Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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Tubulin/HDAC-IN-1
CAS:<p>Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin & HDAC8, blocking polymerization & targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.</p>Formula:C21H18N4O3Color and Shape:SolidMolecular weight:374.39Dinoprost
CAS:<p>Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.</p>Formula:C20H34O5Purity:97.94% - 98.04%Color and Shape:White To Off-White Crystalline SolidMolecular weight:354.48(S)-PERK-IN-5
CAS:<p>(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).</p>Formula:C25H26F2N4O3Color and Shape:SolidMolecular weight:468.5PTG-0861
CAS:<p>PTG-0861 is a selective HDAC6 inhibitor with an IC50 of 5.92 nm, promising for hematological cancer research.</p>Formula:C15H9F5N2O3Color and Shape:SolidMolecular weight:360.24Ceranib-2
CAS:<p>Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.</p>Formula:C25H19NO3Purity:98.49%Color and Shape:SolidMolecular weight:381.42Se-Methylselenocysteine hydrochloride
CAS:<p>Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.</p>Formula:C4H10ClNO2SePurity:98%Color and Shape:SolidMolecular weight:218.54ATSP-7041
CAS:<p>ATSP-7041 is a novel potent and selective dual inhibitor of mdm2 (ki = 0.9 nm) and mdmx (ki = 7 nm)</p>Formula:C87H125N17O21Color and Shape:SolidMolecular weight:1745.02GEM144
CAS:<p>GEM144: oral POLA1/HDAC11 inhibitor; boosts p53, p21; halts G1/S cycle; triggers cell death.</p>Formula:C28H31NO5Color and Shape:SolidMolecular weight:461.55RETRA
CAS:<p>RETRA is an agent of anticancer that acts by exerting anticancer activity in Ewing's sarcoma cells independent of their TP53 status.</p>Formula:C11H12BrNO3S2Purity:98%Color and Shape:SolidMolecular weight:350.25BMS-37
CAS:<p>BMS-37 is a novel inhibitor of PD-1/PD-L1 immune checkpoint.</p>Formula:C27H32N2O4Color and Shape:SolidMolecular weight:448.55Cadein1
<p>Cadein1, an isoquinolinium derivative, induces G2/M phase delay and caspase-dependent apoptosis in cancer cells lacking functional p53.</p>Formula:C33H48F2INO2Color and Shape:SolidMolecular weight:655.64Bcl-2/Mcl-1-IN-2
CAS:<p>Bcl-2/Mcl-1-IN-2 is a Bcl-2 (Ki: 4.70 μM) and Mcl-1 (Ki: 0.88 μM) inhibitor.Bcl-2/Mcl-1-IN-2 can be used in cancer research.</p>Formula:C26H24ClNO3Color and Shape:SolidMolecular weight:433.93AV123
CAS:<p>AV123, a RIPK1 inhibitor, non-cytotoxic, IC50: 12.12 μM; blocks TNF-α necroptosis (EC50: 1.7 μM) not apoptosis; useful in necrosis-related disease studies.</p>Formula:C11H14N4O2Color and Shape:SolidMolecular weight:234.25Anticancer agent 83
CAS:<p>Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.</p>Formula:C20H19N5OSColor and Shape:SolidMolecular weight:377.46c-Met-IN-14
CAS:<p>c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.</p>Formula:C34H38ClFN4O7SColor and Shape:SolidMolecular weight:701.2LLP-3
CAS:<p>Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.</p>Formula:C32H23ClN2O4Color and Shape:SolidMolecular weight:534.99Antioxidant agent-5
CAS:<p>Antioxidant agent-5 (D-6) curbs oxLDL effects, ROS, NF-κB movement, apoptosis in VECs; boosts Nrf2/HO-1; protects endothelium.</p>Formula:C24H24N6OColor and Shape:SolidMolecular weight:412.49Bisindolylmaleimide VIII
CAS:<p>Bisindolylmaleimide VIII (Ro-31-7549) is a selective and highly potent protein kinase C (PKC) inhibitor.</p>Formula:C24H22N4O2Purity:97% - 98.01%Color and Shape:SolidMolecular weight:398.46Bax activator-1
CAS:<p>Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].</p>Formula:C29H36N4O3Color and Shape:SolidMolecular weight:488.62Cl-amidine
CAS:<p>Cl-amidine, an oral PAD inhibitor (IC50: 0.8-6.2 μM for PAD1/3/4), induces apoptosis in cancer cells.</p>Formula:C14H19ClN4O2Purity:98%Color and Shape:SolidMolecular weight:310.78HLI98C
CAS:<p>HLI98C is a HDM2 ubiquitin ligase inhibitor with anti-tumor activity.</p>Formula:C17H9ClN4O4Color and Shape:SolidMolecular weight:368.73PK9327
CAS:<p>PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations.</p>Formula:C21H22N2SColor and Shape:SolidMolecular weight:334.48NVS-CECR2-1
CAS:<p>NVS-CECR2-1 is a CECR2 inhibitor with anti-tumor activity that inhibits chromatin binding of the CECR2 BRD.</p>Formula:C27H37N5O2SPurity:98.68%Color and Shape:SolidMolecular weight:495.68Glucocorticoid receptor modulator 1
