Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1424 products of "Autophagy"
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Metyrapone
CAS:<p>Metyrapone (NSC-25265) blocks steroid 11β-monooxygenase, used to diagnose Cushing's syndrome.</p>Formula:C14H14N2OPurity:99.03% - ≥95%Color and Shape:Crystals From Ether & Pentane SolidMolecular weight:226.27Myricetin
CAS:<p>Myricetin (Cannabiscetin) is a natural flavonoid and MEK1 inhibitor. Myricetin has hypoglycemic and antioxidant activities. Cost-effective and quality-assured.</p>Formula:C15H10O8Purity:97.92% - 99.85%Color and Shape:Yellow Needles From Dilute Alcohol SolidMolecular weight:318.24Retinoic acid
CAS:<p>Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.</p>Formula:C20H28O2Purity:97.21% - 99.6%Color and Shape:Yellow-Orange PowderMolecular weight:300.44Telmisartan
CAS:<p>Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.</p>Formula:C33H30N4O2Purity:99.88% - 99.97%Color and Shape:White Or Off White Crystalline PowderMolecular weight:514.62Pictilisib dimethanesulfonate
CAS:<p>Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and</p>Formula:C25H35N7O9S4Purity:99.63%Color and Shape:SolidMolecular weight:705.85Berberine chloride
CAS:<p>Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.</p>Formula:C20H18ClNO4Purity:99.47% - 99.93%Color and Shape:Yellow Crystalline PowderMolecular weight:371.8Ciclopirox
CAS:<p>Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.</p>Formula:C12H17NO2Purity:97.72% - 99.78%Color and Shape:SolidMolecular weight:207.27Vancomycin hydrochloride
CAS:<p>Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!</p>Formula:C66H76Cl3N9O24Purity:97.20% - 99.19%Color and Shape:Off White PowderMolecular weight:1485.71Ancitabine hydrochloride
CAS:<p>Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity.</p>Formula:C9H12ClN3O4Purity:99.02% - 99.37%Color and Shape:White SolidMolecular weight:261.66Irinotecan Hydrochloride
CAS:<p>Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.</p>Formula:C33H39ClN4O6Purity:98% - 99.94%Color and Shape:Yellow Crystalline PowderMolecular weight:623.14ZX-29
CAS:<p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>Formula:C23H28ClN7O3SPurity:98.32%Color and Shape:SolidMolecular weight:518.03Trimetazidine dihydrochloride
CAS:<p>Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.</p>Formula:C14H24Cl2N2O3Purity:99.58%Color and Shape:Crystalline SolidMolecular weight:339.258LG-100064
CAS:<p>LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)</p>Formula:C23H26O3Purity:98.65%Color and Shape:SolidMolecular weight:350.45Felodipine
CAS:<p>Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.</p>Formula:C18H19Cl2NO4Purity:99.91%Color and Shape:SolidMolecular weight:384.25Isoliquiritigenin
CAS:<p>Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.</p>Formula:C15H12O4Purity:97.61% - 99.44%Color and Shape:PowderMolecular weight:256.25Carvedilol phosphate hemihydrate
CAS:<p>Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.</p>Formula:C24H26N2O4·5H2O·H3O4PPurity:99.24% - 99.98%Color and Shape:SolidMolecular weight:513.49Doxorubicin hydrochloride
CAS:<p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>Formula:C27H29NO11·HClPurity:98% - 99.52%Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Molecular weight:579.99Erlotinib hydrochloride
CAS:<p>Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formula:C22H23N3O4·HClPurity:99.78% - 99.85%Color and Shape:White Or Off-White PowderMolecular weight:429.9Oxidopamine hydrobromide
CAS:<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Formula:C8H12BrNO3Purity:98.22% - 99.88%Color and Shape:Beige To Brown Fine Crystalline PowderMolecular weight:250.09Elexacaftor
CAS:<p>Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.</p>Formula:C26H34F3N7O4SPurity:98.87% - 99.87%Color and Shape:SolidMolecular weight:597.659-ING-41
CAS:<p>9-ING-41 is a glycogen synthase kinase-3 inhibitor.</p>Formula:C22H13FN2O5Purity:99.32%Color and Shape:SolidMolecular weight:404.35Aceglutamide
CAS:<p>Aceglutamide (N2-Acetylglutamine) is an acetyl derivative of the amino acid L-glutamine, used to improve memory.</p>Formula:C7H12N2O4Purity:99.56% - 99.86%Color and Shape:SolidMolecular weight:188.18Pyrazinamide
CAS:<p>Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide</p>Formula:C5H5N3OPurity:99.71% - 99.9%Color and Shape:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Molecular weight:123.11Mogamulizumab
CAS:<p>Mogamulizumab is a monoclonal antibody targeting CC chemokine receptor 4 with anticancer effects, used in ATLL and CTCL studies.</p>Purity:SDS-PAGE:97.3%;SEC-HPLC:99.4%Color and Shape:LiquidMolecular weight:146.43 kDaVitamin B3-d4
