Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(36 products)
- Cysteine Protease(111 products)
- DPP-4(24 products)
- Glutaminase(44 products)
- HIV Protease(501 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(89 products)
- Serine Protease(54 products)
- p97(15 products)
Show 3 more subcategories
Found 993 products of "Proteases/Proteasome"
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LSP-249
CAS:LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell.Formula:C24H22ClN5OPurity:99.51%Color and Shape:SolidMolecular weight:431.92Gly-Pro-pNA hydrochloride
CAS:Gly-Pro-pNA hydrochloride (Gly-Pro p-nitroanilide hydrochloride) is a dipeptidyl peptidase inhibitor that inhibits dipeptidyl peptidase II, dipeptidyl peptidaseFormula:C13H17ClN4O4Purity:99.84%Color and Shape:SolidMolecular weight:328.75(2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid
CAS:Formula:C16H24N2O4Purity:98%Color and Shape:SolidMolecular weight:308.3728Ref: IN-DA00370Q
1g132.00€5g223.00€10g532.00€25gTo inquire50gTo inquire100gTo inquire10mg29.00€250gTo inquire50mg34.00€100mg44.00€250mg68.00€2-Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, ethyl ester, (2S,3S)-
CAS:Formula:C17H30N2O5Purity:98%Color and Shape:SolidMolecular weight:342.4305PMSF
CAS:PMSF (Phenylmethylsulfonyl fluoride) is an irreversible inhibitor of serine/cysteine protease , preparation of cell lysates. High-Quality, Low-Cost!Formula:C7H7FO2SPurity:97.75% - 99.88%Color and Shape:White To Cream SolidMolecular weight:174.19Sofosbuvir impurity F
CAS:Sofosbuvir impurity F (Sofosbuvir 3',5'-Bis-(S)-phosphate) is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNAFormula:C34H45FN4O13P2Purity:98.05%Color and Shape:SolidMolecular weight:798.69(Rac)-Telinavir
CAS:N1 compound with anti-HIV activity; contains dimethyl, phenyl, quinoline groups.
Formula:C33H44N6O5Purity:99.30%Color and Shape:SolidMolecular weight:604.74Ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid
CAS:Formula:C14H24N2O10Purity:97%Color and Shape:SolidMolecular weight:380.34783-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-, (3S,4aS,8aS)-, methanesulfonate (1:1)
CAS:Formula:C33H49N3O7S2Purity:96%Color and Shape:SolidMolecular weight:663.8881Avoralstat
CAS:Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.Formula:C28H27N5O5Purity:99.77%Color and Shape:SolidMolecular weight:513.54Mecarbinate
CAS:Mecarbinate (Dimecarbin) is arbidol hydrochloride's chemical intermediate.Formula:C13H15NO3Purity:99.28%Color and Shape:Off-White Crystalline PowderMolecular weight:233.26Flanvotumab
CAS:Flanvotumab (IMC-20D7S) is a humanized antibody targeting TYRP1 with strong antitumor effects via NK cells and ADCC.Purity:> 95%Color and Shape:LiquidMolecular weight:145.42 kDaAnisindione
CAS:Anisindione, a synthetic indanedione, inhibits vitamin K, blocking factors II, VII, IX, X, and proteins C, S.Formula:C16H12O3Purity:98.25%Color and Shape:Pale Yellow Crystals From Acetic Acid Or Ethanol SolidMolecular weight:252.26Dabigatran etexilate
CAS:Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.Formula:C34H41N7O5Purity:98.19% - 99.98%Color and Shape:White PowderMolecular weight:627.73(Rac)-Telmesteine
CAS:(Rac)-Telmesteine (3,4-Thiazolidinedicarboxylic Acid 3-Ethyl Ester) is an inhibitor of protease and is thus a suitable enzyme stabilizer.Formula:C7H11NO4SPurity:99.91%Color and Shape:SolidMolecular weight:205.23Retagliptin Phosphate
CAS:Retagliptin Phosphate (SP 2086) is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes.Formula:C19H21F6N4O7PPurity:98.70%Color and Shape:SolidMolecular weight:562.36Ref: TM-T12710
1mg34.00€2mg42.00€5mg60.00€10mg87.00€25mg161.00€50mg245.00€100mgTo inquire1mL*10mM (DMSO)79.00€Trelagliptin
CAS:Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.Formula:C18H20FN5O2Purity:98.88%Color and Shape:SolidMolecular weight:357.38BLT-1
CAS:BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.Formula:C12H23N3SPurity:97.97%Color and Shape:SolidMolecular weight:241.4Ref: TM-T14667
1mg43.00€2mg56.00€5mg93.00€10mg152.00€25mg259.00€50mg409.00€100mg592.00€1mL*10mM (DMSO)90.00€MK-0608
CAS:MK-0608 is an orally bioavailable HCV replication inhibitor in vitro(EC50 = 0.3 μM and EC90=1.3 μM in the subgenomic-replicon assay).Formula:C12H16N4O4Purity:98.48%Color and Shape:SolidMolecular weight:280.28Ref: TM-T16088
1mg46.00€2mg59.00€5mg96.00€10mg133.00€25mg250.00€50mg411.00€100mg660.00€1mL*10mM (DMSO)92.00€Dolutegravir intermediate-1
CAS:Dolutegravir intermediate-1 is a synthetic precursor for HIV-1 treatment from patent WO 2016125192 A2.Formula:C13H17NO8Purity:99.52%Color and Shape:SolidMolecular weight:315.28ML604440
CAS:ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.Formula:C17H24BF3N2O4Purity:97.06%Color and Shape:SolidMolecular weight:388.19Ref: TM-T12079
1mg109.00€2mg158.00€5mg259.00€10mg409.00€25mg677.00€50mg954.00€100mg1,288.00€200mg1,728.00€1mL*10mM (DMSO)285.00€RAMB4
CAS:RAMB4 (PTP1B-IN-9) is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity.Formula:C19H13Cl4NOPurity:98.89% - 99.38%Color and Shape:SolidMolecular weight:413.12Ruzasvir
CAS:Ruzasvir (MK-8408) is a novel and potent pan-genotypic inhibitor of hepatitis C virus NS5A with antiviral activity.Formula:C49H55FN10O7SPurity:96.87% - 99.93%Color and Shape:SolidMolecular weight:947.09Salicylanilide
CAS:Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.
