Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3035 products of "Immunology and Inflammation"
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DDO-7263
CAS:<p>DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory effects.</p>Formula:C14H9F2N3OPurity:99.85%Color and Shape:SolidMolecular weight:273.24Keap1-Nrf2-IN-16
CAS:<p>Keap1-Nrf2-IN-16 is a biologically active peptide with KEAP1 binding activity.</p>Formula:C73H114N16O26Color and Shape:SolidMolecular weight:1631.78AMPCP
CAS:<p>AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor.</p>Formula:C11H15N5Na2O9P2Color and Shape:SolidMolecular weight:469.194-CPPC
CAS:<p>4-CPPC inhibits MIF-2 (IC50=27μM), not MIF-1; blocks MIF-2/CD74 binding and MIF-2-induced ERK1/2 in fibroblasts.</p>Formula:C14H9NO6Purity:97.50% - 98.03%Color and Shape:SolidMolecular weight:287.22Fenquinotrione
CAS:<p>Fenquinotrione, a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, exhibits IC50 values of 27.2 and 44.7 nM against HPPD from rice and Arabidopsis thaliana</p>Formula:C22H17ClN2O5Color and Shape:SolidMolecular weight:424.83TLR8 agonist 5
CAS:<p>TLR8 Agonist 5, exhibiting potent efficacy as a TLR8 agonist, demonstrates an EC50 of 20 nM in HEK-Blue hTLR8, effectively activating the immune response.</p>Formula:C31H40N6O5Color and Shape:SolidMolecular weight:576.69PK68
CAS:<p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>Formula:C22H24N4O3SPurity:98.09% - 99.64%Color and Shape:SolidMolecular weight:424.52ML-090
CAS:<p>ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).</p>Formula:C14H10N4Purity:98.55%Color and Shape:SolidMolecular weight:234.26Glabrescone C
CAS:<p>Glabrescone C exhibits strong anti-inflammatory properties through direct binding to IKKα/β.</p>Formula:C19H22O7Color and Shape:SolidMolecular weight:362.37TLR7/8 agonist 8
CAS:<p>TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of</p>Formula:C24H30N6OColor and Shape:SolidMolecular weight:418.53PF 184
CAS:<p>IKKβ inhibitor</p>Formula:C32H32ClFN6O4Purity:98%Color and Shape:SolidMolecular weight:619.09NLRP3-IN-9
CAS:<p>NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.</p>Formula:C12H13ClO3Purity:99.64%Color and Shape:SolidMolecular weight:240.68IKK-IN-4
CAS:<p>IKK-IN-4 is a potent and selective inhibitor of IkappaB kinase 2 with IC 50 values of 45 and 650 nM against IKKβ and IKKα, respectively [1].</p>Formula:C18H19N5SColor and Shape:SolidMolecular weight:337.44DNA polymerase-IN-1
CAS:<p>DNA polymerase-IN-1 exhibits antiproliferative activity against tumor cells and inhibits Taq DNA polymerase as a DNA polymerase inhibitor.</p>Formula:C10H7ClO4Purity:99.16%Color and Shape:SolidMolecular weight:226.61TLR7 agonist 23
CAS:<p>TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.</p>Formula:C21H22N4O2Color and Shape:SolidMolecular weight:362.42Arginase inhibitor 1
CAS:<p>Arginase inhibitor 1 is a potent inhibitor of human arginases I and II (IC50s: 223 and 509 nM).</p>Formula:C13H27BN2O4Color and Shape:SolidMolecular weight:286.18(R)-IL-17 modulator 4
CAS:<p>(R)-IL-17 modulator 4, an R-isomer prodrug of IL-17 modulator 1, is potent and taken orally.</p>Formula:C27H34N6O2Color and Shape:SolidMolecular weight:474.6Factor B-IN-2
CAS:<p>Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.</p>Formula:C25H32N2O4Color and Shape:SolidMolecular weight:424.53STING-IN-5
CAS:<p>STING-IN-5 suppresses NO synthesis in macrophages, inhibits STING pathway with IC50 of 1.15 μM, and may aid anti-inflammatory and sepsis research.</p>Formula:C47H67NO9S2Purity:98%Color and Shape:SolidMolecular weight:854.17Anti-inflammatory agent 46
CAS:<p>Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energies</p>Formula:C24H19FN2O3SPurity:98%Color and Shape:SolidMolecular weight:434.48RIP1 kinase inhibitor 4
CAS:<p>RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].</p>Formula:C23H23N5Purity:98%Color and Shape:SolidMolecular weight:369.46TLR4 agonist-1
CAS:<p>TLR4 agonist-1 (compound 17a) serves as a potent activator of Toll-like Receptor 4 (TLR4) and stimulates the production of MIP-1β in RAW 264.7 and MM6 cells [1</p>Formula:C81H158N3O15PColor and Shape:SolidMolecular weight:1445.11hnNOS-IN-2
CAS:<p>Compound 17, also known as hnNOS-IN-2, is an inhibitor of human neuronal nitric oxide synthase (hnNOS) that exhibits good metabolic stability.</p>Formula:C18H23F2N3Purity:98%Color and Shape:SolidMolecular weight:319.39Aminoguanidine hemisulfate
CAS:<p>Aminoguanidine hemisulfate, an inhibitor of nitric oxide synthases (NOS) and reactive oxygen species (ROS), effectively suppresses ANE-induced ROS production in</p>Formula:CH6N4H2SO4Purity:98%Color and Shape:SolidMolecular weight:123.115IMD-biphenylC
CAS:<p>IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.</p>Formula:C35H33N5O3Purity:98%Color and Shape:SolidMolecular weight:571.67ICy-Q