CAS:<p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>Formula:C24H23ClN2O4SPurity:99.79%Color and Shape:SolidMolecular weight:470.97IDO1/TDO-IN-1
CAS:<p>IDO1/TDO-IN-1 (30) inhibits IDO1 (Ki=0.23μM) & TDO (Ki=0.73μM); induces apoptosis via Bcl-2/Bax.</p>Formula:C21H16O6Color and Shape:SolidMolecular weight:364.35DBIBB
CAS:<p>DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.</p>Formula:C23H20N2O6SPurity:98.49% - 99.1%Color and Shape:SolidMolecular weight:452.48TRK-IN-23
CAS:<p>TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,</p>Formula:C20H17FN4O2Purity:98%Color and Shape:SolidMolecular weight:364.37S-Gem
CAS:<p>S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.</p>Formula:C13H15F2N3O6S2Purity:98%Color and Shape:SolidMolecular weight:411.4Antiproliferative agent-7
CAS:<p>Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.</p>Formula:C28H32N4OColor and Shape:SolidMolecular weight:440.58MI-389
CAS:<p>MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.</p>Formula:C35H35FN6O6Purity:98.12%Color and Shape:SolidMolecular weight:654.69IM-93
CAS:<p>IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].</p>Formula:C21H28N4O2Color and Shape:SolidMolecular weight:368.47Anti-inflammatory agent 22
CAS:<p>Compound 14a is an oral anti-inflammatory with an IC50 of 14.6 μM for TNF-α, preventing adipogenesis and reducing mouse limb lymphedema.</p>Formula:C22H16O6Color and Shape:SolidMolecular weight:376.36VO-OHPic
CAS:<p>VO-OHPic, a selective PTEN inhibitor (IC50 = 46 nM), reduces apoptosis and inflammation in doxorubicin-induced cardiomyopathy.</p>Formula:C12H10N2O8VColor and Shape:SolidMolecular weight:361.16APPA
CAS:<p>APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of</p>Formula:C14H13NO3Purity:98%Color and Shape:SolidMolecular weight:243.26BMH-7
CAS:<p>BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.</p>Formula:C20H21N5OPurity:99.71%Color and Shape:SolidMolecular weight:347.41PI3Kδ-IN-11
CAS:<p>PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.</p>Formula:C27H21N5OColor and Shape:SolidMolecular weight:431.49CK2/ERK8-IN-1
CAS:<p>TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.</p>Formula:C11H9Br4N3O2Purity:98.22%Color and Shape:SolidMolecular weight:534.82(R)-STU104
CAS:<p>(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.</p>Formula:C18H18O4Purity:98.91% - 99.42%Color and Shape:SolidMolecular weight:298.33SMBA1
CAS:<p>SMBA1 is a Bax agonist with antitumor activity that can induce cell cycle arrest and apoptosis in malignant glioma cells.</p>Formula:C20H13NO3Purity:99.2%Color and Shape:SolidMolecular weight:315.32GKK1032B
CAS:<p>GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.</p>Formula:C32H39NO4Color and Shape:SolidMolecular weight:501.66PI3K-IN-33
CAS:<p>PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.</p>Formula:C23H21BrN6O2Color and Shape:SolidMolecular weight:493.36CZS-241
<p>CZS-241: Oral PLK4 inhibitor (IC50=2.6 nM), less potent TRKA blocker (IC50=2.74 μM), triggers apoptosis and S/G2 arrest, anti-leukemia, safe for normal cells.</p>Formula:C26H24ClF2N9OColor and Shape:SolidMolecular weight:551.98DAT-230
CAS:<p>DAT-230 is a microtubule inhibitor effective against cancer cells, causing cell cycle arrest and apoptosis via caspase activation.</p>Formula:C20H21NO2SColor and Shape:SolidMolecular weight:339.45EC359
CAS:<p>EC359 is a Leukemia Inhibitory Factor Receptor (LIFR) inhibitor with anticancer activity for the study of leukemia and endometrial cancer.</p>Formula:C36H38F2O2Purity:98.11% - 98.11%Color and Shape:SolidMolecular weight:540.68Simmiparib
CAS:<p>Simmiparib (SMOCL-9112) is a PARP1 and PARP2 inhibitor that promotes apoptosis.Simmiparib is used to study Parkinson's disease and melanoma.</p>Formula:C23H18F4N6O2Purity:99.05% - 99.51%Color and Shape:SolidMolecular weight:486.42Anti-melanoma agent 1
CAS:<p>Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.</p>Formula:C28H28N2O2Color and Shape:SolidMolecular weight:424.53UCD38B HCl
CAS:<p>UCD38B HCl, a cell-permeable uPA inhibitor, induces programmed necrosis in high-grade glioma cells.</p>Formula:C15H17Cl2N7O3Purity:98%Color and Shape:SolidMolecular weight:414.25SB 706504
CAS:<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Formula:C24H19F3N8OPurity:98.686%Color and Shape:SolidMolecular weight:492.462,3-DCPE
