Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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Pinosylvin
CAS:<p>Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.</p>Formula:C14H12O2Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:212.24M50054
CAS:<p>Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.</p>Formula:C13H16O4Purity:97.8%Color and Shape:SolidMolecular weight:236.26BI-847325
CAS:<p>BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.</p>Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:SolidMolecular weight:464.56BI 2536
CAS:<p>BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.</p>Formula:C28H39N7O3Purity:98% - 99.88%Color and Shape:SolidMolecular weight:521.65Copanlisib
CAS:<p>Copanlisib (BAY 80-6946), a PI3K inhibitor, may block tumor growth and improve cancer treatment efficacy.</p>Formula:C23H28N8O4Purity:99% - 99.88%Color and Shape:SolidMolecular weight:480.52Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Formula:C15H11NSPurity:98.00%Color and Shape:SolidMolecular weight:237.32Terrestrosin D
CAS:<p>Terrestrosin D triggers apoptosis, halts cell cycles, and blocks angiogenesis in tumor cells, displaying anti-cancer effects.</p>Formula:C50H80O23Purity:99.92% - 99.96%Color and Shape:SolidMolecular weight:1049.16Ganetespib
CAS:<p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>Formula:C20H20N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:364.4Aminopurvalanol A
CAS:<p>Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1</p>Formula:C19H26ClN7OPurity:99.73%Color and Shape:SolidMolecular weight:403.91Apomine
CAS:<p>Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂，可在体外促进骨髓瘤细胞的凋亡，并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。</p>Formula:C28H52O7P2Purity:>99.99%Color and Shape:SolidMolecular weight:562.66TBHQ
CAS:<p>TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.</p>Formula:C10H14O2Purity:99.17% - 99.53%Color and Shape:White Solid PowderMolecular weight:166.22Ginsenoside Rh2
CAS:<p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>Formula:C36H62O8Purity:99.20% - 99.76%Color and Shape:White PowderMolecular weight:622.87Ginsenoside F2
CAS:<p>Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.</p>Formula:C42H72O13Purity:99.04% - 99.3%Color and Shape:SolidMolecular weight:785.01HA14-1
CAS:<p>HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 μM).</p>Formula:C17H17BrN2O5Purity:95.07% - 98%Color and Shape:SolidMolecular weight:409.23LCL161
CAS:<p>LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.</p>Formula:C26H33FN4O3SPurity:99.13% - 99.87%Color and Shape:SolidMolecular weight:500.63Mocetinostat
CAS:<p>Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.</p>Formula:C23H20N6OPurity:99% - 99.21%Color and Shape:SolidMolecular weight:396.44AG1024
CAS:<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Formula:C14H13BrN2OPurity:98% - 99.37%Color and Shape:SolidMolecular weight:305.17Sertaconazole
CAS:<p>Sertaconazole is a broad-spectrum antifungal.</p>Formula:C20H15Cl3N2OSPurity:99.483%Color and Shape:SolidMolecular weight:437.77Rigosertib
CAS:<p>Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.</p>Formula:C21H25NO8SPurity:99.53%Color and Shape:SolidMolecular weight:451.49PI-103
CAS:<p>PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).</p>Formula:C19H16N4O3Purity:97.79% - 99.3%Color and Shape:SolidMolecular weight:348.36ML311
CAS:<p>ML311 is a selective inhibitor of the Mcl-1/Bim interaction.</p>Formula:C23H24F3N3OPurity:99.75%Color and Shape:SolidMolecular weight:415.45Asiaticoside
CAS:<p>Asiaticoside, in Centella asiatica, may treat wounds/burns.</p>Formula:C48H78O19Purity:98% - 99.96%Color and Shape:PowderMolecular weight:959.12SC66
CAS:<p>SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 μg/ml, at 72 h).</p>Formula:C18H16N2OPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:276.33Rhosin hydrochloride
