Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(116 products)
- CDK(547 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(46 products)
- Dynamin(27 products)
- Ferroptosis(233 products)
- HSP(180 products)
- Integrin(276 products)
- Kinesin(87 products)
- LIM Kinase(21 products)
- Microtubule Associated(273 products)
- PKC(128 products)
- PLK(25 products)
- ROCK(61 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(77 products)
Show 10 more subcategories
Found 3934 products of "Cell Cycle/Checkpoint"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
CKI-7
CAS:CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formula:C11H14Cl3N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:358.67Ref: TM-T19913
1mg73.00€5mg128.00€1mL*10mM (DMSO)140.00€10mg185.00€25mg299.00€50mg405.00€100mg545.00€6-Chloropurine riboside
CAS:6-Chloropurine riboside (6-CPR): purine analog with antitumor, anti-inflammatory, antiviral, antifungal effects, and neuroprotective properties.Formula:C10H11ClN4O4Purity:96.84%Color and Shape:SoildMolecular weight:286.6700Seliciclib
CAS:Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.Formula:C19H26N6OPurity:97.15% - 99.89%Color and Shape:White To Off-White SolidMolecular weight:354.45AZ3146
CAS:AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.Formula:C24H32N6O3Purity:97.84% - >99.99%Color and Shape:SolidMolecular weight:452.55InhA-IN-2
CAS:N-[3-(Aminomethyl)phenyl]-5-chloro-3-methyl-benzo[b]thiophene-2-sulfonamide inhibits InhA without KatG activation.Formula:C16H15ClN2O2S2Purity:98.4%Color and Shape:SolidMolecular weight:366.89Ref: TM-T9734
1mg93.00€5mg182.00€1mL*10mM (DMSO)187.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,071.00€GNE-6776
CAS:GNE-6776 is a selective USP7 inhibitor.Formula:C20H20N4O2Purity:96.59% - 98.2%Color and Shape:SolidMolecular weight:348.4Zoliflodacin
CAS:Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.Formula:C22H22FN5O7Purity:99.82% - 99.93%Color and Shape:SolidMolecular weight:487.44Ref: TM-TQ0063
1mg105.00€5mg245.00€1mL*10mM (DMSO)264.00€10mg389.00€25mg645.00€50mg888.00€100mg1,234.00€500mg2,457.00€360A
CAS:360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
Formula:C27H23N5O2Purity:98.68%Color and Shape:SolidMolecular weight:449.5TH5487
CAS:TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)Formula:C19H18BrIN4O2Purity:98.38% - 98.73%Color and Shape:SolidMolecular weight:541.18TAK-960 dihydrochloride
TAK-960 dihydrochloride: oral PLK1 inhibitor, IC50 0.8 nM; also Hinders PLK2 and PLK3 (IC50s 16.9/50.2 nM); curbs cancer cell growth.Formula:C27H36Cl2F3N7O3Color and Shape:SolidMolecular weight:634.52Mogroside I E1
CAS:Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.Formula:C36H62O9Purity:98.62% - 99.71%Color and Shape:SolidMolecular weight:638.87Camostat mesylate
CAS:Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.Formula:C21H26N4O8SPurity:99.31% - 99.85%Color and Shape:Crystalline SolidMolecular weight:494.52Ref: TM-T2391
10mg48.00€1mL*10mM (DMSO)50.00€25mg69.00€50mg93.00€100mg116.00€200mg172.00€500mg281.00€CC-671
CAS:CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.Formula:C28H28N6O4Purity:98.66% - 98.8%Color and Shape:SolidMolecular weight:512.56Ref: TM-T4482
1mg50.00€5mg105.00€1mL*10mM (DMSO)120.00€10mg170.00€25mg340.00€50mg512.00€100mg733.00€500mg1,513.00€Protein kinase inhibitor 6
CAS:Protein kinase inhibitor 6 is a protein kinase inhibitor.Formula:C13H9FN2SPurity:98.01%Color and Shape:SolidMolecular weight:244.29Ref: TM-T9779
2mg34.00€5mg52.00€1mL*10mM (DMSO)52.00€10mg86.00€25mg163.00€50mg222.00€100mg324.00€200mg440.00€Dasabuvir sodium
CAS:Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).Formula:C26H26N3NaO5SColor and Shape:SolidMolecular weight:515.56Peldesine dihydrochloride
CAS:Peldesine (BCX 34) dihydrochloride is an inhibitor of PNP in humans, rats, and mice, also hindering T-cell proliferation, used in lymphoma and HIV research.Formula:C12H13Cl2N5OColor and Shape:SolidMolecular weight:314.17Abemaciclib