CAS:<p>Induces p21, S-phase arrest in cancer cells through ERK pathways. IC50: 0.89 μM (LoVo cells), 12.6 μM (fibroblasts).</p>Formula:C11H15Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:264.15TL02-59 dihydrochloride
CAS:<p>TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).</p>Formula:C32H36Cl2F3N5O4Purity:98%Color and Shape:SolidMolecular weight:682.56B-Raf IN 9
CAS:<p>B-Raf IN 9 is a potent B-Raf inhibitor (IC50=24.79 nM), induces G2/M arrest and apoptosis, and inhibits PC-3 prostate cancer cells (IC50=7.83 μM).</p>Formula:C23H20N4OSColor and Shape:SolidMolecular weight:400.5PI3Kα-IN-7
CAS:<p>PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ.</p>Formula:C17H22N8O2SColor and Shape:SolidMolecular weight:402.47MDM2-IN-1
CAS:<p>MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.</p>Formula:C23H21Cl2FN2O3Color and Shape:SolidMolecular weight:463.33HDAC1/6-IN-1
CAS:<p>HDAC1/6-IN-1, a dual HDAC1 (89 nM) and HDAC6 (13 nM) inhibitor, blocks cancer cell cycle, triggers apoptosis, and halts metastasis.</p>Formula:C32H45N7O4Color and Shape:SolidMolecular weight:591.74ASK1-IN-3
CAS:<p>ASK1-IN-3, selective ASK1 inhibitor with 33.8 nM IC50; inhibits cell cycle kinases; induces apoptosis in HepG2 cells.</p>Formula:C18H18N8O2Color and Shape:SolidMolecular weight:378.39Metallo-β-lactamase-IN-5
CAS:<p>Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs).</p>Formula:C19H16N4O3Color and Shape:SolidMolecular weight:348.36VU 0364739 hydrochloride
CAS:<p>VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.</p>Formula:C26H28ClFN4O2Purity:99.36%Color and Shape:SolidMolecular weight:482.98BMH-9
CAS:<p>BMH-9 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Formula:C19H27N3O2Color and Shape:SolidMolecular weight:329.44L 741742 (free base)
CAS:<p>L 741742 is an effective and highly selective antagonist of the D4 dopamine receptor (Ki: 1700, 770, and 3.5 nM at cloned human D2, D3, and D4 receptors).</p>Formula:C23H25ClN2OPurity:98%Color and Shape:SolidMolecular weight:380.91ALC67
CAS:<p>ALC67, a novel 3-propionyl thiazolidine-4-carboxylic acid ethyl ester, activates caspase-9, showing potent anticancer properties.</p>Formula:C15H15NO3SPurity:98%Color and Shape:SolidMolecular weight:289.35NU-8165
CAS:<p>NU-8165 is an MDM2-p53 protein-protein interaction inhibitor.</p>Formula:C24H22ClNO3Purity:98%Color and Shape:SolidMolecular weight:407.89RC-33 HCl
CAS:<p>RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.</p>Formula:C21H28ClNPurity:98%Color and Shape:SolidMolecular weight:329.91SMBA2
CAS:<p>SMBA2 is a Bax activator. It acts by specifically targeting the binding pocket at S184.</p>Formula:C8H16N4Purity:98%Color and Shape:SolidMolecular weight:168.24Tryptophanamide
CAS:<p>Tryptophanamide is a chymotrypsin inhibitor.</p>Formula:C11H13N3OPurity:98%Color and Shape:SolidMolecular weight:203.24NHI-2
CAS:<p>NHI-2 is an LDHA inhibitor (IC50 14.7 µM) that blocks glycolysis, induces apoptosis and cell cycle arrest, and suppresses tumor growth in melanoma models.</p>Formula:C17H12F3NO3Purity:99.981%Color and Shape:SolidMolecular weight:335.28BMS-242
CAS:<p>BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction.</p>Formula:C28H35NO4Purity:98%Color and Shape:SolidMolecular weight:449.58Ethacridine
CAS:<p>Ethacridine acts as an inhibitor of poly (ADP-ribose) glycohydrolase (PARG) and functions as an activator of transcriptional coactivators. It induces apoptosis in thyroid cancer cells and promotes the differentiation of thyroid follicular cells.</p>Formula:C15H15N3OColor and Shape:SolidMolecular weight:253.30GY1-22
CAS:<p>GY1-22, an inhibitor targeting the DNAJA1-mutP53 R175H interaction pocket, holds potential for cancer research applications.</p>Formula:C23H20N4OSColor and Shape:SolidMolecular weight:400.53-(3-Phenoxybenzyl)amino-β-carboline
CAS:<p>3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers.</p>Formula:C24H19N3OColor and Shape:SolidMolecular weight:365.43Antitumor agent-19
CAS:<p>Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.</p>Formula:C24H21ClF3N5OPurity:98.95% - 99.38%Color and Shape:SolidMolecular weight:487.9VEGFR-2-IN-22
CAS:<p>VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.</p>Formula:C26H24ClFN4O6Color and Shape:SolidMolecular weight:542.94A-802715
