Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(143 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(19 products)
- Survivin(14 products)
- TNF(92 products)
- c-RET(59 products)
- p53(63 products)
Show 6 more subcategories
Found 6035 products of "Apoptosis"
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Hispidol
CAS:<p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>Formula:C15H10O4Purity:97.86% - 98.45%Color and Shape:SolidMolecular weight:254.24Quinidine
CAS:Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.Formula:C20H24N2O2Purity:97.03% - 99.99%Color and Shape:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:324.424-Methyldaphnetin
CAS:4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.Formula:C10H8O4Purity:99.73%Color and Shape:SolidMolecular weight:192.17Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purity:99.97% - >99.99%Color and Shape:SolidMolecular weight:346.42Methotrexate disodium
CAS:Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitorFormula:C20H20N8Na2O5Purity:99.77% - 99.96%Color and Shape:SolidMolecular weight:498.4Actein
CAS:Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.Formula:C37H56O11Purity:≥98%Color and Shape:Brown PowderMolecular weight:676.83UCF 101
CAS:UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.Formula:C27H17N3O5SPurity:99.64%Color and Shape:SolidMolecular weight:495.51Gomisin N
CAS:Gomisin N from Schisandra chinensis offers sedative effects, allergy relief, and cancer cell inhibition/apoptosis.Formula:C23H28O6Purity:99.97% - >99.99%Color and Shape:SolidMolecular weight:400.46PHYTOSPHINGOSINE
CAS:<p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>Formula:C18H39NO3Purity:99.81%Color and Shape:SolidMolecular weight:317.51AZD-7648
CAS:AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.Formula:C18H20N8O2Purity:99.03% - 99.85%Color and Shape:SolidMolecular weight:380.4Verbascoside
CAS:Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.Formula:C29H36O15Purity:97.46% - 99.55%Color and Shape:SolidMolecular weight:624.59CAY10404
CAS:CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.Formula:C17H12F3NO3SPurity:99.02%Color and Shape:SolidMolecular weight:367.34Picroside II
CAS:Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.Formula:C23H28O13Purity:98% - 99.83%Color and Shape:SolidMolecular weight:512.46Desmethylanethol trithione
CAS:<p>Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.</p>Formula:C9H6OS3Purity:98.05% - 98.41%Color and Shape:SolidMolecular weight:226.34ONC212
CAS:ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.Formula:C24H23F3N4OPurity:99.79%Color and Shape:SolidMolecular weight:440.46β-Ionone
CAS:<p>β-Ionone (β-lonone) is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables,with anti-proliferative, anti-metastatic</p>Formula:C13H20OPurity:98.52%Color and Shape:Colourless Liquid OilyMolecular weight:192.3GS-444217
CAS:GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).Formula:C23H21N7OPurity:99.08%Color and Shape:SolidMolecular weight:411.46PYR-41
CAS:<p>PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.</p>Formula:C17H13N3O7Purity:98.25%Color and Shape:SolidMolecular weight:371.3OUL35
CAS:OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.Formula:C14H12N2O3Purity:99.2%Color and Shape:SolidMolecular weight:256.26TCPOBOP
CAS:TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.Formula:C16H8Cl4N2O2Purity:99.7%Color and Shape:SolidMolecular weight:402.06Enzastaurin
CAS:<p>Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.</p>Formula:C32H29N5O2Purity:98% - >99.99%Color and Shape:SolidMolecular weight:515.6TREM2-IN-1
CAS:TREM2-IN-1 (OPA) is a platinum-based TREM2 inhibitor with anti-cancer and anti-tumor activity, inhibiting the immune-regulatory activity of TREM2 on macrophagesFormula:C46H68N2O20PtPurity:98.56%Color and Shape:SolidMolecular weight:1164.12EPZ004777 hydrochloride
CAS:EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.Formula:C28H42ClN7O4Color and Shape:SolidMolecular weight:576.13DB1976 dihydrochloride
CAS:DB1976 dihydrochloride (DB1976 2HCl), a transcription factor PU.1 inhibitor, has potential anti-inflammatory activity for the study of metabolic dysfunction.Formula:C20H18Cl2N8SePurity:99.08%Color and Shape:SolidMolecular weight:520.28UTL-5g
