Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5598 products of "Apoptosis"
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Mcl1-IN-11
CAS:<p>Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.</p>Formula:C38H41N3O5S2Purity:98%Color and Shape:SolidMolecular weight:683.88Anisperimus
CAS:<p>Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.</p>Formula:C18H39N7O3Purity:98.10%Color and Shape:SolidMolecular weight:401.55APPA
CAS:<p>APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of</p>Formula:C14H13NO3Purity:98%Color and Shape:SolidMolecular weight:243.26BMH-7
CAS:<p>BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.</p>Formula:C20H21N5OPurity:99.71%Color and Shape:SolidMolecular weight:347.41NSC 146109 hydrochloride
CAS:<p>NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.</p>Formula:C17H17ClN2SPurity:99.28%Color and Shape:SolidMolecular weight:316.85Dinoprost
CAS:<p>Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.</p>Formula:C20H34O5Purity:97.94% - 98.04%Color and Shape:White To Off-White Crystalline SolidMolecular weight:354.48TNF-α-IN-1
CAS:<p>TNF-α-IN-1 is a TNF-α inhibitor.</p>Formula:C16H14ClN3O5Purity:98.82%Color and Shape:SolidMolecular weight:363.75MI-1061
CAS:<p>MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM).</p>Formula:C30H26Cl2FN3O4Color and Shape:SolidMolecular weight:582.45Propiomazine
CAS:<p>Propiomazine is an orally active antihistamine compound with sedative properties, useful for controlling insomnia in neurological disorders.</p>Formula:C20H24N2OSPurity:98.5%Color and Shape:SolidMolecular weight:340.48(R)-STU104
CAS:<p>(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.</p>Formula:C18H18O4Purity:98.91% - 99.42%Color and Shape:SolidMolecular weight:298.33CCCI-01
CAS:<p>CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.</p>Formula:C11H9N3O4Purity:>99.99%Color and Shape:SolidMolecular weight:247.21Necrostatin-7
CAS:<p>Necrostatin-7 (Necrostatin 7) is a necrotic apoptosis inhibitor with cardioprotective effects that inhibits RANK-NFATc1 signaling.</p>Formula:C16H10FN5OS2Purity:98.71%Color and Shape:SolidMolecular weight:371.41CEP-1612
CAS:<p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>Formula:C35H53N7O7Color and Shape:SolidMolecular weight:683.84Anticancer agent 147
CAS:<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Formula:C32H40BrN3O2Purity:98%Color and Shape:SolidMolecular weight:578.58p53 Activator 3
CAS:<p>Potent p53 activator, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Formula:C30H37F3N4O4SColor and Shape:SolidMolecular weight:606.7BIBU-1361 dihydrochloride
CAS:<p>BIBU-1361 dihydrochloride inhibits EGFR kinase, blocking MAPKK/MAPK activation.</p>Formula:C22H29Cl3FN7Color and Shape:SolidMolecular weight:516.87CAY10503
CAS:<p>CAY10503: proapoptotic, anti-growth agent; arrests cell cycle at G0-G1; IC50 = 7-23 μM; induces HL60 differentiation in 72 hours.</p>Formula:C18H14O3Color and Shape:SolidMolecular weight:278.3n-Octyl caffeate
CAS:<p>n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.</p>Formula:C17H24O4Color and Shape:SolidMolecular weight:292.37CAY10682
CAS:<p>(±)-Nutlin-3 & CAY10682 inhibit p53-Mdm2; CAY also blocks NF-κB, IKKs phosphorylation, and cancer cell growth (IC50s = 2-6 μM).</p>Formula:C30H25BrFN5OColor and Shape:SolidMolecular weight:570.45Tubulin inhibitor 23