CAS:Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.Formula:C27H32F2N8Purity:99.43% - 99.87%Color and Shape:SolidMolecular weight:506.59Dalpiciclib hydrochloride
Dalpiciclib (SHR-6390) HCl is an oral CDK4/6 inhibitor with IC50s of 12.4/9.9 nM, an antitumor for breast and esophageal cancers.Formula:C25H31ClN6O2Color and Shape:SolidMolecular weight:483.01MLN0905
CAS:MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).Formula:C24H25F3N6SPurity:98% - 99.92%Color and Shape:SolidMolecular weight:486.56SJB2-043
CAS:SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).Formula:C17H9NO3Purity:98.44%Color and Shape:SolidMolecular weight:275.26AZD-5438
CAS:AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).Formula:C18H21N5O2SPurity:99.73% - 99.87%Color and Shape:SolidMolecular weight:371.46Pyridostatin hydrochloride
CAS:Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.Formula:C31H37Cl5N8O5Color and Shape:SolidMolecular weight:778.94NY2267
CAS:NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFormula:C38H43N3O6Purity:99.16% - 99.27%Color and Shape:SolidMolecular weight:637.76GSK2850163 hydrochloride
CAS:GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.Formula:C24H30Cl3N3OColor and Shape:SolidMolecular weight:482.87NSC23005 Sodium
CAS:NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.Formula:C13H16NNaO4SPurity:99.64%Color and Shape:SolidMolecular weight:305.32RAD51-IN-1
CAS:Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.Formula:C22H16ClN3OPurity:99.95%Color and Shape:SolidMolecular weight:373.83LDN-192960
CAS:LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).Formula:C18H20N2O2SPurity:99.01% - 99.51%Color and Shape:SolidMolecular weight:328.43Ref: TM-TQ0111
1mg49.00€2mg64.00€5mg92.00€1mL*10mM (DMSO)104.00€10mg152.00€25mg295.00€50mg477.00€100mg763.00€200mg1,018.00€L189
CAS:L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).Formula:C11H10N4OSPurity:97.37%Color and Shape:SolidMolecular weight:246.29CeMMEC13
CAS:CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).Formula:C19H16N2O4Purity:98.52%Color and Shape:SolidMolecular weight:336.34Ref: TM-T6801
1mg34.00€2mg44.00€5mg66.00€1mL*10mM (DMSO)73.00€10mg105.00€25mg230.00€50mg334.00€100mg447.00€PF-06873600
CAS:PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.Formula:C20H27F2N5O4SPurity:98.77% - 99.55%Color and Shape:SolidMolecular weight:471.52Ref: TM-T8463
1mg54.00€5mg114.00€1mL*10mM (DMSO)118.00€10mg178.00€25mg334.00€50mg557.00€100mg888.00€200mg1,198.00€2'-Deoxy-2'-fluorocytidine
CAS:2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.Formula:C9H12FN3O4Purity:99.90%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:245.21BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Formula:C22H32N6·HClPurity:99.21%Color and Shape:SolidMolecular weight:416.99Ref: TM-T6162
200mgTo inquire1mg37.00€2mg52.00€5mg79.00€1mL*10mM (DMSO)87.00€10mg116.00€25mg250.00€50mg416.00€100mg645.00€Talotrexin
CAS:Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.Formula:C27H27N9O6Color and Shape:SolidMolecular weight:573.56DMT-2′Fluoro-dU Phosphoramidite
CAS:DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.Formula:C39H46FN4O8PPurity:99.5%Color and Shape:SolidMolecular weight:748.78Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Formula:C5H7N6NaO5SPurity:99.55%Color and Shape:SolidMolecular weight:286.2GLPG0187
CAS:GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Formula:C29H37N7O5SPurity:99.4% - 99.70%Color and Shape:SolidMolecular weight:595.71Ref: TM-T4259
1mg44.00€5mg98.00€1mL*10mM (DMSO)129.00€10mg144.00€25mg236.00€50mg350.00€100mg522.00€500mg1,134.00€Roniciclib
CAS:Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.Formula:C18H21F3N4O3SPurity:98% - 98.63%Color and Shape:SolidMolecular weight:430.44SC-514
