Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase(67 products)
- Hedgehog/Smoothened(49 products)
- Hippo pathway(7 products)
- JAK(245 products)
- Porcupine(8 products)
- ROCK(62 products)
- STAT(105 products)
- Stem Cells(129 products)
- TGF-beta/Smad(70 products)
- Wnt/beta-catenin(65 products)
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Found 436 products for "Stem Cell and Derivatives".
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G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formula:C22H19F2NO3Purity:97.3%Color and Shape:Yellow SolidMolecular weight:383.39Ref: TM-T8742
1mg35.00€5mg71.00€1mL*10mM (DMSO)78.00€10mg96.00€25mg172.00€50mg248.00€100mg348.00€200mg470.00€Decernotinib
CAS:Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.Formula:C18H19F3N6OPurity:99.28% - >99.99%Color and Shape:SolidMolecular weight:392.38Ref: TM-T2636
1mg34.00€2mg48.00€5mg71.00€1mL*10mM (DMSO)79.00€10mg99.00€25mg197.00€50mg295.00€100mg447.00€LGK974
CAS:LGK974 (NVP-LGK974) is a selective PORCN inhibitor that blocks Wnt signaling, used in metastatic colorectal and head/neck cancer trials. IC50: 0.4 nM.Formula:C23H20N6OPurity:99.04% - >99.99%Color and Shape:SolidMolecular weight:396.44Ref: TM-T2618
1mg46.00€2mg62.00€5mg90.00€1mL*10mM (DMSO)90.00€10mg156.00€25mg288.00€50mg515.00€100mg737.00€γ-secretase modulator 1 hydrochloride
CAS:gamma-secretase inhibitior-1 is a gamma-secretase modulator that is useful to Alzheimer's disease [1].Formula:C24H25ClN4OSPurity:98%Color and Shape:SolidMolecular weight:453(E)-SIS3
CAS:(E)-SIS3 (SIS3) is a Smad3 inhibitor (IC50=3 μM) selective.inhibits the differentiation of fibroblasts into myofibroblasts via TGF-β1. High-Quality, Low-Cost!Formula:C28H27N3O3·HClPurity:95.64% - 98%Color and Shape:Yellow SolidMolecular weight:489.99Ref: TM-T3636
1mg40.00€2mg54.00€5mg105.00€1mL*10mM (DMSO)114.00€10mg164.00€25mg326.00€50mg485.00€100mg692.00€500mg1,395.00€AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purity:98% - 99.91%Color and Shape:SolidMolecular weight:545.63Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formula:C23H25ClFN7OPurity:99.33% - 99.86%Color and Shape:SolidMolecular weight:469.94Protosappanin A
CAS:Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.Formula:C15H12O5Purity:99.42% - 99.82%Color and Shape:White SolidMolecular weight:272.25Ref: TM-TJS1779
1mg88.00€1mL*10mM (DMSO)178.00€5mg195.00€10mg318.00€25mg523.00€50mg743.00€100mg999.00€JAK3-IN-6
CAS:JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nMFormula:C19H18N4O3Purity:99.94% - 99.94%Color and Shape:SolidMolecular weight:350.37Pyridone 6
CAS:Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).Formula:C18H16FN3OPurity:97.1% - 98.74%Color and Shape:SolidMolecular weight:309.34Ref: TM-T3080
1mg50.00€2mg71.00€5mg105.00€1mL*10mM (DMSO)110.00€10mg173.00€25mg358.00€50mg587.00€100mg888.00€200mg1,198.00€WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formula:C16H14BrN3O3Purity:98% - 99.67%Color and Shape:SolidMolecular weight:376.2Delgocitinib EtOH
CAS:Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formula:C18H24N6O2Color and Shape:SolidMolecular weight:356.43CEP-33779
CAS:CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.Formula:C24H26N6O2SPurity:98.24% - ≥95%Color and Shape:Yellow SolidMolecular weight:462.57Ref: TM-T6122
1mg43.00€2mg56.00€5mg93.00€1mL*10mM (DMSO)94.00€10mg137.00€25mg231.00€50mg356.00€100mg530.00€500mg1,153.00€Tofacitinib Citrate
CAS:Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).Formula:C22H28N6O8Purity:99.19% - 99.86%Color and Shape:White SolidMolecular weight:504.49Upadacitinib
CAS:Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.Formula:C17H19F3N6OPurity:98.96% - 99.94%Color and Shape:SolidMolecular weight:380.37Ref: TM-T7503
1mL*10mM (DMSO)44.00€2mg55.00€5mg89.00€10mg116.00€25mg198.00€50mg276.00€100mg389.00€200mg595.00€WHI-P97
CAS:WHI-P97 is a rationally designed potent inhibitor of JAK-3.Formula:C16H13Br2N3O3Purity:99.93%Color and Shape:SolidMolecular weight:455.1ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurity:98.05% - 99.48%Color and Shape:White SolidMolecular weight:367.91JANEX-1
CAS:JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formula:C16H15N3O3Purity:98% - 99.81%Color and Shape:SolidMolecular weight:297.31Ruxolitinib (S enantiomer)
CAS:Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.Formula:C17H18N6Purity:99.37% - 99.79%Color and Shape:SolidMolecular weight:306.36