CAS:<p>Vitamin B3-d4 (Nicotinic acid-(ring-d4)) is a deuterated substitute for Niacin and can be used to track Niacin metabolism in vivo.</p>Formula:C6HD4NO2Purity:99.86%Color and Shape:SolidMolecular weight:127.13Amiodarone hydrochloride
CAS:<p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>Formula:C25H29I2NO3·HClPurity:99.82% - ≥95%Color and Shape:White To Cream Crystalline PowderMolecular weight:681.78Itraconazole
CAS:<p>Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.</p>Formula:C35H38Cl2N8O4Purity:98% - 99.90%Color and Shape:Off-White Crystalline SolidMolecular weight:705.63Lomustine
CAS:<p>Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.</p>Formula:C9H16ClN3O2Purity:98.36% - 99.44%Color and Shape:Solid SolidMolecular weight:233.7Eldelumab
CAS:<p>Eldelumab (BMS-936557) is an anti-IP-10 IgG 1 monoclonal antibody.Eldelumab has anti-inflammatory activity and is used to study rheumatoid arthritis.</p>Purity:95%Color and Shape:LiquidAcesulfame Potassium
CAS:<p>Acesulfame potassium is a non-nutritive sweetener.</p>Formula:C4H4KNO4SPurity:99.65%Color and Shape:White Solid CrystallineMolecular weight:201.24Hydroxyurea
CAS:<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Formula:CH4N2O2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:76.05Baicalin
CAS:<p>Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV</p>Formula:C21H18O11Purity:90.08% - 99.32%Color and Shape:Yellow PowderMolecular weight:446.36Glibenclamide
CAS:<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494.00Tranexamic acid
CAS:<p>Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.</p>Formula:C8H15NO2Purity:99.64% - 99.79%Color and Shape:White Crystalline PowderMolecular weight:157.21Sulfacetamide sodium monohydrate
CAS:<p>Sulfacetamide sodium monohydrate is a sulfonamide antibiotic. It has been investigated for the treatment of rosacea and pityriasis versicolor.</p>Formula:C8H9N2NaO3S·H2OPurity:99.92%Color and Shape:White Crystalline PowderMolecular weight:254.2Colistin sulfate
CAS:<p>Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.</p>Formula:C53H100N16O17SPurity:98%Color and Shape:PowderMolecular weight:1253.51Sulfanitran
CAS:<p>Sulfanitran is a sulfonamide antibiotic used in the poultry industry.</p>Formula:C14H13N3O5SPurity:98.3% - 99.60%Color and Shape:SolidMolecular weight:335.34Adapalene
CAS:<p>Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.</p>Formula:C28H28O3Purity:99.53% - 99.76%Color and Shape:White To Off-White Crystalline PowderMolecular weight:412.52MLi-2
CAS:<p>MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.</p>Formula:C21H25N5O2Purity:98.96%Color and Shape:SolidMolecular weight:379.46Loperamide hydrochloride
CAS:<p>Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.</p>Formula:C29H34Cl2N2O2Purity:99.91% - >99.99%Color and Shape:Crystals Practically Insoluble In WaterMolecular weight:513.50Spironolactone
CAS:<p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>Formula:C24H32O4SPurity:99.87%Color and Shape:White PowderMolecular weight:416.57Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Formula:C15H24N2OPurity:97.16% - >99.99%Color and Shape:SolidMolecular weight:248.36Crustecdysone
CAS:<p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>Formula:C27H44O7Purity:99.06% - 99.67%Color and Shape:Canary Yellow Fine PowderMolecular weight:480.63Paclitaxel
CAS:<p>Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.</p>Formula:C47H51NO14Purity:98% - 99.92%Color and Shape:White PowderMolecular weight:853.91Chenodeoxycholic acid
CAS:<p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>Formula:C24H40O4Purity:99.70% - 99.93%Color and Shape:White - Almost White Solid PowderMolecular weight:392.57Pemetrexed disodium
CAS:<p>Pemetrexed disodium treats lung cancer/mesothelioma; may cause moderate serum enzyme elevation, rarely acute liver injury.</p>Formula:C20H19N5Na2O6Purity:99.29% - 99.49%Color and Shape:Crystalline SolidMolecular weight:471.37Naproxen sodium
CAS:<p>Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.</p>Formula:C14H13NaO3Purity:99.68% - 99.79%Color and Shape:White PowderMolecular weight:252.24Vorinostat
CAS:<p>Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11.</p>Formula:C14H20N2O3Purity:99.47% - 99.65%Color and Shape:White Crystalline SolidMolecular weight:264.32Sulfisoxazole
CAS:<p>Sulfisoxazole: a short-acting antibacterial targeting gram-positive/negative bacteria and inhibits breast cancer exosome by affecting endothelin receptor A.</p>Formula:C11H13N3O3SPurity:99.87% - 99.98%Color and Shape:White To Cream PowderMolecular weight:267.30Niacin
CAS:<p>Niacin is a water-soluble B vitamin with antihyperlipidemic effects, found in food and converted to niacinamide for coenzyme activity.</p>Formula:C6H5NO2Purity:99.05% - 99.72%Color and Shape:White Solid PowderMolecular weight:123.11
