Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3035 products of "Immunology and Inflammation"
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BMX-010
CAS:<p>BMX-010, also known as AEOL-10113, is Porphyrin-Based SOD Mimic.</p>Formula:C48H44Cl5MnN8Color and Shape:SolidMolecular weight:965.12QX-005N
<p>QX 005N is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. It is applicable in research related to asthma.</p>Color and Shape:Odour LiquidAnti-MRC2/CD280 Antibody
<p>Anti-MRC2/CD280 Antibody is a humanized anti-MRC2/CD280 antibody that can be used in immunoblotting (WB) and immunohistochemistry experiments.</p>Purity:99.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:Odour LiquidNOD1 antagonist-2
<p>NOD1antagonist-2 (compound 66) is an orally active and selective inhibitor that can suppress NOD1 in both humans and mice. It effectively blocks the NOD1-induced NF-κB and MAPK pathways.</p>Formula:C21H13Cl2F2N3O5S2Color and Shape:SolidMolecular weight:560.378MyD88-IN-2
<p>MyD88-IN-2 (compound A5S) is a MyD88 inhibitor with a Kd value of 15 μM. It demonstrates protective effects in mouse models of acute lung injury induced by LPS and sepsis.</p>Formula:C22H26BrN3O2Color and Shape:SolidMolecular weight:444.3654-hydroperoxy 2-Nonenal
CAS:<p>4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.</p>Formula:C9H16O3Color and Shape:SolidMolecular weight:172.224LL-37 GKE acetate
<p>LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.</p>Formula:C121H206N38O30Purity:99.88%Color and Shape:SolidMolecular weight:2673.17TLR7/8 agonist 4 TFA
CAS:<p>TLR7/8 agonist 4 TFA (compound 41) is a highly potent TLR7/8 agonist that exhibits significant anti-cancer activity.</p>Formula:C20H25F3N6O2Color and Shape:SolidMolecular weight:438.45hSTING agonist-1
<p>hSTING agonist-1 (compound 17) is a potent activator of hSTING. It has poor oral bioavailability but plays a significant role in inflammation research.</p>Formula:C18H18F3N5O3SColor and Shape:SolidMolecular weight:441.427TP508
CAS:<p>TP508 (Chrysalin), a 23-amino-acid peptide from human prothrombin, aids in tissue repair, targeting thrombin receptors.</p>Formula:C97H146N28O36SPurity:98%Color and Shape:SolidMolecular weight:2312.44IKKγ NBD Inhibitory Peptide
CAS:<p>A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF</p>Formula:C170H259N49O42S1Purity:98%Color and Shape:SolidMolecular weight:3693.3NLRP3-IN-68
<p>NLRP3-IN-68 (Compound 2d) is a derivative of 1,3,4-oxadiazole. It exhibits significant anti-inflammatory and antioxidant properties, effectively inhibiting the secretion of inflammatory cytokines, the expression of iNOS, and the activation of the NLRP3 inflammasome. NLRP3-IN-68 is applicable in the research of anti-inflammatory drugs.</p>Formula:C18H15FN2O3Color and Shape:SolidMolecular weight:326.3223-O-(2'E,4'Z-Decadienoyl)ingenol
<p>3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.</p>Formula:C30H42O6Color and Shape:SolidMolecular weight:498.66Keap1-Nrf2-IN-27
<p>Keap1-Nrf2-IN-27 is an inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with a KD2 value of 0.119 μM. It suppresses the expression of pro-inflammatory cytokines TNF-α and IL-6 in an LPS-induced RAW264.7 cell model.</p>Color and Shape:Odour SolidDOPAL
CAS:<p>DOPAL, a neurotoxic aldehyde from dopamine metabolism, is linked to Parkinson's and can convert to DOPAC or DOPET.</p>Formula:C8H8O3Color and Shape:SolidMolecular weight:152.15MAPK-IN-4
<p>MAPK-IN-4 (Compound c1) is an orally active anti-inflammatory agent that inhibits the expression and release of pro-inflammatory cytokines IL-6 and TNF-α induced by LPS. It interacts with IRAK4 to exert its anti-inflammatory effects by inhibiting the MAPK pathway.</p>Color and Shape:Odour SolidMUC5AC motif peptide
<p>MUC5AC motif peptide is a 16-amino acid fragment of mucin 5.</p>Formula:C63H104N16O26Purity:98%Color and Shape:SolidMolecular weight:1501.62BAY-069
CAS:<p>BAY-069 blocks BCAT1 (IC50:31 nM) & BCAT2 (IC50:153 nM), useful for cancer research.</p>Formula:C22H14ClF3N2O3Purity:99.58%Color and Shape:SoildMolecular weight:446.81FITC-labeled Agatolimod sodium
<p>FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Color and Shape:Odour SolidHuMax-IL8
<p>HuMax-IL8 (MDX 018) is a humanized anti-IL-8 monoclonal antibody for the study of metastatic or unresectable solid tumors.</p>Purity:98.8% (SDS-PAGE); 97.4% (SEC-HPLC) - 98.8% (SDS-PAGE); 97.4% (SEC-HPLC)Color and Shape:Odour LiquidRH-EDA
<p>RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems.</p>Formula:C28H25N3O4Color and Shape:SolidMolecular weight:467.52Inbakicept
CAS:<p>Inbakicept (ALT 803) is a fusion protein of the IL-15 receptor 伪-sushi binding domain IL-15R伪Su and immunoglobulin G1 (human Fc fragment).</p>Purity:98.94%Color and Shape:LiquidROS inducer 6
<p>ROS inducer 6 (compound 9) acts as a reactive oxygen species (ROS) inducer by depleting intracellular glutathione, thereby functioning as an antitumor agent.</p>Formula:C32H26N2O3Color and Shape:SolidMolecular weight:486.56ZL-1102
<p>ZL-1102 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). SCH-900117 is being investigated for its potential use in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis.</p>Color and Shape:Odour LiquidMCC950
CAS:<p>MCC950 (CP-456773) is a NLRP3 inflammasome inhibitor (IC50=7.5-8.1 nM). MCC950 can be used to treat inflammatory diseases. High-Quality, Low-Cost!</p>Formula:C20H24N2O5SPurity:97% - 98%Color and Shape:SolidMolecular weight:404.48Prifelone
