Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(940 products)
- ACK(1 products)
- AChR(574 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,942 products)
- BACE(36 products)
- Beta Amyloid(204 products)
- CaMK(68 products)
- Cyclooxygenase (COX) Inhibitors(562 products)
- Dopamine Receptor(407 products)
- GABA Receptor(336 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(358 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(28 products)
- OX Receptor(40 products)
- Opioid Receptor(296 products)
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Found 5400 products of "Neuroscience"
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FITC-β-Ala-Amyloid β-Protein (1-42)
CAS:<p>FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.</p>Formula:C227H327N57O66S2Molecular weight:4971.34251(+)-OSU 6162
CAS:<p>(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.</p>Formula:C15H23NO2SPurity:98.19%Color and Shape:SoildMolecular weight:281.41Rubrofusarin triglucoside
CAS:<p>Rubrofusarin triglucoside, a glycoside from Cassia obtusifolia seeds, inhibits hMAO-A with an IC50 of 85.5 μM.</p>Formula:C33H42O20Color and Shape:SolidMolecular weight:758.679AChE-IN-49
<p>AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.</p>Formula:C31H28BrClN2O3Molecular weight:590.09718NPS ALX Compound 4a hydrochloride(1:1)
<p>NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.</p>Formula:C25H26ClN3O2SPurity:99.84%Color and Shape:SoildMolecular weight:468.01Galanin (1-15) (porcine, rat)
CAS:<p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>Formula:C72H105N19O20Purity:98%Color and Shape:SolidMolecular weight:1556.72AChE/BChE-IN-26
<p>AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM for eeAChE and 4.11 μM for eqBChE. This compound possesses antioxidant properties and is applicable in research related to diseases such as Alzheimer's.</p>Color and Shape:Odour Solid1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:<p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>Formula:C10H12N2O2SPurity:99.96%Color and Shape:SoildMolecular weight:224.28β-Amyloid (33-40)
CAS:<p>β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.</p>Formula:C32H58N8O9SPurity:98%Color and Shape:SolidMolecular weight:730.92Fasciculic acid B
CAS:<p>Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.</p>Formula:C36H60O9Purity:98%Color and Shape:SolidMolecular weight:636.86Biperiden Hydrochloride
CAS:<p>Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.</p>Formula:C21H30ClNOPurity:98%Color and Shape:SolidMolecular weight:347.923-Aminopropylphosphonic Acid
CAS:<p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>Formula:C3H10NO3PPurity:99.84%Color and Shape:Light Yellow LiquidMolecular weight:139.09Lanuginosine
CAS:<p>Lanuginosine, an aporphine alkaloid, exhibits cytotoxicity against U251.</p>Formula:C18H11NO4Color and Shape:SolidMolecular weight:305.28AChE-IN-60
<p>AChE-IN-60 (compound 6k) is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 27 nM and 43 nM, respectively. It also inhibits monoamine oxidase MAO-A and MAO-B, with IC50 values of 353 nM and 716 nM, respectively.</p>Formula:C24H29N3O4S3Molecular weight:519.13202Neuronal Signaling Compound Library
<p>A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>Color and Shape:Odour SolidAlosetron
CAS:<p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>Formula:C17H18N4OPurity:98%Color and Shape:Crystalline PowderMolecular weight:294.36(S,S)-BMS-984923
CAS:<p>(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.</p>Formula:C22H15ClN2O2Color and Shape:SolidMolecular weight:374.82P-gb-IN-1
CAS:<p>P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow.</p>Formula:C30H28N2O6Purity:99.58%Color and Shape:SoildMolecular weight:512.55CDD0102 HCl
CAS:<p>CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.</p>Formula:C8H13ClN4OPurity:99.7%Color and Shape:SoildMolecular weight:216.67Flupyradifurone
CAS:<p>Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.</p>Formula:C12H11ClF2N2O2Purity:99.83%Color and Shape:SolidMolecular weight:288.68Fabesetron
CAS:<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Formula:C18H19N3OColor and Shape:SolidMolecular weight:293.37Xaliproden
