Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(166 products)
- Bcr-Abl(118 products)
- EGFR(582 products)
- FAK(72 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- JAK(243 products)
- PDGFR(129 products)
- RAAS(89 products)
- Src(82 products)
- Syk(37 products)
- Thrombin(57 products)
- VDA(2 products)
- VEGFR(242 products)
Show 6 more subcategories
Found 2382 products of "Angiogenesis"
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Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purity:99.54% - 99.77%Color and Shape:SolidMolecular weight:482.51Ref: TM-T7104
5mg49.00€10mg74.00€25mg122.00€50mg202.00€100mg339.00€200mg507.00€500mg800.00€1mL*10mM (DMSO)54.00€Alflutinib mesylate
CAS:Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.Formula:C29H35F3N8O5SPurity:97.94% - 99.63%Color and Shape:SolidMolecular weight:664.70ATH686
CAS:ATH686 is an potent and selective Inhibitor of FLT3.Formula:C25H28F3N7O2Purity:98.07%Color and Shape:SolidMolecular weight:515.53Ref: TM-T7673
1mg106.00€5mg259.00€10mg416.00€25mg707.00€50mg938.00€100mg1,293.00€1mL*10mM (DMSO)283.00€Ceritinib dihydrochloride
CAS:Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase with antitumour effect.Formula:C28H38Cl3N5O3SPurity:99.85% - 99.99%Color and Shape:SolidMolecular weight:631.062,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.Formula:C16H13Cl2N3O2Purity:98.77%Color and Shape:SolidMolecular weight:350.2Tandutinib
CAS:Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formula:C31H42N6O4Purity:99.45% - ≥98%Color and Shape:White SolidMolecular weight:562.7Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formula:C21H21FN6OPurity:99.35% - 99.92%Color and Shape:SolidMolecular weight:392.43Xanthinol Nicotinate
CAS:Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increasedFormula:C13H21N5O4·C6H5NO2Purity:99.91%Color and Shape:White Crystalline PowderMolecular weight:434.45Futibatinib
CAS:Futibatinib (TAS-120) is an orally active, potent,and irreversible FGFR inhibitor of FGFR1, FGFR2, FGFR3, and FGFR4.Cost-effective and quality-assured.Formula:C22H22N6O3Purity:97.66% - 99.44%Color and Shape:SolidMolecular weight:418.45Ref: TM-T5044
1mg50.00€5mg114.00€10mg167.00€25mg313.00€50mg485.00€100mg627.00€200mg890.00€1mL*10mM (DMSO)127.00€(Z)-SU4312
CAS:(Z)-SU4312 is a inhibitor of MAO-B and NOS(IC50 value of 0.2 μM, 19.0μM,respectively).
Formula:C17H16N2OPurity:99.17%Color and Shape:SolidMolecular weight:264.32Desmethylanethol trithione
CAS:Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.
Formula:C9H6OS3Purity:98.05% - 98.41%Color and Shape:SolidMolecular weight:226.34WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formula:C17H14BrN3OPurity:98.92% - 99.73%Color and Shape:SolidMolecular weight:356.22JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purity:99.41% - 99.97%Color and Shape:SolidMolecular weight:466.33Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFormula:C18H22N2OPurity:98.21% - 99.87%Color and Shape:Yellow SolidMolecular weight:282.38Momelotinib HCl
CAS:Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.Formula:C23H24Cl2N6O2Color and Shape:SolidMolecular weight:487.38Gusacitinib HCl
CAS:Gusacitinib (ASN-002/EN-3351), a potent SYK/JAK inhibitor, has strong antitumor activity in various cancers.Formula:C24H29ClN8O2Color and Shape:SolidMolecular weight:497BI-4020
CAS:BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.Formula:C30H38N8O2Purity:97.21% - >99.99%Color and Shape:SolidMolecular weight:542.68Ref: TM-T10534
1mg161.00€5mg376.00€10mg538.00€25mg803.00€50mg1,071.00€100mg1,431.00€200mg1,953.00€1mL*10mM (DMSO)447.00€Alectinib
CAS:Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.Formula:C30H34N4O2Purity:98% - 99.94%Color and Shape:SolidMolecular weight:482.62Ref: TM-T1936
2mg44.00€5mg65.00€10mg82.00€50mg100.00€100mg159.00€200mg245.00€500mg414.00€1mL*10mM (DMSO)70.00€D4476
CAS:D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).Formula:C23H18N4O3Purity:99.7% - 99.96%Color and Shape:SolidMolecular weight:398.41BMS-911543
CAS:BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.Formula:C23H28N8OPurity:97.69% - 99.98%Color and Shape:SolidMolecular weight:432.52Filgotinib
CAS:Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formula:C21H23N5O3SPurity:98.03% - ≥95%Color and Shape:SolidMolecular weight:425.5Blu-782
CAS:Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)
Formula:C31H42N6O4Purity:99.51%Color and Shape:SolidMolecular weight:562.7ZD-4190
CAS:ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.Formula:C19H16BrFN6O2Purity:99.12%Color and Shape:SolidMolecular weight:459.27Ref: TM-T5475
1mg80.00€5mg173.00€10mg261.00€25mg414.00€50mg567.00€100mg767.00€200mg1,018.00€1mL*10mM (DMSO)175.00€ALK kinase inhibitor-1
CAS:SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.Formula:C28H32FN5O3SPurity:99.84%Color and Shape:SolidMolecular weight:537.651-Naphthyl PP1 hydrochloride
CAS:1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-SrcFormula:C19H20ClN5Purity:98.63%Color and Shape:SolidMolecular weight:353.85VH-298
CAS:VH-298 blocks VHL:HIF-α interaction, stabilizes HIF-α, and triggers hypoxic response differently by inhibiting VHL post-HIF-α PHD hydroxylation.