CAS:<p>Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity.</p>Formula:C19H24O2SPurity:99.8%Color and Shape:SolidMolecular weight:316.46Neuroprotective agent 8
<p>Neuroprotective agent 8 (compound AA-9) is an orally active neuroprotective agent that functions through antioxidant stress reduction and anti-inflammatory mechanisms. In a rat model of MCAO ischemic stroke, it activates PGC-1α and inhibits the NLRP3 inflammasome.</p>Color and Shape:Odour Solid17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
CAS:<p>DPA metabolite 17-oxo-DPA, found in fish oil, spurs antioxidant genes, modulates inflammation, and activates PPARγ (EC50 ≈ 200 nM).</p>Formula:C22H32O3Color and Shape:SolidMolecular weight:344.495ODN 2395
CAS:<p>ODN 2395, a class C oligodeoxynucleotide and TLR9 agonist, serves as a vaccine adjuvant. Its sequence is 5'-tcgtcgttttcggcgc:gcgccg-3' [1].</p>Color and Shape:SolidMolecular weight:7035RC529-MDP
<p>RC529-MDP is an immunological adjuvant that couples Toll-like receptors (TLR4a) and NOD-like receptors (NOD2a) to enhance the innate immune response through the TLR4 and NOD2 signaling pathways. In mouse models, RC529-MDP induces high levels of the cytokine interleukin-related factor (IL-6), highlighting its immunostimulatory activity. Additionally, when injected into mice models with ovalbumin (OVA), RC529-MDP elevates OVA-specific antibody responses, T cell responses, and the proportion of memory T cells.</p>Formula:C118H215N10O28PColor and Shape:SolidMolecular weight:2252.99Topramezone
CAS:<p>Topramezone is a 4-HPPD inhibitor herbicide for post-emergence weed control in corn.</p>Formula:C16H17N3O5SColor and Shape:SolidMolecular weight:363.39GB2095
<p>GB2095 is an orally effective and selective inhibitor of galectin-3, exhibiting binding affinities (Kd) of 36 nM for human galectin-3 and 0.35 μM for mouse galectin-3. In mouse models, GB2095 demonstrates antitumor activity.</p>Formula:C20H17BrClF2N3O4SColor and Shape:SolidMolecular weight:548.785STING agonist-28
CAS:<p>STING agonist-28 (CF510), a non-nucleotide, boosts STING, TBK1, IRF3 phosphorylation, and cytokines; active against SARS-CoV.</p>Formula:C39H46N14O6Color and Shape:SolidMolecular weight:806.87STING agonist-31
CAS:<p>STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively,</p>Formula:C43H51N15O6Color and Shape:SolidMolecular weight:873.96Redaporfin
CAS:<p>Redaporfin (F-2BMet, LUZ-11) is a PDT cancer photosensitizer; 83% of mice had tumor regression with 1.5 mg/kg and 74 J/cm² light.</p>Formula:C48H38F8N8O8S4Color and Shape:SolidMolecular weight:1135.11Romurtide
CAS:<p>Romurtide is a synthetic muramyl dipeptide analog and can be used for the prophylaxis of leukocytopenia during radiation therapy.</p>Formula:C43H78N6O13Purity:98%Color and Shape:SolidMolecular weight:887.126Anti-IL11RA Antibody (X209)
<p>Anti-IL11RA Antibody (X209) is a human-derived IgG4, κ type antibody inhibitor targeting human IL-11RA.</p>Color and Shape:Odour LiquidBiotin-labeled ODN 1668 sodium
<p>Biotin-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>Color and Shape:Odour SolidSARS-CoV-2-IN-107
<p>SARS-CoV-2-IN-107 (Compound A7) is an inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 261.3 nM. It inhibits the replication of SARS-CoV-2, exhibiting an EC50 of 11.7 μM. Additionally, SARS-CoV-2-IN-107 demonstrates anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages, with a NO inhibition rate of 68.6%.</p>Formula:C15H11FO4Color and Shape:SolidMolecular weight:274.244Reslizumab
CAS:<p>Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.</p>Purity:98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)Color and Shape:LiquidMolecular weight:N/AEramkafusp Alfa
<p>Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].</p>Color and Shape:Odour LiquidIACS-8803 diammonium
<p>IACS-8803 diammonium, a potent cyclic dinucleotide STING agonist, demonstrates robust systemic antitumor efficacy [1].</p>Formula:C20H29FN12O9P2S2Color and Shape:SolidMolecular weight:726.6Factor B-IN-1
CAS:<p>Factor B-IN-1 is a Factor B inhibitor.</p>Formula:C19H16N4O2Color and Shape:SolidMolecular weight:332.3559KTX-955
CAS:<p>KTX-955, a potent IRAK4 degrader, exhibits DC50 values of 5 nM for IRAK4 and 130 nM for Ikaros. It is primarily utilized in anticancer research [1] [2].</p>Formula:C46H51F3N8O7Color and Shape:SolidMolecular weight:884.94Pegaldesleukin
CAS:<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Color and Shape:LiquidNosantine racemate
CAS:<p>Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).</p>Formula:C14H22N4O2Purity:98%Color and Shape:SolidMolecular weight:278.35TLR8 agonist 8
CAS:<p>TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.</p>Formula:C53H63N11O10Color and Shape:SolidMolecular weight:1014.1424-Methylenecholesterol
CAS:<p>24-Methylenecholesterol (24 Methylenecholesterol) is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages.</p>Formula:C28H46OPurity:98%Color and Shape:SolidMolecular weight:398.66FM101
<p>FM101 is a humanized monoclonal anti-IL6 antibody, suitable for use in asthma-related research.</p>Color and Shape:Odour LiquidAHR Inhibitor I-103
CAS:<p>AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.</p>Formula:C21H17FN6Purity:98.70%Color and Shape:SoildMolecular weight:372.4ATWLPPR Peptide TFA