CAS:<p>Potent Tubulin inhibitor 23 (IC50: 4.8 μM) induces apoptosis and has dose-dependent antiangiogenic properties, promising for leukemia research.</p>Formula:C26H23NO6SColor and Shape:SolidMolecular weight:477.53PC-046
CAS:<p>PC-046, a tubulin binder, targets DPC4/SMAD4-deficient tumors, inhibits growth in vitro, and is effective in SCID mice with high oral bioavailability (71%).</p>Formula:C22H18N2O3Color and Shape:SolidMolecular weight:358.39ARN5187 trihydrochloride
CAS:<p>ARN5187 trihydrochloride: a REV-ERBβ inhibitor that blocks transcription, autophagy, and induces apoptosis with lysosomal cytotoxicity.</p>Formula:C24H35Cl3FN3OColor and Shape:SolidMolecular weight:506.912LWG-301
<p>LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.</p>Formula:C28H38N8O3SColor and Shape:SolidMolecular weight:566.72GL-V9
CAS:<p>GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.</p>Formula:C24H27NO5Color and Shape:SolidMolecular weight:409.47pan-HER-IN-2
CAS:<p>pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50</p>Formula:C19H15BrClN5OColor and Shape:SolidMolecular weight:444.71Nevanimibe
CAS:<p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>Formula:C27H39N3OPurity:98%Color and Shape:SolidMolecular weight:421.62PARP1-IN-10
CAS:<p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>Formula:C20H23N3O5Color and Shape:SolidMolecular weight:385.41VEGFR-2-IN-23
CAS:<p>VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.</p>Formula:C22H15N5O2Color and Shape:SolidMolecular weight:381.39AMPK activator 11
CAS:<p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>Formula:C25H20N4O2Purity:98%Color and Shape:SolidMolecular weight:408.45CCT373566
CAS:<p>CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.</p>Formula:C26H29ClF2N6O3Color and Shape:SolidMolecular weight:547Apoptotic agent-3
CAS:<p>"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."</p>Formula:C31H21N5OSColor and Shape:SolidMolecular weight:511.6RIPK1-IN-13
CAS:<p>RIPK1-IN-13 inhibits RIPK1 (IC50=1139 nM), potentially blocking necrosis and treating inflammation.</p>Formula:C21H20ClN3O3Color and Shape:SolidMolecular weight:397.85(S)-PERK-IN-5
CAS:<p>(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).</p>Formula:C25H26F2N4O3Color and Shape:SolidMolecular weight:468.5Se-Methylselenocysteine hydrochloride
CAS:<p>Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.</p>Formula:C4H10ClNO2SePurity:98%Color and Shape:SolidMolecular weight:218.54RO2468
CAS:<p>RO2468 is a potent and orally active inhibitor of the p53-MDM2.</p>Formula:C30H30Cl2FN5O4Purity:98%Color and Shape:SolidMolecular weight:614.49TH-Z835
CAS:<p>TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.</p>Formula:C30H38N6OPurity:98%Color and Shape:SolidMolecular weight:498.66ZC0101
CAS:<p>ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.</p>Formula:C17H15N3O2Color and Shape:SolidMolecular weight:293.32ZT55
CAS:<p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>Formula:C17H16N2O3Color and Shape:SolidMolecular weight:296.32BLM-IN-2
<p>BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.</p>Formula:C33H38BrFN4OColor and Shape:SolidMolecular weight:605.58SIRT6 activator 12q
CAS:<p>SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.</p>Formula:C31H22N2O2Color and Shape:SolidMolecular weight:454.52SKLB0565
CAS:<p>SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.</p>Formula:C20H25ClN6OColor and Shape:SolidMolecular weight:400.91Mcl1-IN-3