CAS:<p>ICy-Q, a NIR reagent activated by NQO-1, triggers pyroptosis in pancreatic cancer cells, aiding diagnosis.</p>Formula:C48H50I2N2O5Purity:98%Color and Shape:SolidMolecular weight:988.73GBT1118
CAS:<p>GBT1118 is an orally active allosteric modulator of haemoglobin oxygen affinity, enhancing tolerance to acute severe hypoxia and suitable for hypoxia research.</p>Formula:C19H20N2O4Purity:99.69%Color and Shape:SolidMolecular weight:340.37TBK1-IN-1
CAS:<p>TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.</p>Formula:C27H37N7O2Purity:>99.99%Color and Shape:SolidMolecular weight:491.63Dapsone hydroxylamine
CAS:<p>Dapsone hydroxylamine (DDS-NOH) promotes methemoglobinemia, impedes catalase (CAT) activity, and suppresses the generation of reactive oxygen species, while</p>Formula:C12H12N2O3SPurity:98%Color and Shape:SolidMolecular weight:264.3NLRP3-IN-21
CAS:<p>NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties.</p>Formula:C20H13Cl2F3N6O2SPurity:98%Color and Shape:SolidMolecular weight:529.32MALT1-IN-7
CAS:<p>MALT1-IN-7 (compound 142b) is a potent inhibitor of MALT1 protease with potential for cancer research.</p>Formula:C19H17F3N8O2SColor and Shape:SolidMolecular weight:478.45IMD-vanillin
CAS:<p>IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.</p>Formula:C37H45N7O4Purity:98%Color and Shape:SolidMolecular weight:651.8IRAK4-IN-28
CAS:<p>IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme.</p>Formula:C27H31N9O3Purity:98%Color and Shape:SolidMolecular weight:529.59CCT374705
CAS:<p>CCT374705, an orally active BCL6 inhibitor, exhibits potent antiproliferative effects in vitro and effectively inhibits tumor growth in a lymphoma xenograft</p>Formula:C21H18ClF3N4O2Color and Shape:SolidMolecular weight:450.84Galectin-3 antagonist 2
CAS:<p>Galectin-3: a lectin aiding BCP-ALL cell migration & drug resistance.</p>Formula:C22H23NO10Purity:98%Color and Shape:SolidMolecular weight:461.42BF738735
CAS:<p>BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM).</p>Formula:C21H19FN4O3SPurity:90%Color and Shape:SolidMolecular weight:426.46RIPK2-IN-3
CAS:<p>RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor with anti-inflammatory and anticancer activities, useful for research on immune diseases and cancer.</p>Formula:C25H22N4O2Purity:99.57%Color and Shape:SolidMolecular weight:410.47h-NTPDase-IN-3
CAS:<p>h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8.</p>Formula:C16H10N4SPurity:98.24%Color and Shape:SolidMolecular weight:290.34NVS-MALT1
CAS:<p>NVS-MALT1 is an allosteric inhibitor of MALT1 [1].</p>Formula:C24H27ClF3N5O4SColor and Shape:SolidMolecular weight:574.02(-)-Bornyl ferulate
CAS:<p>(-)-Bornyl ferulate is a dual inhibitor of 5-lipoxygenase and cyclooxygenase (COX), exhibiting half-maximal inhibitory concentrations (IC50s) of 10.4 μM for 5-</p>Formula:C20H26O4Purity:98%Color and Shape:SolidMolecular weight:330.42Antitumor agent-114
CAS:<p>Antitumor Agent-114, a potent STING (stimulator of interferon genes) agonist, activates immune responses and diminishes tumor size in mouse breast cancer models</p>Formula:C39H50F2N10O13P2Purity:98%Color and Shape:SolidMolecular weight:966.82NF-κB-IN-13
CAS:<p>NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1</p>Formula:C20H20O5Purity:98%Color and Shape:SolidMolecular weight:340.37BI 7446
CAS:<p>BI 7446 is a potent and selective cyclic dinucleotide (CDN)-based stimulator of interferon genes (STING) agonist capable of activating all five STING variants</p>Formula:C20H22FN9O10P2S2Purity:98%Color and Shape:SolidMolecular weight:693.52CD73-IN-6
CAS:<p>CD73-IN-6, serves as a potent inhibitor of CD73. This compound finds utility in cancer research [1].</p>Formula:C20H15N7O2Color and Shape:SolidMolecular weight:385.38FCE-27164
CAS:<p>FCE-27164 inhibits PDGF-β and IL-7 receptor binding, potentially modulating inflammatory and immune responses for therapeutic applications.</p>Formula:C45H34N10Na6O23S6Purity:96.04%Color and Shape:SolidMolecular weight:1413.11Dexamethasone palmitate
CAS:<p>DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.</p>Formula:C38H59FO6Purity:99.28%Color and Shape:SolidMolecular weight:630.87CD73-IN-10
CAS:<p>CD73-IN-10, a potent inhibitor of CD73, aids in creating cancer drugs by hindering adenosine synthesis, which fosters tumor growth.</p>Formula:C15H13F2N5O2Color and Shape:SolidMolecular weight:333.29TLR7 agonist 14
CAS:<p>Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM.</p>Formula:C29H36N6O3Color and Shape:SolidMolecular weight:516.63BD-AcAc 2
CAS:<p>BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones.</p>Formula:C8H16O4Purity:99.62%Color and Shape:SolidMolecular weight:176.21NLRP3-IN-18
CAS:<p>NLRP3-IN-18, also known as compound 13, is a potent inhibitor of NLRP3, demonstrating an IC50 value of ≤1.0 µM [1].</p>Formula:C19H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:339.82Friluglanstat
CAS:<p>Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].</p>Formula:C25H20ClF3N4O3Purity:98%Color and Shape:SolidMolecular weight:516.9CD38 inhibitor 2