CAS:<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Formula:C16H26N4O3Purity:96.29%Color and Shape:SolidMolecular weight:322.4p53 Activator 3
CAS:<p>Potent p53 activator, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Formula:C30H37F3N4O4SColor and Shape:SolidMolecular weight:606.7BIBU-1361 dihydrochloride
CAS:<p>BIBU-1361 dihydrochloride inhibits EGFR kinase, blocking MAPKK/MAPK activation.</p>Formula:C22H29Cl3FN7Color and Shape:SolidMolecular weight:516.87Undecylprodigiosin
CAS:<p>Undecylprodigiosin is a classical cytotoxic immunosuppressant, suppressing immune functions. It also inhibits DNA synthesis.</p>Formula:C25H35N3OColor and Shape:SolidMolecular weight:393.56PD-1/PD-L1-IN-20
CAS:<p>PD-1/PD-L1-IN-20 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interaction.</p>Formula:C30H26BrClN2O3Color and Shape:SolidMolecular weight:577.9ARN5187 trihydrochloride
CAS:<p>ARN5187 trihydrochloride: a REV-ERBβ inhibitor that blocks transcription, autophagy, and induces apoptosis with lysosomal cytotoxicity.</p>Formula:C24H35Cl3FN3OColor and Shape:SolidMolecular weight:506.912MM-102
CAS:<p>MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.</p>Formula:C35H49F2N7O4Purity:98.77% - 99.99%Color and Shape:SolidMolecular weight:669.8LWG-301
<p>LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.</p>Formula:C28H38N8O3SColor and Shape:SolidMolecular weight:566.72GL-V9
CAS:<p>GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.</p>Formula:C24H27NO5Color and Shape:SolidMolecular weight:409.47pan-HER-IN-2
CAS:<p>pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50</p>Formula:C19H15BrClN5OColor and Shape:SolidMolecular weight:444.71Verticillin A
CAS:<p>Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.</p>Formula:C30H28N6O6S4Purity:98%Color and Shape:SolidMolecular weight:696.84Nevanimibe
CAS:<p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>Formula:C27H39N3OPurity:98%Color and Shape:SolidMolecular weight:421.62PARP1-IN-10
CAS:<p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>Formula:C20H23N3O5Color and Shape:SolidMolecular weight:385.41Ormeloxifene
CAS:<p>estrogen receptor modulator</p>Formula:C30H35NO3Purity:98%Color and Shape:SolidMolecular weight:457.6Fenoldopam hydrochloride
CAS:<p>Fenoldopam HCl: D1 dopamine receptor agonist, vasodilator, doesn't cross blood-brain barrier, α2-adrenoceptor antagonist.</p>Formula:C16H17Cl2NO3Color and Shape:SolidMolecular weight:342.22NF-κB-IN-5
CAS:<p>NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.</p>Formula:C23H27N3O4Color and Shape:SolidMolecular weight:409.48Tubulin polymerization-IN-22
CAS:<p>Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.</p>Formula:C19H16O4Color and Shape:SolidMolecular weight:308.33CFM-5
CAS:<p>CFM-5 has anticonvulsant activity and is used in epilepsy research.</p>Formula:C23H18BrN3OSPurity:98%Color and Shape:SolidMolecular weight:464.38MPT0B214
CAS:<p>MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.</p>Formula:C20H20N2O5Color and Shape:SolidMolecular weight:368.38PD-1/PD-L1-IN-29
CAS:<p>PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.</p>Formula:C26H24N2O6Color and Shape:SolidMolecular weight:460.48CYD-2-11
CAS:<p>CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.</p>Formula:C22H18N2O3Color and Shape:SolidMolecular weight:358.39BMS-566394
CAS:<p>BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).</p>Formula:C22H21F3N4O4Color and Shape:SolidMolecular weight:462.42SK-7041
CAS:<p>SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.</p>Formula:C19H21N3O3Purity:98%Color and Shape:SolidMolecular weight:339.39Antitumor agent-53
CAS:<p>Antitumor agent-53 hinders tumor growth, induces G2/M cell cycle arrest, and triggers apoptosis via PI3K/AKT in HGC-27 cells.</p>Formula:C24H18FN3OColor and Shape:SolidMolecular weight:383.42p53 Activator 2
CAS:<p>p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.</p>Formula:C20H21N5O2Color and Shape:SolidMolecular weight:363.41CUDC-427
CAS:<p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>Formula:C29H36N6O4SPurity:99.92%Color and Shape:SolidMolecular weight:564.7Trk-IN-9
CAS:<p>Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.</p>Formula:C23H24ClFN6OPurity:98.15%Color and Shape:SolidMolecular weight:454.93EM-12
