride
CAS:KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.Formula:C18H22ClN5SPurity:99.6%Color and Shape:SolidMolecular weight:375.92Ref: TM-T5170
2mg34.00€5mg52.00€10mg80.00€25mg147.00€50mg239.00€100mg350.00€200mg497.00€1mL*10mM (DMSO)58.00€Pyridone 6
CAS:Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).Formula:C18H16FN3OPurity:97.1% - 98.74%Color and Shape:SolidMolecular weight:309.34Ref: TM-T3080
1mg50.00€2mg71.00€5mg105.00€10mg173.00€25mg358.00€50mg587.00€100mg888.00€200mg1,198.00€1mL*10mM (DMSO)110.00€ML347
CAS:ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for ALK2 is >300-fold than ALK3.Formula:C22H16N4OPurity:99.30% - ≥95%Color and Shape:SolidMolecular weight:352.39PHA-680632
CAS:PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Formula:C28H35N7O2Purity:98.2%Color and Shape:SolidMolecular weight:501.62Tolebrutinib
CAS:Tolebrutinib is an oral, selective BTK inhibitor, effective for MS research, with brain penetration and IC50s of 0.4/0.7 nM in cells.Formula:C26H25N5O3Purity:98.4% - 98.82%Color and Shape:SolidMolecular weight:455.51Ref: TM-T9125
2mg40.00€5mg71.00€10mg105.00€25mg177.00€50mg264.00€100mg434.00€200mg622.00€1mL*10mM (DMSO)80.00€Src Inhibitor 1
CAS:Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.Formula:C22H19N3O3Purity:99.68% - >99.99%Color and Shape:SolidMolecular weight:373.4Ref: TM-T3593
2mg38.00€5mg56.00€10mg94.00€25mg172.00€50mg268.00€100mg429.00€200mg615.00€1mL*10mM (DMSO)To inquireG5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formula:C22H19F2NO3Purity:97.3%Color and Shape:SolidMolecular weight:383.39Ref: TM-T8742
1mg35.00€5mg71.00€10mg96.00€25mg172.00€50mg248.00€100mg348.00€200mg470.00€1mL*10mM (DMSO)78.00€K02288
CAS:K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.Formula:C20H20N2O4Purity:98% - 99.83%Color and Shape:SolidMolecular weight:352.38Alectinib hydrochloride
CAS:Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)Formula:C30H35ClN4O2Purity:99.74% - 99.96%Color and Shape:SolidMolecular weight:519.08Gilteritinib
CAS:Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM,Formula:C29H44N8O3Purity:97.75% - 99.90%Color and Shape:SolidMolecular weight:552.71Ref: TM-T4409
1g1,288.00€1mg38.00€2mg52.00€5mg85.00€10mg114.00€25mg177.00€50mg261.00€100mg411.00€500mg954.00€GNF-2
CAS:GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.Formula:C18H13F3N4O2Purity:98.17% - ≥95%Color and Shape:SolidMolecular weight:374.32PF-04929113 Mesylate
CAS:PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37Formula:C26H34F3N5O7SPurity:99% - 99.46%Color and Shape:SolidMolecular weight:617.63Ref: TM-T4342
1mg73.00€2mg95.00€5mg150.00€10mg273.00€25mg396.00€50mg583.00€100mg832.00€500mg1,684.00€1mL*10mM (DMSO)220.00€Branebrutinib
CAS:Branebrutinib (BMS986195) is a potent, covalent inhibitor of Bruton's tyrosine kinase (BTK), >5,000-fold selective over all kinases outside of the Tec family.Formula:C20H23FN4O2Purity:95.86% - 99.31%Color and Shape:SolidMolecular weight:370.42PT-2385
CAS:PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).Formula:C17H12F3NO4SPurity:98.91% - 99.55%Color and Shape:SolidMolecular weight:383.34Ref: TM-T7848
1mg63.00€2mg93.00€5mg144.00€10mg222.00€25mg379.00€50mg532.00€100mg740.00€200mg982.00€1mL*10mM (DMSO)119.00€FLLL32
