Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1504 products of "Autophagy"
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RSVA405
CAS:RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitorFormula:C17H20N4O2Purity:99.30%Color and Shape:SolidMolecular weight:312.37Zebularine
CAS:Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.Formula:C9H12N2O5Purity:99.04% - >99.99%Color and Shape:SolidMolecular weight:228.2Cryptotanshinone
CAS:Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.Formula:C19H20O3Purity:97.94% - ≥95%Color and Shape:Orange Needle CrystalMolecular weight:296.36Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formula:C26H27NO9·HClPurity:98.91% - 99.96%Color and Shape:SolidMolecular weight:533.95GSK2606414
CAS:GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase（PERK）inhibitor.Cost-effective and quality-assured.Formula:C24H20F3N5OPurity:98% - >99.99%Color and Shape:SolidMolecular weight:451.44(+)-JQ-1
CAS:(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formula:C23H25ClN4O2SPurity:97.57% - 99.97%Color and Shape:SolidMolecular weight:456.99Ref: TM-T2110
1mg34.00€2mg42.00€5mg57.00€10mg74.00€25mg90.00€50mg137.00€100mg178.00€200mg268.00€500mg485.00€1mL*10mM (DMSO)63.00€Juglanin
CAS:Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.Formula:C20H18O10Purity:98.8% - 99.33%Color and Shape:SolidMolecular weight:418.35LYS01
CAS:LYS01 free base is a new lysosomal autophagy inhibitor.Formula:C23H23Cl2N5Purity:98.28%Color and Shape:SolidMolecular weight:440.37Meglutol
CAS:Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.Formula:C6H10O5Purity:99.73% - 99.94%Color and Shape:SolidMolecular weight:162.14MRT68921 dihydrochloride
CAS:MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).Formula:C25H36Cl2N6OPurity:98.91% - 99.92%Color and Shape:SolidMolecular weight:507.4994,4'-Dimethoxychalcone
CAS:4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.Formula:C17H16O3Purity:99.57%Color and Shape:SolidMolecular weight:268.31Ref: TM-T7985
2mg34.00€5mg47.00€10mg62.00€25mg96.00€50mg140.00€100mg215.00€200mg318.00€1mL*10mM (DMSO)94.00€Hoechst 33342 trihydrochloride
CAS:Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.Formula:C27H31Cl3N6OPurity:98.73% - ≥98%Color and Shape:SolidMolecular weight:561.93Ixazomib citrate
CAS:Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).Formula:C20H23BCl2N2O9Purity:98.37% - >99.99%Color and Shape:SolidMolecular weight:517.12MG-132
CAS:MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!Formula:C26H41N3O5Purity:95% - 99.99%Color and Shape:White To Off-White PowderMolecular weight:475.62Ref: TM-T2154
10mg46.00€25mg84.00€50mg137.00€100mg205.00€200mg356.00€500mg447.00€1mL*10mM (DMSO)44.00€Vps34-IN-1
CAS:Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.Formula:C21H24ClN7OPurity:97.04%Color and Shape:SolidMolecular weight:425.91Ref: TM-T7015
1mg43.00€2mg56.00€5mg88.00€10mg124.00€25mg207.00€50mg333.00€100mg477.00€1mL*10mM (DMSO)96.00€SAR405
CAS:SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.Formula:C19H21ClF3N5O2Purity:99.42% - 99.99%Color and Shape:SolidMolecular weight:443.85Ref: TM-T12831L
1mg56.00€5mg108.00€10mg167.00€25mg269.00€50mg399.00€100mg590.00€1mL*10mM (DMSO)105.00€AZ304
CAS:AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).Formula:C27H25N5O2Purity:99.82%Color and Shape:SolidMolecular weight:451.52KB-R7943 mesylate
CAS:KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.Formula:C17H21N3O6S2Purity:99.88% - ≥95%Color and Shape:SolidMolecular weight:427.5Briciclib
CAS:Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.Formula:C19H23O10PSPurity:98% - 99.84%Color and Shape:SolidMolecular weight:474.42Ref: TM-T3207
