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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 5593 products of "Apoptosis"

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  • PD-1/PD-L1-IN-28

    CAS:
    <p>PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity.</p>
    Formula:C24H24N4O2
    Color and Shape:Solid
    Molecular weight:400.47
  • HDACs/mTOR Inhibitor 1

    CAS:
    <p>HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,</p>
    Formula:C28H38N8O5
    Color and Shape:Solid
    Molecular weight:566.65
  • Ro 31-7837

    CAS:
    <p>Ro 31-7837 is an opener of potassium channel.</p>
    Formula:C17H16N2O2
    Color and Shape:Solid
    Molecular weight:280.32
  • EAPB 02303

    CAS:
    <p>EAPB 02303, a microtubule inhibitor, induces mitotic arrest, spindle impairment, apoptosis, and has antitumor effects, enhancing Paclitaxel.</p>
    Formula:C17H14N4O2
    Color and Shape:Solid
    Molecular weight:306.32
  • ARN5187 trihydrochloride

    CAS:
    <p>ARN5187 trihydrochloride: a REV-ERBβ inhibitor that blocks transcription, autophagy, and induces apoptosis with lysosomal cytotoxicity.</p>
    Formula:C24H35Cl3FN3O
    Color and Shape:Solid
    Molecular weight:506.912
  • ACA-28

    CAS:
    <p>ACA-28 is an ERK MAPK signalling modulator that induces apoptosis in melanoma cells by overexpressing ERK.</p>
    Formula:C17H16O6
    Purity:98.73%
    Color and Shape:Solid
    Molecular weight:316.31
  • LWG-301


    <p>LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.</p>
    Formula:C28H38N8O3S
    Color and Shape:Solid
    Molecular weight:566.72
  • SB 706504

    CAS:
    <p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>
    Formula:C24H19F3N8O
    Purity:98.686%
    Color and Shape:Solid
    Molecular weight:492.46
  • A 410099.1

    CAS:
    <p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>
    Formula:C27H41ClN4O3
    Purity:99.30%
    Color and Shape:Solid
    Molecular weight:505.1
  • JS-K

    CAS:
    <p>JS-K is a Nitric oxide donor. It has antiproliferative activity.</p>
    Formula:C13H16N6O8
    Color and Shape:Solid
    Molecular weight:384.3
  • Obatoclax

    CAS:
    <p>Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.</p>
    Formula:C20H19N3O
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:317.38
  • NMK-TD-100

    CAS:
    <p>NMK-TD-100: Microtubule disruptor, anti-proliferative, blocks mitosis, causes apoptosis in HeLa; IC50=17.5µM for tubulin polymerization.</p>
    Formula:C19H17N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:367.42
  • Metaproterenol

    CAS:
    <p>Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM).</p>
    Formula:C11H17NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:211.26
  • KY1022

    CAS:
    <p>KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.</p>
    Formula:C17H19N3OS
    Color and Shape:Solid
    Molecular weight:313.42
  • PS121912

    CAS:
    <p>PS121912 is a potent and selective inhibitor of VDR-coactivator.</p>
    Formula:C24H21F3N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:410.43
  • MBM-17

    CAS:
    <p>MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).</p>
    Formula:C28H28N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:480.56
  • DPQZ

    CAS:
    <p>DPQZ is an anti-tubulin compound acting by inducing cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.</p>
    Formula:C20H17N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:315.37
  • SKLB70326

    CAS:
    <p>SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.</p>
    Formula:C15H13N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:299.35
  • NSC-741909

    CAS:
    <p>NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.</p>
    Formula:C16H14ClNO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:271.74
  • ATB-337

    CAS:
    <p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>
    Formula:C23H15Cl2NO2S3
    Color and Shape:Solid
    Molecular weight:504.47
  • KF24345

    CAS:
    <p>KF24345 is an inhibitor of adenosine uptake.</p>
    Formula:C31H38N6O5
    Color and Shape:Solid
    Molecular weight:574.67
  • HI5

    CAS:
    <p>HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, &amp; triggers apoptosis.</p>
    Formula:C42H43N5O8
    Color and Shape:Solid
    Molecular weight:745.82
  • MpsBAY2a