CAS:<p>CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).</p>Formula:C19H24N6O3Color and Shape:SolidMolecular weight:384.43MAPK-IN-1
CAS:<p>MAPK-IN-1 inhibits MAPK for Alzheimer's research with anti-inflammatory effects, IC50 of 23.84 μM against AChE.</p>Formula:C19H18O4Color and Shape:SolidMolecular weight:310.34NLRP3-IN-22
CAS:<p>NLRP3-IN-22 (Compound II-4) is an inhibitor of NLRP3, exhibiting a 67% inhibition rate at a concentration of 10 μM [1].</p>Formula:C19H12F3NO4SPurity:98%Color and Shape:SolidMolecular weight:407.36W-54011
CAS:<p>W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).</p>Formula:C30H37ClN2O2Purity:96.8%Color and Shape:SolidMolecular weight:493.08OATD-02
CAS:<p>OATD-02 is an orally active, competitive, reversible, noncovalent inhibitor with slow offset kinetics that targets both Arginase1 and 2, exhibiting inhibitory</p>Formula:C12H25BN2O4Purity:98%Color and Shape:SolidMolecular weight:272.15Keap1-Nrf2-IN-15
CAS:<p>Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence</p>Formula:C39H35N3O12S2Color and Shape:SolidMolecular weight:801.845J-4
CAS:<p>5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE).</p>Formula:C16H12N2O3SPurity:96.12%Color and Shape:SolidMolecular weight:312.34JT002
CAS:<p>JT002 is an orally active NLRP3 inflammasome inhibitor that decreases the production of NLRP3-dependent proinflammatory cytokines (such as IL-1β, IL-1α, IL-18)</p>Formula:C20H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:432.49Nitric oxide production-IN-1
CAS:<p>Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis.</p>Formula:C33H52O15Purity:98%Color and Shape:SolidMolecular weight:688.76TMV-IN-2
CAS:<p>TMV-IN-2, a chalcone, inhibits TMV with an EC50 of 89.9 μg/mL, used in infection and tumor studies.</p>Formula:C27H23FO4Color and Shape:SolidMolecular weight:430.473'-Azido-3'-deoxy-5-methylcytidine
CAS:<p>3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related</p>Formula:C10H14N6O4Purity:99.55%Color and Shape:SolidMolecular weight:282.26Ro26-4550
CAS:<p>Ro26-4550 is a competitive reversible inhibitor of interleukin-2 (IL-2) binding to IL-2R α-subunit (IC50 = 3 μM).</p>Formula:C26H30N4O3Purity:98%Color and Shape:SolidMolecular weight:446.54Keap1-Nrf2-IN-6
<p>Keap1-Nrf2-IN-6 is a potent, selective inhibitor of the Keap1-Nrf2 protein−protein interaction (PPI), demonstrating an inhibitory concentration (IC50) of 41 nM</p>Formula:C30H34N4O8SColor and Shape:SolidMolecular weight:610.68PF-184
<p>PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.</p>Formula:C32H32ClFN6O4Color and Shape:SolidMolecular weight:619.09RPR-106541
CAS:<p>RPR-106541, a GR agonist, is used potentially for the treatment of asthma.</p>Formula:C24H34F2O4SColor and Shape:SolidMolecular weight:456.59IFN α-IFNAR-IN-1 hydrochloride
CAS:<p>IFN alpha-IFNAR-IN-1 HCl blocks IFN-α/IFNAR binding; IC50 2-8 μM in BM-pDCs' MVA-induced IFN-α response.</p>Formula:C18H18ClNSPurity:99.77%Color and Shape:SolidMolecular weight:315.86TMV-IN-4
CAS:<p>TMV-IN-4, a TMV inhibitor, enhances plant defense and TMV resilience by interacting with helicase, increasing peroxidase and SOD activity.</p>Formula:C18H21NO4Color and Shape:SolidMolecular weight:315.36CD73-IN-4
CAS:<p>CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor</p>Formula:C16H23ClN5O7PPurity:98.61%Color and Shape:SolidMolecular weight:463.81(R)-MALT1-IN-7
CAS:<p>(R)-MALT1-IN-7 (compound 142a) is a potent inhibitor of MALT1 protease and has potential for cancer research.</p>Formula:C19H17F3N8O2SColor and Shape:SolidMolecular weight:478.45Bay 65-1942 (R form)
CAS:<p>Bay 65-1942 R form is the less active R-form of Bay 65-1942. Bay 65-1942 is a selective and ATP-competitive IKKβ inhibitor.</p>Formula:C22H25N3O4Purity:98%Color and Shape:SolidMolecular weight:395.45BW 755C
CAS:<p>BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.</p>Formula:C10H10F3N3Purity:96.52%Color and Shape:SolidMolecular weight:229.2ST 2825
CAS:<p>ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 inhibition of IL-1β-mediated activation of NF-κB transcriptional activity.</p>Formula:C27H28Cl2N4O5SPurity:98%Color and Shape:SolidMolecular weight:591.51CD73-IN-11
CAS:<p>CD73-IN-11 is a potent inhibitor used to prepare medication for cancer by blocking adenosine production, which fosters tumor growth.</p>Formula:C14H10F3N5O2Color and Shape:SolidMolecular weight:337.26STING Agonist D61
CAS:<p>STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline</p>Formula:C29H29F3N8O4Color and Shape:SolidMolecular weight:610.60GSK2256294A
CAS:<p>GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.</p>Formula:C21H24F3N7OPurity:99.86% - 99.86%Color and Shape:SolidMolecular weight:447.46Glu-urea-Glu-NHS ester
CAS:<p>Compound 21, Glu-urea-Glu-NHS ester, an activated N-hydroxysuccinamide (NHS) ester derivative of Glu-urea-Glu, serves as a pharmacophore for conjugation to prostate specific membrane antigen (PSMA) inhibitors [1].</p>Formula:C27H43N3O11Color and Shape:SolidMolecular weight:585.64Trovafloxacin mesylate