CAS:<p>Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.</p>Formula:C27H22ClN3O4Purity:98%Color and Shape:SolidMolecular weight:487.93TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Formula:C20H21N5OSColor and Shape:SolidMolecular weight:379.48PQ1 Succinate
CAS:<p>PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.</p>Formula:C25H28F3N3O6Color and Shape:SolidMolecular weight:523.5Anticancer agent 56
CAS:<p>Anticancer agent 56 (4d) has potent action <3μM IC50 on various cancers, causing G2/M arrest and mitochondrial apoptosis via ROS and caspase activation.</p>Formula:C20H18ClN3O3Color and Shape:SolidMolecular weight:383.83(S)-Erypoegin K
CAS:<p>(S)-Erypoegin K is a potent anticancer agent that demonstrates strong anti-proliferative activity against HL-60 cells and induces apoptosis.</p>Formula:C20H18O6Color and Shape:SolidMolecular weight:354.35(Rac)-Indoximod
CAS:<p>(Rac)-Indoximod, a robust IDO inhibitor, and IFN-γ combo reduce α-SMA hCM activity and boost apoptosis, aiding cardiac fibrosis.</p>Formula:C12H14N2O2Color and Shape:SolidMolecular weight:218.25CMC2.24
CAS:<p>CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.</p>Formula:C26H21NO5Color and Shape:SolidMolecular weight:427.45SHP2-IN-8
CAS:<p>SHP2-IN-8: reversible, selective SHP2 inhibitor; IC50=23 nM; induces AKT dephosphorylation and Hela cell apoptosis.</p>Formula:C17H21Cl2N5SColor and Shape:SolidMolecular weight:398.35Flupenthixol
CAS:<p>Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant.</p>Formula:C23H25F3N2OSPurity:98%Color and Shape:SolidMolecular weight:434.522,3-DCPE
CAS:<p>Induces p21, S-phase arrest in cancer cells through ERK pathways. IC50: 0.89 μM (LoVo cells), 12.6 μM (fibroblasts).</p>Formula:C11H15Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:264.15BIM-46174
CAS:<p>BIM-46174 has anticancer activity, inhibits the growth of a large number of human cancer cell lines, and induces caspase-3-dependent cancer cell apoptosis.</p>Formula:C22H30N4OSColor and Shape:SolidMolecular weight:398.57c-Met-IN-9
CAS:<p>c-Met-IN-9 is a 4-phenoxypyridine derivative and a c-Met kinase inhibitor (IC50: 12 nM). c-Met-IN-9 induces apoptosis and shows antitumour effects.</p>Formula:C25H19F2N5O3Color and Shape:SolidMolecular weight:475.45MCL-1/BCL-2-IN-3
CAS:<p>MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.</p>Formula:C27H25BrN2O5SColor and Shape:SolidMolecular weight:569.47MDM2-IN-1
CAS:<p>MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.</p>Formula:C23H21Cl2FN2O3Color and Shape:SolidMolecular weight:463.33HDAC-IN-39
CAS:<p>HDAC-IN-39 inhibits HDAC1-3 (IC50: 1.07-2.27 μM), arrests G2/M phase, hinders microtubule polymerization, and is effective against drug-resistant cancers.</p>Formula:C27H26N4O4SColor and Shape:SolidMolecular weight:502.58Bisindolylmaleimide VIII
CAS:<p>Bisindolylmaleimide VIII (Ro-31-7549) is a selective and highly potent protein kinase C (PKC) inhibitor.</p>Formula:C24H22N4O2Purity:97% - 98.01%Color and Shape:SolidMolecular weight:398.46EC359
CAS:<p>EC359 is a Leukemia Inhibitory Factor Receptor (LIFR) inhibitor with anticancer activity for the study of leukemia and endometrial cancer.</p>Formula:C36H38F2O2Purity:98.11% - 98.11%Color and Shape:SolidMolecular weight:540.68Simmiparib
CAS:<p>Simmiparib (SMOCL-9112) is a PARP1 and PARP2 inhibitor that promotes apoptosis.Simmiparib is used to study Parkinson's disease and melanoma.</p>Formula:C23H18F4N6O2Purity:99.05% - 99.51%Color and Shape:SolidMolecular weight:486.42TNF-α-IN-18
