Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(116 products)
- PDK(9 products)
- PERK(24 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(65 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6114 products of "Apoptosis"
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Tomivosertib HCl
CAS:Tomivosertib (eFT508) is a MNK1/2 inhibitor that blocks eIF4E phosphorylation, hindering tumor growth and immune signaling.Formula:C17H21ClN6O2Color and Shape:SolidMolecular weight:376.845Thalidomide-NH-CH2-COOH
CAS:Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing aFormula:C15H13N3O6Purity:96.3800%Color and Shape:SolidMolecular weight:331.28Trolox
CAS:Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.Formula:C14H18O4Purity:98.90% - 99.90%Color and Shape:White To Fainly Beige Crystalline PowderMolecular weight:250.29Thalidomide-NH-PEG1-NH2 hydrochloride
CAS:Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-Formula:C17H21ClN4O5Purity:97.13%Color and Shape:SolidMolecular weight:396.83Grape Seed Extract
CAS:Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites.Formula:C32H30O11Purity:98%Color and Shape:SolidMolecular weight:590.581Ivachtin
CAS:Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining
Formula:C20H21N3O7SPurity:99.74%Color and Shape:SolidMolecular weight:447.46Afimetoran
CAS:Afimetoran (BMS-986256) is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.Formula:C26H32N6OPurity:99.81% - 99.94%Color and Shape:SolidMolecular weight:444.57Ref: TM-T39654
1mg87.00€5mg177.00€10mg295.00€25mg492.00€50mg688.00€100mg964.00€1mL*10mM (DMSO)203.00€CHIR-124
CAS:CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.Formula:C23H22ClN5OPurity:96.33% - 98.35%Color and Shape:SolidMolecular weight:419.91Ref: TM-T6350
1mg39.00€2mg49.00€5mg77.00€10mg99.00€25mg161.00€50mg227.00€100mg339.00€1mL*10mM (DMSO)82.00€OTS514
CAS:OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor.Formula:C21H20N2O2SPurity:99.62%Color and Shape:SolidMolecular weight:364.46Ref: TM-T4134L
1mg65.00€5mg144.00€10mg222.00€25mg394.00€50mg532.00€100mg743.00€200mg982.00€1mL*10mM (DMSO)152.00€Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formula:C21H22O8Purity:98.65% - 99.76%Color and Shape:SolidMolecular weight:402.39Ref: TM-T2834
5mg54.00€10mg84.00€25mg117.00€50mg159.00€100mg251.00€200mg371.00€500mg620.00€1mL*10mM (DMSO)56.00€Chromium picolinate
CAS:Chromium picolinate causes DNA damage and mutation. It is an activator of p38.Formula:C18H12CrN3O6Purity:99.64%Color and Shape:Violet-Red Crystalline PowderMolecular weight:418.30Ganoderic acid A
CAS:Ganoderic acid A fights tumors, suppresses gene regulators, induces cancer cell death, and enhances cisplatin efficacy.Formula:C30H44O7Purity:99.31% - ≥95%Color and Shape:SolidMolecular weight:516.67Ref: TM-T6S1141
1mg44.00€5mg92.00€10mg152.00€25mg236.00€50mg354.00€100mg518.00€1mL*10mM (DMSO)104.00€ZZW-115 hydrochloride
CAS:ZZW-115 hydrochloride inhibits the activity of NUPR1.Formula:C24H34Cl3F3N4SPurity:99.97%Color and Shape:SolidMolecular weight:573.97Ref: TM-T9465
1mg87.00€5mg178.00€10mg281.00€25mg480.00€50mg692.00€100mg973.00€500mg1,945.00€1mL*10mM (DMSO)233.00€Lenalidomide hemihydrate
CAS:Lenalidomide hemihydrate inhibits TNF-α (IC50=13nM) and binds CRBN/DDB1 complexes.Formula:C13H13N3O3H2OPurity:96.22%Color and Shape:SolidMolecular weight:268.28PD173955
CAS:PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFormula:C21H16Cl2N4OSPurity:98.52% - 98.99%Color and Shape:SolidMolecular weight:443.35Ref: TM-T3063