CAS:<p>Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.</p>Formula:C20H20Cl2N6OPurity:97.33% - 98.92%Color and Shape:SolidMolecular weight:431.318NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Formula:C45H82N11O17P3Purity:98.73% - 99.05%Color and Shape:SolidMolecular weight:1142.12Idasanutlin
CAS:<p>Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).</p>Formula:C31H29Cl2F2N3O4Purity:99.13% - 99.88%Color and Shape:SolidMolecular weight:616.48CPTH2
CAS:<p>CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.</p>Formula:C14H14ClN3SPurity:99.81%Color and Shape:SolidMolecular weight:291.8ZMC1
CAS:<p>NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).</p>Formula:C11H14N4SPurity:98.97% - 99.76%Color and Shape:SolidMolecular weight:234.32RAD51 Inhibitor B02
CAS:<p>RAD51 Inhibitor B02 (B02) (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.</p>Formula:C22H17N3OPurity:99.72% - 99.89%Color and Shape:SolidMolecular weight:339.39Bendamustine
CAS:<p>Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia</p>Formula:C16H21Cl2N3O2Purity:≥98%Color and Shape:SolidMolecular weight:358.26Sertaconazole nitrate
CAS:<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Formula:C20H15Cl3N2OS·HNO3Purity:98.66% - 99.65%Color and Shape:SolidMolecular weight:500.78Almorexant
CAS:<p>Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.</p>Formula:C29H31F3N2O3Purity:97.75% - 98.02%Color and Shape:SolidMolecular weight:512.56Grape Seed Extract
CAS:<p>Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites.</p>Formula:C32H30O11Purity:98%Color and Shape:SolidMolecular weight:590.581CVT-11127
CAS:<p>CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.</p>Formula:C25H23Cl2N5O3Purity:98.32%Color and Shape:SolidMolecular weight:512.39N-Ethylmaleimide
CAS:<p>N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor. Cost-effective and quality-assured.</p>Formula:C6H7NO2Purity:99.50%Color and Shape:White SolidMolecular weight:125.13Cucurbitacin IIA
CAS:<p>1.</p>Formula:C32H50O8Purity:98.62% - 99.87%Color and Shape:SolidMolecular weight:562.73OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:443.44Tanespimycin
CAS:<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Formula:C31H43N3O8Purity:99.07% - 99.83%Color and Shape:Dark Purple SolidMolecular weight:585.692-tert-Butyl-1,4-benzoquinone
CAS:<p>TBQ, a BHA metabolite, activates Nrf2 and S-arylates Keap1 in RAW264.7 cells.</p>Formula:C10H12O2Purity:97.19%Color and Shape:SolidMolecular weight:164.2Quizartinib
CAS:<p>Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.</p>Formula:C29H32N6O4SPurity:98% - 99.42%Color and Shape:SolidMolecular weight:560.67Caudatin
CAS:<p>Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.</p>Formula:C28H42O7Purity:98.83% - 99.9%Color and Shape:SolidMolecular weight:490.63Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Formula:C26H44NNaO6SPurity:98.23% - 99.45%Color and Shape:White To Off-White PowderMolecular weight:521.68GSK-J4
CAS:<p>GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.</p>Formula:C24H27N5O2Purity:98.24% - 99.98%Color and Shape:SolidMolecular weight:417.5Angelicin
CAS:<p>Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.</p>Formula:C11H6O3Purity:99.86% - 99.89%Color and Shape:White SolidMolecular weight:186.16Fimasartan
CAS:<p>Fimasartan (BR-A-657), an ARB, treats hypertension and heart failure; safe with hydrochlorothiazide.</p>Formula:C27H31N7OSPurity:98.96%Color and Shape:SolidMolecular weight:501.65Lenalidomide hemihydrate
CAS:<p>Lenalidomide hemihydrate inhibits TNF-α (IC50=13nM) and binds CRBN/DDB1 complexes.</p>Formula:C13H13N3O3H2OPurity:96.22%Color and Shape:SolidMolecular weight:268.28ASTX660
CAS:<p>Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.</p>Formula:C30H42FN5O3Purity:98.33% - 99.85%Color and Shape:SolidMolecular weight:539.68Palomid 529
CAS:<p>Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.</p>Formula:C24H22O6Purity:98.40% - 98.59%Color and Shape:SolidMolecular weight:406.43BI-6C9
CAS:<p>BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.</p>Formula:C23H25N3O4S2Purity:98.39%Color and Shape:SolidMolecular weight:471.59
