
Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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Nafamostat mesylate
CAS:<p>Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis</p>Formula:C19H17N5O2·2CH4O3SPurity:97.36% - 99.76%Color and Shape:Tan To Pale Orange SolidMolecular weight:539.58Benidipine
CAS:<p>Benidipine: potent oral calcium blocker, boosts nitric oxide synthase, enhances coronary flow, protects heart cells post-ischemia.</p>Formula:C28H31N3O6Color and Shape:SolidMolecular weight:505.56Etidronic acid
CAS:<p>Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.</p>Formula:C2H8O7P2Purity:99.93% - ≥95%Color and Shape:Liquid SyrupMolecular weight:206.03TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Formula:C31H31ClFN7O2Purity:98.49% - 99.62%Color and Shape:SolidMolecular weight:588.07Luminespib
CAS:<p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C26H31N3O5Purity:98% - 99.25%Color and Shape:SolidMolecular weight:465.54Difurazon hydrochloride
CAS:<p>Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.</p>Formula:C14H13ClN6O6Purity:98.51%Color and Shape:SolidMolecular weight:396.74dBET6
CAS:<p>dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.</p>Formula:C42H45ClN8O7SPurity:97.57% - 99.12%Color and Shape:SolidMolecular weight:841.37Thalidomide-NH-C4-NH-Boc
CAS:<p>Thalidomide-NH-C4-NH-Boc is a cereblon-based E3 ligase ligand-linker for PROTACs.</p>Formula:C22H28N4O6Purity:98.87%Color and Shape:SolidMolecular weight:444.48Thalidomide-4-OH
CAS:<p>Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.</p>Formula:C13H10N2O5Purity:99.59%Color and Shape:SolidMolecular weight:274.23Dinaciclib
CAS:<p>Dinaciclib (SCH 727965) is a CDK inhibitor that selectively inhibits CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM).</p>Formula:C21H28N6O2Purity:98.21% - 99.75%Color and Shape:SolidMolecular weight:396.49GSK778 hydrochloride
CAS:<p>GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.</p>Formula:C30H34ClN5O3Purity:97.26% - 98.35%Color and Shape:SolidMolecular weight:548.08Astragalin
CAS:<p>Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid.</p>Formula:C21H20O11Purity:98.8% - ≥95%Color and Shape:SolidMolecular weight:448.38PRLX-93936
CAS:<p>PRLX-93936 is a selective Ras pathway protein inhibitor that modulates RAS/JNK pathway-associated protein phosphorylation, anticancer activity.</p>Formula:C21H24N4O2Color and Shape:SolidMolecular weight:364.44Desciclovir
CAS:<p>Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.</p>Formula:C8H11N5O2Purity:99.54%Color and Shape:SolidMolecular weight:209.21Phellamurin
CAS:<p>Phellamurin blocks intestinal P-glycoprotein dose-dependently and it seriously interacts with cyclosporin; coadministration should be avoided.</p>Formula:C26H30O11Purity:97.91%Color and Shape:SolidMolecular weight:518.51PNU-74654
CAS:<p>PNU 74654 blocks β-catenin/Tcf4, disrupting Wnt signaling (Kd = 450 nM).</p>Formula:C19H16N2O3Purity:97.27%Color and Shape:SolidMolecular weight:320.34Pracinostat
CAS:<p>Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral</p>Formula:C20H30N4O2Purity:99.15% - 99.67%Color and Shape:SolidMolecular weight:358.482-Hydroxychalcone
CAS:<p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>Formula:C15H12O2Purity:99.6%Color and Shape:SolidMolecular weight:224.25UC2288
CAS:<p>UC2288, a Sorafenib-based p21 attenuator, reduces p21 levels without affecting its stability.</p>Formula:C20H18ClF6N3O2Purity:99.75%Color and Shape:SolidMolecular weight:481.82Brassinolide
CAS:<p>Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.</p>Formula:C28H48O6Purity:98% - 99.189%Color and Shape:Off-White SolidMolecular weight:480.682-HBA
CAS:<p>2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.</p>Formula:C17H14O3Purity:99.76%Color and Shape:SolidMolecular weight:266.29GMB-475
CAS:<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Formula:C43H46F3N7O7SPurity:98.78% - >99.99%Color and Shape:SolidMolecular weight:861.93Ginkgetin
CAS:<p>Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.</p>Formula:C32H22O10Purity:98.63% - 99.94%Color and Shape:SolidMolecular weight:566.51Indirubin
CAS:<p>Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.</p>Formula:C16H10N2O2Purity:97.21% - 99.74%Color and Shape:Reddish-Violet PowderMolecular weight:262.26Liproxstatin-1 hydrochloride