<p>ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.</p>Formula:C42H62F3N11O11Purity:98%Color and Shape:SolidMolecular weight:954Complement C1s-IN-1
CAS:<p>Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexes</p>Formula:C22H20F2N6OPurity:97.77%Color and Shape:SoildMolecular weight:422.43c-di-AMP disodium
CAS:<p>c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.</p>Formula:C20H22N10Na2O12P2Color and Shape:SolidMolecular weight:702.38MRT67307
CAS:<p>Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.</p>Formula:C26H36N6O2Purity:99.25% - 99.84%Color and Shape:SolidMolecular weight:464.6Balekafusp alfa
CAS:<p>Balekafusp alfa is a human IgG1κ antibody targeting IL-2, known for its antitumor properties.</p>Color and Shape:LiquidTimosaponin E2
CAS:<p>Timosaponin E2 is an anti-inflammatory agent that inhibits active oxygen production [1].</p>Formula:C46H78O20Color and Shape:SolidMolecular weight:951.1Human Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Color and Shape:Odour SolidVemircopan
CAS:<p>Vemircopan is a complement factor D inhibitor.</p>Formula:C29H28BrN7O3Color and Shape:SolidMolecular weight:602.493Dazostinag
CAS:<p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>Formula:C21H22F2N8O10P2S2Color and Shape:SolidMolecular weight:710.52Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formula:C16H12O5Color and Shape:SolidMolecular weight:284.267Ac-macropa
<p>Ac-macropa is a conjugate of Actinium-225 that targets PSMA, and it is useful for researching prostate cancer.</p>Formula:C39H52AcN6O9SMolecular weight:1007.3794TBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Formula:C31H36F2N8O4Color and Shape:SolidMolecular weight:622.678(R)-(-)-Ibuprofen
CAS:<p>(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.</p>Formula:C13H18O2Purity:99.86%Color and Shape:SolidMolecular weight:206.282-O-Sinapoyl makisterone A
<p>Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectively</p>Formula:C39H56O11Purity:98%Color and Shape:SolidMolecular weight:700.86Glu-urea-Lys
CAS:<p>Glu-urea-Lys is a molecular scaffold that targets PSMA and can be used as a prostate cancer imaging agent to study prostate-specific membrane antigens.</p>Formula:C12H21N3O7Purity:99.40%Color and Shape:SolidMolecular weight:319.31Chitoheptaose heptahydrochloride
CAS:<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Formula:C42H80ClN7O29Color and Shape:SolidMolecular weight:1182.57FM-303
<p>FM-303 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It shows promise for research in immune system and digestive system diseases.</p>Color and Shape:Odour LiquidEfmarodocokin alfa
CAS:<p>Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.</p>Color and Shape:LiquidIFN-α Receptor Recognition Peptide 1
CAS:<p>IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.</p>Formula:C35H59N13O12SPurity:98%Color and Shape:SolidMolecular weight:885.99Anti-inflammatory agent 88
<p>Anti-inflammatory agent 88 (compound 6) is a carbazole derivative found in marine Streptomyces with anti-inflammatory properties. It exerts its effects by inhibiting pro-inflammatory factors and enhancing the expression of anti-inflammatory factors within the Myd88/Nf-κB pathway. This compound holds potential for the development of anti-inflammatory drugs.</p>Formula:C13H10BrNO2Molecular weight:290.98949STING agonist-24
CAS:<p>CF504: non-nucleotide STING agonist, boosts STING, TBK1, IRF3 phosphorylation; raises IFN-β, IL-6, CXCL-10, TNF-α; active against SARS-CoV strains.</p>Formula:C34H37N13O5Color and Shape:SolidMolecular weight:707.74STING agonist-27
CAS:<p>CF509 is a non-nucleotide STING agonist; it activates STING and combats SARS-CoV strains.</p>Formula:C40H50N14O6Color and Shape:SolidMolecular weight:822.92TLR7 agonist 17
CAS:<p>TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].</p>Formula:C25H37N7O3Color and Shape:SolidMolecular weight:483.61TLR4-IN-C34-C2-amide-C6-OH
<p>TLR4-IN-C34-C2-amide-C6-OH: a linker with TLR4-IN-C34 that curbs TLR4 and inflammation in mice.</p>Formula:C25H42N2O11Color and Shape:SolidMolecular weight:546.61M0324
<p>M0324 is a MUC-1 conditional CD40 agonist composed of an anti-MUC-1 IgG and two identical CD40-targeting camelid VHH domains, selectively activate immune cells.</p>Color and Shape:Odour LiquidHydroxychloroquine Impurity E
CAS:<p>Hydroxychloroquine Impurity E, a byproduct, can block TLR7/9 and inhibit SARS-CoV-2 in vitro.</p>Formula:C14H17ClN2OColor and Shape:SolidMolecular weight:264.75Dalutrafusp alfa
CAS:<p>Dalutrafusp alfa (AGEN-1423; GS-1423) is a bifunctional antibody targeting CD73 and TGF-β, components of the immunosuppressive pathway [1].</p>Color and Shape:LiquidNLRP3-IN-35
<p>NLRP3-IN-35 (compound 11) is an NLRP3 inhibitor with an IC50 of less than 1 μM.</p>Formula:C26H25FN4O2Molecular weight:444.19615BRD5075
<p>BRD5075 is an effective activator of GPR65, stimulating the production of cAMP in a GPR65-dependent manner. Additionally, it reduces the gene expression of IL-1, IL-2, TNF, and chemokines. BRD5075 holds potential for researching multiple sclerosis and inflammatory bowel disease (IBD).</p>Color and Shape:Odour Solid5(S),15(S)-DiHETE
CAS:<p>5(S),15(S)-DiHETE, made by 15-LO from 5(S)-HETE, boosts human PMNL degranulation via PAF, not fMLP/A23187/LTB4, and lures eosinophils at ED50 of 0.3μM.</p>Formula:C20H32O4Color and Shape:SolidMolecular weight:336.472Rabelomycin
CAS:<p>Rabelomycin is an angucycline group antibiotic.</p>Formula:C19H14O6Color and Shape:SolidMolecular weight:338.31Meliadubin B