1mg44.00€2mg54.00€5mg84.00€10mg119.00€25mg236.00€50mg356.00€100mg530.00€500mg1,153.00€1mL*10mM (DMSO)93.00€Hoechst 33342
CAS:Hoechst 33342 (bisBenzimide H 33342) is a benzimidazole fluorescent dye and a cell-permeable fluorescent DNA dye. High-Quality, Low-Cost!Formula:C27H28N6OPurity:98.12% - 99.75%Color and Shape:Yellow-Green PowderMolecular weight:452.55Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purity:99.97% - >99.99%Color and Shape:SolidMolecular weight:346.42Ref: TM-T4672
1mg90.00€5mg203.00€10mg350.00€25mg578.00€50mg797.00€100mg1,071.00€500mg2,187.00€1mL*10mM (DMSO)224.00€Actein
CAS:Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.Formula:C37H56O11Purity:≥98%Color and Shape:Brown PowderMolecular weight:676.83Tempol
CAS:Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.Formula:C9H18NO2Purity:97% - 99.98%Color and Shape:4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesMolecular weight:172.25Peretinoin
CAS:Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.Formula:C20H30O2Purity:97.23%Color and Shape:SolidMolecular weight:302.45Ref: TM-TQ0064
1mg38.00€2mg49.00€5mg84.00€10mg119.00€25mg219.00€50mg380.00€100mg567.00€500mg1,215.00€1mL*10mM (DMSO)93.00€LC3-mHTT-IN-AN2
CAS:LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.Formula:C15H10O4Purity:98.05% - ≥98%Color and Shape:SolidMolecular weight:254.24Rabusertib
CAS:Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.
Formula:C18H22BrN5O3Purity:98.86% - 99.87%Color and Shape:SolidMolecular weight:436.3SN-38
CAS:SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM).Formula:C22H20N2O5Purity:98% - 99.97%Color and Shape:Light-Yellow SolidMolecular weight:392.4AS1842856
CAS:AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy inhibitory activity. Cost-effective and quality-assured.Formula:C18H22FN3O3Purity:99.36% - >99.99%Color and Shape:SolidMolecular weight:347.38DMH-1
CAS:DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.
Formula:C24H20N4OPurity:98% - 99.92%Color and Shape:SolidMolecular weight:380.44SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFormula:C14H8N2OPurity:97.63% - 99.82%Color and Shape:SolidMolecular weight:220.23Pexmetinib
CAS:Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.Formula:C31H33FN6O3Purity:99.07% - 99.66%Color and Shape:SolidMolecular weight:556.63Vps34-IN-4
CAS:VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)Formula:C21H25N7OPurity:98.6%Color and Shape:SolidMolecular weight:391.47Ref: TM-T7944
1mg63.00€5mg137.00€10mg215.00€25mg378.00€50mg537.00€100mg713.00€200mg982.00€1mL*10mM (DMSO)150.00€XCT790
CAS:XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).Formula:C23H13F9N4O3SPurity:99% - 99.61%Color and Shape:SolidMolecular weight:596.4220-DEOXYINGENOL
CAS:20-DEOXYINGENOL is a natual product.Formula:C20H28O4Purity:99.98% - ≥95%Color and Shape:SolidMolecular weight:332.43Ref: TM-T5689
1mg34.00€5mg65.00€10mg94.00€25mg137.00€50mg193.00€100mg286.00€200mg423.00€1mL*10mM (DMSO)73.00€U0126
CAS:U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.Formula:C18H16N6S2Purity:99.61%Color and Shape:White SolidMolecular weight:380.49Ref: TM-T21332
1mg47.00€5mg96.00€10mg140.00€25mg255.00€50mg384.00€100mg538.00€200mg827.00€1mL*10mM (DMSO)92.00€Torin 1
CAS:Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.Formula:C35H28F3N5O2Purity:98.3% - 99.33%Color and Shape:SolidMolecular weight:607.62Clinofibrate
CAS:Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.Formula:C28H36O6Purity:>99.99%Color and Shape:White Crystalline PowderMolecular weight:468.58Alginic acid
CAS:Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.Formula:C14H22O13Purity:≥98%Color and Shape:SolidMolecular weight:398.317Tetrahydrocurcumin