2mg35.00€5mg50.00€10mg92.00€25mg166.00€50mg248.00€100mg371.00€200mg530.00€1mL*10mM (DMSO)94.00€RGX-202
CAS:RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.Formula:C4H9N3O2Purity:99.67% - 99.8%Color and Shape:SolidMolecular weight:131.13Chlorfenapyr
CAS:Chlorfenapyr (AC 303630) is a pyrrole insecticide and converts active substances (insecticidal activity) in insects by a multifunctional oxidaseFormula:C15H11BrClF3N2OPurity:99.33% - 99.49%Color and Shape:Off-White To Light Brown Powder With An Halide OdorMolecular weight:407.61Almorexant
CAS:Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.Formula:C29H31F3N2O3Purity:97.75% - 98.02%Color and Shape:SolidMolecular weight:512.56Neobavaisoflavone
CAS:Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.Formula:C20H18O4Purity:99.31% - 99.92%Color and Shape:SolidMolecular weight:322.35Ref: TM-T6S0139
5mg46.00€10mg66.00€25mg99.00€50mg144.00€100mg205.00€500mg512.00€1mL*10mM (DMSO)49.00€Sertaconazole nitrate
CAS:Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.Formula:C20H15Cl3N2OS·HNO3Purity:98.66% - 99.65%Color and Shape:SolidMolecular weight:500.78Ibandronate sodium monohydrate
CAS:Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.Formula:C9H24NNaO8P2Purity:99.62%Color and Shape:White Crystalline PowderMolecular weight:359.23Nω-Hydroxy-nor-L-Arginine Dihydrochloride
CAS:Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a competitive and reversible inhibitor of arginaseFormula:C5H14Cl2N4O3Purity:99.12% - 99.84%Color and Shape:SolidMolecular weight:249.10Ref: TM-T9096
1mg38.00€2mg50.00€5mg84.00€10mg116.00€25mg225.00€50mg335.00€100mg469.00€500mgTo inquireObatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormula:C20H19N3O·CH4O3SPurity:99.58% - 99.88%Color and Shape:SolidMolecular weight:413.49NSC622608
CAS:NSC622608, a VISTA ligand, modulates T-cell tumor attacks as an immune checkpoint.Formula:C9H12BrN3OS2Purity:98.48%Color and Shape:SolidMolecular weight:322.24Pemetrexed disodium hemipenta hydrate
CAS:Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.Formula:C20H21N5O6·2NaH2OPurity:98.76%Color and Shape:SolidMolecular weight:518.43Amifostine trihydrate
CAS:Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Formula:C5H15N2O3PS·3H2OPurity:99.71% - 99.80%Color and Shape:SolidMolecular weight:268.27CHR-6494 TFA
CAS:CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Formula:C18H17F3N6O2Purity:99.50%Color and Shape:SolidMolecular weight:406.36Ref: TM-T9521
1mg60.00€5mg122.00€10mg190.00€25mg318.00€50mg452.00€100mg627.00€200mg845.00€1mL*10mM (DMSO)142.00€Oxaprozin potassium
CAS:Oxaprozin potassium is an oral COX inhibitor (IC50: 2.2 μM for COX-1, 36 μM for COX-2), induces apoptosis, and blocks NF-κB activation.Formula:C18H14KNO3Color and Shape:SolidMolecular weight:331.412MPTP hydrochloride
CAS:MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.Formula:C12H16ClNPurity:96.35% - >99.99%Color and Shape:SolidMolecular weight:209.72Ref: TM-T4081
5mg34.00€10mg52.00€25mg80.00€50mg131.00€100mg177.00€200mg281.00€500mg447.00€1mL*10mM (DMSO)50.00€Choline
CAS:Choline is a ubiquitous water soluble nutrient, often associated with the B vitaminsFormula:C5H15NO2Purity:85% - ≥98%Color and Shape:LiquidMolecular weight:121.18Moexipril
CAS:Moexipril is an oral ACE inhibitor, lipid-soluble, targets plasma/tissue ACE, and is used for cardiovascular research.Formula:C27H34N2O7Color and Shape:SolidMolecular weight:498.57Rabeprazole sodium