CAS:<p>Xaliproden is a biochemical.</p>Formula:C24H22F3NColor and Shape:SolidMolecular weight:381.43ACG548B
CAS:<p>ACG548B inhibits AChE/BChE with IC50s of 1.78/0.496 μM; favors AChE over BChE/ChoK.</p>Formula:C38H34Br2Cl2N4Color and Shape:SolidMolecular weight:777.43Polyglutamine binding peptide 1
CAS:<p>Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ). It effectively inhibits polyQ protein aggregation in vitro and prevents polyQ-induced cell death in cell cultures.</p>Formula:C72H90N16O16Color and Shape:SolidMolecular weight:1435.58Lu AE51090
CAS:<p>Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.</p>Formula:C24H29N3O3Purity:99.57%Color and Shape:SolidMolecular weight:407.51CUR-IPA
<p>CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.</p>Formula:C43H38N2O8Color and Shape:SolidMolecular weight:710.77TIM-098a
<p>TIM-098a is a selective AAK1 inhibitor with an IC50 of 0.24 µM. It does not inhibit CaMKK isoforms. By inhibiting AAK1 kinase activity, TIM-098a disrupts AAK1-regulated endocytosis.</p>Formula:C18H11N3O2Molecular weight:301.08513Sodium Channel Targeted Library
<p>A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;</p>Color and Shape:Odour SolidDCCCyb
CAS:<p>DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.</p>Formula:C22H29Cl2NO3SPurity:98%Color and Shape:SolidMolecular weight:458.44Coumarinic acid
CAS:<p>Coumarinic acid serves as a brain-penetrating inhibitor of AChE (acetylcholinesterase) and β-amyloid, with applications in anti-Alzheimer's drug research [1].</p>Formula:C9H8O3Color and Shape:SolidMolecular weight:164.16Methoxy-X04
CAS:<p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>Formula:C23H20O3Purity:98.96%Color and Shape:SolidMolecular weight:344.4PSEN1-IN-2
<p>PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.</p>Formula:C20H18ClFN2O3SColor and Shape:SolidMolecular weight:420.888-Aminoadenine
CAS:<p>8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.</p>Formula:C5H6N6Purity:99.82%Color and Shape:SolidMolecular weight:150.14COX-2-IN-34
CAS:<p>COX-2-IN-34 is a selective, orally potent COX-2 inhibitor that shows anti-inflammatory activity without gastric ulcer toxicity during experiments in mice.</p>Formula:C13H11NO4Purity:98.08%Color and Shape:SoildMolecular weight:245.23Tetrahydro-β-carboline
CAS:<p>Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C11H12N2Purity:96.31%Color and Shape:Tan SolidMolecular weight:172.2264Isograndifoliol
CAS:<p>Isograndifoliol: BChE inhibitor (IC50=0.9μM), weaker AChE inhibitor (IC50=342.9μM), with vasorelaxant and anti-tumor properties.</p>Formula:C19H26O3Color and Shape:SolidMolecular weight:302.41Nipecotic acid
CAS:<p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C6H11NO2Color and Shape:Off-White To Pale Yellow-Beige PowderMolecular weight:129.16PD10
<p>PD10 is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), exhibiting inhibitory potency at human AChE (hAChE IC50: 0.56 μM),</p>Formula:C23H21BrN2O4Color and Shape:SolidMolecular weight:469.33AChE-IN-27
CAS:<p>AChE-IN-27 is a small molecule used for high-throughput assays.</p>Formula:C20H14N2O3Purity:98.54%Color and Shape:SolidMolecular weight:330.34Velnacrine
CAS:<p>Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.</p>Formula:C13H14N2OPurity:99.83%Color and Shape:SolidMolecular weight:214.26EB-42486
CAS:<p>EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.</p>Formula:C22H22N8OPurity:99.53%Color and Shape:SolidMolecular weight:414.46SIB 1553A
CAS:<p>SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.</p>Formula:C13H19NOSPurity:99.79%Color and Shape:SoildMolecular weight:237.36(S)-UFR2709 hydrochloride
CAS:<p>(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety & alcohol intake in rats, studies nicotine addiction.</p>Formula:C13H18ClNO2Purity:98.94%Color and Shape:SolidMolecular weight:255.74NMDAR antagonist 2
<p>NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage.</p>Formula:C17H20ClNOColor and Shape:SolidMolecular weight:289.8AChE/MAO-B-IN-7
<p>AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.</p>Formula:C22H21N3O3Color and Shape:SolidMolecular weight:375.42Methylatropine (nitrate)
CAS:<p>Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.</p>Formula:C18H26N2O6Color and Shape:SolidMolecular weight:366.414(E/Z)-Sivopixant