CAS:<p>Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).</p>Formula:C21H19F3N4O6SPurity:99.18%Color and Shape:SolidMolecular weight:512.46Argininosuccinic acid disodium
CAS:<p>Argininosuccinic acid disodium, involved in the urea cycle's fourth step, is cleaved by argininosuccinate lyase (ASL) into arginine and fumarate.</p>Formula:C10H16N4Na2O6Purity:98%Color and Shape:SolidMolecular weight:334.24Dimethoxycurcumin
CAS:<p>Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.</p>Formula:C23H24O6Purity:99.87%Color and Shape:SolidMolecular weight:396.43MALT1-IN-9
CAS:<p>MALT1-IN-9: potent MALT1 protease inhibitor, IC50 <500 nM in Raji cells, significant anticancer effects.</p>Formula:C16H12ClF3N6OColor and Shape:SolidMolecular weight:396.75Nrf2-IN-1
CAS:<p>Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).</p>Formula:C21H22ClN3O2Purity:95.00% - 99.68%Color and Shape:SolidMolecular weight:383.87Glutathione ethyl ester
CAS:<p>Glutathione ethyl ester is a cell-permeable, modified form of glutathione (GSH) that undergoes rapid hydrolysis by esterases in vivo to restore GSH levels.</p>Formula:C12H21N3O6SPurity:98.958%Color and Shape:SoildMolecular weight:335.38Nrf2 activator-7
CAS:<p>Nrf2 Activator-7 (Compound 12b) effectively enhances the Nrf2 signaling pathway as a potent Nrf2 activator.</p>Formula:C35H32N2O11S2Color and Shape:SolidMolecular weight:720.77STING agonist-3
CAS:<p>STING agonist-3: non-nucleotide, selective, anti-tumor with pEC50=7.5, pIC50=9.5, could enhance cancer therapy.</p>Formula:C37H42N12O6Purity:98%Color and Shape:SolidMolecular weight:750.81COX-2-IN-30
CAS:<p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>Formula:C17H16N6O3SPurity:98%Color and Shape:SolidMolecular weight:384.41Thromboxane B3
CAS:<p>Thromboxane B3 (TXB3), the stable hydrolysis product of TXA3, is synthesized from eicosapentaenoic acid (EPA) through the action of COX and thromboxane synthase enzymes. This compound is biosynthesized in several tissues, including seminal vesicles, lungs, polymorphonuclear leukocytes (PMNL), and ocular tissues.</p>Formula:C20H32O6Color and Shape:SolidMolecular weight:368.5TIM-3-IN-2
CAS:<p>TIM-3-IN-2 is a Tim3 inhibitor that inhibits the action of TIM-3.TIM-3-IN-2 reverses TIM-3-mediated pro-inflammatory cytokine effects.</p>Formula:C25H23N3O6Purity:98.93%Color and Shape:SolidMolecular weight:461.47TLR8 agonist 6
CAS:<p>Compound A, a potent TLR8 agonist, exhibits an EC50 of 0.052 µM and promotes the production of IL-12p40 in human PBMCs with an EC50 of 0.031 µM.</p>Formula:C19H29N7O2Color and Shape:SolidMolecular weight:387.48Lobenzarit sodium
CAS:<p>Lobenzarit sodium (CCA) is an agent with the activity of antirheumatic and antioxidative.</p>Formula:C14H8ClNNa2O4Purity:99.35%Color and Shape:SolidMolecular weight:335.65IRAK inhibitor 3
CAS:<p>IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.</p>Formula:C21H21N5O4SPurity:98.86%Color and Shape:SolidMolecular weight:439.49CGA-JK3
CAS:<p>CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.</p>Formula:C15H19NO3Purity:98%Color and Shape:SolidMolecular weight:261.323M-011
CAS:<p>3M-011: potent TLR7/8 agonist, cytokine inducer, enhances radiotherapy, fights H3N2, and has anti-tumor effects.</p>Formula:C18H25N5O3SPurity:98%Color and Shape:SolidMolecular weight:391.49Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Formula:C16H12ClNO3Purity:98.87%Color and Shape:SolidMolecular weight:301.72Stobadine
CAS:<p>Stobadine, a potent antioxidant, safeguards endoplasmic reticulum (ER) membrane fluidity against free radical-induced changes.</p>Formula:C13H18N2Purity:98%Color and Shape:SolidMolecular weight:202.3NLRP3-IN-17
CAS:<p>NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM.</p>Formula:C21H22N4O2SPurity:98%Color and Shape:SolidMolecular weight:394.49HBF-0259
CAS:<p>HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.</p>Formula:C16H12Cl2FN5Purity:98.07% - 99.42%Color and Shape:SolidMolecular weight:364.2TLR7 agonist 4
CAS:<p>TLR7 agonist 4 (Compound 1.2) is a TLR7 agonist (EC50: 4.3 nM).</p>Formula:C23H34N6O3Color and Shape:SolidMolecular weight:442.55NT-0796
CAS:<p>NT-0796 is an inflammasome NLRP3 inhibitor that inhibits NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.</p>Formula:C23H27N3O4Purity:99.67%Color and Shape:SolidMolecular weight:409.48C5aR-IN-1
CAS:<p>C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.</p>Formula:C36H39F4N3O2Color and Shape:SolidMolecular weight:621.71Fendosal
CAS:<p>Fendosal (HP-129), NSAID, 6.9-9.5x stronger than aspirin in chronic inflammation models.</p>Formula:C25H19NO3Purity:99.3%Color and Shape:SolidMolecular weight:381.42TMV-IN-5
CAS:<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Formula:C22H23N3SColor and Shape:SolidMolecular weight:361.5TLR7/8 agonist 9