CAS:Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.Formula:C18H20N3NaO3SPurity:98% - 99.912%Color and Shape:White Or Off White Crystalline PowderMolecular weight:381.42Sulforaphane
CAS:Sulforaphane is a natural isothiocyanate that activates Nrf2. Sulforaphane has antitumor and anti-inflammatory activities. Cost-effective and quality-assured.Formula:C6H11NOS2Purity:95% - 99.79%Color and Shape:Light Yellow LiquidMolecular weight:177.29BIX01294 (hydrochloride hydrate)
CAS:BIX01294 inhibits G9a HMTase (IC50=1.7μM), less effective on GLP, and aids in induced pluripotent stem cell generation.Formula:C28H43Cl3N6O3Color and Shape:SolidMolecular weight:618.04Ipatasertib
CAS:Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.Formula:C24H32ClN5O2Purity:98.28% - 99.79%Color and Shape:SolidMolecular weight:458(S)-crizotinib
CAS:(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.Formula:C21H22Cl2FN5OPurity:98.52% - 99.47%Color and Shape:SolidMolecular weight:450.34ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formula:C30H42FN5O3Purity:98.33% - 99.85%Color and Shape:SolidMolecular weight:539.68Ref: TM-TQ0029
1mg79.00€5mg137.00€10mg205.00€25mg409.00€50mg605.00€100mg860.00€1mL*10mM (DMSO)163.00€Dienogest
CAS:Dienogest (STS 557), an oral 4th-gen progestogen, is used in hormone therapy and contraception with antiandrogenic effects.Formula:C20H25NO2Purity:98% - 99.43%Color and Shape:Pale Yellow SolidMolecular weight:311.42(E/Z)-TG003
CAS:(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.Formula:C13H15NO2SPurity:98% - 99.04%Color and Shape:SolidMolecular weight:249.33Ref: TM-T1901
2mg42.00€5mg52.00€10mg92.00€25mg164.00€50mg271.00€100mg399.00€200mg567.00€1mL*10mM (DMSO)52.00€Bilobalide
CAS:Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.Formula:C15H18O8Purity:98.81% - 99.92%Color and Shape:White SolidMolecular weight:326.30Malabaricone B
CAS:Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.Formula:C21H26O4Purity:99.84% - 99.91%Color and Shape:SolidMolecular weight:342.43Cilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66AT7519
CAS:AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.Formula:C16H17Cl2N5O2Purity:98.88% - 99.65%Color and Shape:SolidMolecular weight:382.241400W dihydrochloride
CAS:1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).Formula:C10H17Cl2N3Purity:98% - 99.94%Color and Shape:SolidMolecular weight:250.17Ref: TM-T3491
5mg48.00€10mg71.00€25mg118.00€50mg207.00€100mg354.00€200mg460.00€500mg747.00€1mL*10mM (DMSO)50.00€Telekin
CAS:Telekin, a sesquiterpene lactone from Carpesium divaricatum, strongly inhibits cancer cell growth.Formula:C15H20O3Purity:99.86% - 99.97%Color and Shape:SolidMolecular weight:248.32Aloperine
CAS:Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.Formula:C15H24N2Purity:98% - 99.88%Color and Shape:Yellow Crystalline PowderMolecular weight:232.36Evocarpine
CAS:Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
Formula:C23H33NOPurity:99.77% - 99.819%Color and Shape:SolidMolecular weight:339.51Bacopaside II
CAS:Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis.Formula:C47H76O18Purity:98.14% - 99.86%Color and Shape:SolidMolecular weight:929.104-Methylsalicylic acid
CAS:4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.Formula:C8H8O3Purity:99.64%Color and Shape:Solid Solid CrystallineMolecular weight:152.15AX-024
CAS:AX-024 is an oral inhibitor of TCR-Nck with a 1 nM IC50, targeting SH3 domains, has low toxicity, is potent and selective, and reduces key cytokines.Formula:C21H22FNO2Color and Shape:SolidMolecular weight:339.4