CAS:<p>(E/Z)-Sivopixant ((E/Z)-S-600918)is a potent P2X3 receptor antagonist, IC50 = 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research.</p>Formula:C25H22ClN5O5Purity:99.82%Color and Shape:SolidMolecular weight:507.93CALP2
CAS:<p>CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.</p>Formula:C68H104N14O13SPurity:98%Color and Shape:SolidMolecular weight:1357.72Chrysophanol-1-O-β-gentiobioside
CAS:<p>Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside obtained from the seeds of Cassia obtusifolia, exhibits targeted inhibition of hMAO-A isozyme</p>Formula:C27H30O14Color and Shape:SolidMolecular weight:578.52AChE-IN-70
<p>AChE-IN-70 (compound 4) is an acetylcholinesterase inhibitor. It exhibits larvicidal activity against mosquito larvae (Culex pipiens L.), making it useful for mosquito control research.</p>Color and Shape:Odour SolidAChE/BChE-IN-14
<p>AChE/BChE-IN-14 (compound 13), a benzylisoquinoline alkaloid extracted from Fissistigma polyanthum roots, demonstrates inhibitory effects on both</p>Formula:C19H23NO3Color and Shape:SolidMolecular weight:313.39GSK-3β inhibitor 27
<p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>Formula:C16H17ClN4O2Color and Shape:SolidMolecular weight:332.79hAChE-IN-6
<p>hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM.</p>Color and Shape:Odour SolidDesfesoterodine
CAS:<p>Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.</p>Formula:C22H31NO2Purity:99.77%Color and Shape:SolidMolecular weight:341.49CZC-54252 hydrochloride
CAS:<p>CZC-54252 hydrochloride: selective LRRK2 inhibitor; IC50 = 1.85/1.28 nM (wild-type/G2019S); neuroprotective; EC50 = 1 nM for G2019S injury.</p>Formula:C22H26Cl2N6O4SPurity:98.21%Color and Shape:SolidMolecular weight:541.45AChE-IN-45
<p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>Color and Shape:Odour SolidXenopus orexin B
CAS:<p>Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].</p>Formula:C130H219N45O40S2Color and Shape:SolidMolecular weight:3116.54BChE-IN-40
<p>BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. It demonstrates significant anti-inflammatory effects, with an IC50 of 4.55 μM in inhibiting nitric oxide production. Additionally, BChE-IN-40 exhibits excellent permeability across the blood-brain barrier.</p>Formula:C28H30N2O7Color and Shape:SolidMolecular weight:506.2053Litoxetine HCl
<p>Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.</p>Formula:C16H20ClNOPurity:99.56% - 99.75%Color and Shape:SoildMolecular weight:277.79β-Amyloid (1-11)
CAS:<p>Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid</p>Formula:C56H76N16O22Purity:98%Color and Shape:SolidMolecular weight:1325.3LY 293284
CAS:<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Formula:C19H26N2OColor and Shape:SolidMolecular weight:298.42JH-XII-03-02
CAS:<p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>Formula:C43H51N9O10Purity:98%Color and Shape:SolidMolecular weight:853.92Calmodulin Binding Peptide 1
CAS:<p>Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.</p>Formula:C231H373N69O70S2Purity:98%Color and Shape:SolidMolecular weight:5301.1AChE-IN-86
<p>AChE-IN-86 (Compound 6f) is an inhibitor of acetylcholinesterase (AChE) with an IC50 value of 25.33 μg/mL. This compound exerts its inhibitory effects by forming hydrogen bonds, π-π, and π-alkyl interactions with amino acid residues at the key catalytic site of AChE. AChE-IN-86 can be utilized in Alzheimer's disease research.</p>Formula:C28H27N3O6SColor and Shape:SolidMolecular weight:533.595C18 L-erythro Ceramide (d18:1/18:0)
CAS:<p>C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.</p>Formula:C36H71NO3Color and Shape:SolidMolecular weight:565.95hAChE-IN-5
<p>hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency with</p>Purity:98%Color and Shape:Odour SolidTC-2559 difumarate
CAS:<p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>Formula:C20H26N2O9Color and Shape:SolidMolecular weight:438.43BTMPS
CAS:<p>BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.</p>Formula:C28H52N2O4Purity:98.1%Color and Shape:SolidMolecular weight:480.721,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Formula:C10H18OPurity:97.44% - 97.44%Color and Shape:SolidMolecular weight:154.25epi-Aszonalenin A