CAS:<p>TLR7/8 agonist 9 (Compound 25a), exhibiting EC50 values of 40 nM and 23 nM for hTLR7 and hTLR8 respectively, demonstrates anti-tumor properties and enhances the</p>Formula:C20H26N6OColor and Shape:SolidMolecular weight:366.46Veledimex racemate
CAS:<p>Veledimex racemate, the racemic form of veledimex, is an orally available, small-molecule ligand that activates the RheoSwitch Therapeutic System.</p>Formula:C27H38N2O3Purity:98%Color and Shape:SolidMolecular weight:438.6Caspase-3 activator 1
<p>Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage.</p>Formula:C28H27N6O2RuS2Purity:98%Color and Shape:SolidMolecular weight:644.75(S)-BI 665915
CAS:<p>(S)-BI 665915 is an orally active inhibitor of oxadiazole-containing 5-lipoxygenase-activating protein (FLAP)(IC50 of 1.7 nM for FLAP binding)..</p>Formula:C24H26N8O2Purity:98%Color and Shape:SolidMolecular weight:458.52AD 0261
CAS:<p>AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions.</p>Formula:C27H31F2N3OPurity:98%Color and Shape:SolidMolecular weight:451.55STING agonist-10
CAS:<p>STING agonist-10 is a potent activator of the STING small molecule cyclic urea class (EC50: 2600 nM).STING activation is a highly promising immunotherapy.</p>Formula:C25H20ClF4N3O2Color and Shape:SolidMolecular weight:505.89IKK-IN-1
CAS:<p>IKK-IN-1 is an inhibitor of IKK.</p>Formula:C22H26ClN3O4Purity:98%Color and Shape:SolidMolecular weight:431.91ACHP Hydrochloride
CAS:<p>ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.</p>Formula:C21H25ClN4O2Purity:99.83%Color and Shape:SolidMolecular weight:400.9AHR antagonist 4
CAS:<p>AHR antagonist 4, potent with 82.2 nM IC50, inhibits AHR from patent WO2018146010A1 and shows anti-cancer properties.</p>Formula:C20H14F6N4O4Purity:98%Color and Shape:SolidMolecular weight:488.34BDW568
CAS:<p>BDW568, a prodrug of BDW-OH, serves as a stimulator of interferon genes (STING) agonist.</p>Formula:C12H12N4O2S2Color and Shape:SolidMolecular weight:308.38JNJ-67856633
CAS:<p>JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease .</p>Formula:C20H11F6N5O2Purity:99.87%Color and Shape:SolidMolecular weight:467.32(Rac)-BAY-985
CAS:<p>(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.</p>Formula:C27H30F3N9OPurity:98%Color and Shape:SolidMolecular weight:553.58TMV-IN-3
CAS:<p>TMV-IN-3 is a chalcone derivative that inhibits TMV with a 120.3 μg/mL EC50, used in research on infection and cancer.</p>Formula:C28H26O4Color and Shape:SolidMolecular weight:426.5α-Pyridoin
CAS:<p>α-Pyridoin (α-pyridoin) is an enediol (enediol) compound that acts as a unique antioxidant.</p>Formula:C12H12N2O2Color and Shape:SolidMolecular weight:216.24Lipid peroxidation inhibitor 1
CAS:<p>Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM).</p>Formula:C24H32N2OPurity:98%Color and Shape:SolidMolecular weight:364.52GW274150 phosphate
CAS:<p>GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 μM. It mitigates experimental renal ischaemia-reperfusion injury.</p>Formula:C8H20N3O6PSPurity:98%Color and Shape:SolidMolecular weight:317.3CCG-63802
CAS:<p>CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.</p>Formula:C26H18N4O2SPurity:90%Color and Shape:SolidMolecular weight:450.51STING-IN-7
CAS:<p>STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of</p>Formula:C16H14ClN3OPurity:98%Color and Shape:SolidMolecular weight:299.76MALT1-IN-6
CAS:<p>MALT1-IN-6 is a MALT1 protease inhibitor (Ki: 9 nM) that exhibits anticancer activity.</p>Formula:C18H12Cl2F3N9OColor and Shape:SolidMolecular weight:498.25PROTAC IRAK4 degrader-8
CAS:<p>PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].</p>Formula:C43H50ClF2N11O5Purity:98%Color and Shape:SolidMolecular weight:874.38FEN1-IN-6
CAS:<p>FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and additionally</p>Formula:C12H8N2O5S2Purity:98%Color and Shape:SolidMolecular weight:324.33GSK840
CAS:<p>GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase</p>Formula:C21H23N3O3Purity:99.7%Color and Shape:SolidMolecular weight:365.43Tyrosinase-IN-22
CAS:<p>Tyrosinase-IN-22 (compound 4) serves as a potent inhibitor for tyrosinase substrates, namely L-tyrosine and L-dopa, exhibiting inhibitory concentrations (IC50s) of 60 nM and 30 nM, respectively. Additionally, it demonstrates significant antioxidant and anti-melanogenic properties, making it suitable for related research endeavors [1].</p>Formula:C7H5ClN2SColor and Shape:SolidMolecular weight:184.64Anti-inflammatory agent 65
CAS:<p>Anti-inflammatory agent 65 (compound 29), a Hederagonic acid derivative, exhibits potent activity by inhibiting nitric oxide (NO) release, nuclear translocation</p>Formula:C49H71NO6S2Purity:98%Color and Shape:SoildMolecular weight:834.22Factor D inhibitor 6
CAS:<p>Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.</p>Formula:C23H22ClFN6O3Color and Shape:SolidMolecular weight:484.92GW274150 dihydrochloride