CAS:<p>EM-12, a Thalidomide analogue, is more active, stable, and boosts rat colon cancer studies.</p>Formula:C13H12N2O3Purity:99.34%Color and Shape:SolidMolecular weight:244.25DK419
CAS:<p>DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.</p>Formula:C16H8ClF6N3OPurity:99.63%Color and Shape:SolidMolecular weight:407.7Ro 08-2750
CAS:<p>Ro 08-2750: A non-peptide NGF inhibitor binding NGF (~1 µM IC50) & selectively inhibits p75NTR over TRKA and MSI RNA-binding (2.7 µM IC50).</p>Formula:C13H10N4O3Purity:98.795%Color and Shape:SolidMolecular weight:270.24Imipramine
CAS:<p>Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.</p>Formula:C19H24N2Purity:99.4%Color and Shape:White To Off-White /Hydrochloride/ SolidMolecular weight:280.41Anticancer agent 110
CAS:<p>Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells</p>Formula:C18H13FN6OSPurity:98%Color and Shape:SolidMolecular weight:380.4Vamotinib
CAS:<p>Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.</p>Formula:C29H27F3N6OPurity:99.64%Color and Shape:SolidMolecular weight:532.56eIF4A3-IN-1
CAS:<p>eIF4A3-IN-1 is an inhibitor of eukaryotic initiation factor 4A3 (eIF4A3). eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.</p>Formula:C29H23BrClN5O2Purity:99.49% - 99.89%Color and Shape:SolidMolecular weight:588.88Etomoxir
CAS:<p>Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM), inhibits fatty acid oxidation. High-Quality, Low-Cost!</p>Formula:C17H23ClO4Purity:98% - 99.39%Color and Shape:SolidMolecular weight:326.82LDCA
CAS:<p>LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.</p>Formula:C8H5Cl3FNOPurity:98.99%Color and Shape:SolidMolecular weight:256.49Alethine
CAS:<p>Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.</p>Formula:C10H22N4O2S2Purity:98.83%Color and Shape:SolidMolecular weight:294.44RIPK3-IN-1
CAS:<p>RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.</p>Formula:C29H25FN4O4Purity:98.27%Color and Shape:SolidMolecular weight:512.53Brigimadlin
CAS:<p>Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.</p>Formula:C31H25Cl2FN4O3Purity:98.17%Color and Shape:SolidMolecular weight:591.46TL4-12
CAS:<p>TL4-12 is a MAP4K2 (GCK) inhibitor that inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation in vitro.</p>Formula:C25H27F3N6O2Purity:98.38%Color and Shape:SolidMolecular weight:500.52JY-2
CAS:<p>JY-2 is a forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity that inhibits FoxO1 transcription and can be used to study psoriasis.</p>Formula:C13H7Cl2N3OPurity:99.66%Color and Shape:SolidMolecular weight:292.12R306465
CAS:<p>R306465 (JNJ-16241199) is an HDAC 1 inhibitor with broad-spectrum anti-tumor activity, inducing apoptosis, and can be used to study solid tumors.</p>Formula:C19H19N5O4SPurity:98.46% - 99.54%Color and Shape:SolidMolecular weight:413.45BCP-T.A
CAS:<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Formula:C23H19Cl2N3OSPurity:99.49%Color and Shape:SolidMolecular weight:456.39NSC49652
CAS:<p>NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.</p>Formula:C14H11NO2Purity:98.98%Color and Shape:SolidMolecular weight:225.24LCS3
CAS:<p>LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3</p>Formula:C11H7ClN2O4Purity:99.68%Color and Shape:SolidMolecular weight:266.64CP 461
CAS:<p>CP 461 is a PDE2A inhibitor that promotes apoptosis in cancer cells without affecting normal cells or COX-1/2.</p>Formula:C25H22ClFN2OPurity:99.82%Color and Shape:SolidMolecular weight:420.91A 419259 trihydrochloride
CAS:<p>A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).</p>Formula:C29H37Cl3N6OPurity:99.75% - 99.96%Color and Shape:SolidMolecular weight:592AZA1
CAS:<p>AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42.</p>Formula:C22H20N6Purity:99.75%Color and Shape:SolidMolecular weight:368.43iCRT-5
CAS:<p>iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity and can be used in the study of multiple myeloma.</p>Formula:C16H17NO5S2Purity:99.68%Color and Shape:SolidMolecular weight:367.44AMG PERK 44
CAS:<p>AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.</p>Formula:C34H29ClN4O2Purity:98.8% - 99.81%Color and Shape:SolidMolecular weight:561.07UC-112
CAS:<p>UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).</p>Formula:C22H24N2O2Purity:99.54%Color and Shape:SolidMolecular weight:348.44NM-3
CAS:<p>NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.</p>Formula:C13H12O6Purity:99.89%Color and Shape:SolidMolecular weight:264.23CMLD-2