CAS:<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48LY-53857 free base
CAS:<p>LY-53857 free base is a bioactive chemical.</p>Formula:C23H32N2O3Color and Shape:SolidMolecular weight:384.51β-Amyloid (1-40)
CAS:<p>Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.</p>Formula:C194H295N53O58SPurity:98%Color and Shape:SolidMolecular weight:4329.82TZ4M
<p>TZ4M, a 2,4-thiazolidinedione (TZD)-based anti-ADV agent, exhibits neuroprotective effects and acetylcholinesterase (AChE) inhibition in human plasma.</p>Formula:C19H15NO4SColor and Shape:SolidMolecular weight:353.39BChE-IN-12
CAS:<p>BChE-IN-12, non-competitive BChE inhibitor from Bletilla striata, IC50=2.3μM; potential Alzheimer’s research.</p>Formula:C31H30O5Color and Shape:SolidMolecular weight:482.57Neuroprotective Compound Library
<p>A unique collection of xnum bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);</p>Color and Shape:Odour SolidDicloromezotiaz
CAS:<p>Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.</p>Formula:C19H12Cl3N3O2SColor and Shape:SolidMolecular weight:452.74AChE/BChE-IN-11
CAS:<p>AChE/BChE-IN-11, natural from artichoke leaves, inhibits AChE and BChE (IC50: 70/71 μM) for Alzheimer's research.</p>Formula:C21H22O12Color and Shape:SolidMolecular weight:466.39SC-53116
CAS:<p>SC-53116 HCl can increase the production of serotonin in central nervous system tissues and is a psychoactive agent.</p>Formula:C16H22ClN3O2Color and Shape:SolidMolecular weight:323.828-hydroxy Amoxapine
CAS:<p>8-hydroxy Amoxapine is a metabolite of the tetracyclic antidepressant amoxapine .1,2</p>Formula:C17H16ClN3O2Color and Shape:SolidMolecular weight:329.78β-Amyloid (1-38), mouse, rat
CAS:<p>β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.</p>Color and Shape:Solidβ-Amyloid (18-28)
CAS:<p>Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.</p>Formula:C55H81N13O18Purity:98%Color and Shape:SolidMolecular weight:1212.31(Met(O2)35)-Amyloid β-Protein (1-42)
<p>(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .</p>Formula:C203H311N55O62SColor and Shape:SolidMolecular weight:4546.04AChE-IN-35
<p>AChE-IN-35 (compound 5g) serves as an acetylcholinesterase inhibitor, exhibiting an inhibitory concentration 50 (IC50) value of 5.88 μM [1].</p>Formula:C20H16N8O5Color and Shape:SolidMolecular weight:448.39AChE/Aβ-IN-6
<p>BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.</p>Color and Shape:Odour SolidMuscarine
CAS:<p>Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>Formula:C9H20NO2Purity:98%Color and Shape:SolidMolecular weight:174.26(S)-AMPA HCl
<p>(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.</p>Formula:C7H11ClN2O4Purity:99.18%Color and Shape:SolidMolecular weight:222.63Flufiprole
CAS:<p>Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.</p>Formula:C16H10Cl2F6N4OSColor and Shape:SolidMolecular weight:491.24FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
<p>FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.</p>Formula:C227H330N58O66S2Color and Shape:SolidMolecular weight:4991.53(Met(O)35)-Amyloid β-Protein (1-42)
<p>(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of</p>Formula:C203H311N55O61SColor and Shape:SolidMolecular weight:4530.04Lycoramine hydrobromide
CAS:<p>Lycoramine is a natural alkaloid isolated from Lycoris chinensis.</p>Formula:C17H24BrNO3Color and Shape:SolidMolecular weight:370.28mcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Formula:C71H99N17O16Color and Shape:SolidMolecular weight:1446.65PD25
<p>PD25, an inhibitor of both AChE and BuChE, demonstrates inhibitory constants of hAChE IC50: 1.58 μM, eeAChE IC50: 1.63 μM, and eqBuChE IC50: 2.39 μM.</p>Formula:C25H24N2O4Color and Shape:SolidMolecular weight:416.47PD07
<p>PD07 is an orally active acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 of 0.29 μM against human AChE, and demonstrates inhibition of cholinesterases</p>Formula:C23H21ClN2O4Color and Shape:SolidMolecular weight:424.88BI 1181181 MZ
<p>BI 1181181 MZ is a potent and selective BACE1 inhibitor. BI 1181181 MZ is applicable to Alzheimer's disease research.</p>Formula:C31H37FN4O5Color and Shape:SolidMolecular weight:564.2748Biotin-β-Amyloid (1-42), human TFA
<p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>Formula:C215H326F3N57O64S2Color and Shape:SolidMolecular weight:4854.36(R)-(+)-Anatabine