CAS:<p>GW274150 (dihydrochloride) is a potent, selective inhibitor of human and rat inducible nitric oxide synthase (iNOS), exhibiting oral activity and NADPH-</p>Formula:C8H19Cl2N3O2SPurity:98%Color and Shape:SolidMolecular weight:292.23TLR7 agonist 15
CAS:<p>TLR7 agonist 15 (compound 16b) is a potent activator of mouse macrophages and hPBMCs, demonstrating an EC50 of 18 nM.</p>Formula:C26H31N5OColor and Shape:SolidMolecular weight:429.56CAY10464
CAS:<p>CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.</p>Formula:C15H12Cl2OPurity:99.96%Color and Shape:SolidMolecular weight:279.16IR-Crizotinib
CAS:<p>IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranial</p>Formula:C53H57Cl2FIN7OPurity:98%Color and Shape:SolidMolecular weight:1024.88Cergutuzumab amunaleukin
CAS:<p>Cergutuzumab amunaleukin (CEA-IL2v) is a CEA-targeted IL-2 variant immunocytokine for combination cancer immunotherapy with anti-tumor activity.</p>Purity:98% (SDS-PAGE); 99.7% (SEC-HPLC) - 98% (SDS-PAGE); 99.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:162.05 kDaIL-17A antagonist 3
CAS:<p>IL-17A antagonist 3 is an IL-17A antagonist.</p>Formula:C33H33ClN6O4Purity:98%Color and Shape:SolidMolecular weight:613.11RIPK1-IN-16
CAS:<p>RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo.</p>Formula:C20H19N5O2SPurity:98%Color and Shape:SolidMolecular weight:393.46STING agonist-11
CAS:<p>STING agonist-11 is a potent activator of the small molecule cyclic urea class of STING (EC50: 18 nM).STING activation is a highly promising immunotherapy.</p>Formula:C25H20ClF4N3O2Color and Shape:SolidMolecular weight:505.89Oxidized ATP trisodium salt
CAS:<p>Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (</p>Formula:C10H11N5Na3O13P3Purity:98%Color and Shape:SolidMolecular weight:571.11PDE4-IN-8
CAS:<p>PDE4-IN-8 is a potent PDE4 inhibitor with IC50 0.93 nM for PDE4B2 and minor impact on IL13, IL4, IFNy (IC50: 4.04, 36.33, 2394 nM).</p>Formula:C18H22BNO4Color and Shape:SolidMolecular weight:327.18MKA031
CAS:<p>MKA031 (compound 6y) is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.7 μM.</p>Formula:C21H17N5O2SColor and Shape:SolidMolecular weight:403.46IRAK4-IN-6
CAS:<p>IRAK4-IN-6 is an oral IRAK4 inhibitor with a 4 nM IC50, targeting MyD88 L265P mutant DLBCL.</p>Formula:C25H32N10O2Purity:98%Color and Shape:SolidMolecular weight:504.59TLR9-IN-1
CAS:<p>TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.</p>Formula:C23H31N7OColor and Shape:SolidMolecular weight:421.54Leteprinim
CAS:<p>Leteprinim (AIT 082 acid) is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from</p>Formula:C15H13N5O4Purity:99.08%Color and Shape:SolidMolecular weight:327.29FEN1-IN-7
CAS:<p>FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells.</p>Formula:C16H14N2O6SPurity:98%Color and Shape:SolidMolecular weight:362.36Ginsenoside Rk1
CAS:<p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>Formula:C42H70O12Purity:98.46% - 99.13%Color and Shape:SolidMolecular weight:767WEHI-345
CAS:<p>WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.</p>Formula:C22H23N7OPurity:>99.99%Color and Shape:SolidMolecular weight:401.46GGTI 2147
CAS:<p>GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.</p>Formula:C28H30N4O3Purity:98.69%Color and Shape:SolidMolecular weight:470.56BRP-201
CAS:<p>BRP-201: selective mPGES-1 inhibitor (IC50: 0.42 μM), potential next-gen anti-inflammatory drug.</p>Formula:C28H27ClN4OSColor and Shape:SolidMolecular weight:503.06Vipoglanstat
CAS:<p>Vipoglanstat: inhibits prostaglandin E synthase, anti-inflammatory, reduces leukocyte infiltration and lung injury from endotoxin/sepsis.</p>Formula:C30H34Cl2F5N5O3Color and Shape:SolidMolecular weight:678.52FEN1-IN-5
CAS:<p>FEN1-IN-5 (compound 12A) is a potent Flap endonuclease-1 (FEN1) inhibitor with an IC50 value of 12 nM, playing a role in DNA repair mechanisms [1].</p>Formula:C21H17N3O4SPurity:98%Color and Shape:SolidMolecular weight:407.44EG01377
CAS:<p>EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.</p>Formula:C26H30N6O6S2Purity:98%Color and Shape:SolidMolecular weight:586.68TLR7 agonist 16
CAS:<p>TLR7 agonist 16 (compound 16d) is a potent activator of TLR7 with an EC50 value of 18 nM.</p>Formula:C25H29N5O2Color and Shape:SolidMolecular weight:431.53STING modulator-3
CAS:<p>STING modulator-3, a 43.1 nM R232 STING inhibitor, doesn't affect IRF-3 or TNF-β in THP-1 cells.</p>Formula:C18H17N9OColor and Shape:SolidMolecular weight:375.39cGAS-IN-1
CAS:<p>cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM</p>Formula:C18H19NO8Color and Shape:SolidMolecular weight:377.35Nrf2-IN-3
CAS:<p>Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to cisplatin.</p>Formula:C22H26N4O4SPurity:98.07%Color and Shape:SolidMolecular weight:442.53ABR-238901
CAS:<p>ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products</p>Formula:C11H9BrClN3O4SPurity:98.63% - 98.71%Color and Shape:SolidMolecular weight:394.63LTβR-IN-1
