Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6064 products of "Apoptosis"
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ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formula:C23H22Cl2N2O3SPurity:98.42% - 99.55%Color and Shape:SolidMolecular weight:477.4Ref: TM-T8970
1mg46.00€5mg89.00€10mg116.00€25mg227.00€50mg354.00€100mg494.00€200mg708.00€1mL*10mM (DMSO)96.00€Poziotinib
CAS:Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).Formula:C23H21Cl2FN4O3Purity:98.69% - 99.78%Color and Shape:SolidMolecular weight:491.34Kumatakenin
CAS:Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.Formula:C17H14O6Purity:97.44% - 98.41%Color and Shape:SolidMolecular weight:314.29BG45
CAS:BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3/1/2/6 in cell-free assays, respectively.Formula:C11H10N4OPurity:99.77%Color and Shape:SolidMolecular weight:214.22BRD3308
CAS:BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.Formula:C15H14FN3O2Purity:97%Color and Shape:SolidMolecular weight:287.29Ref: TM-T8233
2mg44.00€5mg65.00€10mg97.00€25mg188.00€50mg311.00€100mg487.00€200mg692.00€1mL*10mM (DMSO)70.00€Thapsigargin
CAS:Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer.Formula:C34H50O12Purity:99.07% - 99.3%Color and Shape:Colourless FilmMolecular weight:650.75PS-1145
CAS:PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.Formula:C17H11ClN4OPurity:98.81% - >99.99%Color and Shape:SolidMolecular weight:322.75Ref: TM-T3094
1mg42.00€2mg56.00€5mg92.00€10mg127.00€25mg259.00€50mg416.00€100mg655.00€200mg924.00€1mL*10mM (DMSO)92.00€LASSBio-1135
CAS:LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.Formula:C18H14N4Purity:99.09%Color and Shape:SolidMolecular weight:286.33Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purity:98.75% - 99.57%Color and Shape:SolidMolecular weight:199.25Ref: TM-T4414
5mg73.00€10mg105.00€25mg207.00€50mg368.00€100mg652.00€500mg1,320.00€1mL*10mM (DMSO)81.00€Helichrysetin
CAS:Helichrysetin shows mild anti-HIV-1 activity and potential as an anticancer agent with cytotoxic effects on A549, MCF-7, Ca Ski, HT-29 cells.Formula:C16H14O5Purity:96.32% - ≥95%Color and Shape:SolidMolecular weight:286.28Ligustrazine
CAS:<p>Ligustrazine (Tetramethylpyrazine), a natural compound isolated from Chuan Xiong shows anti-inflammation, antioxidant, antiplatelet, and antiapoptosis effects.</p>Formula:C8H12N2Purity:99.91% - >99.99%Color and Shape:White Crystals Or PowderMolecular weight:136.19Tandutinib
CAS:Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formula:C31H42N6O4Purity:99.45% - ≥98%Color and Shape:White SolidMolecular weight:562.7Navtemadlin
CAS:Navtemadlin (AMG232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM).Cost-effective and quality-assured.Formula:C28H35Cl2NO5SPurity:95.55% - 99.08%Color and Shape:SolidMolecular weight:568.55Paederosidic acid
CAS:Paederosidic acid shows anti-tumor, anticonvulsant, and sedative properties, may treat epilepsy by modulating brain GABA and glutamate levels.Formula:C18H24O12SPurity:98% - 99.56%Color and Shape:SolidMolecular weight:464.445'-Methylthioadenosine
CAS:5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.Formula:C11H15N5O3SPurity:99.32% - 99.34%Color and Shape:SolidMolecular weight:297.33OsMundacetone
CAS:OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.Formula:C10H10O3Purity:99.59% - ≥95%Color and Shape:SolidMolecular weight:178.18DL-Buthionine-(S,R)-sulfoximine
CAS:DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Formula:C8H18N2O3SPurity:98% - 99.64%Color and Shape:White Fine PowderMolecular weight:222.31NVP-TAE 226
CAS:NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.Formula:C23H25ClN6O3Purity:98.07% - 98.78%Color and Shape:SolidMolecular weight:468.94Ref: TM-T1918
1mg48.00€2mg63.00€5mg101.00€10mg163.00€25mg264.00€50mg378.00€100mg567.00€1mL*10mM (DMSO)101.00€Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formula:C40H57N5O7Purity:99.6% - 99.84%Color and Shape:SolidMolecular weight:719.91TW-37
CAS:TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).Formula:C33H35NO6SPurity:97.06% - ≥95%Color and Shape:SolidMolecular weight:573.7Ref: TM-T6281
1mg40.00€2mg52.00€5mg69.00€10mg113.00€25mg213.00€50mg354.00€100mg522.00€1mL*10mM (DMSO)96.00€Eltrombopag
CAS:Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the plateletFormula:C25H22N4O4Purity:99.27%Color and Shape:Orange To Red SolidMolecular weight:442.47Valproic Acid
CAS:Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.Formula:C8H16O2Purity:97.78% - 99%Color and Shape:Colourless To Pale Yellow Liquid ViscousMolecular weight:144.21Brassinolide
CAS:Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.Formula:C28H48O6Purity:98% - 99.189%Color and Shape:Off-White SolidMolecular weight:480.68SB 202190
CAS:SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.Formula:C20H14FN3OPurity:98% - 99.84%Color and Shape:Pale YellowMolecular weight:331.34DD1