<p>Meliadubin B, a natural triterpenoid, effectively inhibits inflammatory responses by suppressing superoxide anion generation in human neutrophils (EC 50 of 5.54</p>Formula:C30H48O4Purity:98%Color and Shape:SolidMolecular weight:472.7Anti-inflammatory agent 64
<p>Anti-inflammatory agent 64 (compound 4b) exhibits antioxidant and anti-inflammatory activities, effectively inhibiting the secretion of IL-6 and TNF-α while</p>Purity:98%Color and Shape:Odour SolidNOX4-IN-1
<p>NOX4-IN-1 (Compound 14m) is an inhibitor of NADPH oxidase 4 (NOX4) that reduces the production of reactive oxygen species (ROS). It also inhibits the TGF-β1/Smad signaling pathway, leading to decreased expression of fibrosis-related proteins. Additionally, NOX4-IN-1 impedes the migration of NRK-49F cells.</p>Formula:C26H16ClN3O3Color and Shape:SolidMolecular weight:453.877CAY10512
CAS:<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Formula:C15H13FOColor and Shape:SolidMolecular weight:228.266ROS-ERS inducer 1
<p>Type II ICD agent, ROS-ERS inducer 1, is a Pt(II)-NHC from 4,5-diarylimidazole, boosting ER stress, ROS, and DAMPs in HCC, outperforming Cisplatin.</p>Formula:C24H23F2I2N3PtColor and Shape:SolidMolecular weight:840.35DEPMPO-biotin
CAS:<p>DEPMPO is a stable nitrone for trapping O, N, S, C radicals, used in vivo/vitro with ESR. DEPMPO-biotin tags proteins' S-nitroso groups for analysis.</p>Formula:C24H42N5O8PSColor and Shape:SolidMolecular weight:591.66CDN-A
CAS:<p>CDN-A, a cyclic di-nucleotide, activates immune response & aids in ADC synthesis.</p>Formula:C22H29N11O12P2Color and Shape:SolidMolecular weight:701.48PROTAC IRAK4 degrader-5
CAS:<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Formula:C41H40F3N11O9Color and Shape:SolidMolecular weight:887.834Mifamurtide sodium
CAS:<p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>Formula:C59H108N6NaO19PPurity:98%Color and Shape:SolidMolecular weight:1259.48Croconazole
CAS:<p>Croconazole exhibited dose-dependent inhibitory activity on the 5-lipoxygenase (5-LOX) of neutrophils.</p>Formula:C18H15ClN2OPurity:99.71%Color and Shape:SolidMolecular weight:310.78Diplacol
CAS:<p>Diplacol, a geranylated flavanone isolated from Paulownia trees (Paulownia coreana UYEKI), exhibits anti-inflammatory properties by inhibiting NO production in LPS-stimulated Raw264.7 cells with an IC50 value of 4.53 μM [1].</p>Formula:C25H28O7Color and Shape:SolidMolecular weight:440.49SIN 14
<p>SIN 14 is an HO-1 activator that targets and activates HO-1 through an allosteric mechanism. Additionally, SIN 14 can induce the polarization of macrophages from the M1 phenotype to the M2 phenotype.</p>Formula:C20H22ClNO4Color and Shape:SolidMolecular weight:375.123746-Amyl-2-pyrone
CAS:<p>6-Amyl-2-pyrone exhibits inhibitory activity against tyrosinase, antibacterial and antiviral activity against Penicillium vulpinum and Aspergillus flavus, and antifungal activity against Sclerotinia sp.</p>Formula:C10H14O2Purity:99.00%Color and Shape:SolidMolecular weight:166.22CL097
CAS:<p>CL097 activates TLR7/8, spurs macrophage cytokines, and enhances ROS creation with fMLF.</p>Formula:C13H14N4OPurity:99.88%Color and Shape:SolidMolecular weight:242.28Peginterferon λ-1a
CAS:<p>Peginterferon lambda-1a (BMS-914143) is a monoclonal antibody that targets IFNLR1 and is composed of IFNL1 conjugated to pegol [1].</p>Purity:98%Color and Shape:LiquidAnti-inflammatory agent 60
<p>Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin</p>Purity:98%Color and Shape:Odour SolidAnticancer agent 15
CAS:<p>Anticancer agent 15 raises ROS, causing necroptosis in melanoma cells.</p>Formula:C35H40Cl2N2O5Color and Shape:SolidMolecular weight:639.61Anti-inflammatory agent 58
<p>Anti-inflammatory agent 58 exhibits IL-1β inhibition with an IC50 value of 1.08 μM and suppresses pro-inflammatory gene expression, protein secretion, and NF-κB</p>Color and Shape:Odour SolidCP-447697
CAS:<p>CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.</p>Formula:C29H26ClF2N3O2SPurity:99.90%Color and Shape:SoildMolecular weight:554.05TSR-033
CAS:<p>TSR-033 is a human IgG4 antibody with high affinity for LAG-3 (lymphocyte activation gene-3), a co-receptor linked to diminished T cell activity, frequently co-</p>Color and Shape:LiquidCD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Color and Shape:SolidR1-ICR-5
CAS:<p>R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.</p>Formula:C54H70N8O7S2Color and Shape:SolidMolecular weight:1007.314-Chlorochalcone
CAS:<p>4-Chlorochalcone is achalcone inhibit human MAO-B and ROS/RNS production and is able to inhibit the growth of CAL51 cells.</p>Formula:C15H11ClOPurity:98.08%Color and Shape:SolidMolecular weight:242.7Camstatin
CAS:<p>An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.</p>Formula:C122H203N39O34Purity:98%Color and Shape:SolidMolecular weight:2760.19ZSA-51
<p>ZSA-51 is an effective, orally active STING agonist with anticancer properties. It has the capability to remodel the immune microenvironment within tumors and lymph nodes.</p>Formula:C16H15NO6SColor and Shape:SolidMolecular weight:349.358COX-2/15-LOX-IN-4
<p>COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor with IC50 values of 0.075 μM for COX-2 and 1.97 μM for 15-LOX.</p>Formula:C23H20FN3OSPurity:98%Color and Shape:SolidMolecular weight:405.49C6 L-threo Ceramide (d18:1/6:0)