    CAS:
    <p>carcinoma cell proliferation.</p>
    Formula:C29H28N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:476.57
  • Anticancer agent 32

    CAS:
    <p>Compound 2g, an anticancer agent, disrupts cell cycle and induces apoptosis for cancer research.</p>
    Formula:C24H21F2N5O
    Color and Shape:Solid
    Molecular weight:433.45
  • Nevanimibe

    CAS:
    <p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>
    Formula:C27H39N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.62
  • NU-8165

    CAS:
    <p>NU-8165 is an MDM2-p53 protein-protein interaction inhibitor.</p>
    Formula:C24H22ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:407.89
  • PARP1-IN-10

    CAS:
    <p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>
    Formula:C20H23N3O5
    Color and Shape:Solid
    Molecular weight:385.41
  • SLMP53-2

    CAS:
    <p>SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with</p>
    Formula:C26H22N2O2
    Color and Shape:Solid
    Molecular weight:394.47
  • GW837016X

    CAS:
    <p>GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation.</p>
    Formula:C25H20ClFN4OS
    Color and Shape:Solid
    Molecular weight:478.97
  • MDK-4204

    CAS:
    <p>MDK-4204, an anticancer agent, shows significant anti-cancer activity with IC50 values of 8.8 µM and 9.5 µM in PC-3 and DU-145 cells, respectively.</p>
    Formula:C31H29FN4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:492.59
  • RC-33 HCl

    CAS:
    <p>RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.</p>
    Formula:C21H28ClN
    Purity:98%
    Color and Shape:Solid
    Molecular weight:329.91
  • SMBA2

    CAS:
    <p>SMBA2 is a Bax activator. It acts by specifically targeting the binding pocket at S184.</p>
    Formula:C8H16N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:168.24
  • Epirubicin

    CAS:
    <p>Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.</p>
    Formula:C27H29NO11
    Color and Shape:Solid
    Molecular weight:543.52
  • Perillic acid

    CAS:
    <p>Perillic acid, a perillyl alcohol metabolite, induces lung cancer cell arrest, apoptosis, and has anti-HSV-1 and immune-modulating effects.</p>
    Formula:C10H14O2
    Color and Shape:Solid
    Molecular weight:166.22
  • D44

    CAS:
    <p>D44 is a Plasmodium FKBPs inhibitor.</p>
    Formula:C16H16N4OS
    Color and Shape:Solid
    Molecular weight:312.39
  • Anti-inflammatory agent 47

    CAS:
    <p>Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibiting</p>
    Formula:C25H18N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:394.42
  • PHA-680626

    CAS:
    <p>PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).</p>
    Formula:C23H26N6O2S
    Color and Shape:Solid
    Molecular weight:450.56
  • Zonisamide sodium

    CAS:
    <p>Zonisamide sodium is a 1,2 benzisoxazole derivative. It is the first agent of this chemical class to be developed as an antiepileptic drug.</p>
    Formula:C8H8N2NaO3S
    Purity:98%
    Color and Shape:Off-White Solid
    Molecular weight:235.22
  • LG308

    CAS:
    <p>LG308, a synthetic compound, has anti-tumor properties, inducing apoptosis and mitotic arrest, thereby suppressing prostate cancer growth.</p>
    Formula:C19H17FN2O
    Color and Shape:Solid
    Molecular weight:308.35
  • BTK-IN-24

    CAS:
    <p>BTK-IN-24 is a Bruton's tyrosine kinase (BTK) inhibitor with potential anticancer activity, and it can be used in the study of myeloproliferative disorders.</p>
    Formula:C26H19F4N5O2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:509.46
  • GSK962

    CAS:
    <p>GSK962 is a GSK963 inactive enantiomer. It can be used to confirm the on-target effects.</p>
    Formula:C14H18N2O
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:230.31
  • Ferroptosis inducer-1

    CAS:
    <p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>
    Formula:C25H21ClN2O5
    Color and Shape:Solid
    Molecular weight:464.9
  • MYRA-A