CAS:<p>LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor.</p>Formula:C18H16N4O2Purity:98.93%Color and Shape:SolidMolecular weight:320.35Iptacopan
CAS:<p>Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM. Cost-effective and quality-assured.</p>Formula:C25H30N2O4Purity:99.07% - >99.99%Color and Shape:SolidMolecular weight:422.52Xanthine oxidase-IN-10
CAS:<p>Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout.</p>Formula:C10H8N2OSPurity:99.16%Color and Shape:SolidMolecular weight:204.25AVP-13358
CAS:<p>AVP-13358: a CD23/IgE inhibitor for treating immune, infection, and ENT disorders.</p>Formula:C30H29N5O2Purity:98.42%Color and Shape:SolidMolecular weight:491.58ERDRP-0519
CAS:<p>ERDRP-0519 is an oral measles polymerase inhibitor, preventing disease in monkeys, with potent nanomolar efficacy against morbilliviruses.</p>Formula:C23H30F3N5O4SPurity:98.64% - 98.71%Color and Shape:SolidMolecular weight:529.58CU-CPD107
CAS:<p>CU-CPD107 selectively activates TLR8 and ssRNA, inhibits TLR8 with R848 (IC50=13.7 μM), and coactivates with ssRNA.</p>Formula:C16H21IN2O2Purity:98%Color and Shape:SolidMolecular weight:400.25Sembragiline
CAS:<p>Sembragiline (EVT-302) is a selective MAO-B inhibitor for the study of Alzheimer's disease (AD).</p>Formula:C19H19FN2O3Purity:99.49% - 99.49%Color and Shape:SolidMolecular weight:342.36RIPK1-IN-4
CAS:<p>RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s</p>Formula:C23H23N5O2Purity:99.94%Color and Shape:SolidMolecular weight:401.46Netakimab
CAS:<p>Netakimab (BCD 085) is a monoclonal antibody targeting interleukin-17A and can be used to study spondyloarthritis.</p>Purity:95%Color and Shape:LiquidMolecular weight:145.74 kDaGW274150
CAS:<p>GW274150: selective oral iNOS inhibitor (Kd=40 nM), low activity on eNOS/nNOS, protective in acute lung injury.</p>Formula:C8H17N3O2SPurity:96.43%Color and Shape:SolidMolecular weight:219.3IL-17 modulator 4
CAS:<p>IL-17 modulator 4 is a prodrug of IL-17 modulator 1, which acts as a potent modulator of IL-17.Cost-effective and quality-assured.</p>Formula:C27H34N6O2Purity:99.59%Color and Shape:SolidMolecular weight:474.6Piflufolastat
CAS:<p>Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA.</p>Formula:C18H23FN4O8Purity:98.98%Color and Shape:SolidMolecular weight:442.4Antiviral agent 34
CAS:<p>Antiviral Agent 34 is an antiviral compound that inhibits influenza virus and inhibits the proliferation of influenza virus by modulating RNA polymerase.</p>Formula:C29H33N3O2SPurity:99.51%Color and Shape:SoildMolecular weight:487.66Usnoflast
CAS:<p>Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.</p>Formula:C21H29N3O3SPurity:98.79%Color and Shape:SolidMolecular weight:403.54Supercinnamaldehyde
CAS:<p>Supercinnamaldehyde is a potent activator of transient receptor potential ankyrin 1 (TRPA1), exhibiting an EC50 of 0.8 μM, and induces activation of TRPA1 ion</p>Formula:C12H11NO2Purity:98.89%Color and Shape:SolidMolecular weight:201.22GB1107
CAS:<p>GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM.</p>Formula:C20H16Cl2F3N3O4SPurity:98.33% - 99.87%Color and Shape:SolidMolecular weight:522.32Oditrasertib
CAS:<p>Oditrasertib, a RIPK1 inhibitor characterized by an IC50 value below 100 nM, is employed in inflammation research.</p>Formula:C14H15F2N3O2Purity:98.65% - 99.65%Color and Shape:SolidMolecular weight:295.28ADS032
CAS:<p>ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity for the study of respiratory inflammation or infection.</p>Formula:C22H29NO4SPurity:98.37%Color and Shape:SolidMolecular weight:403.54(±)-CPSI-1306
CAS:<p>(±)-CPSI-1306 (2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one) is a macrophage migration inhibitory factor (MIF) antagonist and can</p>Formula:C15H16F2N2O3Purity:97.46%Color and Shape:SolidMolecular weight:310.3COX-2/15-LOX-IN-5
CAS:<p>COX-2/15-LOX-IN-5 (Compound 4f) functions as a dual inhibitor of COX-2 and 15-LOX, demonstrating both anti-inflammatory and antioxidant properties [1]. This compound effectively reduces NF-κB activation in RAW 264.7 macrophages that is induced by lipopolysaccharide.</p>Formula:C25H21N3O3SColor and Shape:SolidMolecular weight:443.52MG-T-19
CAS:<p>MG-T-19, a TIM-3 inhibitor, inhibit the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9, and increased the production of TNF-α and IFN-γ in PBMCs.</p>Formula:C18H8Br2ClF3N4O2SPurity:99.14%Color and Shape:SolidMolecular weight:596.6CVN293
CAS:<p>CVN293 is a inhibitor of the potassium channel KCNK13,BBB,It inhibits the production of the pro-inflammatory cytokine IL-1β induced by NLRP3 in microglia</p>Formula:C14H10FN7OPurity:99.50%Color and Shape:SolidMolecular weight:311.27Heme Oxygenase-1-IN-2
<p>Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.</p>Formula:C19H18ClN3OColor and Shape:SolidMolecular weight:339.82C-di-IMP
CAS:<p>Cyclic-di-IMP (C-di-IMP), a STING agonist, serves as a research tool in tumor studies.</p>Formula:C20H22N8O14P2Color and Shape:SolidMolecular weight:660.38NLRP3-IN-80