CAS:<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Formula:C16H7ClF2O4Purity:99.77%Color and Shape:SolidMolecular weight:336.67GLUT4-IN-2
CAS:<p>GLUT4-IN-2, selective GLUT4 blocker; IC50: 6.8μM (GLUT4), 11.4μM (GLUT1). Induces apoptosis, G0/G1 arrest, has antitumor effects.</p>Formula:C17H11N3O4S2Purity:99.90%Color and Shape:SolidMolecular weight:385.42CHMFL-ABL/KIT-155
CAS:<p>CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).</p>Formula:C33H38F3N5O3Purity:98%Color and Shape:SolidMolecular weight:609.68NSC10010 hydrochloride
CAS:<p>NSC10010 inhibits gammaherpesvirus B-lymphomas by activating NF-κB and c-Myc pathways.</p>Formula:C31H42Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:573.60MK-886 sodium salt
CAS:<p>MK-886 sodium salt inhibits leukotriene biosynthesis in leukocytes.</p>Formula:C27H33ClNNaO2SColor and Shape:SolidMolecular weight:494.06VU 0364739 hydrochloride
CAS:<p>VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.</p>Formula:C26H28ClFN4O2Purity:99.36%Color and Shape:SolidMolecular weight:482.98IMM-H004
CAS:<p>IMM-H004 is an effective inhibitor of BV2 microglia activation.</p>Formula:C16H20N2O4Purity:98%Color and Shape:SolidMolecular weight:304.34Perillic acid
CAS:<p>Perillic acid, a perillyl alcohol metabolite, induces lung cancer cell arrest, apoptosis, and has anti-HSV-1 and immune-modulating effects.</p>Formula:C10H14O2Color and Shape:SolidMolecular weight:166.22SD-36
CAS:<p>SD-36: Potent, selective PROTAC STAT3 degrader, Kd ~50 nM, effective on mutants, IC50=10 nM, strong anti-tumor effects, enables mouse tumor regression.</p>Formula:C59H62F2N9O12PPurity:98% - >99.99%Color and Shape:SoildMolecular weight:1158.15Declopramide
CAS:<p>Declopramide (OXI-104) is a chemosensitizer with antitumor activity that can be used to study colorectal cancer and inflammatory bowel disease.</p>Formula:C13H20ClN3OPurity:98.53%Color and Shape:SolidMolecular weight:269.77Antitumor agent-57
CAS:<p>Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound.</p>Formula:C20H15NO5Color and Shape:SolidMolecular weight:349.34AP23464
CAS:<p>AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.</p>Formula:C26H30N5O2PColor and Shape:SolidMolecular weight:475.52HDAC1/6-IN-1
CAS:<p>HDAC1/6-IN-1, a dual HDAC1 (89 nM) and HDAC6 (13 nM) inhibitor, blocks cancer cell cycle, triggers apoptosis, and halts metastasis.</p>Formula:C32H45N7O4Color and Shape:SolidMolecular weight:591.74Metallo-β-lactamase-IN-5
CAS:<p>Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs).</p>Formula:C19H16N4O3Color and Shape:SolidMolecular weight:348.36Arylquin 1
CAS:<p>Arylquin 1: a Par-4 secretagogue targeting vimentin; causes non-apoptotic cancer cell death via LMP.</p>Formula:C17H16FN3Color and Shape:SolidMolecular weight:281.33PARP1/BRD4-IN-1
CAS:<p>PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.</p>Formula:C29H26N6O3Color and Shape:SolidMolecular weight:506.56Apogossypolone (ApoG2)
CAS:<p>Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i</p>Formula:C28H26O8Color and Shape:SolidMolecular weight:490.5RIPK1-IN-11
CAS:<p>RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.</p>Formula:C23H24N4O4SColor and Shape:SolidMolecular weight:452.53NBI-42902
CAS:<p>NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.</p>Formula:C27H24F3N3O3Color and Shape:SolidMolecular weight:495.49Justicidin B
