Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
CAS:Formula:C24H28O2Purity:95%Color and Shape:SolidMolecular weight:348.4779Ref: IN-DA00389U
1g253.00€10gTo inquire1mg39.00€25gTo inquire50gTo inquire10mg49.00€50mg52.00€250mg111.00€1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one
CAS:Formula:C16H10O7Purity:98%Color and Shape:SolidMolecular weight:314.2464Norcantharidin, mixture of endo/exo
CAS:Formula:C8H8O4Purity:97%Color and Shape:SolidMolecular weight:168.146717-ODYA
CAS:<p>17-ODYA (Alkynyl Stearic Acid) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.</p>Formula:C18H32O2Purity:98.21%Color and Shape:SolidMolecular weight:280.45Diclofenac sodium
CAS:<p>Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.</p>Formula:C14H10Cl2NNaO2Purity:98.21% - 99.73%Color and Shape:White Or Off-White PowderMolecular weight:318.13Adenosine
CAS:<p>Adenosine (D-Adenosine) is a ribonucleoside. Adenosine has vasodilatory, antiarrhythmic and analgesic effects. Cost-effective and quality-assured.</p>Formula:C10H13N5O4Purity:98.76% - 99.86%Color and Shape:Needles (From Water +3/2) Physical Description White To Off-White Crystalline Powder (Ntp 1992)Molecular weight:267.24Lidocaine hydrochloride
CAS:<p>Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.</p>Formula:C14H23ClN2OPurity:99.81% - 99.92%Color and Shape:White Crystal PowderMolecular weight:270.798Letolizumab
CAS:<p>Letolizumab (BMS-986004) is a dimeric antibody that targets CD40L.</p>Purity:98.8% (SDS-PAGE); 99.2% (SEC-HPLC) - 98.8% (SDS-PAGE); 99.2% (SEC-HPLC)Color and Shape:LiquidSD-36 TFA
<p>SD-36 TFA is a selective and highly efficient STAT3 degrader with a Kd value of about 50 nM.SD-36 has anticancer and antitumor activity, and can break down mutant STAT3 proteins in cells and inhibit STAT3 transcription.SD-36 promotes growth inhibition and induces apoptosis through inhibition of Mcl-1 in gliomas.</p>Formula:C61H63F5N9O14PPurity:98.43% - >99.99%Color and Shape:SolidMolecular weight:1272.17Acetylcysteine
CAS:<p>Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent.</p>Formula:C5H9NO3SPurity:98.01% - >99.99%Color and Shape:Crystals From Water SolidMolecular weight:163.19Sulfasalazine
CAS:<p>Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.</p>Formula:C18H14N4O5SPurity:98.00% - 99.28%Color and Shape:Minute Brownish-Yellow CrystalsMolecular weight:398.39Oxaliplatin
CAS:<p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>Formula:C8H14N2O4PtPurity:97% - 99.93%Color and Shape:SolidMolecular weight:397.29Irbesartan
CAS:<p>Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.</p>Formula:C25H28N6OPurity:99.79% - 99.81%Color and Shape:White Crystalline PowderMolecular weight:428.53Lucatumumab
CAS:<p>Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.</p>Purity:95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Color and Shape:LiquidDiethylstilbestrol
CAS:<p>Diethylstilbestrol (DES) is used in the treatment of menopausal and postmenopausal disorders.</p>Formula:C18H20O2Purity:97.77% - 98.78%Color and Shape:White Crystalline Powder Physical Description Odorless Tasteless White Crystalline Powder (Ntp 1992)Molecular weight:268.35Hexamethonium Bromide
CAS:<p>Hexamethonium Bromide blocks neural nicotinic AChR, poorly absorbed in the gut, doesn't pass the blood-brain barrier.</p>Formula:C12H30Br2N2Purity:99.76%Color and Shape:White Crystalline Powder And AgglomeratesMolecular weight:362.199H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo-
CAS:Formula:C17H14O4Purity:98%Color and Shape:SolidMolecular weight:282.2907Ref: IN-DA0035WP
1g192.00€5gTo inquire25gTo inquire50gTo inquire5mg37.00€25mg54.00€100mg68.00€250mg108.00€Zonisamide
CAS:<p>Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.</p>Formula:C8H8N2O3SPurity:99.05% - 99.9%Color and Shape:Off-White PowderMolecular weight:212.23Tubulin inhibitor 35