Formula:C13H11NO2Purity:99.55%Color and Shape:White To Off-White Crystalline PowderMolecular weight:213.23Probenecid
CAS:Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.Formula:C13H19NO4SPurity:98.95% - 99.84%Color and Shape:Crystals From Dil Alcohol Pleasant Aftertaste (Ntp 1992)Molecular weight:285.36BJJF078
CAS:BJJF078, an aminopiperidine, inhibits human/mouse TG2 (IC50: 41/54 nM) and TG1 (IC50: 0.16 μM), may be used in MS studies.Formula:C27H29N3O6SPurity:99.56%Color and Shape:SoildMolecular weight:523.6LDN-27219
CAS:LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.Formula:C20H16N4O2S2Purity:99.01% - 99.38%Color and Shape:SolidMolecular weight:408.5Ref: TM-T11831
1mg35.00€5mg66.00€10mg92.00€25mg160.00€50mg234.00€100mg351.00€200mg515.00€1mL*10mM (DMSO)71.00€CL-82198
CAS:CL-82198, a selective MMP-13 inhibitor, serves as a pharmacological intervention to halt the progression of osteoarthritis (OA).Formula:C17H22N2O3Purity:95.91%Color and Shape:SolidMolecular weight:302.37Ref: TM-T14978
5mg47.00€10mg73.00€25mg153.00€50mg243.00€100mg378.00€200mg552.00€500mg868.00€1mL*10mM (DMSO)50.00€(ETHYLENEDINITRILO)TETRAACETIC ACID, TRISODIUM SALT HYDRATE
CAS:Formula:C10H18N2NaO9Purity:97%Color and Shape:SolidMolecular weight:333.2477Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Formula:C18H25N3O2·H2OPurity:99.52%Color and Shape:SolidMolecular weight:333.43Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Formula:C19H14BrClN4OColor and Shape:SolidMolecular weight:429.7STK33-IN-1
CAS:STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.Formula:C24H27N7O2Color and Shape:SolidMolecular weight:445.527Ac-PAL-AMC
CAS:Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.Formula:C26H34N4O6Color and Shape:SolidMolecular weight:498.57Ichorcumab
CAS:Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.
Color and Shape:LiquidTalabostat
CAS:Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.Formula:C9H19BN2O3Color and Shape:SolidMolecular weight:214.07PROTAC CG167
PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)Formula:C65H79N13O11SColor and Shape:SolidMolecular weight:1250.47HCV-IN-7 hydrochloride
CAS:HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.Formula:C40H50Cl2N8O6SPurity:98%Color and Shape:SolidMolecular weight:841.85Alisporivir
CAS:Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.Formula:C63H113N11O12Purity:99.95%Color and Shape:SolidMolecular weight:1216.64RXP470
CAS:RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).Formula:C35H35BrClN4O10PColor and Shape:SolidMolecular weight:818Nitidanin
Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.Formula:C21H24O8Color and Shape:SolidMolecular weight:404.41515,16-Dihydrotanshindiol C
15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.Formula:C18H18O5Color and Shape:SolidMolecular weight:314.337Relacatib
CAS:Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.Formula:C27H32N4O6SColor and Shape:SolidMolecular weight:540.645-epi-Arvestonate A
CAS:5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.
Formula:C16H26O5Color and Shape:SolidMolecular weight:298.37Bortezomib analog
Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.Color and Shape:Odour SolidHIV-1 Rev (34-50)
CAS:HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity.Formula:C97H173N51O24Purity:99.91%Color and Shape:SolidMolecular weight:2437.74Grazoprevir potassium salt
CAS:Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.
Formula:C38H49KN6O9SColor and Shape:SolidMolecular weight:805AL-611
CAS:AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).
Formula:C25H33F2N6O8PColor and Shape:SolidMolecular weight:614.544PSI-7409
CAS:PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).
Formula:C10H16FN2O14P3Purity:98%Color and Shape:SolidMolecular weight:500.16Neutrophil elastase inhibitor 4
Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.Formula:C20H21N3O5Color and Shape:SolidMolecular weight:383.4AP-C2
CAS:AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.Formula:C18H16N4SPurity:99.99%Color and Shape:SoildMolecular weight:320.41
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![2-Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbony…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA0048C1.webp&w=3840&q=75)