    CAS:
    <p>MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.</p>
    Formula:C19H20N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:340.37
  • EGFR-IN-88

    CAS:
    <p>EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosis</p>
    Formula:C22H18Cl2N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:473.37
  • Pim-1 kinase inhibitor 1

    CAS:
    <p>Pim-1 kinase inhibitor 1, IC50 0.11 μM, combats various cancers by inducing apoptosis.</p>
    Formula:C19H13N3O3
    Color and Shape:Solid
    Molecular weight:331.32
  • NHI-2

    CAS:
    <p>NHI-2 is an LDHA inhibitor (IC50 14.7 µM) that blocks glycolysis, induces apoptosis and cell cycle arrest, and suppresses tumor growth in melanoma models.</p>
    Formula:C17H12F3NO3
    Purity:99.981%
    Color and Shape:Solid
    Molecular weight:335.28
  • MG-262

    CAS:
    <p>MG-262 is a reversible proteasome inhibitor with multiple biological activities [1] [2] [3].</p>
    Formula:C25H42BN3O6
    Color and Shape:Solid
    Molecular weight:491.43
  • M199

    CAS:
    <p>M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs.</p>
    Formula:C17H17N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:279.34
  • CDK8/19-IN-1

    CAS:
    <p>CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).</p>
    Formula:C19H18N4O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.5
  • DC-5163

    CAS:
    <p>DC-5163 inhibits GAPDH (IC50: 176.3 nM, Kd: 3.192 μM), targets cancer cell growth and glycolysis.</p>
    Formula:C18H20ClN3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:361.89
  • E64FC26

    CAS:
    <p>E64FC26 is a PDI family pan-inhibitor with antitumor activity that inhibits PDIA1 and PDIA6 and can be used to study multiple myeloma and pancreatic cancer.</p>
    Formula:C19H23F3O2
    Purity:98.1% - 98.1%
    Color and Shape:Solid
    Molecular weight:340.38
  • AMPK activator 11

    CAS:
    <p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>
    Formula:C25H20N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:408.45
  • DJ001

    CAS:
    <p>DJ001: specific PTPσ inhibitor, non-competitive, IC50=1.43 μM, aids hematopoietic stem cell regeneration.</p>
    Formula:C15H12N2O3
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:268.27
  • YLT205

    CAS:
    <p>YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.</p>
    Formula:C16H12BrClN4O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:471.78
  • (E)-[6]-Dehydroparadol

    CAS:
    <p>(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.</p>
    Formula:C17H24O3
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:276.37
  • MR2938

    CAS:
    <p>MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.</p>
    Formula:C21H24N4O3
    Color and Shape:Solid
    Molecular weight:380.44
  • Irbesartan HCl

    CAS:
    <p>Irbesartan: angiotensin II blocker; treats hypertension by inhibiting receptor binding.</p>
    Formula:C25H29ClN6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:465
  • AD-2646

    CAS:
    <p>AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.</p>
    Formula:C23H40N2O4
    Color and Shape:Solid
    Molecular weight:408.57
  • ABD56

    CAS:
    <p>ABD56 inhibits osteoclast formation and activity in vitro and in vivo.</p>
    Formula:C17H18O3
    Color and Shape:Solid
    Molecular weight:270.32
  • Trehalose 6-behenate

    CAS:
    <p>Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.</p>
    Formula:C34H64O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:664.86
  • EL-102

    CAS:
    <p>EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.</p>
    Formula:C19H16N2O3S2
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:384.47
  • MCL-1/BCL-2-IN-4

    CAS:
    <p>MCL-1/BCL-2-IN-4 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor.</p>
    Formula:C26H23BrN2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:555.44
  • DCP-LA

    CAS:
    <p>DCP-LA (FR236924), linoleic acid derivatives, selective and direct activation of PKCε.</p>
    Formula:C20H36O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:308.5
  • Anti-inflammatory agent 11