CAS:FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).Formula:C28H32O6Purity:97% - 97.90%Color and Shape:SolidMolecular weight:464.55Ref: TM-T6838
2mg43.00€5mg63.00€10mg88.00€25mg117.00€50mg187.00€100mg333.00€500mg797.00€1mL*10mM (DMSO)69.00€Baricitinib
CAS:Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. Cost-effective and quality-assured.Formula:C16H17N7O2SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:371.42Ref: TM-T2485
5mg48.00€10mg70.00€25mg95.00€50mg109.00€100mg137.00€200mg178.00€500mg295.00€1mL*10mM (DMSO)65.00€FM-381
CAS:FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.Formula:C24H24N6O2Purity:98.44%Color and Shape:SolidMolecular weight:428.49Ref: TM-T5091
1mg47.00€2mg62.00€5mg92.00€10mg128.00€25mg212.00€50mg319.00€100mg485.00€1mL*10mM (DMSO)107.00€PF04929113
CAS:PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.Formula:C25H30F3N5O4Purity:99.04%Color and Shape:SolidMolecular weight:521.53Ref: TM-T6341
1mg37.00€2mg50.00€5mg79.00€10mg113.00€25mg177.00€50mg334.00€100mg500.00€1mL*10mM (DMSO)92.00€Roblitinib
CAS:Roblitinib (FGF-401), an FGFR4 inhibitor, potentially blocks tumor growth by halting cell proliferation and survival.Formula:C25H30N8O4Purity:97.27% - 99%Color and Shape:SolidMolecular weight:506.56WDR5-0103
CAS:WDR5-0103 (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).Formula:C21H25N3O4Purity:98% - 99.61%Color and Shape:SolidMolecular weight:383.44GNF-7
CAS:GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.Formula:C28H24F3N7O2Purity:97.05% - 99.7%Color and Shape:SolidMolecular weight:547.53Decernotinib
CAS:Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.Formula:C18H19F3N6OPurity:99.28% - >99.99%Color and Shape:SolidMolecular weight:392.38Ref: TM-T2636
1mg34.00€2mg48.00€5mg71.00€10mg99.00€25mg197.00€50mg295.00€100mg447.00€1mL*10mM (DMSO)79.00€Olverembatinib
CAS:Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).Formula:C29H27F3N6OPurity:98.53% - >99.99%Color and Shape:SolidMolecular weight:532.56Ref: TM-T3071
1mg34.00€2mg43.00€5mg63.00€10mg95.00€25mg190.00€50mg304.00€100mg416.00€1mL*10mM (DMSO)73.00€H3B-6527
CAS:H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic activity.Formula:C29H34Cl2N8O4Purity:97.45%Color and Shape:SolidMolecular weight:629.54Ref: TM-T7738
1mg66.00€5mg160.00€10mg260.00€25mg502.00€50mg710.00€100mg1,009.00€1mL*10mM (DMSO)268.00€GLPG0634 analog
CAS:GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formula:C23H18N6O2Purity:99.52% - >99.99%Color and Shape:SolidMolecular weight:410.43Ref: TM-T3076
1mg38.00€2mg50.00€5mg84.00€10mg137.00€25mg250.00€50mg442.00€100mg623.00€500mg1,305.00€1mL*10mM (DMSO)93.00€KC7F2
CAS:KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.Formula:C16H16Cl4N2O4S4Purity:98% - 99.11%Color and Shape:SolidMolecular weight:570.38WHI-P97
CAS:WHI-P97 is a rationally designed potent inhibitor of JAK-3.Formula:C16H13Br2N3O3Purity:99.93%Color and Shape:SolidMolecular weight:455.1Ruxolitinib (S enantiomer)
CAS:Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.Formula:C17H18N6Purity:99.37% - 99.79%Color and Shape:SolidMolecular weight:306.36SYR127063
CAS:SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.Formula:C23H20ClF3N4O3Purity:98.57%Color and Shape:SolidMolecular weight:492.88Peficitinib
