Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(942 products)
- ACK(1 products)
- AChR(575 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,948 products)
- BACE(36 products)
- Beta Amyloid(205 products)
- CaMK(69 products)
- Cyclooxygenase (COX) Inhibitors(565 products)
- Dopamine Receptor(409 products)
- GABA Receptor(336 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(359 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(27 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
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Found 5390 products of "Neuroscience"
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SAHM1
CAS:<p>Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.</p>Formula:C94H162N36O23SPurity:98%Color and Shape:SolidMolecular weight:2196.586,7-dimethylisatin
CAS:<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Formula:C10H9NO2Purity:98.98%Color and Shape:SolidMolecular weight:175.18β-Amyloid (4-10)
CAS:Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances inFormula:C39H52N12O12Purity:98%Color and Shape:SolidMolecular weight:880.9β-Amyloid (35-42)
CAS:<p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>Formula:C33H60N8O9SPurity:98%Color and Shape:SolidMolecular weight:744.942-Methyl-N,N-dimethyltryptamine
CAS:<p>2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.</p>Formula:C13H18N2Color and Shape:SolidMolecular weight:202.3BChE-IN-35
<p>BChE-IN-35 (Azo-9) is an inhibitor of BChE. This compound exhibits dynamic cis/trans conformational changes, with the cis isomer preferentially binding to BChE. Additionally, BChE-IN-35 can be utilized in research on Alzheimer's disease (AD).</p>Formula:C35H39N5O2Color and Shape:SolidMolecular weight:561.72Pozanicline hydrochloride
<p>Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.</p>Formula:C11H17ClN2OPurity:97.13% - 99.81%Color and Shape:SolidMolecular weight:228.72R-(+)-Cotinine
CAS:<p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>Formula:C10H12N2OColor and Shape:SolidMolecular weight:176.22β-Secretase Inhibitor II
CAS:<p>β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase.</p>Formula:C25H39N3O5Color and Shape:SolidMolecular weight:461.59Alosetron-d3
CAS:<p>Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.</p>Formula:C17H18N4OPurity:98%Color and Shape:SolidMolecular weight:297.37SSAO inhibitor-1
CAS:<p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>Formula:C17H24FN5O2Color and Shape:SolidMolecular weight:349.415-HT1AR/5-HT6R ligand-1
<p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>Formula:C25H29ClN4O2SColor and Shape:SolidMolecular weight:485.04CUR-IPA
<p>CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.</p>Formula:C43H38N2O8Color and Shape:SolidMolecular weight:710.77Cianopramine hydrochloride
CAS:<p>Cianopramine hydrochloride is a bio-active chemical.</p>Formula:C20H24ClN3Color and Shape:SolidMolecular weight:341.88β-Amyloid (1-40)
CAS:<p>Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.</p>Formula:C194H295N53O58SPurity:98%Color and Shape:SolidMolecular weight:4329.82Oxatomide
CAS:<p>Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).</p>Formula:C27H30N4OPurity:98.82% - 99.72%Color and Shape:White PowderMolecular weight:426.55epi-Aszonalenin A
CAS:<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Formula:C35H43Cl2F2N5O4Color and Shape:SolidMolecular weight:706.65JPC0323
<p>JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequate</p>Formula:C22H43NO4Purity:98%Color and Shape:SolidMolecular weight:385.58Nardoguaianone J
CAS:<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Formula:C15H22O2Color and Shape:SolidMolecular weight:234.33ZL-1101
<p>ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.</p>Color and Shape:Odour LiquidPF-06827443
<p>PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.</p>Formula:C24H24N2O4Color and Shape:SolidMolecular weight:404.47Aloveroside A
CAS:<p>Aloveroside A, a triglucosylnaphthalene derivative extracted from Aloe vera using ethanol, exhibits modest inhibitory activity against bACE, demonstrating</p>Formula:C30H40O17Color and Shape:SolidMolecular weight:672.63Lesogaberan napadisylate