CAS:Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.Formula:C21H24O6Purity:97.81% - 98.82%Color and Shape:Solid PowderMolecular weight:372.41Salbutamol hemisulfate
CAS:Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.Formula:C13H21NO3H2O4SPurity:99.35%Color and Shape:White Or Almost White Odourless PowderMolecular weight:576.70Acumapimod
CAS:Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).Formula:C22H19N5O2Purity:≥95%Color and Shape:SolidMolecular weight:385.42Lithocholic acid
CAS:Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!Formula:C24H40O3Purity:98% - 99.93%Color and Shape:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Molecular weight:376.57Scutellarein
CAS:Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.Formula:C15H10O6Purity:98.02% - 99.63%Color and Shape:SolidMolecular weight:286.24Ref: TM-T3319
2mg38.00€5mg52.00€10mg75.00€25mg109.00€50mg159.00€100mg227.00€200mg338.00€1mL*10mM (DMSO)59.00€Vancomycin
CAS:Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibitingFormula:C66H75Cl2N9O24Purity:98.76% - 99.52%Color and Shape:Almost White PowderMolecular weight:1449.25URB-597
CAS:URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.Formula:C20H22N2O3Purity:97.20% - 98.24%Color and Shape:SolidMolecular weight:338.4Tropifexor
CAS:Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.Formula:C29H25F4N3O5SPurity:99.3% - 99.85%Color and Shape:SolidMolecular weight:603.58TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formula:C26H35N7O2SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:509.67Pifithrin-μ
CAS:Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Formula:C8H7NO2SPurity:99.33% - 99.79%Color and Shape:SolidMolecular weight:181.21Valinomycin
CAS:Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes ParkinFormula:C54H90N6O18Purity:95.37% - 97.16%Color and Shape:White SolidMolecular weight:1111.32Eupatilin
CAS:Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Formula:C18H16O7Purity:98.53% - 99%Color and Shape:SolidMolecular weight:344.32LYN-1604
CAS:LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.Formula:C33H43Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:584.62SR9009
CAS:SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.Formula:C20H24ClN3O4SPurity:99.94% - >99.99%Color and Shape:SolidMolecular weight:437.94Ref: TM-T3685
2mg39.00€5mg58.00€10mg93.00€25mg137.00€50mg236.00€100mg384.00€200mg568.00€1mL*10mM (DMSO)64.00€Kaempferol
CAS:Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.Formula:C15H10O6Purity:98% - 99.41%Color and Shape:Yellow Needles From Alcohol And Water SolidMolecular weight:286.24DPN
CAS:DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .Formula:C15H13NO2Purity:99.01%Color and Shape:Off-White SolidMolecular weight:239.27Nutlin-3a
CAS:Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.Formula:C30H30Cl2N4O4Purity:95.62% - 99.71%Color and Shape:SolidMolecular weight:581.49Ref: TM-T6023
1mg50.00€2mg66.00€5mg90.00€10mg156.00€25mg254.00€50mg376.00€100mg557.00€1mL*10mM (DMSO)128.00€FIPI
CAS:FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.Formula:C23H24FN5O2Purity:97.21% - 98.68%Color and Shape:SolidMolecular weight:421.47Quercitrin
CAS:Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.Formula:C21H20O11Purity:98.89% - 99.66%Color and Shape:Yellow Crystals From Dil Methanol Or Ethanol SolidMolecular weight:448.38Quisinostat dihydrochloride
CAS:Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。Formula:C21H28Cl2N6O2Purity:97.13%Color and Shape:SolidMolecular weight:467.39Ref: TM-T6865
1mg62.00€5mg120.00€10mg170.00€25mg294.00€50mg411.00€100mg573.00€200mg807.00€1mL*10mM (DMSO)123.00€3-Bromopyruvic acid
CAS:3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.