CAS:<p>C6 L-threo Ceramide: bioactive sphingolipid, cytotoxic to U937 cells (IC50=18μM), non-metabolic, boosts IL-4 in T cells at 10μM.</p>Formula:C24H47NO3Color and Shape:SolidMolecular weight:397.63NF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formula:C62H50N4O4SColor and Shape:SolidMolecular weight:947.15Ginger extract
CAS:<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Color and Shape:SolidRIPK2/3-IN-1
<p>RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3.</p>Formula:C24H16N4O2S2Purity:98%Color and Shape:SolidMolecular weight:456.54IVMT-Rx-3
<p>IVMT-Rx-3 is a chemical compound that serves as an inhibitor of SDCBP's targeting of the PDZ1 and PDZ2 domains of MDA-9/Syntenin.</p>Formula:C69H90F3N13O24Purity:98%Color and Shape:SoildMolecular weight:1542.54JT001 sodium
CAS:<p>JT001 (NLRP3-IN-19) sodium is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome, thus curbing cytokine</p>Formula:C19H22N4NaO4SPurity:98%Color and Shape:SolidMolecular weight:425.46(±)19(20)-EDP Ethanolamide
CAS:<p>(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively).</p>Formula:C24H37NO3Color and Shape:SolidMolecular weight:387.564STING modulator-5
CAS:<p>STING modulator-5: pIC50 9.5, antagonizes PBMC (pIC50 8.1), THP-1 cell antagonist, for immunology research.</p>Formula:C43H45F4N11O5Color and Shape:SolidMolecular weight:871.88Cartap hydrochloride
CAS:<p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>Formula:C18H33Cl2CuN3O3Color and Shape:Colorless Crystalline Slightly Hygroscopic Solid CoaMolecular weight:473.93Diprovocim-X
<p>Diprovocim-X, a potent TLR1/2 agonist, has EC50s of 0.14nM (hTLR) and 0.75nM (mTLR), enhances mice's adaptive immunity.</p>Formula:C66H83N7O10Color and Shape:SolidMolecular weight:1134.41Anti-inflammatory agent 38
<p>Compound 23d, an Nrf2/HO-1 inhibitor, with IC50 of 0.38 μM for NO, reduces cellular ROS for anti-inflammatory research.</p>Formula:C36H46N2O13SColor and Shape:SolidMolecular weight:746.82QX006N
<p>QX006N is a humanized monoclonal antibody inhibitor targeting the human interferon α/β receptor 1 (IFNAR1). It is promising for research in systemic lupus erythematosus (SLE) and other IFNAR1-related autoimmune diseases.</p>Color and Shape:Odour Liquid1-Hydroxy-ibuprofen
CAS:<p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>Formula:C13H18O3Color and Shape:SolidMolecular weight:222.2802Crocin-4
CAS:<p>Crocin-4, a saffron carotenoid, is an antioxidant that inhibits Aβ deposits in the brain and may aid Alzheimer's research with anti-tumor effects.</p>Formula:C27H36O9Color and Shape:SolidMolecular weight:504.576P2X7-IN-2 TFA
<p>P2X7-IN-2 TFA inhibits IL-Iβ release (IC50=0.01nM), used in autoimmunity, inflammation & cardiovascular research.</p>Formula:C24H22F7N3O4Color and Shape:SolidMolecular weight:549.44ATV006
CAS:<p>SHEN26 has antiviral activity and can be used in research on the treatment of viral infections.</p>Formula:C16H19N5O5Purity:99.58%Color and Shape:SolidMolecular weight:361.35TMX-201
CAS:<p>TMX-201: TLR7 ligand-phospholipid with potent immune-boosting effect; for breast cancer & melanoma study.</p>Formula:C57H93N6O12PColor and Shape:SolidMolecular weight:1085.36IMGN-779
<p>IMGN-779 (Anti-CD33 Antibody) is a humanized antibody targeting CD33 with antileukemic activity, which can be used to study leukemia.</p>Purity:>95%Color and Shape:Odour Liquid3-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formula:C30H44O7SColor and Shape:SolidMolecular weight:548.737-epi Maresin 1
CAS:<p>7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 , which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.</p>Formula:C22H32O4Color and Shape:SolidMolecular weight:360.494Pegcetacoplan acetate
<p>Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.</p>Color and Shape:Odour SolidTLR8 agonist 2 hydrochloride
CAS:<p>TLR8 agonist 2 hydrochloride: potent for human TLR8 (EC50 3 nM), weak for TLR7 (EC50 33.33 μM).</p>Formula:C16H22N8·xHClColor and Shape:SolidDihydromyristicin
CAS:<p>Dihydromyristicin, a plant flavonoid, curbs inflammation by inhibiting ROS and PI3K/Akt/NF-κB pathways.</p>Formula:C11H14O3Color and Shape:SolidMolecular weight:194.23D-NAME (hydrochloride)
CAS:<p>D-NAME, a less active NO synthase inhibitor enantiomer, has mild cardiovascular effects in rats; inactive in mouse nociception.</p>Formula:C7H16ClN5O4Color and Shape:SolidMolecular weight:269.69EB-TCIP
<p>EB-TCIP (BAK-04-212) is a bivalent molecule composed of AP1867 and BI-3812. It facilitates the reversible formation of a ternary complex between FKBPF36V and BCL6BTB, thereby recruiting FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, rapidly inducing expression of BCL6 target genes such as SOCS2 and CXCL11. EWS/FLI1 is a fusion transcription factor found in Ewing sarcoma. EB-TCIP is applicable for studying transcriptional dysregulation in cancer.</p>Color and Shape:Odour SolidCTP-NBD
CAS:<p>CTP-NBD is a cell-permeable, specific inhibitor of the NFκB peptide, which has been utilized in studies of colitis [1] [2].</p>Formula:C121H194N46O32Purity:98%Color and Shape:SolidMolecular weight:2805.12NLRP3-IN-12
<p>NLRP3-IN-12 inhibits NLRP3 inflammasome, curbing IL-1β release with 0.45 μM IC50, for inflammatory bowel disease research.</p>Formula:C27H32ClNO7Color and Shape:SolidMolecular weight:518NLRP3-IN-76