CAS:<p>Justicidin B: anticancer, proapoptotic, inhibits bone resorption & platelets, antiviral, fungicidal, antiprotozoal.</p>Formula:C21H16O6Color and Shape:SolidMolecular weight:364.35PI3K-IN-34
CAS:<p>PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.</p>Formula:C23H22N6O3Color and Shape:SolidMolecular weight:430.46hnRNPK-IN-1
CAS:<p>hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.</p>Formula:C23H21N3O5Color and Shape:SolidMolecular weight:419.43Caspase-3/7 activator 2
<p>Caspase-3/7 activator 2 triggers apoptosis with tumor selectivity and anti-proliferative properties.</p>Formula:C32H34N2O7Color and Shape:SolidMolecular weight:558.62Allethrin
CAS:<p>Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.</p>Formula:C19H26O3Purity:99.52%Molecular weight:302.41(Z)-4EGI-1
CAS:<p>(Z)-4EGI-1, a Z-isomer, inhibits eIF4E/eIF4G; binds eIF4E (IC50=43.5 μM, Kd=8.74 μM); anticancer properties.</p>Formula:C18H12Cl2N4O4SColor and Shape:SolidMolecular weight:451.28Antiproliferative agent-19
Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.Formula:C26H23NOColor and Shape:SolidMolecular weight:365.47Anticancer agent 47
CAS:<p>Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.</p>Formula:C19H14N2O4SColor and Shape:SolidMolecular weight:366.39GW-3333
CAS:<p>GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.</p>Formula:C22H36N4O4Purity:98%Color and Shape:SolidMolecular weight:420.55PSB 0474
CAS:<p>P2Y6 receptor agonist</p>Formula:C17H20N2O13P2Purity:98%Color and Shape:SolidMolecular weight:522.29MEK-IN-5
CAS:<p>MEK-IN-5: strong MEK inhibitor and NO donor, reduces pMEK/pERK dose/time-dependently, triggers apoptosis in MDA-MB-231 cells.</p>Formula:C29H27FN4O10S2Color and Shape:SolidMolecular weight:674.67(R)-eIF4A3-IN-2
CAS:<p>(R)-eIF4A3-IN-2, a weaker eIF4A3-IN-2 isomer, inhibits eIF4A3 selectively with 110 nM IC50.</p>Formula:C25H19Br2ClN4O2Color and Shape:SolidMolecular weight:602.71RGB-286147
CAS:<p>RGB-286147 is a potent, selective, ATP-competitive Cdks inhibitor.</p>Formula:C23H22Cl2N4O3Purity:98%Color and Shape:SolidMolecular weight:473.35HLI 373
CAS:<p>HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.</p>Formula:C18H23N5O2Color and Shape:SolidMolecular weight:341.41Caspase-9 Inhibitor III
CAS:<p>Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.</p>Formula:C24H35ClN6O9Color and Shape:SolidMolecular weight:587.02PI3Kδ-IN-10
CAS:<p>PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM).</p>Formula:C19H16ClN9Color and Shape:SolidMolecular weight:405.84Topoisomerase I inhibitor 3
CAS:<p>Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.</p>Formula:C18H14FNO3Color and Shape:SolidMolecular weight:311.31Nec-3a
CAS:<p>Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.</p>Formula:C21H18F4N2O4Color and Shape:SolidMolecular weight:438.37Ceranib-2
CAS:<p>Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.</p>Formula:C25H19NO3Purity:98.49%Color and Shape:SolidMolecular weight:381.42CT-1
CAS:<p>CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.</p>Formula:C29H23F3N4OPurity:99.79%Color and Shape:SolidMolecular weight:500.51RSH-7
CAS:<p>RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducing</p>Formula:C22H25FN8OPurity:98.31%Color and Shape:SolidMolecular weight:436.49Z-LEVD-FMK
CAS:<p>Z-LEVD-FMK is a caspase-4 inhibitor with anti-cancer activity, capable of eliminating LPS-induced GCLC protein degradation.</p>Formula:C31H45FN4O10Color and Shape:SolidMolecular weight:652.71