CAS:Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.Formula:C18H22N4O2Purity:98.67% - 99.4%Color and Shape:SolidMolecular weight:326.39Ref: TM-T6933
2mg38.00€5mg63.00€10mg99.00€25mg172.00€50mg268.00€100mg416.00€200mg610.00€1mL*10mM (DMSO)70.00€Oclacitinib
CAS:Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000Formula:C15H23N5O2SPurity:98% - 98.45%Color and Shape:White To Off-White SolidMolecular weight:337.44FGFR4-IN-1
CAS:FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).Formula:C24H27N7O5Purity:98.96%Color and Shape:SolidMolecular weight:493.52SGI-7079
CAS:SGI-7079: selective Axl inhibitor; hinders tumor growth dose-dependently; may target EGFR inhibitor resistance.Formula:C26H26FN7Purity:95.51% - 99.26%Color and Shape:SolidMolecular weight:455.53Ref: TM-T6982
2mg39.00€5mg58.00€10mg92.00€25mg178.00€50mg230.00€100mg334.00€500mg782.00€1mL*10mM (DMSO)64.00€WDR5-0103 hydrochloride[890190-22-4(free base)]
WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd:Formula:C21H26ClN3O4Purity:99.66%Color and Shape:SolidMolecular weight:419.9WHI-P97 HCl
WHI-P97 HCl is a potent and selective JAK-3 inhibitor.Formula:C16H14Br2ClN3O3Purity:99.49%Color and Shape:SolidMolecular weight:491.56Ref: TM-T4657L
2mg34.00€5mg48.00€10mg86.00€25mg138.00€50mg182.00€100mg261.00€200mg371.00€1mL*10mM (DMSO)73.00€JAK3-IN-6
CAS:JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nMFormula:C19H18N4O3Purity:99.94% - 99.94%Color and Shape:SolidMolecular weight:350.37Fursultiamine
CAS:Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.Formula:C17H26N4O3S2Purity:99.63% - 99.90%Color and Shape:SolidMolecular weight:398.54SAR-20347
CAS:SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).Formula:C21H18ClFN4O4Purity:98.99% - 99.77%Color and Shape:SolidMolecular weight:444.84Ref: TM-T4210
1mg34.00€5mg75.00€10mg110.00€25mg215.00€50mg334.00€100mg557.00€200mg775.00€1mL*10mM (DMSO)84.00€JANEX-1
CAS:JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formula:C16H15N3O3Purity:98% - 99.81%Color and Shape:SolidMolecular weight:297.31Fosifidancitinib
CAS:Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.Formula:C21H21FN5O7PPurity:99.54%Color and Shape:SolidMolecular weight:505.39Ref: TM-T38624
1mg93.00€2mg117.00€5mg177.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,099.00€Abrocitinib
CAS:Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).Formula:C14H21N5O2SPurity:99.09% - 99.91%Color and Shape:SolidMolecular weight:323.41NCT-503
CAS:NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.Formula:C20H23F3N4SPurity:98.91% - 99.84%Color and Shape:SolidMolecular weight:408.48Ref: TM-T4213
2mg39.00€5mg59.00€10mg95.00€25mg177.00€50mg321.00€100mg477.00€200mg667.00€1mL*10mM (DMSO)65.00€BX-912
CAS:BX-912 inhibits PDK1 with IC50 of 12 nM; over 10x more selective versus C-Kit, EGFR, PKA, PKC.Formula:C20H23BrN8OPurity:98.29% - 99.34%Color and Shape:SolidMolecular weight:471.35Ref: TM-T1837
1mg50.00€2mg71.00€5mg85.00€10mg137.00€25mg281.00€50mg470.00€100mg632.00€1mL*10mM (DMSO)88.00€Momelotinib
CAS:Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formula:C23H22N6O2Purity:97.07% - 99.56%Color and Shape:SolidMolecular weight:414.46Ref: TM-T1849
1mg35.00€2mg50.00€5mg77.00€10mg89.00€25mg158.00€50mg245.00€100mg385.00€200mg592.00€1mL*10mM (DMSO)84.00€Ensartinib hydrochloride