CAS:<p>UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.</p>Formula:C11H8Cl2N2O2Purity:99.83%Color and Shape:SolidMolecular weight:271.1B355252
CAS:B355252 prevents glutamate-induced cell death and boosts NGF's nerve growth effects.Formula:C25H24ClN3O3S2Purity:98.73% - 99.92%Color and Shape:SolidMolecular weight:514.06Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formula:C21H22O8Purity:98.65% - 99.76%Color and Shape:SolidMolecular weight:402.39PD173955
CAS:<p>PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and</p>Formula:C21H16Cl2N4OSPurity:98.52% - 98.99%Color and Shape:SolidMolecular weight:443.35RGX-202
CAS:RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.Formula:C4H9N3O2Purity:99.67% - 99.8%Color and Shape:SolidMolecular weight:131.13Neobavaisoflavone
CAS:Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.Formula:C20H18O4Purity:99.31% - 99.92%Color and Shape:SolidMolecular weight:322.35PD0166285
CAS:PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.Formula:C26H27Cl2N5O2Purity:99.23%Color and Shape:SolidMolecular weight:512.43Ibandronate sodium monohydrate
CAS:<p>Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.</p>Formula:C9H24NNaO8P2Purity:99.62%Color and Shape:White Crystalline PowderMolecular weight:359.23JG-98
CAS:JG-98 is an allosteric Hsp70 inhibitor, displays high active against the breast cancer cell lines MDA-MB-231 and MCF-7 (EC50s: 0.4/0.7 μM).Formula:C24H21Cl2N3OS3Purity:99.13%Color and Shape:SolidMolecular weight:534.53BI-3802
CAS:<p>BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ≤3 nM.</p>Formula:C24H29ClN6O3Purity:97.93% - 98.58%Color and Shape:SolidMolecular weight:484.98Salubrinal
CAS:<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Formula:C21H17Cl3N4OSPurity:97.25% - >99.99%Color and Shape:SolidMolecular weight:479.81Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormula:C57H92O27Purity:98.95% - ≥98%Color and Shape:SolidMolecular weight:1209.4m-3M3FBS
CAS:m-3M3FBS is a phospholipase C (PLC) activator.Formula:C16H16F3NO2SPurity:99.66%Color and Shape:SolidMolecular weight:343.36ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formula:C21H25N7Purity:97.63% - ≥95%Color and Shape:SolidMolecular weight:375.47(E/Z)-TG003
CAS:(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.Formula:C13H15NO2SPurity:98% - 99.04%Color and Shape:SolidMolecular weight:249.33Malabaricone B
CAS:Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.Formula:C21H26O4Purity:99.84% - 99.91%Color and Shape:SolidMolecular weight:342.43AT7519
CAS:AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.Formula:C16H17Cl2N5O2Purity:98.88% - 99.65%Color and Shape:SolidMolecular weight:382.24AC1NS4RE
CAS:It is a tyrosine kinase inhibitor.Formula:C15H13ClN2OPurity:99.53%Color and Shape:SolidMolecular weight:272.73Acacetin
CAS:Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidantFormula:C16H12O5Purity:96.26% - ≥95%Color and Shape:Pale-Yellow NeedlesMolecular weight:284.26VK3-OCH3
CAS:VK3-OCH3 (2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na) is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.Formula:C14H14O3SPurity:99.71%Color and Shape:SolidMolecular weight:262.32CAY10505
CAS:CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).Formula:C14H8FNO3SPurity:99.69% - 99.74%Color and Shape:SolidMolecular weight:289.28MRS 2578
CAS:MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.Formula:C20H20N6S4Purity:97.58% - 99.73%Color and Shape:White SolidMolecular weight:472.67Telekin
CAS:<p>Telekin, a sesquiterpene lactone from Carpesium divaricatum, strongly inhibits cancer cell growth.</p>Formula:C15H20O3Purity:99.86% - 99.97%Color and Shape:SolidMolecular weight:248.32Delanzomib
CAS:Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.Formula:C21H28BN3O5Purity:95.52% - 99.46%Color and Shape:SolidMolecular weight:413.28Polyphyllin I
CAS:Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Formula:C44H70O16Purity:98% - 99.5%Color and Shape:SolidMolecular weight:855.02Gardenin B
CAS:<p>Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .</p>Formula:C19H18O7Purity:98.80% - 99.74%Color and Shape:SolidMolecular weight:358.34