CAS:<p>CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.</p>Formula:C31H31NO6Purity:99.99%Color and Shape:SolidMolecular weight:513.58TAI-1
CAS:<p>TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.</p>Formula:C24H21N3O3SPurity:99.58%Color and Shape:SolidMolecular weight:431.51D609
CAS:<p>D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.</p>Formula:C11H15KOS2Purity:97.67% - 99.56%Color and Shape:Off-White PowderMolecular weight:266.46Mepazine
CAS:<p>Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.</p>Formula:C19H22N2SPurity:99.88% - 99.92%Color and Shape:SolidMolecular weight:310.46UK-101
CAS:<p>UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM</p>Formula:C25H48N2O5SiPurity:99.08% - 99.25%Color and Shape:SolidMolecular weight:484.74T025
CAS:<p>T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.</p>Formula:C21H18N8Purity:98.08%Color and Shape:SolidMolecular weight:382.42F16
CAS:<p>F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.</p>Formula:C16H15IN2Purity:99.89%Color and Shape:SolidMolecular weight:362.21Cot inhibitor-1
CAS:<p>Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.</p>Formula:C27H27Cl2FN8Purity:98.59%Color and Shape:SolidMolecular weight:553.46CTA 056
CAS:<p>CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.</p>Formula:C35H34N6OPurity:97.22% - 97.76%Color and Shape:SolidMolecular weight:554.68RET-IN-23
CAS:<p>RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.</p>Formula:C28H28FN11Purity:97.46%Color and Shape:SolidMolecular weight:537.59GSK854
CAS:<p>GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.</p>Formula:C18H19ClN6O4S2Purity:98.79%Color and Shape:SolidMolecular weight:482.96UNC0321
CAS:<p>UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.</p>Formula:C27H45N7O3Purity:99.80%Color and Shape:SolidMolecular weight:515.69Prinomastat
CAS:<p>Prinomastat: orally active, crosses blood-brain barrier, inhibits MMP-1/2/3/9, Ki/IC50s: 0.05-0.3/5.0-79 nM, antitumor.</p>Formula:C18H21N3O5S2Purity:99.23%Color and Shape:SolidMolecular weight:423.51NLRP3/AIM2-IN-3
CAS:<p>NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.</p>Formula:C16H14N2O2Purity:97.04%Color and Shape:SolidMolecular weight:266.29KR-33493
CAS:<p>KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.</p>Formula:C20H18BrN3O3SPurity:99.96%Color and Shape:SolidMolecular weight:460.34HS-276
CAS:<p>HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.</p>Formula:C24H29N5O2Purity:97.852% - 98.81%Color and Shape:SolidMolecular weight:419.52Triciribine phosphate
CAS:<p>Triciribine phosphate (VD 002) is an AKT inhibitor that inhibits neovascularization and can be used in the study of leukemia.</p>Formula:C13H17N6O7PPurity:97.94%Color and Shape:SolidMolecular weight:400.28Ro24-7429
CAS:<p>Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.</p>Formula:C14H13ClN4Purity:99.29% - 99.85%Color and Shape:SolidMolecular weight:272.73Lanperisone HCl
CAS:<p>Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.</p>Formula:C15H19ClF3NOPurity:98.67% - >99.99%Color and Shape:SolidMolecular weight:321.77STAT3-IN-13
CAS:<p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>Formula:C21H20N6O3SPurity:98.89%Color and Shape:SolidMolecular weight:436.49DB1976
CAS:<p>DB1976: Selenophene DB270 analog, inhibits PU.1 (IC50=10 nM), disrupts PU.1/DNA (KD=12 nM), induces apoptosis, cell-permeable.</p>Formula:C20H16N8SePurity:98.74%Color and Shape:SolidMolecular weight:447.35Antifolate C2
CAS:<p>Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.</p>Formula:C19H21N5O6SPurity:99.57%Color and Shape:SolidMolecular weight:447.46RO-5963
CAS:<p>RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).</p>Formula:C24H21ClF2N4O5Purity:99.28%Color and Shape:SolidMolecular weight:518.9P505-15 Acetate
CAS:<p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>Formula:C21H27N9O3Purity:99.99%Color and Shape:SolidMolecular weight:453.5Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Formula:C36H35ClN4O4Purity:99.63%Color and Shape:SolidMolecular weight:623.14Atrosab
CAS:<p>Atrosab is a humanized IgG1 antibody targeting TNFR1, inhibiting TNF-mediated apoptosis, and can be used to study inflammatory and neurodegenerative diseases.</p>Purity:SDS-PAGE:>95%;SEC-HPLC:95.22%Color and Shape:LiquidMolecular weight:146.12 kDaZDLD20