CAS:Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of knownFormula:C26H29Cl4FN6O3Purity:98.73%Color and Shape:SolidMolecular weight:634.36Ref: TM-T22324
1mg54.00€5mg114.00€10mg177.00€25mg356.00€50mg580.00€100mg888.00€1mL*10mM (DMSO)158.00€CEP-33779
CAS:CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.Formula:C24H26N6O2SPurity:98.24% - ≥95%Color and Shape:SolidMolecular weight:462.57Ref: TM-T6122
1mg43.00€2mg56.00€5mg93.00€10mg137.00€25mg231.00€50mg356.00€100mg530.00€500mg1,153.00€1mL*10mM (DMSO)92.00€Rigosertib
CAS:Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.Formula:C21H25NO8SPurity:99.53%Color and Shape:SolidMolecular weight:451.49UM-164
CAS:UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.Formula:C30H31F3N8O3SPurity:98.72% - 99.52%Color and Shape:SolidMolecular weight:640.68Infigratinib
CAS:Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 andFormula:C26H31Cl2N7O3Purity:98% - 98.97%Color and Shape:SolidMolecular weight:560.48Ref: TM-T1975
5mg44.00€10mg57.00€25mg84.00€50mg90.00€100mg144.00€200mg259.00€500mg437.00€1mL*10mM (DMSO)48.00€WZ8040
CAS:WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).Formula:C24H25ClN6OSPurity:97.42% - 99.785%Color and Shape:SolidMolecular weight:481.01LDN-193189 HCl
CAS:LDN-193189 HCl (LDN193189 Hydrochloride) is a selective BMP type I receptor kinases inhibitor.Formula:C25H22N6·HClPurity:99.49% - 99.53%Color and Shape:SolidMolecular weight:442.94Ref: TM-T6158
1mg34.00€2mg46.00€5mg66.00€10mg88.00€25mg147.00€50mg215.00€100mg358.00€200mg537.00€1mL*10mM (DMSO)81.00€X-376
CAS:X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase ALK with potential antineoplastic activity.Formula:C25H25Cl2FN6O3Purity:97.87%Color and Shape:SolidMolecular weight:547.41Ref: TM-T3550
1mg34.00€2mg48.00€5mg93.00€10mg113.00€25mg244.00€50mg405.00€100mg550.00€1mL*10mM (DMSO)100.00€Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.
Formula:C23H26FN6O9PPurity:93.08% - 99.38%Color and Shape:SolidMolecular weight:580.46Dapagliflozin
CAS:Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.Formula:C21H25ClO6Purity:99.5% - 99.93%Color and Shape:SolidMolecular weight:408.87Ref: TM-T2389
5mg47.00€10mg60.00€25mg77.00€50mg94.00€100mg107.00€200mg142.00€1500mg284.00€1mL*10mM (DMSO)52.00€Treprostinil Sodium
CAS:Treprostinil Sodium (UT-15) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).Formula:C23H33NaO5Purity:99.67% - >99.99%Color and Shape:SolidMolecular weight:412.5Lificiguat
CAS:Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alphaFormula:C19H16N2O2Purity:98.85% - 99.92%Color and Shape:SolidMolecular weight:304.34Ref: TM-T4381
2mg34.00€5mg49.00€10mg64.00€25mg128.00€50mg227.00€100mg393.00€200mg695.00€1mL*10mM (DMSO)50.00€BMS 599626 2HCl
CAS:BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100Formula:C27H29FN8O3Cl2Purity:99.94%Color and Shape:SoildMolecular weight:603.48MGCD-265 analog
CAS:Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Formula:C26H20FN5O2S2Purity:98.06% - 98.68%Color and Shape:SolidMolecular weight:517.6Epidermal Growth Factor
CAS:EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.Formula:C270H401N73O83S7Purity:97.17%Color and Shape:SolidMolecular weight:6222Semaxinib
CAS:Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.