    CAS:
    <p>Potent anti-inflammatory compound 16 combats tuberculosis, inhibiting Mtb H37Rv and M299 (MICs: 1.3, 6.9 μM) and reduces NO, TNF-α, IL-1β production.</p>
    Formula:C14H14N4OS
    Color and Shape:Solid
    Molecular weight:286.35
  • Rooperol

    CAS:
    <p>Rooperol: a norlignan with p38α inhibiting, immunomodulatory, antitumor, antibacterial, anticonvulsant, and antioxidant properties.</p>
    Formula:C17H14O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:282.29
  • Pentabromophenol

    CAS:
    <p>Pentabromophenol (NSC-5717) suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors.</p>
    Formula:C6HBr5O
    Purity:99.83%
    Color and Shape:Monoclinic Prisms From Acetic Acid; Needles From Alcohol Physical Description Light Brown Powder Insoluble In Water (Ntp 1992)
    Molecular weight:488.59
  • BTK-IN-9

    CAS:
    <p>BTK-IN-9 reversibly inhibits BTK, disrupts mitochondria, boosts ROS, and triggers apoptosis in Z138 cells, impeding condyloma cell growth.</p>
    Formula:C25H19N7O4
    Color and Shape:Solid
    Molecular weight:481.46
  • T-3256336

    CAS:
    <p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>
    Formula:C31H45F2N5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:605.72
  • Antitumor agent-62

    CAS:
    <p>Antitumor agent-62 releases NO, inhibits cancer cell growth, triggers apoptosis, and halts cell cycle at G2/M.</p>
    Formula:C21H19N3O9S
    Color and Shape:Solid
    Molecular weight:489.46
  • PD-1/PD-L1-IN-14

    CAS:
    <p>PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM).</p>
    Formula:C24H24N4O2
    Color and Shape:Solid
    Molecular weight:400.47
  • Tubulin inhibitor 33

    CAS:
    <p>Tubulin Inhibitor 33 is a dose-dependent inhibitor of tubulin polymerization, exhibiting an IC50 value of 9.05 μM.</p>
    Formula:C24H22N4O3
    Color and Shape:Solid
    Molecular weight:414.46
  • Tubulin/HDAC-IN-1

    CAS:
    <p>Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin &amp; HDAC8, blocking polymerization &amp; targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.</p>
    Formula:C21H18N4O3
    Color and Shape:Solid
    Molecular weight:374.39
  • SB-218078

    CAS:
    <p>SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM).</p>
    Formula:C24H15N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:393.39
  • CYD-2-11

    CAS:
    <p>CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.</p>
    Formula:C22H18N2O3
    Color and Shape:Solid
    Molecular weight:358.39
  • DX2-201

    CAS:
    <p>DX2-201 is a potent and selective inhibitor of oxidative phosphorylation (OXPHOS) complex I (IC50: 312 nM) and exhibits anticancer activity.</p>
    Formula:C18H28N2O6S2
    Color and Shape:Solid
    Molecular weight:432.55
  • TrxR inhibitor D9

    CAS:
    <p>TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).</p>
    Formula:C25H20AuOPS
    Color and Shape:Solid
    Molecular weight:596.43
  • Antitumor agent-19

    CAS:
    <p>Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.</p>
    Formula:C24H21ClF3N5O
    Purity:98.95% - 99.38%
    Color and Shape:Solid
    Molecular weight:487.9
  • QTX125

    CAS:
    <p>QTX125: potent, selective HDAC6 inhibitor with strong antitumor effects.</p>
    Formula:C23H19N3O5
    Color and Shape:Solid
    Molecular weight:417.41
  • Topoisomerase II inhibitor 7

    CAS:
    <p>Topoisomerase II inhibitor 7 halts cell division and induces apoptosis, targeting topoisomerase II alpha with a 3.19 μM IC50.</p>
    Formula:C32H28BrN5O5S
    Color and Shape:Solid
    Molecular weight:674.56
  • ATX inhibitor 13

    CAS:
    <p>ATX inhibitor 13: orally active, IC50 3.4 nM, halts RAW264.7 cells at G2, curbs growth/migration, prompts apoptosis, suppresses tumors.</p>
    Formula:C31H35Cl2N5O3
    Color and Shape:Solid
    Molecular weight:596.55
  • HDAC-IN-36