Formula:C3H3BrO3Purity:95% - 99.644%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:166.96Fangchinoline
CAS:Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.Formula:C37H40N2O6Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:608.72AZD 6482
CAS:AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Formula:C22H24N4O4Purity:99.87% - 99.95%Color and Shape:SolidMolecular weight:408.45Dioscin
CAS:Dioscin (Collettiside III) is a saponin with antitumor activities.Formula:C45H72O16Purity:99.85% - 99.87%Color and Shape:SolidMolecular weight:869.04Ref: TM-T6473
5mg34.00€10mg42.00€25mg58.00€50mg81.00€100mg105.00€200mg152.00€500mg245.00€1mL*10mM (DMSO)52.00€GLPG1837
CAS:GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.Formula:C16H20N4O3SPurity:99.64% - 99.91%Color and Shape:SolidMolecular weight:348.42Neflamapimod
CAS:Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.Formula:C19H9Cl2F2N3OSPurity:97.88% - 99.75%Color and Shape:SolidMolecular weight:436.26Turofexorate Isopropyl
CAS:Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM
Formula:C25H24F2N2O3Purity:98.55% - 99.73%Color and Shape:SolidMolecular weight:438.47SGI-1776
CAS:SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.Formula:C20H22F3N5OPurity:99.3% - >99.99%Color and Shape:SolidMolecular weight:405.42Milciclib
CAS:Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.Formula:C25H32N8OPurity:99.28%Color and Shape:SolidMolecular weight:460.57Ref: TM-T6081
1mg49.00€5mg101.00€10mg168.00€25mg356.00€50mg572.00€100mg858.00€200mg1,153.00€1mL*10mM (DMSO)104.00€STF-62247
CAS:STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.Formula:C15H13N3SPurity:99.6% - 99.67%Color and Shape:SolidMolecular weight:267.35Fenretinide
CAS:Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.Formula:C26H33NO2Purity:98% - 99.68%Color and Shape:Yellow PowderMolecular weight:391.55CD437
CAS:CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.Formula:C27H26O3Purity:98.92% - 99.63%Color and Shape:SolidMolecular weight:398.49FERULIC ACID METHYL ESTER
CAS:FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Formula:C11H12O4Purity:99.66% - 99.95%Color and Shape:SolidMolecular weight:208.21LRRK2-IN-1
CAS:LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Formula:C31H38N8O3Purity:98% - 98.82%Color and Shape:SolidMolecular weight:570.69Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14H-89 dihydrochloride
CAS:H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).Formula:C20H20BrN3O2S·2HClPurity:98.22% - >99.99%Color and Shape:SolidMolecular weight:519.28Ref: TM-T6250
5mg39.00€10mg58.00€25mg106.00€50mg202.00€100mg344.00€200mg512.00€500mg815.00€1mL*10mM (DMSO)52.00€PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formula:C16H13NO3Purity:98.63% - >99.99%Color and Shape:Yellow SolidMolecular weight:267.28Ref: TM-T2623
5mg38.00€10mg50.00€25mg78.00€50mg101.00€100mg168.00€200mg250.00€500mg421.00€1mL*10mM (DMSO)55.00€ML327
CAS:ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).Formula:C19H18N4O4Purity:98.47%Color and Shape:SolidMolecular weight:366.37Ref: TM-T4252
1mg47.00€2mg62.00€5mg92.00€10mg137.00€25mg222.00€50mg356.00€100mg612.00€200mg850.00€1mL*10mM (DMSO)101.00€Sitagliptin phosphate
CAS:Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor.Formula:C16H18F6N5O5PPurity:99.72% - 99.91%Color and Shape:White SolidMolecular weight:505.31KN-92 phosphate
CAS:KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93.Formula:C24H28ClN2O7PSPurity:99.86%Color and Shape:SolidMolecular weight:554.98Ref: TM-T4530
2mg34.00€5mg66.00€10mg100.00€25mg166.00€50mg245.00€100mg349.00€200mg495.00€1mL*10mM (DMSO)80.00€Wortmannin
CAS:Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.Formula:C23H24O8Purity:95.84% - 99.77%Color and Shape:White SolidMolecular weight:428.43Ref: TM-T6283
1mg35.00€2mg50.00€5mg75.00€10mg113.00€25mg224.00€50mg385.00€100mg570.00€1mL*10mM (DMSO)84.00€Crizotinib hydrochloride
