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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 5592 products of "Apoptosis"

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  • Nafamostat mesylate

    CAS:
    <p>Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis</p>
    Formula:C19H17N5O2·2CH4O3S
    Purity:97.36% - 99.76%
    Color and Shape:Tan To Pale Orange Solid
    Molecular weight:539.58
  • Benidipine

    CAS:
    <p>Benidipine: potent oral calcium blocker, boosts nitric oxide synthase, enhances coronary flow, protects heart cells post-ischemia.</p>
    Formula:C28H31N3O6
    Color and Shape:Solid
    Molecular weight:505.56
  • Etidronic acid

    CAS:
    <p>Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.</p>
    Formula:C2H8O7P2
    Purity:99.93% - ≥95%
    Color and Shape:Liquid Syrup
    Molecular weight:206.03
  • TCS7010

    CAS:
    <p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>
    Formula:C31H31ClFN7O2
    Purity:98.49% - 99.62%
    Color and Shape:Solid
    Molecular weight:588.07
  • Luminespib

    CAS:
    <p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C26H31N3O5
    Purity:98% - 99.25%
    Color and Shape:Solid
    Molecular weight:465.54
  • Difurazon hydrochloride

    CAS:
    <p>Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.</p>
    Formula:C14H13ClN6O6
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:396.74
  • dBET6

    CAS:
    <p>dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.</p>
    Formula:C42H45ClN8O7S
    Purity:97.57% - 99.12%
    Color and Shape:Solid
    Molecular weight:841.37
  • Thalidomide-NH-C4-NH-Boc

    CAS:
    <p>Thalidomide-NH-C4-NH-Boc is a cereblon-based E3 ligase ligand-linker for PROTACs.</p>
    Formula:C22H28N4O6
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:444.48
  • Thalidomide-4-OH

    CAS:
    <p>Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.</p>
    Formula:C13H10N2O5
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:274.23
  • Dinaciclib

    CAS:
    <p>Dinaciclib (SCH 727965) is a CDK inhibitor that selectively inhibits CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM).</p>
    Formula:C21H28N6O2
    Purity:98.21% - 99.75%
    Color and Shape:Solid
    Molecular weight:396.49
  • GSK778 hydrochloride

    CAS:
    <p>GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.</p>
    Formula:C30H34ClN5O3
    Purity:97.26% - 98.35%
    Color and Shape:Solid
    Molecular weight:548.08
  • Astragalin

    CAS:
    <p>Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid.</p>
    Formula:C21H20O11
    Purity:98.8% - ≥95%
    Color and Shape:Solid
    Molecular weight:448.38
  • PRLX-93936

    CAS:
    <p>PRLX-93936 is a selective Ras pathway protein inhibitor that modulates RAS/JNK pathway-associated protein phosphorylation, anticancer activity.</p>
    Formula:C21H24N4O2
    Color and Shape:Solid
    Molecular weight:364.44
  • Desciclovir

    CAS:
    <p>Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.</p>
    Formula:C8H11N5O2
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:209.21
  • Phellamurin

    CAS:
    <p>Phellamurin blocks intestinal P-glycoprotein dose-dependently and it seriously interacts with cyclosporin; coadministration should be avoided.</p>
    Formula:C26H30O11
    Purity:97.91%
    Color and Shape:Solid
    Molecular weight:518.51
  • PNU-74654

    CAS:
    <p>PNU 74654 blocks β-catenin/Tcf4, disrupting Wnt signaling (Kd = 450 nM).</p>
    Formula:C19H16N2O3
    Purity:97.27%
    Color and Shape:Solid
    Molecular weight:320.34
  • Pracinostat

    CAS:
    <p>Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral</p>
    Formula:C20H30N4O2
    Purity:99.15% - 99.67%
    Color and Shape:Solid
    Molecular weight:358.48
  • 2-Hydroxychalcone

    CAS:
    <p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>
    Formula:C15H12O2
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:224.25
  • UC2288

    CAS:
    <p>UC2288, a Sorafenib-based p21 attenuator, reduces p21 levels without affecting its stability.</p>
    Formula:C20H18ClF6N3O2
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:481.82
  • Brassinolide

    CAS:
    <p>Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.</p>
    Formula:C28H48O6
    Purity:98% - 99.189%
    Color and Shape:Off-White Solid
    Molecular weight:480.68
  • 2-HBA

    CAS:
    <p>2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.</p>
    Formula:C17H14O3
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:266.29
  • GMB-475

    CAS:
    <p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>
    Formula:C43H46F3N7O7S
    Purity:98.78% - >99.99%
    Color and Shape:Solid
    Molecular weight:861.93
  • Ginkgetin

    CAS:
    <p>Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.</p>
    Formula:C32H22O10
    Purity:98.63% - 99.94%
    Color and Shape:Solid
    Molecular weight:566.51
  • Indirubin

    CAS:
    <p>Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.</p>
    Formula:C16H10N2O2
    Purity:97.21% - 99.74%
    Color and Shape:Reddish-Violet Powder
    Molecular weight:262.26
  • Liproxstatin-1 hydrochloride

    CAS:
    <p>Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].</p>
    Formula:C19H22Cl2N4
    Color and Shape:Solid
    Molecular weight:377.31
  • Valproic Acid