CAS:<p>Tubulin inhibitor 35 (Tubulin IN 35) is a topoisomerase I and microtubulin polymerization inhibitor with antitumor activity and induces apoptosis .</p>Formula:C21H21N3OPurity:99.45%Color and Shape:SoildMolecular weight:331.41DefNEtTrp
<p>DefNEtTrp is an iron bis-chelating ligand composed of Def and Trp groups. It demonstrates potent broad-spectrum antiproliferative and cytotoxic effects in cancer cell lines. DefNEtTrp induces apoptosis and ferroptosis, exhibiting cytotoxicity with an IC50 value of 0.77 μM.</p>Formula:C30H27N9O3SColor and Shape:SolidMolecular weight:593.659HPCR
CAS:<p>HPCR exhibits antiproliferative activity against various cancer cells and is involved in apoptosis (apoptosis).</p>Formula:C52H40O12Color and Shape:SolidMolecular weight:856.867KT-253
CAS:<p>KT-253 is a p53 stabilizer and a PROTAC degrader of MDM2 (DC50=0.4 nM). It inhibits the proliferation of cancer cells RS4;11 with an IC50 of 0.3 nM, induces cell cycle arrest in the G2/M phase, and triggers apoptosis. In mouse models, KT-253 demonstrates antitumor activity. (Pink: ligand for target protein MDM2 ligand 4; Black: linker; Blue: ligand for E3 ligase cereblon)</p>Formula:C48H52Cl2FN7O6Color and Shape:SolidMolecular weight:912.874Antioxidant agent-20
<p>Antioxidant agent-20 (Compound 3d) exhibits potent anti-inflammatory and antioxidant activities. It reduces reactive oxygen species (ROS) and apoptosis in a dose-dependent manner. Antioxidant agent-20 demonstrates photoprotective effects on UVB-exposed human skin keratinocytes (HaCaT) (IC50=5.13 µM) by activating Nrf2/HO-1 signaling and inhibiting the NF-κB pathway.</p>Formula:C18H24O4Color and Shape:SolidMolecular weight:304.381Mitochondria modulator-2
<p>Mitochondria modulator-2 (Compound Ir1) induces depolarization of the mitochondrial membrane potential, generates reactive oxygen species (ROS), inhibits the migration of A549 cells, causes cell cycle arrest at the G2/M phase, and triggers apoptosis in A549 cells.</p>Formula:C63H50F12IrN6OP3Color and Shape:SolidMolecular weight:1420.23MG-277
<p>MG-277 is a molecular glue compound transformed from PROTAC degradation agent, MG-277 potently inhibits tumor cell growth in a p53-independent manner.</p>Formula:C41H42Cl2FN5O5Purity:98%Color and Shape:SolidMolecular weight:774.71CQ-ER
<p>CQ-ER is a Coumarin-quinazolinone-based photosensitizer targeting the endoplasmic reticulum (ER). It induces ferroptosis, thereby enhancing photodynamic therapy (PDT).</p>Formula:C33H33N7O6SColor and Shape:SolidMolecular weight:655.72Gliotoxin
CAS:<p>Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.</p>Formula:C13H14N2O4S2Purity:98%Color and Shape:SolidMolecular weight:326.39TAT-GluN2BCTM
CAS:<p>TAT-GluN2BCTM is a membrane-permeable peptide that selectively targets active DAPK1 (Death-associated protein kinase 1) for lysosomal degradation, thereby</p>Formula:C224H374N86O54Purity:98%Color and Shape:SolidMolecular weight:5135.91LY3415244
<p>LY3415244 is a human bispecific antibody (bsAb) that targets B7-H1/PD-L1/CD274 and TIM-3/HAVCR2/CD366. This compound is applicable in the study of advanced solid tumors.</p>Color and Shape:Odour LiquidCholicamideβ
<p>Cholicamideβ (compound 6), a self-assembling small molecule cancer vaccine adjuvant, forms low cytotoxicity virus-like particles and upon binding to peptide</p>Formula:C55H94N2O6Purity:98%Color and Shape:SolidMolecular weight:879.34Dapirolizumab
<p>Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.</p>Purity:>95%Color and Shape:LiquidMolecular weight:145.5 kDaTRAP-1
<p>TRAP-1 (XJZ-06-462) is a p53 transcription activator that effectively activates mutant p53 and triggers the transcription of p53 target genes. In the p53Y220C pancreatic cell line, TRAP-1 rapidly upregulates p21 and other p53 target genes. TRAP-1 also inhibits cell proliferation, exhibiting IC50 values of 3.94 μM and 0.531 μM in BxPC-3 and A549 cell lines, respectively. Additionally, TRAP-1 modulates autophagy in lung cancer cells and provides protection against oxidative stress and apoptosis.</p>Formula:C57H66ClF3N11O3PSColor and Shape:SolidMolecular weight:1108.69Psalmotoxin 1