CAS:Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formula:C21H23Cl3FN5OPurity:98.73% - 98.87%Color and Shape:SolidMolecular weight:486.8Ref: TM-T8399
5mg34.00€10mg50.00€25mg78.00€50mg94.00€100mg131.00€200mg162.00€500mg215.00€1mL*10mM (DMSO)56.00€Danusertib
CAS:Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formula:C26H30N6O3Purity:97.88% - 98.79%Color and Shape:White PowderMolecular weight:474.553-Methyladenine
CAS:3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).Formula:C6H7N5Purity:98% - 99.51%Color and Shape:SolidMolecular weight:149.15WYC-209
CAS:WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).Formula:C20H20N2O3SPurity:99.77%Color and Shape:SolidMolecular weight:368.45Salirasib
CAS:Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formula:C22H30O2SPurity:99.45%Color and Shape:SolidMolecular weight:358.54Ref: TM-T6163
5mg34.00€10mg50.00€25mg90.00€50mg150.00€100mg210.00€200mg344.00€500mg567.00€1mL*10mM (DMSO)56.00€MRT67307 HCl (1190378-57-4(free base))
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).Formula:C26H37ClN6O2Purity:98.19%Color and Shape:SolidMolecular weight:501.07Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purity:98.11% - 99.87%Color and Shape:SolidMolecular weight:718.08TA-02
CAS:TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.Formula:C20H13F2N3Purity:99.35% - 99.79%Color and Shape:SolidMolecular weight:333.33Ref: TM-T4646
5mg37.00€10mg55.00€25mg99.00€50mg152.00€100mg230.00€500mgTo inquire1mL*10mM (DMSO)40.00€Sepantronium bromide
CAS:Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.
Formula:C20H19BrN4O3Purity:99.68% - 99.85%Color and Shape:SolidMolecular weight:443.26LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:Pale Yellow SolidMolecular weight:307.34PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Formula:C16H17N3O4SPurity:98.74% - 99.19%Color and Shape:SolidMolecular weight:347.393'-Hydroxypterostilbene
CAS:3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.Formula:C16H16O4Purity:98.25% - 99.19%Color and Shape:SolidMolecular weight:272.3BIIB021
CAS:BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).Formula:C14H15ClN6OPurity:98% - 99.82%Color and Shape:SolidMolecular weight:318.76Sapanisertib
CAS:Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.Formula:C15H15N7OPurity:99.19% - >99.99%Color and Shape:SolidMolecular weight:309.33Ref: TM-T1838
1mg40.00€2mg51.00€5mg85.00€10mg96.00€25mg160.00€50mg235.00€100mg350.00€500mg838.00€1mL*10mM (DMSO)88.00€Flavopiridol hydrochloride
CAS:Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.Formula:C21H21Cl2NO5Purity:98.87% - 99.88%Color and Shape:SolidMolecular weight:438.3Orthanilamide
CAS:Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.Formula:C6H8N2O2SPurity:99.72% - 99.96%Color and Shape:White To Pale Cream Crystalline Powder Or CrystalsMolecular weight:172.2Doramapimod HCl
CAS:Doramapimod HCl, a p38MAPK inhibitor in clinical trials for autoimmune diseases, has slow binding kinetics.Formula:C31H38ClN5O3Color and Shape:SolidMolecular weight:564.13AGN 193109
CAS:AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).Formula:C28H24O2Purity:99.87% - 99.89%Color and Shape:SolidMolecular weight:392.49Ref: TM-TQ0097
2mg95.00€5mg144.00€10mg222.00€25mg401.00€50mg620.00€100mg888.00€1mL*10mM (DMSO)152.00€MPP+ iodide
CAS:MPP+ iodide, a neurotoxin byproduct, mimics Parkinson's by killing substantia nigra neurons and affecting neuron transporters, inducing cell death.Formula:C12H12INPurity:99.49% - 99.96%Color and Shape:SolidMolecular weight:297.13GSK2578215A
CAS:GSK2578215A is a potent and selective LRRK2 kinase inhibitor.Formula:C24H18FN3O2Purity:99.57% - 99.94%Color and Shape:SolidMolecular weight:399.42Imatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormula:C29H31N7OPurity:99.42% - 99.94%Color and Shape:Off White PowderMolecular weight:493.6