CAS:<p>(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.</p>Formula:C10H12N2Purity:98%Color and Shape:SolidMolecular weight:160.22OM99-2 TFA
CAS:<p>OM99-2 TFA, an 8-residue inhibitor of brain memapsin 2, has a Ki of 9.58 nM, showing promise in Alzheimer's research.</p>Formula:C43H65F3N8O16Color and Shape:SolidMolecular weight:1007.028Cytidine 5′-diphosphoethanolamine
CAS:<p>Cytidine 5′-diphosphoethanolamine, a key intermediate in phosphatidylethanolamine synthesis, also serves as a stimulant of Ach synthesis [1].</p>Formula:C11H20N4O11P2Color and Shape:SolidMolecular weight:446.24BuChE-IN-8
<p>BuChE-IN-8 (compound 19c), a butyrylcholinesterase (BuChE) inhibitor, exhibits an IC50 value of 559 nM and concurrently inhibits human β-secretase (BACE1) and</p>Formula:C28H33ClN4O2SColor and Shape:SolidMolecular weight:525.11Peptide 401
CAS:<p>Peptide 401: AMP from bee/wasp venom, triggers histamine release, reduces paw swelling.</p>Formula:C110H192N40O24S4Purity:98%Color and Shape:SolidMolecular weight:2587.22BSB
CAS:<p>BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.</p>Formula:C24H17BrO6Purity:95.53%Color and Shape:SolidMolecular weight:481.29Acetyl-Tau Peptide (273-284) amide
CAS:<p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>Formula:C64H116N18O17Color and Shape:SolidMolecular weight:1409.72ZL-1101
<p>ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.</p>Color and Shape:Odour LiquidSyntide 2 TFA
<p>Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.</p>Formula:C70H123N20F3O20Color and Shape:SolidMolecular weight:1621.84(Glu20)-Amyloid β-Protein (1-42)
CAS:<p>(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.</p>Formula:C199H309N55O62SColor and Shape:SolidMolecular weight:4495.98Anti-Amyloid β Antibody (scFv59)
<p>Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>Color and Shape:Odour Liquid(Rac)-Sclerone
CAS:<p>(Rac)-Sclerone, a natural product isolated from the green husk of Carya illinoinensis, exhibits significant AChE inhibition activity with an IC50 value of 192.</p>Formula:C10H10O3Color and Shape:SolidMolecular weight:178.18Mosapride citrate dihydrate
CAS:<p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>Formula:C27H35ClFN3O11Purity:98%Color and Shape:SolidMolecular weight:632.04BMY-14802
CAS:<p>BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.</p>Formula:C18H22F2N4OPurity:99.84%Color and Shape:SoildMolecular weight:348.39TAT-CN21 (scrambled)
<p>TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).</p>Color and Shape:Odour SolidCianopramine hydrochloride
CAS:<p>Cianopramine hydrochloride is a bio-active chemical.</p>Formula:C20H24ClN3Color and Shape:SolidMolecular weight:341.88pCPA methyl ester hydrochloride
CAS:<p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>Formula:C10H13Cl2NO2Purity:99.73% - 99.88%Color and Shape:SolidMolecular weight:250.12MAO-IN-6
<p>MAO-IN-6 (Compound 3f) is a reversible MAO-B inhibitor that can cross the blood-brain barrier, with an IC50 value of 0.09 μM. It also shows inhibitory activity against AChE and BChE, with IC50 values of 4.48 μM and 17.03 μM, respectively. MAO-IN-6 exhibits low cytotoxicity and is applicable in Alzheimer's disease research.</p>Formula:C22H14F3NO2Color and Shape:SolidMolecular weight:381.35AChE-IN-46
<p>AChE-IN-46 (compound 4), a β-cyclocostunolide, functions as an acetylcholinesterase (AChE) inhibitor [1].</p>Formula:C15H22O2Color and Shape:SolidMolecular weight:234.33Heliosupine
<p>Heliosupine is a useful organic compound for research related to life sciences and the catalog number is T125038.</p>Formula:C20H31NO7Color and Shape:SolidMolecular weight:397.468(Rac)-Norcisapride
CAS:<p>Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.</p>Formula:C14H20ClN3O3Purity:99.32%Color and Shape:SoildMolecular weight:313.78Dehydro Aripiprazole (hydrochloride)
CAS:<p>Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.</p>Formula:C23H26Cl3N3O2Color and Shape:SolidMolecular weight:482.83AChE-IN-34
<p>AChE-IN-34 (compound 5l) is a potent, selective AChE inhibitor exhibiting an IC50 of 3.98 µM and negligible BChE inhibition.</p>Formula:C19H14N8O6Color and Shape:SolidMolecular weight:450.36Anticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Formula:C22H24N4O2Color and Shape:SolidMolecular weight:376.45MIDD0301