CAS:<p>NLRP3-IN-80 (Compound 1) is an NLRP3 inhibitor useful for research into inflammatory aging.</p>Formula:C24H22F2N4O3Color and Shape:SolidMolecular weight:452.45Galectin-3-IN-3
CAS:<p>Galectin-3-IN-3 (Compound 4) serves as a selective and orally active inhibitor targeting Gal-3. It exhibits IC50 values of 11 nM for mGal-3 and 84 nM for hGal-3 [1].</p>Formula:C25H22ClF2N7O4SColor and Shape:SolidMolecular weight:590.00MMG-11 quarterhydrate
<p>MMG-11 quarterhydrate, a potent hTLR2 antagonist, inhibits TLR2/1 and TLR2/6 with IC50s of 1.7μM and 5.7μM; low toxicity.</p>Formula:C15H16O8Color and Shape:SolidMolecular weight:310.78PB01
CAS:<p>PB01 is a DPP-4 inhibitor with an IC50 of 15.66 nM. It effectively suppresses high glucose-induced ROS generation and mitochondrial superoxide production while significantly reducing the cellular expression of DPP-4. Additionally, PB01 notably lowers blood glucose levels in diabetic mice. It demonstrates excellent safety, exhibiting almost no cytotoxicity at a concentration of 100 μM. PB01 holds promise for research in the diabetes field.</p>Formula:C18H21N5O3Color and Shape:SolidMolecular weight:355.391ALR-6
CAS:<p>ALR-6, an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP, possesses anti-inflammatory properties. It significantly inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM without substantially affecting direct inhibition of 5-LOX [1].</p>Formula:C18H14O5Color and Shape:SolidMolecular weight:310.3AhR agonist 7
CAS:<p>Compound 8, an AhR agonist 7, demonstrates potent activation of AhR with an EC50 of 13nM [1].</p>Formula:C16H15ClFNO2Color and Shape:SolidMolecular weight:307.75(Rel)-Factor B-IN-5
CAS:<p>(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.</p>Formula:C27H32N2O4Purity:>99.99%Color and Shape:SolidMolecular weight:448.55COX-2-IN-12
<p>COX-2-IN-12: Potent, selective COX-2 inhibitor, IC50=19.98μM, safe anti-inflammatory with low acute toxicity.</p>Formula:C17H19NO3Color and Shape:SolidMolecular weight:285.34XO/COX/LOX-IN-1
<p>XO/COX/LOX-IN-1 targets XO/COX/LOX, used in research of inflammation, cancer, and metabolic disorders.</p>Formula:C24H20N4O2SColor and Shape:SolidMolecular weight:428.51Ac5GalNTGc
CAS:<p>Ac5GalNTGc, an analog of hexosamine, inhibits mucin-type O-linked glycosylation biosynthesis [1].</p>Formula:C18H25NO11SColor and Shape:SolidMolecular weight:463.46Factor B-IN-4
CAS:<p>Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.</p>Formula:C27H32N2O4Color and Shape:SolidMolecular weight:448.55Polvitolimod
CAS:<p>Polvitolimod is a TLR7 agonist used to treat infectious disease and cancer.</p>Formula:C13H14FN5O4Color and Shape:SolidMolecular weight:323.28ODN 2088
CAS:<p>ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.</p>Color and Shape:SolidTLR7/8 antagonist 2
<p>TLR7/8 antagonist 2: potent, orally active, IC50: 4.9 nM (TLR7), 0.6 nM (TLR8); potential for lupus therapy research.</p>Formula:C22H26FN5Color and Shape:SolidMolecular weight:379.47YE6144
CAS:<p>YE6144, IRF5 phosphorylation blocker. Affordable Excellence: Reliable Quality You Can Trust</p>Formula:C21H27ClFN7OColor and Shape:SolidMolecular weight:447.94Anti-inflammatory agent 10
<p>Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.</p>Formula:C17H13BrN4O3S2Color and Shape:SolidMolecular weight:465.34COX-2-IN-13
<p>COX-2-IN-13 is a potent, selective COX-2 inhibitor with 0.98 μM IC50; shows strong anti-inflammatory properties and low acute toxicity.</p>Formula:C19H18N2O5SColor and Shape:SolidMolecular weight:386.42Galectin-3-IN-4
CAS:<p>Galectin-3-IN-4 (compound 5), a carboxamide analog, effectively and selectively inhibits both human and mouse galectin-3. This compound demonstrates notable potency with IC50 values of 21 nM for hGal-3 and 167 nM for mGal-3. It is also orally bioavailable. For other galectins, Galectin-3-IN-4 shows IC50 values of 1580 nM for hGal-1 and 2750 nM for hGal-9, respectively [1].</p>Formula:C24H22ClF2N5O5SColor and Shape:SolidMolecular weight:565.98IKZF1-degrader-1
CAS:<p>IKZF1-degrader-1 (Compound 9-B) serves as a potent degrader of the IKZF1 protein, exhibiting a DC50 of 0.134 nM. It is applicable in the degradation of tumors [1].</p>Formula:C35H29F2N5O3Color and Shape:SolidMolecular weight:605.63Corannulene
CAS:<p>Corannulene is an agonist of the aromatic hydrocarbon receptor (AhR). It induces a lower cytotoxic response in liver cancer cells compared to Benzo[a]pyrene and shows potential for use in cancer research.</p>Formula:C20H10Color and Shape:SolidMolecular weight:250.293AS2690168 hydrochloride
CAS:<p>AS2690168 hydrochloride is an orally active inhibitor of RANKL signaling that can suppress RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.</p>Formula:C17H15Cl2F3N4OColor and Shape:SolidMolecular weight:419.228MAY0132
CAS:<p>MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.</p>Formula:C16H15ClF3NColor and Shape:SolidMolecular weight:313.745