CAS:SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.Formula:C9H8N2OS2Purity:99.88% - >99.99%Color and Shape:SolidMolecular weight:224.3Danofloxacin
CAS:Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.Formula:C19H20FN3O3Purity:99.77% - 99.8%Color and Shape:SolidMolecular weight:357.38Protein kinase inhibitors 1
CAS:Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.Formula:C18H17N5O3SPurity:98%Color and Shape:SolidMolecular weight:383.42Emvistegrast
CAS:Emvistegrast is a quinolone derivative that acts as an antagonist for the α4β7 integrin.Formula:C35H32F4N6O6Color and Shape:SolidMolecular weight:708.66LY3143921
CAS:LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].Formula:C16H12FN5OColor and Shape:SolidMolecular weight:309.3NSC 617145
CAS:NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFormula:C13H10Cl4N2O4Purity:99.78%Color and Shape:SolidMolecular weight:400.04Ref: TM-T9168
1mg34.00€2mg49.00€5mg73.00€1mL*10mM (DMSO)80.00€10mg90.00€25mg164.00€50mg227.00€100mg358.00€500mg842.00€ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formula:C21H25N7Purity:97.63% - ≥95%Color and Shape:SolidMolecular weight:375.47FEN1-IN-SC13
CAS:FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)
Formula:C24H23N3O3SPurity:98.02%Color and Shape:SolidMolecular weight:433.52Dasabuvir
CAS:Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.Formula:C26H27N3O5SPurity:99.54% - 99.62%Color and Shape:SolidMolecular weight:493.57IRE1α kinase-IN-1
CAS:IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM.Formula:C26H26ClFN8Purity:99.18%Color and Shape:SolidMolecular weight:504.99Ref: TM-T9564
1mg110.00€5mg268.00€1mL*10mM (DMSO)295.00€10mg427.00€25mg670.00€50mg964.00€100mg1,333.00€CBFβ Inhibitor
CAS:CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.Formula:C12H14N2OSPurity:96.50%Color and Shape:SolidMolecular weight:234.32P005091
CAS:P005091 (P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.Formula:C12H7Cl2NO3S2Purity:99.53% - 99.87%Color and Shape:SolidMolecular weight:348.22Natalizumab
CAS:Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Purity:97.15% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.00%Color and Shape:LiquidMolecular weight:146.19 kDaBSJ-4-116
CAS:BSJ-4-116: potent, selective CDK12 PROTAC, IC50 = 6 nM; downregulates DDR genes, induces premature transcription termination.Formula:C40H49ClN8O8SPurity:99.09%Color and Shape:SolidMolecular weight:837.38PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:CRT0066101 dihydrochloride is an inhibitor of PKD.Formula:C18H21Cl3N4OPurity:99.5%Color and Shape:SolidMolecular weight:415.75NG 52
CAS:NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.Formula:C16H19ClN6OPurity:98% - 99.34%Color and Shape:SolidMolecular weight:346.81SCH900776
CAS:SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.Formula:C15H18BrN7Purity:96.69% - 99.6%Color and Shape:SolidMolecular weight:376.25Eprociclovir potassium
CAS:Eprociclovir potassium, 15x stronger than acyclovir, inhibits EHV1 and human herpesviruses, also treats herpetic keratitis effectively with eyedrops.Formula:C11H15KN5O3Color and Shape:SolidMolecular weight:304.37USP7-IN-8
CAS:Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM.Formula:C21H21N3O2Purity:99.31%Color and Shape:SolidMolecular weight:347.41Ref: TM-T9217
1mg46.00€5mg92.00€1mL*10mM (DMSO)100.00€10mg147.00€25mg269.00€50mg389.00€100mg532.00€200mg705.00€JNJ-7706621
CAS:JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formula:C15H12F2N6O3SPurity:99.1% - 99.85%Color and Shape:SolidMolecular weight:394.36Ref: TM-T6126
1mg48.00€1mL*10mM (DMSO)94.00€5mg100.00€10mg155.00€25mg268.00€50mg432.00€100mg595.00€200mg833.00€Favipiravir sodium
CAS:Favipiravir sodium inhibits viral RNA polymerases, effective against flu, West Nile, yellow fever, and more RNA viruses.Formula:C5H4FN3NaO2Color and Shape:SolidMolecular weight:180.09BI-1347