CAS:<p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>Formula:C19H13BrFN3O2Purity:98%Color and Shape:SolidMolecular weight:414.23AChE-IN-39
<p>AChE-IN-39 (Compound 7c), with an IC50 value of 0.058 μM, is an acetylcholinesterase (AChE) inhibitor known for its DPPH scavenging activity and potential to</p>Formula:C19H15NO3Color and Shape:SolidMolecular weight:305.335-HT1AR/5-HT6R ligand-1
<p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>Formula:C25H29ClN4O2SColor and Shape:SolidMolecular weight:485.04AChE/BuChE/MAO-B-IN-2
<p>AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM,</p>Formula:C19H18FNO3Color and Shape:SolidMolecular weight:327.35Aβ-IN-7
<p>Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomers</p>Formula:C14H10N2SColor and Shape:SolidMolecular weight:238.31LY 344864 racemate
CAS:<p>LY 344864 racemate is a 5-HT1F receptor agonist.</p>Formula:C21H22FN3OPurity:99.75%Color and Shape:SoildMolecular weight:351.42Pozanicline hydrochloride
<p>Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.</p>Formula:C11H17ClN2OPurity:97.13% - 99.81%Color and Shape:SolidMolecular weight:228.72CVN417
<p>CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion.</p>Color and Shape:Odour SolidRo60-0175
CAS:<p>Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.</p>Formula:C11H12ClFN2Purity:97.09%Color and Shape:SolidMolecular weight:226.68AChE-IN-29
<p>AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric</p>Formula:C18H19BrN2O2Color and Shape:SolidMolecular weight:375.26(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:<p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>Formula:C22H32ClNO2Color and Shape:SolidMolecular weight:377.95(-)-Eseroline fumarate
CAS:<p>(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.</p>Formula:C17H22N2O5Color and Shape:SolidMolecular weight:334.37BChE-IN-21
<p>BChE-IN-21, a potent inhibitor of butyrylcholinesterase (BChE), exhibits an inhibition constant (IC50) of 0.14 ± 0.02 μM, indicating promise for research in</p>Color and Shape:Odour SolidAChE/BChE-IN-15
<p>AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (</p>Formula:C29H30N6O3Color and Shape:SolidMolecular weight:510.59Notch 1 TFA
<p>Notch 1 TFA encodes a member of the NOTCH family of proteins.</p>Formula:C64H98N15F3O25S3Purity:98%Color and Shape:SolidMolecular weight:1614.81Xanthohumol I
<p>Xanthohumol I is a natural product that can be used as a reference standard.</p>Formula:C21H22O6Color and Shape:SolidMolecular weight:370.401Lisuride maleate
CAS:<p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>Formula:C24H30N4O5Purity:99.85%Color and Shape:SolidMolecular weight:454.52nAChR modulator-1
CAS:<p>nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Formula:C12H8ClN3O2Color and Shape:SolidMolecular weight:261.66Echimidine N-oxide
CAS:<p>Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.</p>Formula:C20H31NO8Color and Shape:SolidMolecular weight:413.467LY3020371
CAS:<p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>Formula:C15H15F2NO5SColor and Shape:SolidMolecular weight:359.34DDC 2′,3′-O-disulfate
<p>DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].</p>Formula:C17H16O11S2Color and Shape:SolidMolecular weight:460.43(±)-LY367385
CAS:<p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>Formula:C10H11NO4Color and Shape:SolidMolecular weight:209.2012'-O-Succinyl-cAMP
CAS:<p>2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2</p>Formula:C14H16N5O9PColor and Shape:SolidMolecular weight:429.282Trontinemab
CAS:<p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>Purity:96.77% - 99%Color and Shape:LiquidBuChE-IN-16
<p>BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.</p>Formula:C16H22N2O3Color and Shape:SolidMolecular weight:290.36α5-GABAA receptor modulator 1
<p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>Formula:C21H20FN3O4Color and Shape:SolidMolecular weight:397.4Multitarget AD inhibitor-1
CAS:<p>Multitarget AD inhibitor-1: reversible, selective BuChE blocker, inhibits β-secretase and amyloid/tau aggregation, promising for Alzheimer's research.</p>Formula:C29H38N2OColor and Shape:SolidMolecular weight:430.636Anticonvulsant agent 8