<p>NLRP3-IN-76 is an orally active NLRP3 inhibitor that suppresses the production of NO and reduces the mRNA levels of pro-inflammatory cytokines (iNOS, IL-6, IL-1β, and TNFα). It exerts anti-inflammatory effects by inhibiting the activation of the NLRP3 inflammasome and the NF-κB signaling pathway. Furthermore, NLRP3-IN-76 can ameliorate DSS-induced colitis and is applicable for studying inflammatory bowel disease (IBD).</p>Color and Shape:Odour SolidOICR11029
CAS:<p>OICR11029 is a potent probe for Bcl-6.</p>Formula:C26H25Cl2N7O5Color and Shape:SolidMolecular weight:586.427Amaroswerin
CAS:<p>Amaroswerin, a secoiridoid glucoside, has anti-inflammatory, antidiabetic, and other medicinal properties; it inhibits NO release at IC50 of 5.42 μg/mL.</p>Formula:C29H30O14Color and Shape:SolidMolecular weight:602.54AM-103 Free Acid
CAS:<p>AM-103 Free Acid is a bio-active chemical.</p>Formula:C36H39N3O4SColor and Shape:SolidMolecular weight:609.78ROS-ERS inducer 2
<p>ROS-ERS inducer 2 (Complex 3f) promotes the generation of intracellular ROS, affects mitochondrial function, facilitates the release of damage-associated molecular patterns (DAMPs), induces immunogenic cell death (ICD), and activates endoplasmic reticulum stress (ERS). It plays a significant role in anti-hepatocellular carcinoma research.</p>Formula:C24H23BrClF2N3PtColor and Shape:SolidMolecular weight:701.9Modakafusp alfa
CAS:<p>Modakafusp alfa (TAK-573): Humanized anti-CD38 monoclonal antibody with IFNα2b for multiple myeloma research.</p>Color and Shape:LiquidBCL6 PROTAC 1
CAS:<p>BCL6 PROTAC 1: Selective BCL6 degrader, IC50 8.8 µM, used in DLBCL research.</p>Formula:C45H52ClN9O12Color and Shape:SolidMolecular weight:946.4NLRP3-IN-14
CAS:<p>NLRP3-IN-14, potent selective NLRP3 inhibitor, KD 5.87μM; IC50 0.131μM for IL-1β; for inflammation research.</p>Formula:C27H28N2O4Color and Shape:SolidMolecular weight:444.52Methyl 3,4-Dihydroxyphenylacetate
CAS:<p>Methyl 3,4-Dihydroxyphenylacetate is an effective enterovirus 71 (EV71) inhibitor, suppressing EV71 replication in rhabdomyosarcoma (RD) cells, antiviral.</p>Formula:C9H10O4Purity:97.03%Color and Shape:SolidMolecular weight:182.17Bifarcept
CAS:<p>Bifarcept, a recombinant antibody targeting the interferon receptor type I (IFN-RI), enhances the serum half-life of IFN-β by facilitating its binding.</p>Color and Shape:LiquidPROTAC IRAK4 degrader-2
CAS:<p>PROTAC IRAK4 degrader-2 reduces IRAK4 in PBMCs with a DC50 of 36 nM and inhibits cytokines.</p>Formula:C57H68FN11O8SColor and Shape:SolidMolecular weight:1086.28L 012 sodium salt
CAS:<p>L 012 sodium salt: chemiluminescent probe for oxygen & nitrogen detection; identifies superoxides & Nox inhibitors.</p>Formula:C13H8ClN4NaO2Purity:98.08% - 98.70%Color and Shape:SolidMolecular weight:310.67Maritimetin
CAS:<p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>Formula:C15H10O6Color and Shape:SolidMolecular weight:286.24Dihydrorhodamine 6G
CAS:<p>DHR 6G, nonfluorescent reduced Rhodamine 6G, permeates cells, indicating ROS by oxidizing to fluorescent form in mitochondria.</p>Formula:C28H32N2O3Color and Shape:SolidMolecular weight:444.57UT-11
<p>UT-11: potent, brain-permeable mPGES-1 inhibitor. IC50: 0.10μM (human SK-N-AS), 2.00μM (murine BV2). Stops PGE2 production.</p>Formula:C17H19Cl2N3O2SColor and Shape:SolidMolecular weight:400.32Chitohexaose hexahydrochloride
CAS:<p>Chitohexaose hexahydrochloride, a TLR4-inhibiting chitosan derivative, blocks LPS-induced inflammation.</p>Formula:C36H74Cl6N6O25Color and Shape:SolidMolecular weight:1203.71Ibuprofen impurity 1
CAS:<p>Ibuprofen impurity 1: anti-inflammatory, inhibits COX-1/COX-2 with IC50s of 13 μM/370 μM.</p>Formula:C12H16O2Color and Shape:SolidMolecular weight:192.258Schiarisanrin A
CAS:<p>Schiarisanrin A (Kadsulignan J), a lignan, exhibits inhibitory activity on nitric oxide (NO) production, demonstrating an IC50 of 9.6 μM in BV-2 cells [1].</p>Formula:C27H32O8Purity:98%Color and Shape:SolidMolecular weight:484.54TLR7/8 agonist 12
<p>TLR7/8 agonist 12 (compound 9) is a human TLR7/8 agonist with EC50 values of 11 nM for hTLR7 and 150 nM for hTLR8, indicating its potential for immune modulation.</p>Formula:C29H38N6O3Color and Shape:SolidMolecular weight:518.65PROTAC IRAK4 degrader-6
CAS:<p>PROTAC IRAK4 degrader-6, potent, targets Cereblon to degrade IRAK4, detailed in US20190192668A1.</p>Formula:C42H41F3N12O8Color and Shape:SolidMolecular weight:898.861β-Aminoarteether
CAS:<p>β-Aminoarteether (SM934 free base), an orally active derivative of Artemisinin, serves a pivotal role in the research of inflammation and autoimmune disorders,</p>Formula:C17H29NO5Purity:96.09% - 97.02%Color and Shape:SolidMolecular weight:327.42Sericin
<p>Sericin is a globular protein isolated from silkworm cocoons. It has cognitive enhancement and pain-relieving properties. Additionally, Sericin serves as a cryoprotectant, potentially replacing fetal bovine serum or dimethyl sulfoxide (DMSO). It helps reduce oxidative stress and reactive oxygen species (ROS). Sericin aids in wound repair by promoting collagen production and exhibits activities such as antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, moisturizing, wound healing promotion, antibacterial, and antitumor effects.</p>Color and Shape:Odour SolidC3a (70-77)
CAS:<p>C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.</p>Formula:C35H61N13O10Purity:98%Color and Shape:SolidMolecular weight:823.9412-Oxo phytodienoic acid