CAS:BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.Formula:C22H20N4OPurity:96.7% - 99.63%Color and Shape:SolidMolecular weight:356.42Ref: TM-T5405
1mg40.00€1mL*10mM (DMSO)87.00€5mg88.00€10mg126.00€25mg240.00€50mg439.00€100mg647.00€500mg1,359.00€COH29
CAS:COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.Formula:C22H16N2O5SPurity:97.04% - 98.92%Color and Shape:SolidMolecular weight:420.44Ref: TM-T3157
1mg34.00€2mg49.00€5mg74.00€1mL*10mM (DMSO)82.00€10mg113.00€25mg178.00€50mg334.00€100mg557.00€200mg790.00€ML167
CAS:ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.Formula:C19H17N3O3Purity:99.82% - >99.99%Color and Shape:SolidMolecular weight:335.36Ref: TM-T2670
2mg33.00€5mg47.00€1mL*10mM (DMSO)50.00€10mg71.00€25mg135.00€50mg222.00€100mg331.00€200mg470.00€DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.Formula:C41H49N4O9PPurity:98.28%Color and Shape:SolidMolecular weight:772.82Belumosudil
CAS:Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).Formula:C26H24N6O2Purity:97.64% - 98.59%Color and Shape:SolidMolecular weight:452.51Ref: TM-T6867
2mg46.00€5mg70.00€1mL*10mM (DMSO)74.00€10mg95.00€25mg158.00€50mg236.00€100mg356.00€500mg848.00€5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE
CAS:5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.Formula:C8H13N3SPurity:99.03%Color and Shape:SolidMolecular weight:183.276-Bromo-2-hydroxy-3-methoxybenzaldehyde
CAS:6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α (IC50 : 0.08 μM).Formula:C8H7BrO3Purity:99.82%Color and Shape:SolidMolecular weight:231.04NITD-2
CAS:NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Formula:C23H19N3O4SPurity:98.03% - 99.46%Color and Shape:SolidMolecular weight:433.48Ref: TM-T8886
1mg74.00€5mg170.00€1mL*10mM (DMSO)188.00€10mg274.00€25mg472.00€50mg655.00€100mg944.00€200mg1,264.00€Fialuridine
CAS:Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.Formula:C9H10FIN2O5Purity:99.71% - 99.88%Color and Shape:Less Crystals Colourless CrystalsMolecular weight:372.09SEL120-34A HCl
CAS:SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectivelyFormula:C15H19Br2ClN4Purity:98.13% - 98.47%Color and Shape:SolidMolecular weight:450.6Afuresertib
CAS:Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFormula:C18H17Cl2FN4OSPurity:97.51% - 99.51%Color and Shape:SolidMolecular weight:427.32Ref: TM-T1911
1mg37.00€2mg52.00€5mg74.00€1mL*10mM (DMSO)74.00€10mg92.00€25mg166.00€50mg259.00€100mg452.00€500mg982.00€Brequinar
CAS:Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.Formula:C23H15F2NO2Purity:99.1% - 99.57%Color and Shape:SolidMolecular weight:375.37CHR-6494 TFA
CAS:CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Formula:C18H17F3N6O2Purity:99.50%Color and Shape:SolidMolecular weight:406.36Ref: TM-T9521
1mg60.00€5mg122.00€1mL*10mM (DMSO)142.00€10mg190.00€25mg318.00€50mg452.00€100mg627.00€200mg845.00€SRI-29329
CAS:SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).Formula:C20H26ClN7Purity:99.18%Color and Shape:SolidMolecular weight:399.92Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFormula:C24H26N4O5SPurity:99.00% - 99.86%Color and Shape:SolidMolecular weight:482.55Ref: TM-T4226
1mg34.00€1mL*10mM (DMSO)52.00€5mg71.00€10mg92.00€25mg152.00€50mg222.00€100mg334.00€200mg494.00€Temozolomide Acid
CAS:TMZA, a TMZ metabolite, shows in vitro anticancer effects. TMZ, an oral alkylator, treats GBM and astrocytomas.Formula:C6H5N5O3Purity:99.28%Color and Shape:SolidMolecular weight:195.14GSK269962A
CAS:GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.Formula:C29H30N8O5Purity:99.14% - 99.71%Color and Shape:SolidMolecular weight:570.6XL177A
CAS:XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.Formula:C48H57ClN8O5Purity:98.75%Color and Shape:SolidMolecular weight:861.47NSC23005
CAS:NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).Formula:C13H17NO4SPurity:>99.99%Color and Shape:SolidMolecular weight:283.34Dalpiciclib
CAS:Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.