    CAS:
    <p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>
    Formula:C8H16O2
    Purity:97.78% - 99%
    Color and Shape:Colourless To Pale Yellow Liquid Viscous
    Molecular weight:144.21
  • MK-2206

    CAS:
    <p>MK-2206: selective Akt inhibitor, oral, targets Akt1, Akt2, Akt3; effective in breast cancer, PIK3CA mutants, PTEN-deficient cells.</p>
    Formula:C25H22ClN5O
    Color and Shape:Solid
    Molecular weight:443.94
  • GSK1059615

    CAS:
    <p>GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.</p>
    Formula:C18H11N3O2S
    Purity:99.3% - ≥95%
    Color and Shape:Solid
    Molecular weight:333.36
  • Millepachine

    CAS:
    <p>Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.</p>
    Formula:C22H22O4
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:350.41
  • Eltrombopag

    CAS:
    <p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>
    Formula:C25H22N4O4
    Purity:99.27%
    Color and Shape:Orange To Red Solid
    Molecular weight:442.47
  • Milademetan free base

    CAS:
    <p>Milademetan (DS-3032b) is a potent MDM2 inhibitor, potentially blocking cancer growth by targeting p53 protein.</p>
    Formula:C37H42Cl2FN5O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:790.73
  • STF-118804

    CAS:
    <p>STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 &lt;10 nM.</p>
    Formula:C25H23N3O4S
    Purity:98.66%
    Color and Shape:Solid
    Molecular weight:461.53
  • Methoxychlor

    CAS:
    <p>Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.</p>
    Formula:C16H15Cl3O2
    Purity:98.82% - ≥95%
    Color and Shape:Colorless Crystals (Technical Grey Powder) To The Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment If
    Molecular weight:345.65
  • [6]-Gingerol

    CAS:
    <p>[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.</p>
    Formula:C17H26O4
    Purity:98% - 99.66%
    Color and Shape:Light Yellow Oiliness
    Molecular weight:294.39
  • DIM-C-pPhCO2Me

    CAS:
    <p>DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist.</p>
    Formula:C25H20N2O2
    Purity:99.55% - 99.86%
    Color and Shape:Solid
    Molecular weight:380.44
  • Epoxiconazole

    CAS:
    <p>Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation.</p>
    Formula:C17H13ClFN3O
    Purity:98.57%
    Color and Shape:Solid Powder
    Molecular weight:329.76
  • SKI II

    CAS:
    <p>SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.</p>
    Formula:C15H11ClN2OS
    Purity:99.34% - 99.93%
    Color and Shape:Solid
    Molecular weight:302.78
  • Diffractaic Acid

    CAS:
    <p>Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.</p>
    Formula:C20H22O7
    Purity:99.81% - 99.87%
    Color and Shape:Solid
    Molecular weight:374.38
  • NSC 95397

    CAS:
    <p>NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).</p>
    Formula:C14H14O4S2
    Purity:98.66%
    Color and Shape:Solid
    Molecular weight:310.39
  • Glyphosate

    CAS:
    <p>Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.</p>
    Formula:C3H8NO5P
    Purity:99.12% - 99.91%
    Color and Shape:White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)
    Molecular weight:169.07
  • S-trityl-L-Cysteine

    CAS:
    <p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>
    Formula:C22H21NO2S
    Purity:97.02%
    Color and Shape:Almost White To Light Yellow Granular Powder
    Molecular weight:363.47
  • Daphnetin

    CAS:
    <p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>
    Formula:C9H6O4
    Purity:97.47% - 99.8%
    Color and Shape:Solid
    Molecular weight:178.14
  • SR-4835

    CAS:
    <p>SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (</p>
    Formula:C21H20Cl2N10O
    Purity:98.09% - >99.99%
    Color and Shape:Solid
    Molecular weight:499.36
  • kauran-16,17-diol

    CAS:
    <p>Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7</p>
    Formula:C20H34O2
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:306.48
  • Tanespimycin

    CAS:
    <p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>
    Formula:C31H43N3O8
    Purity:99.07% - 99.83%
    Color and Shape:Dark Purple Solid
    Molecular weight:585.69
  • LRRK2-IN-1

    CAS:
    <p>LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.</p>
    Formula:C31H38N8O3
    Purity:98% - 98.82%
    Color and Shape:Solid
    Molecular weight:570.69
  • HO-3867

    CAS:
    <p>HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.</p>
    Formula:C28H30F2N2O2
    Purity:91.18% - 99.21%
    Color and Shape:Solid
    Molecular weight:464.55
  • BAM7

    CAS:
    <p>BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).</p>
    Formula:C21H19N5O2S
    Purity:98.51% - 98.68%
    Color and Shape:Solid
    Molecular weight:405.47
  • Carfilzomib

    CAS:
    <p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>
    Formula:C40H57N5O7
    Purity:99.6% - 99.84%
    Color and Shape:Solid
    Molecular weight:719.91
  • TW-37

    CAS:
    <p>TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).</p>
    Formula:C33H35NO6S
    Purity:97.06% - ≥95%
    Color and Shape:Solid
    Molecular weight:573.7