Formula:C15H14N2OPurity:99.84%Color and Shape:Yellow To Yellow OrangeMolecular weight:238.28R1530
CAS:R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.Formula:C18H14ClFN4OPurity:98.422%Color and Shape:SolidMolecular weight:356.78Ref: TM-TQ0317
1mg39.00€2mg52.00€5mg84.00€10mg130.00€25mg264.00€50mg423.00€100mg640.00€1mL*10mM (DMSO)93.00€GN44028
CAS:GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.
Formula:C18H15N3O2Purity:99.52%Color and Shape:SolidMolecular weight:305.33Isoliquiritin apioside
CAS:Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.Formula:C26H30O13Purity:98.84% - 99.27%Color and Shape:SolidMolecular weight:550.51Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).
Formula:C28H24FN3O5Purity:99.68% - 99.88%Color and Shape:SolidMolecular weight:501.51Belzutifan
CAS:"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."Formula:C17H12F3NO4SPurity:99.34% - 99.88%Color and Shape:SolidMolecular weight:383.34Ref: TM-T16679
1mg66.00€5mg144.00€10mg205.00€25mg389.00€50mg625.00€100mg888.00€200mg1,198.00€1mL*10mM (DMSO)158.00€Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formula:C28H25ClFN3O5Purity:99.97%Color and Shape:SolidMolecular weight:537.96Ref: TM-T5164
1mg42.00€2mg52.00€5mg65.00€10mg92.00€25mg160.00€50mg235.00€100mg330.00€200mg538.00€500mg860.00€Dapolsertib
CAS:Dapolsertib (SEL24-B489) is an orally active and efficient PIM and FLT3-ITD inhibitor, reducing PIM-specific substrate phosphorylation.Formula:C15H18Br2N4O2Purity:99.61%Color and Shape:SolidMolecular weight:446.14GS-829845
CAS:GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-lifeFormula:C17H19N5O2SPurity:99.93%Color and Shape:SolidMolecular weight:357.43CCT241161
CAS:CCT241161: oral pan-RAF inhibitor; IC50s: LCK (3 nM), CRAF (6), SRC (10), V600E-BRAF (15), BRAF (30); fights BRAF/NRAS melanomas, anti-proliferative.Formula:C28H27N7O3SPurity:99.76% - 99.77%Color and Shape:SolidMolecular weight:541.62TG 100801
CAS:TG 100801 is a dual inhibitor of VEGFr2 and Src family kinases and is a candidate compound for the treatment of age-related macular degeneration (AMD).Formula:C33H30ClN5O3Purity:99.28% - 99.61%Color and Shape:SolidMolecular weight:580.08Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurity:99.85%Color and Shape:SolidMolecular weight:482Tivozanib hydrochloride hydrate
CAS:Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .Formula:C22H22Cl2N4O6Purity:98.66% - 99.99%Color and Shape:SolidMolecular weight:509.34GSK1904529A
CAS:GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .Formula:C44H47F2N9O5SPurity:98.2% - 99.76%Color and Shape:SolidMolecular weight:851.96Osunprotafib
CAS:Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors.Cost-effective and quality-assured.Formula:C17H24FN3O4SPurity:97.11% - 99.91%Color and Shape:SolidMolecular weight:385.45Itacnosertib
CAS:Itacnosertib (TP-0184) is an orally available ACRV1 (ALK-2), FLT3 and JAK2 inhibitor that inhibits the growth of tumor cells,antitumor and antileukemic.Formula:C26H28N8OPurity:99.38%Color and Shape:SolidMolecular weight:468.55Ref: TM-T39104
1mg92.00€5mg192.00€10mg313.00€25mg595.00€50mg888.00€100mg1,234.00€200mg1,665.00€1mL*10mM (DMSO)212.00€
![WDR5-0103 hydrochloride[890190-22-4(free base)]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT5140.webp&w=3840&q=75)