<p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>Formula:C15H11N5OColor and Shape:SolidMolecular weight:277.28Rasagiline 13C3 mesylate racemic
CAS:<p>Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.</p>Formula:C13H17NO3SPurity:98%Color and Shape:SolidMolecular weight:270.32N-Ethyl-N-(3-pyridylmethyl)amine
CAS:<p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>Formula:C8H12N2Purity:99.65%Color and Shape:SolidMolecular weight:136.19VVZ-149
<p>VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.</p>Color and Shape:SolidTIP 39, Tuberoinfundibular Neuropeptide
CAS:<p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>Formula:C202H325N61O54SPurity:98%Color and Shape:SolidMolecular weight:4504.2Epiboxidine hydrochloride
CAS:<p>Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.</p>Formula:C10H15ClN2OColor and Shape:SolidMolecular weight:214.69Atracurium
CAS:<p>Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.</p>Formula:C53H72N2O122Color and Shape:SolidMolecular weight:929.14OXA(17-33)
CAS:<p>Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.</p>Formula:C79H125N23O22Purity:98%Color and Shape:SolidMolecular weight:1749RA306
<p>RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.</p>Color and Shape:Odour SolidSulamserod
CAS:<p>Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related</p>Formula:C19H28ClN3O5SPurity:98.76%Color and Shape:SolidMolecular weight:445.96β-Secretase Inhibitor II
CAS:<p>β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase.</p>Formula:C25H39N3O5Color and Shape:SolidMolecular weight:461.59Atagabalin
CAS:<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Formula:C10H19NO2Color and Shape:SolidMolecular weight:185.26Moxonidine hydrochloride
CAS:<p>Moxonidine Hydrochloride: selective I1 imidazoline receptor agonist, stronger than α2-AR; lowers blood pressure; central action.</p>Formula:C9H13Cl2N5OColor and Shape:SolidMolecular weight:278.14Alosetron-d3
CAS:<p>Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.</p>Formula:C17H18N4OPurity:98%Color and Shape:SolidMolecular weight:297.37K1833
<p>K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$.</p>Color and Shape:Odour Solidβ-Amyloid (12-20)
CAS:<p>β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has</p>Formula:C57H83N15O11Purity:98%Color and Shape:SolidMolecular weight:1154.36Nitrazolam
CAS:<p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>Formula:C17H13N5O2Color and Shape:SolidMolecular weight:319.32CHF-5022
CAS:<p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>Formula:C17H12F4O2Color and Shape:SolidMolecular weight:324.27Fasciculic acid A
CAS:<p>Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>Formula:C36H60O8Color and Shape:SolidMolecular weight:620.868LBG20304
<p>LBG20304 (compound 2s) serves as a ligand for the homologous GluK5 receptor, demonstrating an IC50 of 432 nM and exhibiting over 40-fold selectivity against the GluK1-3 isoforms. At concentrations below 10 μM, LBG20304 shows neither agonistic nor antagonistic effects on heterologous GluK2/5 receptors. However, at concentrations above 10 μM, it displays minimal agonist activity in neuronal slices (rat).</p>Formula:C19H18N4O5Color and Shape:SolidMolecular weight:382.37AChE-IN-37
<p>AChE-IN-37 (compound A2) is an acetylcholinesterase inhibitor with an inhibitory concentration (IC50) of 0.23 µM.</p>Formula:C21H12ClNO7SColor and Shape:SolidMolecular weight:457.84CGP 35348
CAS:<p>CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。</p>Formula:C8H20NO4PPurity:≥98%Color and Shape:SolidMolecular weight:225.22Epiboxidine
CAS:<p>Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.</p>Formula:C10H14N2OColor and Shape:SolidMolecular weight:178.235H-Pyrido[4,3-b]indole
CAS:<p>5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.</p>Formula:C11H8N2Purity:99.6%Color and Shape:SolidMolecular weight:168.24-Butyl-α-agarofuran
CAS:<p>4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.</p>Formula:C18H30OColor and Shape:SolidMolecular weight:262.43Paynantheine
CAS:<p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>Formula:C23H28N2O4Color and Shape:SolidMolecular weight:396.48UCM 549
