Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(27 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6059 products of "Apoptosis"
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(Rac)-Idroxioleic acid
CAS:(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect.Formula:C18H34O3Purity:≥98%Color and Shape:SolidMolecular weight:298.46OsMundacetone
CAS:OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.Formula:C10H10O3Purity:99.59% - ≥95%Color and Shape:SolidMolecular weight:178.18K-Ras(G12C) inhibitor 12
CAS:K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C15H17ClIN3O3Purity:97.16%Color and Shape:SolidMolecular weight:449.67DL-Buthionine-(S,R)-sulfoximine
CAS:DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Formula:C8H18N2O3SPurity:98% - 99.64%Color and Shape:White Fine PowderMolecular weight:222.31LY-411575
CAS:<p>LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage.</p>Formula:C26H23F2N3O4Purity:97.03% - 99.38%Color and Shape:SolidMolecular weight:479.48NVP-TAE 226
CAS:NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.Formula:C23H25ClN6O3Purity:98.07% - 98.78%Color and Shape:SolidMolecular weight:468.94Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35Mycophenolate Mofetil
CAS:<p>Mycophenolate Mofetil (TM-MMF), is an immunosuppressive agent, 2-morpholinoethyl ester of MPA, and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).</p>Formula:C23H31NO7Purity:98.27% - 99.85%Color and Shape:White To Off-White Crystalline PowderMolecular weight:433.49Ospemifene
CAS:Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.Formula:C24H23ClO2Purity:99.95%Color and Shape:SolidMolecular weight:378.89Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formula:C40H57N5O7Purity:99.6% - 99.84%Color and Shape:SolidMolecular weight:719.91Sclareol
CAS:Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.Formula:C20H36O2Purity:99.58% - 99.97%Color and Shape:White Fine PowderMolecular weight:308.5TW-37
CAS:TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).Formula:C33H35NO6SPurity:97.06% - ≥95%Color and Shape:SolidMolecular weight:573.7PUMA BH3 Free base
PUMA BH3 acetate (PUMA BH3 Free base) is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd ofFormula:C130H206N42O45SPurity:96.64%Color and Shape:SolidMolecular weight:3109.35Eltrombopag
CAS:Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the plateletFormula:C25H22N4O4Purity:99.27%Color and Shape:Orange To Red SolidMolecular weight:442.47Ginkgetin
CAS:Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.Formula:C32H22O10Purity:98.63% - 99.94%Color and Shape:SolidMolecular weight:566.51Valproic Acid
CAS:Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.Formula:C8H16O2Purity:97.78% - 99%Color and Shape:Colourless To Pale Yellow Liquid ViscousMolecular weight:144.21Brassinolide
CAS:Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.Formula:C28H48O6Purity:98% - 99.189%Color and Shape:Off-White SolidMolecular weight:480.68PRLX-93936
CAS:PRLX-93936 is a selective Ras pathway protein inhibitor that modulates RAS/JNK pathway-associated protein phosphorylation, anticancer activity.Formula:C21H24N4O2Color and Shape:SolidMolecular weight:364.44PNU-74654
CAS:PNU 74654 blocks β-catenin/Tcf4, disrupting Wnt signaling (Kd = 450 nM).Formula:C19H16N2O3Purity:97.27%Color and Shape:SolidMolecular weight:320.34TCS7010
CAS:TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.Formula:C31H31ClFN7O2Purity:98.49% - 99.62%Color and Shape:SolidMolecular weight:588.07Luminespib
CAS:<p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C26H31N3O5Purity:98% - 99.25%Color and Shape:SolidMolecular weight:465.54SB 202190
CAS:SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.Formula:C20H14FN3OPurity:98% - 99.84%Color and Shape:Pale YellowMolecular weight:331.34DD1
CAS:<p>DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.</p>Formula:C16H14N2O3Purity:99.57%Color and Shape:SolidMolecular weight:282.29Rosmarinic acid
CAS:Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities.Formula:C18H16O8Purity:98.88% - 99.73%Color and Shape:Brown Fine PowderMolecular weight:360.31NSC59984
CAS:NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation.Formula:C12H15N3O4Purity:99.33% - 99.59%Color and Shape:SolidMolecular weight:265.2720(R)-Ginsenoside Rh2