Formula:C27H33N5O4SPurity:99.17% - >99.99%Color and Shape:SolidMolecular weight:523.65CEP-28122 mesylate salt
CEP-28122 mesylate, a diaminopyrimidine, selectively inhibits ALK with IC50 of 1.9 nM and exhibits antitumor effects.Formula:C29H39ClN6O6SColor and Shape:SolidMolecular weight:635.17RK-24466
CAS:RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.Formula:C23H22N4OPurity:98.07%Color and Shape:SolidMolecular weight:370.45Ref: TM-T16760
1mg66.00€5mg144.00€10mg227.00€25mg393.00€50mg588.00€100mg905.00€1mL*10mM (DMSO)159.00€Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormula:C21H17ClF4N4O4Purity:99.69%Color and Shape:SolidMolecular weight:500.83Ref: TM-T1792L
5mg34.00€10mg46.00€25mg65.00€50mg94.00€100mg133.00€200mg197.00€500mg329.00€1mL*10mM (DMSO)55.00€Benidipine hydrochloride
CAS:Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formula:C28H32ClN3O6Purity:99.80%Color and Shape:SolidMolecular weight:542.03LW6
CAS:LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formula:C26H29NO5Purity:98.1% - 98.22%Color and Shape:SolidMolecular weight:435.51Ref: TM-T3494
2mg44.00€5mg65.00€10mg94.00€25mg173.00€50mg281.00€100mg424.00€500mg888.00€1mL*10mM (DMSO)65.00€Neratinib
CAS:Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formula:C30H29ClN6O3Purity:96.17% - 99.85%Color and Shape:SolidMolecular weight:557.04Lenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formula:C22H23ClN4O7SPurity:99.03% - 99.79%Color and Shape:SolidMolecular weight:522.96Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Formula:C23H26FN6O9PPurity:93.08% - 99.38%Color and Shape:SolidMolecular weight:580.46Ref: TM-T6115
1mg40.00€2mg54.00€5mg84.00€10mg112.00€25mg198.00€50mg318.00€100mg520.00€500mg1,134.00€1mL*10mM (DMSO)96.00€SPHINX31
CAS:SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Formula:C27H24F3N5O2Purity:99.3% - 99.87%Color and Shape:SolidMolecular weight:507.51Ref: TM-T5194
1mg40.00€5mg84.00€10mg97.00€25mg180.00€50mg269.00€100mg430.00€500mg998.00€1mL*10mM (DMSO)87.00€RG14620
CAS:RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.Formula:C14H8Cl2N2Purity:99.82% - 99.87%Color and Shape:SolidMolecular weight:275.13Vactosertib
CAS:Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.Formula:C22H18FN7Purity:98.85% - 99.81%Color and Shape:SolidMolecular weight:399.42Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).
Formula:C28H24FN3O5Purity:99.68% - 99.88%Color and Shape:SolidMolecular weight:501.51Ritlecitinib tosylate
CAS:Ritlecitinib (PF-06651600) is a potent, selective JAK3 inhibitor with proven in vivo efficacy, low clearance, and has undergone clinical trials.Formula:C22H27N5O4SColor and Shape:SolidMolecular weight:457.549Regorafenib mesylate
CAS:Regorafenib mesylate is an oral multi-kinase inhibitor targeting VEGFR, PDGFRβ, Kit, RET, Raf-1 with strong anti-tumor and anti-angiogenic effects.Formula:C22H19ClF4N4O6SColor and Shape:SolidMolecular weight:578.92Danusertib
CAS:Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formula:C26H30N6O3Purity:97.88% - 98.79%Color and Shape:White PowderMolecular weight:474.55PD158780
CAS:PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.Formula:C14H12BrN5Purity:98.81%Color and Shape:SolidMolecular weight:330.18Ref: TM-T5410
1mg38.00€5mg80.00€10mg113.00€25mg205.00€50mg358.00€100mg523.00€200mg750.00€1mL*10mM (DMSO)93.00€Takeda-6d
CAS:Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Formula:C27H19ClFN5O3SPurity:98.27%Color and Shape:SolidMolecular weight:547.99Ref: TM-T22436
1mg92.00€2mg128.00€5mg178.00€10mg268.00€25mg439.00€50mg610.00€100mg820.00€200mg1,099.00€1mL*10mM (DMSO)243.00€Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg49.00€5mg84.00€10mg119.00€25mg205.00€50mg310.00€100mg462.00€500mg1,035.00€1mL*10mM (DMSO)90.00€Isoliquiritin apioside
CAS:Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.Formula:C26H30O13Purity:98.84% - 99.27%Color and Shape:SolidMolecular weight:550.51Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purity:97.89% - 98.66%Color and Shape:SolidMolecular weight:491.39KHS 101
CAS:KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
Formula:C18H21N5SPurity:99.63%Color and Shape:SolidMolecular weight:339.46Bisindolylmaleimide I
CAS:Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formula:C25H24N4O2Purity:97.51% - 98.75%Color and Shape:Orange SolidMolecular weight:412.48IDF-11774
CAS:IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Formula:C23H32N2O2Purity:98.05%Color and Shape:SolidMolecular weight:368.51AST5902 mesylate(2412155-74-7 free base)
CAS:AST5902 mesylate is principal metabolite of Alflutinib in vivo. AST5902 mesylate exerts antineoplastic activity.Formula:C28H33F3N8O5SPurity:97.04% - 99.46%Color and Shape:SolidMolecular weight:650.67Ref: TM-T8945L
1mg128.00€5mg253.00€10mg400.00€25mg662.00€50mg888.00€100mg1,243.00€500mg2,502.00€1mL*10mM (DMSO)405.00€