CAS:<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Formula:C18H28O3Purity:98%Color and Shape:SolidMolecular weight:292.41Iromycin A
CAS:<p>Iromycin A: a bacterial metabolite inhibiting NOS III over NOS I, blocks NADH oxidation, IC50 = 0.461 µM.</p>Formula:C19H29NO2Color and Shape:SolidMolecular weight:303.44LC-MI-3
<p>LC-MI-3 is an orally active and potent PROTAC degrader of interleukin-1 receptor-associated kinase 4 (IRAK4), with a DC50 value of 47.3 nM. It effectively inhibits the activation of downstream NF-κB signaling. LC-MI-3 is applicable for research in both acute and chronic inflammatory skin conditions.</p>Formula:C39H36N8O8Molecular weight:744.26561ARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Color and Shape:SolidMolecular weight:120702.76Paneolilludinic acid
CAS:<p>Paneolilludinic acid from Cryptomarasmius aucubae fungus inhibits NO production.</p>Formula:C15H22O3Color and Shape:SolidMolecular weight:250.33MLT-231
<p>MLT-231: potent MALT1 Inhibitor, IC50=9 nM; blocks BCL10 cleavage, IC50=160 nM; exhibits antitumor efficacy in mouse ABC-DLBCL model.</p>Color and Shape:SolidHPK1-IN-57
<p>HPK1-IN-57 (Compound 10c) is an inhibitor of hematopoietic progenitor kinase 1 (HPK1) with an IC50 of 0.09 nM. It suppresses the activity of HPK1 kinase, inhibits the phosphorylation of downstream adaptor protein SLP76 (IC50 of 33.74 nM), and effectively induces the secretion of the T cell activation marker IL-2 (EC50 of 84.24 nM). HPK1-IN-57 holds promise for research in tumor immunotherapy.</p>Formula:C30H36F2N8O3Color and Shape:SolidMolecular weight:594.655Pepinh-MYD TFA
<p>Pepinh-MYD TFA is a MyD88 inhibitor that features domain sequences from MyD88TIR and a protein transduction sequence, allowing it to penetrate cell membranes. By disrupting MyD88-mediated TLR pathway signaling, it inhibits related immune responses. Pepinh-MYD TFA shows potential for investigating MyD88's role in viral infections.</p>Formula:C151H248N50O35S2·xC2HF3O2Color and Shape:SolidMolecular weight:3388.03 (free base)FAPI-46
CAS:<p>FAPI-46 is a radiotracer for fibroblast activation protein (FAP),conjugated with 68Ga or 177Lu tracer for FAP tumours in positron emission tomography (PET).</p>Formula:C41H57F2N11O9Color and Shape:SolidMolecular weight:885.965-LOX/NO-IN-1
<p>5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.</p>Formula:C22H18N6O4Color and Shape:SolidMolecular weight:430.42HSV-60mer sodium
<p>HSV-60mer sodium is a 60 bp double-stranded oligonucleotide that includes viral DNA motifs from the herpes simplex virus 1 (HSV-1) genome. Transfection of HSV-60mer effectively induces IFN-β in a manner dependent on STING, TBK1, and IFN regulatory factor 3 (IRF3).</p>Antibacterial agent 273
<p>Antibacterialagent 273 (Compound 15e) is an antimicrobial agent targeting bacterial cell membranes, effectively disrupting them with a MIC value of 4 μg/mL against Staphylococcus aureus. It causes the leakage of intracellular nucleic acids and proteins, inhibits bacterial metabolic activity, and induces the accumulation of reactive oxygen species (ROS) within bacteria. Antibacterialagent 273 is applicable in research on infections caused by Staphylococcus aureus.</p>Color and Shape:Odour SolidUNC9036
<p>UNC9036 is a PROTAC degrader of STING, with a DC50 value of 227 nM. The degradation of STING mediated by UNC9036 is dependent on the proteasomal VHL pathway.</p>Formula:C73H95N17O11SMolecular weight:1417.711773-(3-Methoxyphenyl)acrylic acid
CAS:<p>3-(3-Methoxyphenyl)acrylic acid can inhibit free radical generation, has antioxidant potential, and can be used in biochemical experiments and drug synthesis.</p>Formula:C10H10O3Purity:99.91%Color and Shape:SolidMolecular weight:178.19Septeremophilane E
<p>Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.</p>Formula:C21H26O5Color and Shape:SolidMolecular weight:358.433D-Monophosphoryl Lipid (12,16) free acid
CAS:<p>3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) free acid is a TLR agonist that serves as a vaccine adjuvant to boost the immunogenicity of vaccines.</p>Formula:C96H181N2O21PColor and Shape:SolidMolecular weight:1730.44NLRP3-IN-15
CAS:<p>NLRP3-IN-15: potent, selective NLRP3 inflammasome inhibitor; IC50 0.114 μM for IL-1β; for inflammation research.</p>Formula:C22H19NO4Color and Shape:SolidMolecular weight:361.39IRAK4-IN-24
<p>IRAK4-IN-24 (compound 16), a potent IRAK4 inhibitor, exhibits high clearance (Cl) and low oral bioavailability.</p>Formula:C19H19N5O3Purity:98%Color and Shape:SolidMolecular weight:365.392-Isopropyl-1H-imidazole
CAS:<p>2-Isopropyl-1H-imidazole is a weak inhibitor of NO synthase and can be used in related research in the field of life sciences.</p>Formula:C6H10N2Purity:99.71%Color and Shape:SolidMolecular weight:110.16(±)-Phrymarolin II
CAS:<p>(±)-Phrymarolin II is a promising class of inhibitors that targets the tobacco mosaic virus, representing a novel approach in plant virus suppression.</p>Formula:C23H22O10Color and Shape:SolidMolecular weight:458.419cGAMP diammonium
<p>cGAMP is a second messenger that triggers interferon production via STING activation upon detecting cytosolic DNA.</p>Formula:C20H30N12O13P2Color and Shape:SolidMolecular weight:708.47FSL-1
CAS:<p>TLR2/6 agonist, may bind TLR10. Activates NF-κB, triggers IL-8, IL-1β, CCL20, TNF-α. Boosts IFNγ-induced CXCL10 in melanoma.</p>Formula:C84H140N14O18SPurity:98%Color and Shape:SolidMolecular weight:1666.16Inflexuside A