CAS:<p>UCM 549 is a bioactive chemical.</p>Formula:C19H21NO2Color and Shape:SolidMolecular weight:295.38α-Conotoxin imi
CAS:<p>alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.</p>Formula:C52H78N20O15S4Purity:98%Color and Shape:SolidMolecular weight:1351.56AChE-IN-4
<p>AChE-IN-4 is an acetylcholine esterase inhibitor (AChEI) with an IC50 value of 24.1 μM.</p>Formula:C32H25BrN6O4SColor and Shape:SolidMolecular weight:669.55Deoxynojirimycin Tetrabenzyl Ether
CAS:<p>Deoxynojirimycin tetrabenzyl ether aids in making 1-dNM, a strong α-glucosidase I & II blocker.</p>Formula:C34H37NO4Color and Shape:SolidMolecular weight:523.673Antidepressant agent 3
<p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>Formula:C17H30ClN5O2SColor and Shape:SolidMolecular weight:403.97β-Amyloid Protein Precursor 770 (135-155)
CAS:<p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>Formula:C116H172N35O31S2Purity:98%Color and Shape:SolidMolecular weight:2617.96Duloxetine D3 hydrochloride
CAS:<p>Duloxetine D3 HCl is a deuterium-labeled SNRI, treats depression/GAD, Ki 4.6 nM.</p>Formula:C18H20ClNOSPurity:98%Color and Shape:SolidMolecular weight:336.89Cloxacepride
CAS:<p>cloxacepride is a CaM antagonist that is used to treat asthma disease.</p>Formula:C22H27Cl2N3O4Purity:99.62%Color and Shape:SolidMolecular weight:468.37Bis-(-)-8-demethylmaritidine
<p>Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1</p>Color and Shape:Odour SolidWithasomniferolide B
CAS:<p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>Formula:C28H36O4Color and Shape:SolidMolecular weight:436.58MGS0028
CAS:<p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>Formula:C8H8FNO5Color and Shape:SolidMolecular weight:217.15β-Amyloid (1-34)
CAS:<p>This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.</p>Formula:C170H253N47O52Purity:98%Color and Shape:SolidMolecular weight:3787.2BuChE-IN-21
<p>BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.</p>Formula:C16H23NO2Color and Shape:SolidMolecular weight:261.17288mHTT-IN-1
CAS:<p>mHTT-IN-1 is a potent inhibitor of toxic mHTT, linked to Huntington's disease, with an EC50 of 46 nM.</p>Formula:C18H19N7OSColor and Shape:SolidMolecular weight:381.455-HT2A receptor agonist-5
CAS:<p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>Formula:C23H29N3OColor and Shape:SolidMolecular weight:363.5M 8218
CAS:<p>M 8218 is a bioactive chemical.</p>Formula:C20H29NO2Color and Shape:SolidMolecular weight:315.452-Methyl-1-indanone
CAS:<p>2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.</p>Formula:C10H10OPurity:96.6%Color and Shape:SolidMolecular weight:146.19MK-0969
CAS:<p>MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.</p>Formula:C24H30F2N4O2Color and Shape:SolidMolecular weight:444.52p-HTAA
CAS:<p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>Formula:C24H16O4S5Color and Shape:SolidMolecular weight:528.71Cannabidiolic acid methyl ester
CAS:<p>Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.</p>Formula:C23H32O4Color and Shape:SolidMolecular weight:372.5Antidepressant agent 4
<p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>Formula:C19H38ClN5O2SColor and Shape:SolidMolecular weight:436.06BIBD-124
CAS:<p>BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.</p>Formula:C19H24FN3O3Color and Shape:SolidMolecular weight:361.41(R)-Citalopram oxalate
CAS:<p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>Formula:C22H23FN2O5Purity:99.76%Color and Shape:White SolidMolecular weight:414.43FRM-024
CAS:<p>FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment of</p>Formula:C22H22ClN5O2Color and Shape:SolidMolecular weight:423.9Perlapine
CAS:<p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>Formula:C19H21N3Color and Shape:SolidMolecular weight:291.39LtIA-F
<p>LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.</p>Formula:C86H121N25O22S4Color and Shape:SolidMolecular weight:1985.31AChE-IN-87
<p>AChE-IN-87 is an AChE inhibitor with an IC50 of 0.05 μM and a Ki of 16.93 nM. It exhibits no cytotoxicity toward 3T3 cells and is suitable for Alzheimer's disease (AD) research.</p>Formula:C32H39N3O12S2Color and Shape:SolidMolecular weight:721.19752Sabirnetug
CAS:<p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>Color and Shape:Liquid
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