Formula:C25H30N6O2Purity:99.69%Color and Shape:SolidMolecular weight:446.54DUB-IN-1
CAS:DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific protease (USPs).Formula:C20H11N5OPurity:98.33% - 98.96%Color and Shape:SolidMolecular weight:337.33Ref: TM-T11110
1mg62.00€5mg110.00€1mL*10mM (DMSO)122.00€10mg173.00€25mg334.00€50mg469.00€100mg618.00€200mg848.00€CYC-116
CAS:CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormula:C18H20N6OSPurity:97.36% - 97.59%Color and Shape:SolidMolecular weight:368.46Acelarin
CAS:Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.Formula:C25H27F2N4O8PPurity:99.26%Color and Shape:SolidMolecular weight:580.47Ref: TM-T4060
200mgTo inquire1mg43.00€2mg56.00€1mL*10mM (DMSO)92.00€5mg93.00€10mg137.00€25mg259.00€50mg398.00€100mg555.00€CDK9-IN-30
CAS:CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.Formula:C16H20FNO3Purity:99.75%Color and Shape:SolidMolecular weight:293.33Empesertib
CAS:Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Formula:C29H26FN5O4SPurity:97.45% - 99.4%Color and Shape:SolidMolecular weight:559.61POL1-IN-1
CAS:POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂，IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。
Formula:C21H20N6Purity:98% - 98.01%Color and Shape:SolidMolecular weight:356.42Rifamycin sodium
CAS:Rifamycin sodium (Rifamycin sodium salt) salt is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase.Formula:C37H46NNaO12Purity:97.72%Color and Shape:CoaMolecular weight:719.75MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46Ref: TM-T22106
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg86.00€25mg161.00€50mg245.00€100mg363.00€200mg515.00€IU1-248
CAS:IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM[1].Formula:C20H23N3O2Purity:99.3%Color and Shape:SolidMolecular weight:337.42Ref: TM-T9375
1mg48.00€5mg92.00€1mL*10mM (DMSO)102.00€10mg152.00€25mg301.00€50mg424.00€100mg605.00€200mg845.00€K858 (Racemic)
CAS:K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formula:C13H15N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:277.34Lifitegrast
CAS:Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
Formula:C29H24Cl2N2O7SPurity:99.39% - 99.66%Color and Shape:SolidMolecular weight:615.48Mitonafide
CAS:Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.Formula:C16H15N3O4Purity:99.89%Color and Shape:SolidMolecular weight:313.31Ref: TM-T25817
1mg34.00€2mg46.00€5mg66.00€1mL*10mM (DMSO)73.00€10mg90.00€25mg178.00€50mg295.00€100mg484.00€200mg690.00€500mg1,035.00€LXW7
CAS:LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Formula:C29H48N12O12S2Purity:>99.99%Color and Shape:SolidMolecular weight:820.891,4-Anthraquinone
CAS:1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.Formula:C14H8O2Purity:95.96% - 97.01%Color and Shape:Orange Brown SolidMolecular weight:208.21MC180295
CAS:MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.Formula:C17H18N4O3SPurity:99.84%Color and Shape:SolidMolecular weight:358.41Ref: TM-T5533
1mg52.00€5mg124.00€1mL*10mM (DMSO)136.00€10mg177.00€25mg301.00€50mg424.00€100mg605.00€200mg797.00€2',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS:2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication，AIDS and herpes.Formula:C21H40N2O6Si2Purity:99.88%Color and Shape:SolidMolecular weight:472.723'-Deoxy-3'-fluoroadenosine
CAS:3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borneFormula:C10H12FN5O3Purity:99.84%Color and Shape:SolidMolecular weight:269.23PDD00017273
CAS:PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.Formula:C23H26N6O4S2Purity:99.14% - 99.21%Color and Shape:SolidMolecular weight:514.62Ref: TM-T5700
5mg78.00€1mL*10mM (DMSO)92.00€10mg130.00€25mg269.00€50mg403.00€100mg580.00€500mg1,198.00€2'-C-β-Methylguanosine
CAS:2'-C-beta-Methylguanosine (2'-C-Methylguanosine), with antiviral activity, inhibits dengue virus 2.Formula:C11H15N5O5Purity:99.37%Color and Shape:SolidMolecular weight:297.275-Bromouridine
CAS:5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.Formula:C9H11BrN2O6Purity:99.89%Color and Shape:White PowderMolecular weight:323.1P-2'-deoxyribose
CAS:P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms.Formula:C11H15N3O5Purity:99.71%Color and Shape:SolidMolecular weight:269.25Ref: TM-TNU1281
1mg109.00€2mg160.00€5mg261.00€10mg374.00€25mg583.00€50mg803.00€100mg1,063.00€200mg1,431.00€Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Formula:C27H36N6O3Purity:99.53%Color and Shape:SolidMolecular weight:492.61
![5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT8912.webp&w=3840&q=75)