CAS:<p>DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.</p>Formula:C16H14N2O3Purity:99.57%Color and Shape:SolidMolecular weight:282.29SRS11-92
CAS:SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1Formula:C22H28N2O2Purity:98.58%Color and Shape:SolidMolecular weight:352.47Ref: TM-T8922
1mg46.00€5mg80.00€10mg116.00€25mg227.00€50mg359.00€100mg550.00€500mg1,159.00€1mL*10mM (DMSO)105.00€Tubeimoside I
CAS:Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).Formula:C63H98O29Purity:98.89% - 99.94%Color and Shape:SolidMolecular weight:1319.43Ref: TM-T2715
5mg35.00€10mg44.00€25mg62.00€50mg86.00€100mg111.00€200mg160.00€500mg259.00€1mL*10mM (DMSO)55.00€Pyrogallol
CAS:Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.Formula:C6H6O3Purity:99.88%Color and Shape:SoildMolecular weight:126.11Ixabepilone
CAS:Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor.Formula:C27H42N2O5SPurity:98% - 99.50%Color and Shape:SolidMolecular weight:506.7Ref: TM-T6864
1mg57.00€2mg93.00€5mg188.00€10mg344.00€25mg560.00€50mg815.00€100mg1,093.00€200mg1,473.00€1mL*10mM (DMSO)217.00€Taurolidine
CAS:Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.Formula:C7H16N4O4S2Purity:99.79% - 99.81%Color and Shape:SolidMolecular weight:284.36Y-27632 dihydrochloride
CAS:View and buy Y-27632 dihydrochloride from TargetMol.Y-27632 is a selective inhibitor of ROCKs.Cited in 10 publications.Formula:C14H21N3O·2HClPurity:97.96% - 99.98%Color and Shape:SolidMolecular weight:320.26Rimiducid
CAS:Rimiducid, a tacrolimus analogue, dimerizes FKBP domains to activate Caspase 9 and induce apoptosis; binds FKBP12 weakly.Formula:C78H98N4O20Purity:99.54%Color and Shape:SolidMolecular weight:1411.63Ref: TM-T14298
1mg136.00€2mg187.00€5mg301.00€10mg444.00€25mg730.00€50mg1,026.00€100mg1,378.00€500mg2,745.00€Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formula:C23H22ClNO2Purity:99.25%Color and Shape:Yellowish SolidMolecular weight:379.88Ref: TM-T6568
5mg47.00€10mg70.00€25mg126.00€50mg187.00€100mg279.00€200mg415.00€500mg658.00€1mL*10mM (DMSO)50.00€NSC 15364
CAS:NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.Formula:C13H14N4OPurity:98.67%Color and Shape:SolidMolecular weight:242.28Trabectedin
CAS:Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.Formula:C39H43N3O11SPurity:≥98%Color and Shape:SolidMolecular weight:761.84Mirodenafil dihydrochloride
CAS:Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.Formula:C26H39Cl2N5O5SPurity:99.64% - 99.78%Color and Shape:SolidMolecular weight:604.59Staurosporine
CAS:Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFormula:C28H26N4O3Purity:99.24% - 99.82%Color and Shape:Off-White PowderMolecular weight:466.53Ref: TM-T6680
1mg62.00€2mg87.00€5mg97.00€10mg145.00€25mg246.00€50mg401.00€100mg597.00€500mg1,283.00€1mL*10mM (DMSO)109.00€Deoxypodophyllotoxin
CAS:Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.Formula:C22H22O7Purity:99.65% - 99.84%Color and Shape:SolidMolecular weight:398.41ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formula:C32H22O10Purity:98% - 99.75%Color and Shape:SolidMolecular weight:566.51Clobenpropit dihydrobromide
CAS:Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)Formula:C14H19Br2ClN4SPurity:99.86%Color and Shape:SolidMolecular weight:470.7SCR130
CAS:SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。Formula:C19H13Cl2N3O2SPurity:98.9%Color and Shape:SolidMolecular weight:418.3Otenaproxesul
CAS:Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.Formula:C21H19NO3SPurity:98.76% - 99.13%Color and Shape:SolidMolecular weight:365.45Ref: TM-T1867
2mg40.00€5mg60.00€10mg87.00€25mg170.00€50mg274.00€100mg439.00€500mg938.00€1mL*10mM (DMSO)66.00€iCRT3
CAS:iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.Formula:C23H26N2O2SPurity:98.32% - 98.47%Color and Shape:SolidMolecular weight:394.53Alvespimycin hydrochloride
CAS:Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.Formula:C32H48N4O8·HClPurity:99.94%Color and Shape:SolidMolecular weight:653.21Torin 2
CAS:Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.Formula:C24H15F3N4OPurity:98.31% - 99.32%Color and Shape:SolidMolecular weight:432.4HJC0152 hydrochloride
CAS:HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.Formula:C15H14Cl3N3O4Purity:99.01% - 99.06%Color and Shape:SolidMolecular weight:406.64IITZ-01
CAS:IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)Formula:C26H23FN8OPurity:99.31%Color and Shape:SolidMolecular weight:482.51TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Formula:C21H17ClN2O6Purity:97.62% - 99.09%Color and Shape:SolidMolecular weight:428.82Solamargine
CAS:Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.Formula:C45H73NO15Purity:99.17% - 99.96%Color and Shape:SolidMolecular weight:868.06Ref: TM-T4034
1mg59.00€2mg82.00€5mg115.00€10mg168.00€25mg305.00€50mg459.00€100mg692.00€200mg933.00€1mL*10mM (DMSO)166.00€Demethylzeylasteral
CAS:<p>Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities.</p>Formula:C29H36O6Purity:98.74% - 99.82%Color and Shape:SolidMolecular weight:480.59