CAS:<p>Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].</p>Formula:C19H22Cl2N4Color and Shape:SolidMolecular weight:377.31Valproic Acid
CAS:<p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>Formula:C8H16O2Purity:97.78% - 99%Color and Shape:Colourless To Pale Yellow Liquid ViscousMolecular weight:144.21MK-2206
CAS:<p>MK-2206: selective Akt inhibitor, oral, targets Akt1, Akt2, Akt3; effective in breast cancer, PIK3CA mutants, PTEN-deficient cells.</p>Formula:C25H22ClN5OColor and Shape:SolidMolecular weight:443.94GSK1059615
CAS:<p>GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.</p>Formula:C18H11N3O2SPurity:99.3% - ≥95%Color and Shape:SolidMolecular weight:333.36Millepachine
CAS:<p>Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.</p>Formula:C22H22O4Purity:99.73%Color and Shape:SolidMolecular weight:350.41Eltrombopag
CAS:<p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>Formula:C25H22N4O4Purity:99.27%Color and Shape:Orange To Red SolidMolecular weight:442.47Milademetan free base
CAS:<p>Milademetan (DS-3032b) is a potent MDM2 inhibitor, potentially blocking cancer growth by targeting p53 protein.</p>Formula:C37H42Cl2FN5O7SPurity:98%Color and Shape:SolidMolecular weight:790.73STF-118804
CAS:<p>STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.</p>Formula:C25H23N3O4SPurity:98.66%Color and Shape:SolidMolecular weight:461.53Methoxychlor
CAS:<p>Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.</p>Formula:C16H15Cl3O2Purity:98.82% - ≥95%Color and Shape:Colorless Crystals (Technical Grey Powder) To The Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment IfMolecular weight:345.65[6]-Gingerol
CAS:<p>[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.</p>Formula:C17H26O4Purity:98% - 99.66%Color and Shape:Light Yellow OilinessMolecular weight:294.39DIM-C-pPhCO2Me
CAS:<p>DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist.</p>Formula:C25H20N2O2Purity:99.55% - 99.86%Color and Shape:SolidMolecular weight:380.44Epoxiconazole
CAS:<p>Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation.</p>Formula:C17H13ClFN3OPurity:98.57%Color and Shape:Solid PowderMolecular weight:329.76SKI II
CAS:<p>SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.</p>Formula:C15H11ClN2OSPurity:99.34% - 99.93%Color and Shape:SolidMolecular weight:302.78Diffractaic Acid
CAS:<p>Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.</p>Formula:C20H22O7Purity:99.81% - 99.87%Color and Shape:SolidMolecular weight:374.38NSC 95397
CAS:<p>NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).</p>Formula:C14H14O4S2Purity:98.66%Color and Shape:SolidMolecular weight:310.39Glyphosate
CAS:<p>Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.</p>Formula:C3H8NO5PPurity:99.12% - 99.91%Color and Shape:White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)Molecular weight:169.07S-trityl-L-Cysteine
CAS:<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Formula:C22H21NO2SPurity:97.02%Color and Shape:Almost White To Light Yellow Granular PowderMolecular weight:363.47Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14SR-4835
CAS:<p>SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (</p>Formula:C21H20Cl2N10OPurity:98.09% - >99.99%Color and Shape:SolidMolecular weight:499.36kauran-16,17-diol
CAS:<p>Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7</p>Formula:C20H34O2Purity:99.93%Color and Shape:SolidMolecular weight:306.48Tanespimycin
CAS:<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Formula:C31H43N3O8Purity:99.07% - 99.83%Color and Shape:Dark Purple SolidMolecular weight:585.69LRRK2-IN-1
CAS:<p>LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.</p>Formula:C31H38N8O3Purity:98% - 98.82%Color and Shape:SolidMolecular weight:570.69HO-3867
CAS:<p>HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.</p>Formula:C28H30F2N2O2Purity:91.18% - 99.21%Color and Shape:SolidMolecular weight:464.55BAM7
CAS:<p>BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).</p>Formula:C21H19N5O2SPurity:98.51% - 98.68%Color and Shape:SolidMolecular weight:405.47Carfilzomib
CAS:<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Formula:C40H57N5O7Purity:99.6% - 99.84%Color and Shape:SolidMolecular weight:719.91TW-37
CAS:<p>TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).</p>Formula:C33H35NO6SPurity:97.06% - ≥95%Color and Shape:SolidMolecular weight:573.7