CAS:<p>Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.</p>Formula:C13H17FNO5PSColor and Shape:SolidMolecular weight:349.31SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Formula:C25H30ClN3O3SColor and Shape:SolidMolecular weight:488.04Vortioxetine D8
CAS:<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Formula:C18H22N2SPurity:98%Color and Shape:SolidMolecular weight:306.5Anagyrine hydrochloride
CAS:<p>Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.</p>Formula:C15H21ClN2OColor and Shape:SolidMolecular weight:280.79Dexmedetomidine
CAS:Formula:C13H16N2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:200.29Dexetimide
CAS:<p>Dexetimide, a muscarinic receptor antagonist, treats neuroleptic-induced parkinsonism.</p>Formula:C23H26N2O2Color and Shape:SolidMolecular weight:362.46Ladostigil hemitartrate
CAS:<p>Ladostigil hemitartrate (TV-3326) inhibits cholinesterase & MAO-B, has neuroprotective traits, and is used in depression & Alzheimer's research.</p>Formula:C20H26N2O8Color and Shape:SolidMolecular weight:422.434SKF-96365
CAS:Formula:C22H26N2O3·HClPurity:>98%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:402.92VU0364770 hydrochloride
CAS:VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).Formula:C12H10Cl2N2OPurity:98%Color and Shape:SolidMolecular weight:269.13LY-2584702 Tosylate
CAS:Formula:C21H19F4N7·C7H8O3SPurity:>95.0%(HPLC)Color and Shape:White to Yellow powder to crystalMolecular weight:617.62Clomipramine Hydrochloride (Standard)
CAS:Clomipramine Hydrochloride (Standard) is the standard substance of Clomipramine Hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.Formula:C19H23ClN2·HClMolecular weight:351.31Fosthiazate (Standard)
CAS:Fosthiazate (Standard) is the standard substance of Fosthiazate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., by inhibiting acetylcholinesterase synthesis .Formula:C9H18NO3PS2Molecular weight:283.35Isoimperatorin
CAS:Formula:C16H14O4Purity:>97.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:270.28Mofegiline hydrochloride
CAS:<p>Mofegiline hydrochloride is a potent and selective enzyme-activated irreversible MAO-B inhibitor.</p>Formula:C11H14ClF2NPurity:98%Color and Shape:SolidMolecular weight:233.69Mubritinib
CAS:Formula:C25H23F3N4O2Purity:>98.0%(HPLC)Color and Shape:White to Gray to Brown powder to crystalMolecular weight:468.48Altanserin
CAS:<p>Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.</p>Formula:C22H22FN3O2SColor and Shape:SolidMolecular weight:411.49Isoprocarb
CAS:<p>Isoprocarb is a metabolite of the pesticide.</p>Formula:C11H15NO2Color and Shape:SolidMolecular weight:193.24Anti-APP Antibody (8U619)
<p>Anti-APP Antibody (8U619) is an antibody targeting APP. Anti-APP Antibody (8U619) can be used in ELISA, WB, IF.</p>Color and Shape:Odour LiquidL-655708
CAS:<p>L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.</p>Formula:C18H19N3O4Purity:98.41%Color and Shape:PowderMolecular weight:341.36Fluvoxamine
CAS:<p>Fluvoxamine (DU-23000) is a selective, orally available 5-HT and serotonin reuptake inhibitor (SSRI) exhibiting antidepressant effects.</p>Formula:C15H21F3N2O2Color and Shape:SolidMolecular weight:318.33MNS
CAS:Formula:C9H7NO4Purity:>98.0%(GC)Color and Shape:Light yellow to Yellow to Green powder to crystalMolecular weight:193.16Trihexyphenidyl Hydrochloride
CAS:Formula:C20H31NO·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:337.93SU 1498
CAS:Formula:C25H30N2O2Purity:>98.0%(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:390.5310,10'-Dimethyl-9,9'-biacridinium Dinitrate [for Chemiluminescence Research]
CAS:Formula:C28H22N4O6Purity:>97.0%(HPLC)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:510.51Cytidine 5'-Diphosphocholine
CAS:Formula:C14H26N4O11P2Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalineMolecular weight:488.33PD 184352
CAS:Formula:C17H14ClF2IN2O2Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:478.66WHI-P180 Hydrochloride
CAS:Formula:C16H15N3O3·HClPurity:>97.0%(T)(HPLC)Color and Shape:White to Light gray to Light yellow powder to crystalMolecular weight:333.77
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