CAS:<p>Inflexuside A, an abietane diterpenoid from Isodon inflexus, and Inflexuside B inhibit NO in LPS-stimulated RAW264.7 cells.</p>Formula:C26H42O9Color and Shape:SolidMolecular weight:498.61JPE-1375
CAS:<p>JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.</p>Formula:C49H63FN10O9Color and Shape:SolidMolecular weight:955.08Anti-Mouse CD4 Antibody (2G5.D)
<p>Anti-Mouse CD4 Antibody (2G5.D) is an anti-mouse CD4 antibody widely used in research and experiments in the field of life sciences.</p>Purity:>95% Determined by SDS-PAGE - >95% Determined by SDS-PAGEColor and Shape:Odour LiquidCafestol palmitate
CAS:<p>Cafestol palmitate is an active compound found in green coffee beans. It can enhance the activity of glutathione S-transferase (GST) in mice and also exhibits weak COX-2 inhibitory activity.</p>Formula:C36H58O4Color and Shape:SolidMolecular weight:554.843Nω-allyl-L-arginine
CAS:<p>Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS), efficiently inactivating nNOS in a time-dependent</p>Formula:C9H18N4O2Color and Shape:SolidMolecular weight:214.26Vensobafusp alfa
CAS:<p>Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.</p>Color and Shape:LiquidTuparstobart
CAS:<p>Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on</p>Color and Shape:LiquidTAB-004
<p>TAB-004 is a human monoclonal antibody targeting MUC1. It specifically identifies the tMUC1 present in all major subtypes of breast cancer without affecting normal breast epithelial cells. Additionally, TAB-004 is applicable for research on triple-negative breast cancer (TNBC).</p>Color and Shape:Odour LiquidSTING agonist-29
CAS:<p>CF511: non-nucleotide, small-molecule STING activator; fights SARS-CoV variants.</p>Formula:C38H44N14O6Color and Shape:SolidMolecular weight:792.85Anti-inflammatory agent 78
<p>Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. It effectively inhibits PGE2, PGE1, COX-2, and COX-1. Additionally, Anti-inflammatory agent 78 suppresses the release of NO in LPS-stimulated RAW 264.7 cell lines.</p>Formula:C19H14ClNO4Molecular weight:355.06114MC-ND-18
<p>MC-ND-18 is an ATTEC degrader that facilitates the degradation of NLRP3 via autophagy, exhibiting a DC50 of 125.5 nM in THP-1 cells. It is composed of an NLRP3 ligand, a linker, and an LC3 ligand.</p>Formula:C42H42Br2IN3O9SMolecular weight:1049.00532AR20.5
<p>AR20.5 is a human monoclonal antibody targeting MUC1. It enhances the number of activated CD8 T cells, CD3+CD4−CD8− (DN) T cells, and mature dendritic cells in mice with pancreatic tumors. AR20.5 is applicable for research into anti-pancreatic cancer immunity.</p>Color and Shape:Odour LiquidSTING ligand-4
<p>STING ligand-4 (Compound 2) is a nitro-free covalent STING inhibitor with an IC50 of less than 0.2 μM. It can be utilized in the synthesis of PROTACSTINGdegrader-4.</p>Formula:C18H18Cl2N6OColor and Shape:SolidMolecular weight:404.09191ABTIM3-hum11
<p>ABTIM3-hum11 is a humanized anti-TIM3 blood-brain barrier shuttling monoclonal antibody.</p>Purity:94% (SDS-PAGE); 98.2% (SEC-HPLC) - 94% (SDS-PAGE); 98.2% (SEC-HPLC)Color and Shape:Odour LiquidGalectin-3-IN-5
<p>Galectin-3-IN-5 (Compound 20) is an orally active inhibitor of galectin-3 (Gal-3), exhibiting an IC50 value of 9.2 nM against hGal-3.</p>Formula:C24H19BrClF5N6O4SColor and Shape:SoildMolecular weight:697.86CTT2274
<p>CTT2274 is a prodrug of MMAE. It consists of a prostate-specific membrane antigen (PSMA) binding scaffold, a biphenyl motif, a pH-sensitive phosphoramidate linker, and an MMAE payload. CTT2274 selectively targets and binds to PSMA to deliver MMAE and has the capability to inhibit prostate cancer.</p>Formula:C119H159N17O33P2Color and Shape:SolidMolecular weight:2417.587-Deoxy-trans-dihydronarciclasine
CAS:<p>7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-</p>Formula:C14H15NO6Color and Shape:SolidMolecular weight:293.275-LOX/sEH-IN-1
<p>Compound 8o (5-LOX/sEH-IN-1) is a dual inhibitor with cardioprotective properties, targeting both 5-LOX and sEH with IC50 values of 3.05 μM and 2.20 nM respectively. It also inhibits the activity of COX-2 (IC50=10.50 μM). Possessing analgesic and anti-inflammatory properties, 5-LOX/sEH-IN-1 reduces ulcerogenicity, making it a potential candidate for developing anti-inflammatory agents with fewer gastrointestinal and cardiovascular side effects.</p>Color and Shape:Odour SolidSARS-CoV-2 Mpro-IN-41
<p>SARS-CoV-2 Mpro-IN-41 (Compound 7e) is an orally active inhibitor targeting COX-2 and SARS-CoV-2 Mpro, with respective IC50 values of 9.66 μM and 13.24 μM. It also demonstrates inhibitory activity against COX-1 (IC50: 46.11 μM). This compound significantly suppresses the expression of inflammation-related cytokines such as TNF-α, IL-6, and IL-1β, exhibiting anti-inflammatory properties. By selectively inhibiting COX-2 and SARS-CoV-2 Mpro, SARS-CoV-2 Mpro-IN-41 exerts both anti-inflammatory and antiviral effects, making it a potential candidate for research in inflammation and COVID-19 treatment.</p>Formula:C27H23ClN4O3SColor and Shape:SolidMolecular weight:518.11794Prezalumab
CAS:<p>Prezalumab (AMG 557) is a human IgG2 monoclonal antibody against ICOSL and BAFF.</p>Purity:> 95%Color and Shape:LiquidMolecular weight:145.42 kDaKeap1-Nrf2-IN-9
CAS:<p>Keap1-Nrf2-IN-9 inhibits Keap1-Nrf2 PPI with 0.575 µM IC50, boosts Nrf2 genes, non-toxic in ARPE19 cells.</p>Formula:C31H30N2O11S2Color and Shape:SolidMolecular weight:670.71