    CAS:
    <p>HDAC-IN-36: Oral HDAC6 inhibitor, IC50 = 11.68 nM, promotes apoptosis &amp; autophagy, anti-tumor &amp; anti-metastatic, for breast cancer research.</p>
    Formula:C29H39N5O5
    Color and Shape:Solid
    Molecular weight:537.65
  • CN128 hydrochloride

    CAS:
    <p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>
    Formula:C15H18ClNO3
    Color and Shape:Solid
    Molecular weight:295.76
  • EGFR-IN-59

    CAS:
    <p>EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.</p>
    Formula:C27H23N5O4S
    Color and Shape:Solid
    Molecular weight:513.57
  • Aurora kinase-IN-1


    <p>Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.</p>
    Formula:C30H25Br2N3O5
    Color and Shape:Solid
    Molecular weight:667.34
  • PD-1/PD-L1-IN 6

    CAS:
    <p>Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.</p>
    Formula:C25H26N2O3
    Color and Shape:Solid
    Molecular weight:402.49
  • MDM2/XIAP-IN-2

    CAS:
    <p>MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP).</p>
    Formula:C29H32N2O4S
    Color and Shape:Solid
    Molecular weight:504.64
  • IZTZ-1

    CAS:
    <p>IZTZ-1: c-MYC G4 stabilizer, reduces expression, blocks cell cycle, induces apoptosis, inhibits B16 melanoma growth.</p>
    Formula:C32H35N7S
    Color and Shape:Solid
    Molecular weight:549.73
  • (S)-PERK-IN-5

    CAS:
    <p>(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).</p>
    Formula:C25H26F2N4O3
    Color and Shape:Solid
    Molecular weight:468.5
  • QM31

    CAS:
    <p>QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).</p>
    Formula:C39H38Cl4N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:768.56
  • ORY-1001 free base

    CAS:
    <p>ORY-1001: potent KDM1A inhibitor (IC50 &lt;20nM), selective, affects THP-1 cell gene regulation and apoptosis, hinders MV(4;11) cell growth (EC50 &lt;1nM).</p>
    Formula:C15H22N2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:230.35
  • Se-Methylselenocysteine hydrochloride

    CAS:
    <p>Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.</p>
    Formula:C4H10ClNO2Se
    Purity:98%
    Color and Shape:Solid
    Molecular weight:218.54
  • p53 Activator 5

    CAS:
    <p>Potent p53 Activator 5, SC150 &lt;0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>
    Formula:C29H32F6N4O
    Color and Shape:Solid
    Molecular weight:566.58
  • PhiKan 083 hydrochloride

    CAS:
    <p>PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).</p>
    Formula:C16H19ClN2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:274.79
  • CAY10506

    CAS:
    <p>CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.</p>
    Formula:C20H26N2O4S3
    Color and Shape:Solid
    Molecular weight:454.63
  • Tubulin polymerization-IN-24

    CAS:
    <p>HMBA (Tubulin-IN-24) inhibits tubulin assembly, boosts GTP hydrolysis, induces apoptosis, and arrests G2/M phase in MCF-7 cells.</p>
    Formula:C22H16O3
    Color and Shape:Solid
    Molecular weight:328.36
  • Erbstatin

    CAS:
    <p>Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.</p>
    Formula:C9H9NO3
    Color and Shape:Solid
    Molecular weight:179.17
  • Atopaxar

    CAS:
    <p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>
    Formula:C29H38FN3O5
    Purity:97.07% - 98.07%
    Color and Shape:Solid
    Molecular weight:527.63
  • BI-0282

    CAS:
    <p>BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.</p>
    Formula:C30H23Cl2FN4O4
    Color and Shape:Solid
    Molecular weight:593.43
  • BPTQ

    CAS:
    <p>BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.</p>
    Formula:C17H16N4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:308.4
  • PI3K/Akt/mTOR-IN-3

    CAS:
    <p>PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.</p>
    Formula:C34H51NO2
    Color and Shape:Solid
    Molecular weight:505.77