CAS:<p>Psalmotoxin 1 is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker.</p>Formula:C200H312N62O57S6Purity:98%Color and Shape:SolidMolecular weight:4689.41SP3N hydrochloride
<p>SP3N hydrochloride is a specific degrader of the prolyl isomerase (FKBP12). Its alkylamine moiety is metabolized into an active aldehyde (SP3CHO), which recruits the SCFFBXO22 ligase for the degradation of FKBP12. SP3N hydrochloride is applicable in cancer research.</p>Color and Shape:Odour SolidSuramin
CAS:<p>Suramin is an RdRp and PTPase inhibitor with anti-parasitic, anti-tumor, and anti-angiogenic activities, inhibiting sirtuins and DNA topoisomerase II.</p>Formula:C51H40N6O23S6Purity:99.80%Color and Shape:SolidMolecular weight:1297.28Pyridinium bisretinoid A2E TFA
CAS:<p>Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates</p>Formula:C44H58F3NO3Purity:98%Color and Shape:SolidMolecular weight:705.93fac-[Re(CO)3(L6)(H2O)][NO3]
<p>Compound 6, fac-[Re(CO)3(L6)(H2O)][NO3], a rhenium(I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function.</p>Formula:C24H14N5O7ReSPurity:98%Color and Shape:SolidMolecular weight:702.67RET ligand-3
<p>RETligand-3 is the ligand for PROTAC QZ2135, which targets RET.</p>Formula:C38H42N10O3Color and Shape:SolidMolecular weight:686.81Anticancer agent 133
<p>Compound Rh2 (Anticancer agent 133) is a cytotoxic and antimetastatic agent that induces cell cycle arrest, apoptosis, and autophagy.</p>Formula:C24H19Cl3N5ORhPurity:98%Color and Shape:SolidMolecular weight:602.71PTD-p65-P1 Peptide
<p>PTD-p65-P1: a NF-kappaB inhibitor blocking activation from multiple inflammatory stimuli.</p>Formula:C168H275N57O44SPurity:98%Color and Shape:SolidMolecular weight:3829.5Thalidomide-PEG2-C2-NH2 hydrochloride
CAS:<p>Thalidomide-based cereblon ligand with 2-unit PEG linker for PROTAC, in hydrochloride form.</p>Formula:C19H25ClN4O6Purity:98%Color and Shape:SolidMolecular weight:440.88p38-α MAPK-IN-8
<p>p38-α MAPK-IN-8 (Compound 13) is a lipophilic cationic derivative. It exhibits cytotoxicity toward various tumor cells, inducing cell cycle arrest and apoptosis, as well as increasing reactive oxygen species (ROS) production and causing mitochondrial membrane potential depolarization. Its antitumor activity may be related to the p38α MAPK pathway, making it a potential candidate for cancer research.</p>Formula:C49H62BrO4PColor and Shape:SolidMolecular weight:825.892Antimycin A2c
<p>Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer.</p>Formula:C28H40N2O9Purity:98%Color and Shape:SolidMolecular weight:548.63BK60106
<p>BK60106 is a selective and direct inhibitor of the transmembrane protein CD99, which causes cell death in Ewing Sarcoma cells.</p>Formula:C15H15FN6O3Purity:99.30% - >99.99%Color and Shape:SolidMolecular weight:346.32APG-1387
CAS:<p>APG-1387 inhibits IAPs, degrades cIAP1/2, XIAP, boosts chemosensitivity, and induces apoptosis in NPC.</p>Formula:C60H72N10O10S2Color and Shape:SolidMolecular weight:1157.41ChoKα inhibitor-5
<p>ChoKα Inhibitor-5, a sulfur-containing choline kinase inhibitor, effectively inhibits HChoKα1 with an IC50 value of 0.64 μM and induces apoptosis.</p>Formula:C54H68Br2N4S4Color and Shape:SolidMolecular weight:1061.21Conglobatin
CAS:<p>Conglobatin is a natural product for research related to life sciences. The catalog number is T36494 and the CAS number is 72263-05-9.</p>Formula:C28H38N2O6Color and Shape:SolidMolecular weight:498.62JNK-1-IN-3
CAS:<p>JNK-1-IN-3 (Compound 9e) downregulates JNK1 and phosphorylated JNK1, reduces c-Jun and c-Fos expression in tumours, and restores p53 activity.</p>Formula:C19H17FN4O3Purity:97.551%Color and Shape:SolidMolecular weight:368.36AS-99 free base
CAS:<p>AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity.</p>Formula:C27H30F3N5O3S2Color and Shape:SolidMolecular weight:593.68
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