CAS:20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.Formula:C36H62O8Purity:99.58%Color and Shape:SolidMolecular weight:622.87SRS11-92
CAS:SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1Formula:C22H28N2O2Purity:98.58%Color and Shape:SolidMolecular weight:352.47Millepachine
CAS:Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.Formula:C22H22O4Purity:99.73%Color and Shape:SolidMolecular weight:350.41Vanillyl Alcohol
CAS:Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant and anti-nociceptive activities.Formula:C8H10O3Purity:97.02% - 98.42%Color and Shape:Crystalline White To Off-White PowderMolecular weight:154.16Tubeimoside I
CAS:Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).Formula:C63H98O29Purity:98.89% - 99.94%Color and Shape:SolidMolecular weight:1319.43Pyrogallol
CAS:Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.Formula:C6H6O3Purity:99.88%Color and Shape:SoildMolecular weight:126.11Ixabepilone
CAS:Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor.Formula:C27H42N2O5SPurity:98% - 99.50%Color and Shape:SolidMolecular weight:506.7NVP 231
CAS:<p>NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.</p>Formula:C25H25N3O2SPurity:99.16% - ≥95%Color and Shape:SolidMolecular weight:431.55Taurolidine
CAS:Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.Formula:C7H16N4O4S2Purity:99.79% - 99.81%Color and Shape:SolidMolecular weight:284.36DC260126
CAS:DC260126 is a small-molecule antagonist of FFA1 (GPR40)Formula:C16H18FNO2SPurity:99.77%Color and Shape:SolidMolecular weight:307.38Y-27632 dihydrochloride
CAS:View and buy Y-27632 dihydrochloride from TargetMol.Y-27632 is a selective inhibitor of ROCKs.Cited in 10 publications.Formula:C14H21N3O·2HClPurity:97.96% - 99.98%Color and Shape:SolidMolecular weight:320.26Rimiducid
CAS:Rimiducid, a tacrolimus analogue, dimerizes FKBP domains to activate Caspase 9 and induce apoptosis; binds FKBP12 weakly.Formula:C78H98N4O20Purity:99.54%Color and Shape:SolidMolecular weight:1411.63Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formula:C23H22ClNO2Purity:99.25%Color and Shape:Yellowish SolidMolecular weight:379.88CCCP
CAS:CCCP blocks STING activation, TBK1, IRF3 signaling, and IFN-β production by disrupting MMP.Formula:C9H5ClN4Purity:97.15% - 99.64%Color and Shape:Yellow To Orange PowderMolecular weight:204.62NSC 15364
CAS:NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.Formula:C13H14N4OPurity:98.67%Color and Shape:SolidMolecular weight:242.28Eriocitrin
CAS:Eriocitrin: an antioxidative flavonoid; reduces exercise-induced oxidative damage and lipids; fights fatty liver and inhibits carbonic anhydrase VA.Formula:C27H32O15Purity:98.41% - 99.11%Color and Shape:SolidMolecular weight:596.53Trabectedin
CAS:Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.Formula:C39H43N3O11SPurity:≥98%Color and Shape:SolidMolecular weight:761.84Mirodenafil dihydrochloride
CAS:Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.Formula:C26H39Cl2N5O5SPurity:99.64% - 99.78%Color and Shape:SolidMolecular weight:604.59Staurosporine
CAS:Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFormula:C28H26N4O3Purity:99.24% - 99.82%Color and Shape:Off-White PowderMolecular weight:466.53Deoxypodophyllotoxin
CAS:Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.Formula:C22H22O7Purity:99.65% - 99.84%Color and Shape:SolidMolecular weight:398.41Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formula:C19H23NO4Purity:99.02% - 99.73%Color and Shape:White PowderMolecular weight:329.39Tacedinaline
CAS:Tacedinaline (CI994) is a selective class I HDAC inhibitor with potential antineoplastic activity.Formula:C15H15N3O2Purity:96.83% - 99.15%Color and Shape:WhiteMolecular weight:269.33-O-Methylgallic acid
CAS:3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins andFormula:C8H8O5Purity:99.56%Color and Shape:SolidMolecular weight:184.15W-7 hydrochloride
CAS:W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochlorideFormula:C16H22Cl2N2O2SPurity:99.63%Color and Shape:White Crystalline SolidMolecular weight:377.32ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formula:C32H22O10Purity:98% - 99.75%Color and Shape:SolidMolecular weight:566.51