CAS:<p>ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.</p>Formula:C22H22N6OPurity:98.59%Color and Shape:SolidMolecular weight:386.45BC 11 hydrobromide
CAS:<p>The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.</p>Formula:C8H12BBrN2O2SPurity:98.07%Color and Shape:SolidMolecular weight:290.97UCB-5307
CAS:<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Formula:C22H21N3OPurity:98.76%Color and Shape:SolidMolecular weight:343.42HS38
CAS:<p>HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.</p>Formula:C14H12ClN5O2SPurity:98.19%Color and Shape:SolidMolecular weight:349.8Necrostatin-5
CAS:<p>Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.</p>Formula:C19H17N3O2S2Purity:98.03%Color and Shape:SolidMolecular weight:383.49DCG066
CAS:<p>DCG066 is an inhibitor of lysine methyltransferase G9a with anticancer activity and may be used in the study of leukemia.</p>Formula:C30H31F6N3O2Purity:98.26% - 98.38%Color and Shape:SolidMolecular weight:579.58SLMP53-1
CAS:<p>SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migration</p>Formula:C20H18N2O2Purity:99.64%Color and Shape:SolidMolecular weight:318.37SCFSkp2-IN-2
CAS:<p>SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.</p>Formula:C17H20N4O2Purity:99.86%Color and Shape:SolidMolecular weight:312.37AOH1160
CAS:<p>AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).</p>Formula:C25H20N2O3Purity:98.46% - 99.52%Color and Shape:SolidMolecular weight:396.44HTH-01-091
CAS:<p>HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,</p>Formula:C26H28Cl2N4O2Purity:98.4%Color and Shape:SolidMolecular weight:499.43SB 699551 dihydrochloride
CAS:<p>SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.</p>Formula:C34H47Cl2N3OPurity:99.83%Color and Shape:SolidMolecular weight:584.66C6 Ceramide
CAS:<p>C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.</p>Formula:C24H47NO3Purity:99.67%Color and Shape:SolidMolecular weight:397.63TC-DAPK 6
CAS:<p>TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.</p>Formula:C17H12N2O2Purity:98.73%Color and Shape:SolidMolecular weight:276.29Deferitazole
CAS:<p>Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.</p>Formula:C18H25NO7SPurity:99.48%Color and Shape:SolidMolecular weight:399.46Exisulind
CAS:<p>Exisulind (CP248) triggers apoptosis via PKG activation, shows antitumor effects, and inhibits growth in various rodent cancer models.</p>Formula:C20H17FO4SPurity:97.94%Color and Shape:SolidMolecular weight:372.41HBED
CAS:<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Formula:C20H24N2O6Purity:97.35% - 98.58%Color and Shape:SolidMolecular weight:388.41MMRi64
CAS:<p>MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.</p>Formula:C22H17Cl2N3OPurity:99.93%Color and Shape:SolidMolecular weight:410.3Minodronic acid
CAS:<p>Minodronic acid (YM-529) is a P2X2/3 antagonist with anticancer properties, inhibiting cell growth and metastasis, and used in osteoporosis research.</p>Formula:C9H12N2O7P2Purity:98.02%Color and Shape:SolidMolecular weight:322.15FA16
<p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>Formula:C22H27F3N4O2SPurity:99.44%Color and Shape:SolidMolecular weight:468.54CBS9106
CAS:<p>CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.</p>Formula:C18H21ClF3N3O3Purity:98.98%Color and Shape:SolidMolecular weight:419.83TNIK-IN-3
CAS:<p>TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).</p>Formula:C23H18FN3O2Purity:98.39%Color and Shape:SolidMolecular weight:387.41Tubulin inhibitor 32
CAS:<p>Tubulin inhibitor 32 is a microtubule inhibitor with antiproliferative and antitumor activity that induces apoptosis and cell cycle arrest in the G2/M phase.</p>Formula:C18H19N3O3Purity:99.92%Color and Shape:SolidMolecular weight:325.36MJN68390
CAS:<p>MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.</p>Formula:C24H28ClN3O3Purity:98.86%Color and Shape:SolidMolecular weight:441.95Gallium maltolate
CAS:<p>Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.</p>Formula:C18H15GaO9Purity:99.61% - 99.67%Color and Shape:SolidMolecular weight:445.03SPD304 dihydrochloride
CAS:<p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>Formula:C32H34Cl2F3N3O2Purity:99.25%Color and Shape:SolidMolecular weight:620.53Pyrazoloacridine
CAS:<p>Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.</p>Formula:C19H21N5O3Purity:99.72%Color and Shape:SolidMolecular weight:367.4K-8012
CAS:<p>K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.</p>Formula:C23H23FN4Purity:99.72%Color and Shape:SolidMolecular weight:374.45Cipepofol
CAS:<p>HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.</p>Formula:C14H20OPurity:99.77%Color and Shape:SolidMolecular weight:204.31Perphenazine dihydrochloride
CAS:<p>Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.</p>Formula:C21H28Cl3N3OSPurity:99.67%Color and Shape:SolidMolecular weight:476.89XX-650-23
CAS:<p>XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).</p>Formula:C18H12N2O2Purity:97.01%Color and Shape:SolidMolecular weight:288.3cRIPGBM chloride
CAS:<p>cRIPGBM chloride is a pro-apoptotic derivative found in GBM cancer stem cells with anti-tumor activity, inducing caspase-1-dependent apoptosis.</p>Formula:C26H20ClFN2O2Purity:99.75%Color and Shape:SolidMolecular weight:446.9CCT020312
CAS:<p>CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.</p>Formula:C31H30Br2N4O2Purity:98.63%Color and Shape:SolidMolecular weight:650.4GCN2-IN-1
CAS:<p>GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.</p>Formula:C19H18N10OPurity:99.49% - 99.64%Color and Shape:SolidMolecular weight:402.41TT01001
CAS:<p>TT01001, a mitoNEET agonist, may treat type II diabetes by reducing oxidative stress and preventing neuronal death.</p>Formula:C15H19Cl2N3O2SPurity:99.93%Color and Shape:SolidMolecular weight:376.3H2L5186303
CAS:<p>H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.</p>Formula:C26H20N2O8Purity:98.19%Color and Shape:SolidMolecular weight:488.45Triparanol
CAS:<p>Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1</p>Formula:C27H32ClNO2Purity:99.72%Color and Shape:SolidMolecular weight:438MBM-55
CAS:<p>MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.</p>Formula:C28H27FN6O2Purity:99.83%Color and Shape:SolidMolecular weight:498.55Ciglitazone
CAS:<p>Ciglitazone: potent PPARγ agonist, EC50 3 μM, oral hypoglycemic; reduces insulin, blood pressure, Th17 cells, VEGF; halts gastric cancer growth.</p>Formula:C18H23NO3SPurity:98.23% - 99.59%Color and Shape:White Cyrstalline SolidMolecular weight:333.45Epristeride
CAS:<p>Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.</p>Formula:C25H37NO3Purity:98.12% - >99.99%Color and Shape:SolidMolecular weight:399.57Dasatinib hydrochloride
CAS:<p>Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).</p>Formula:C22H27Cl2N7O2SPurity:99.88% - 99.98%Color and Shape:SolidMolecular weight:524.47GSK-3β inhibitor 3
CAS:<p>GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3</p>Formula:C18H14FNO2SPurity:97.53%Color and Shape:SolidMolecular weight:327.37GSK2593074A
CAS:<p>GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.</p>Formula:C27H23N5OSPurity:99.76%Color and Shape:SolidMolecular weight:465.57HBDDE
CAS:<p>HBDDE inhibits PKCα/γ (IC50: 43/50 μM), favors them over PKCδ/βI/βII, and induces neuronal apoptosis. Derived from ellagic acid.</p>Formula:C16H18O8Purity:97.94%Color and Shape:SolidMolecular weight:338.31EB1
CAS:<p>EB1 is an MNK kinase inhibitor that inhibits cancer cell growth, promotes apoptosis, and inhibits eIF4E phosphorylation.</p>Formula:C18H14N4Purity:99.82%Color and Shape:SolidMolecular weight:286.33Sarmustine
CAS:<p>SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.</p>Formula:C6H11ClN4O3Purity:98.29% - 99.71%Color and Shape:SolidMolecular weight:222.63Mitazalimab
CAS:<p>Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.</p>Purity:95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidSYM 2081
CAS:<p>SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.</p>Formula:C6H11NO4Purity:99.59%Color and Shape:SolidMolecular weight:161.16NecroX-7
CAS:<p>NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.</p>Formula:C24H29N3O3SPurity:98.22%Color and Shape:SolidMolecular weight:439.57Ro 90-7501
CAS:<p>Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.</p>Formula:C20H16N6Purity:97.21% - 99.72%Color and Shape:SolidMolecular weight:340.38DX3-213B
CAS:<p>DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM.</p>Formula:C20H28F2N2O5S2Purity:99.85%Color and Shape:SolidMolecular weight:478.57A09-003
CAS:<p>A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.</p>Formula:C23H26N4OPurity:99.61%Color and Shape:SolidMolecular weight:374.48
