GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,994 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5964 products of "GPCR/G-Protein"
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8-M-PDOT
CAS:8-M-PDOT (AH-002) is an MT2 receptor agonist that inhibits MT1.8-M-PDOT has anxiolytic activity and may be used in the study of neuropathic pain.Formula:C14H19NO2Purity:99.54% - 99.54%Color and Shape:SolidMolecular weight:233.31WAY208466 dihydrochloride
CAS:WAY208466 dihydrochloride is a 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity.Formula:C17H20Cl2FN3O2SPurity:98.43% - 99.56%Color and Shape:SolidMolecular weight:420.33AHR-13268D
CAS:AHR-13268D is a new agent of antiallergic/antihistaminic.Formula:C28H29F2NNaO4Purity:98%Color and Shape:SolidMolecular weight:504.53E2508
CAS:E2508 is a selective antagonist of corticotropin-releasing factor 1 receptor.Formula:C36H47N3O7SPurity:98%Color and Shape:SolidMolecular weight:665.84FR 121196
CAS:FR 121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.Formula:C12H16FN3O3SColor and Shape:SolidMolecular weight:301.34A23887
CAS:A23887 is a potentially neuroleptic tetracyclic spiro amine that has affinity for dopamine D-2 receptors.Formula:C22H24ClNPurity:98%Color and Shape:SolidMolecular weight:337.89Altanserin hydrochloride
CAS:Altanserin hydrochloride is a 5-HT2A receptor antagonist.Formula:C22H23ClFN3O2SPurity:98%Color and Shape:SolidMolecular weight:447.95Amitifadine free base
CAS:Amitifadine (DOV-21947/EB-1010), an antidepressant SNDRI, curbs binge drinking and negative effects in animals with alcoholism-depression.Formula:C11H11Cl2NColor and Shape:SolidMolecular weight:228.12BE 2254
CAS:BE 2254 is an antagonist of central noradrenergic receptor.Formula:C19H21NO2Color and Shape:SolidMolecular weight:295.38LUF5831
CAS:LUF5831 is an agonist of adenosine A1 receptor.Formula:C15H12N4O2SColor and Shape:SolidMolecular weight:312.35Bromperidol decanoate
CAS:Bromperidol decanoate is an antipsychotic agent that is utilized for long-term maintenance treatment for schizophrenia.Formula:C31H41BrFNO3Color and Shape:SolidMolecular weight:574.56L 11204
CAS:L 11204 is an antifertility in vivo. It is an inhibitor of prostaglandin synthesis.Formula:C18H17N3OPurity:98%Color and Shape:SolidMolecular weight:291.35Hetramine
CAS:Hetramine is a synthetic pyrimidine agent that possesses antihistamine and anti anaphylactic effects.Formula:C15H20N4Purity:98%Color and Shape:SolidMolecular weight:256.35Opiranserin
CAS:Opiranserin is a development as an injectable agent for the treatment of postoperative pain.Formula:C21H34N2O5Purity:98%Color and Shape:SolidMolecular weight:394.51Fenethazine
CAS:Fenethazine is an effective antihistamine used as an antiallergic drug.Formula:C16H18N2SColor and Shape:SolidMolecular weight:270.39Bremazocine
CAS:Bremazocineis a potent opiate kappa-agonist and centrally acting analgesic.Formula:C20H29NO2Purity:98%Color and Shape:SolidMolecular weight:315.45AM6545
CAS:AM6545 is a CB1 receptor antagonist used in the study of obesity and diabetes.Formula:C26H23Cl2N5O3SPurity:97.03%Color and Shape:SolidMolecular weight:556.46CRA1000
CAS:CRA1000, a CRF1 receptor antagonist, involved in the regulation of stress response.Formula:C28H33FN4SPurity:98%Color and Shape:SolidMolecular weight:476.65Lenperone
CAS:Lenperone is a butyrophenone antipsychotic. Like other major tranquilizers, It has some alpha-adrenergic blocking action and is antiemetic.Formula:C22H23F2NO2Color and Shape:SolidMolecular weight:371.42AS1069562
CAS:AS1069562 inhibits 5-HT/NE reuptake, boosts IGF-1, FGF2 mRNA in dorsal root ganglia, spinal cord.Formula:C20H23NO5SPurity:98%Color and Shape:SolidMolecular weight:389.46Dexnafenodone Hydrochloride
CAS:Dexnafenodone Hydrochloride is an adrenergic receptor antagonist and serotonin uptake inhibitor.Formula:C20H24ClNOColor and Shape:SolidMolecular weight:329.86LY 87130
CAS:LY 87130 is a phenylethanolamine-N-methyltransferase inhibitor.Formula:C12H13NPurity:98%Color and Shape:SolidMolecular weight:171.24BAK2-66
CAS:BAK2-66 is a selective antagonist of the dopamine D3 receptor.Formula:C23H24Cl2FN3O2Purity:98%Color and Shape:SolidMolecular weight:464.36BN 52115
CAS:BN 52115, a platelet activating factor antagonist, has been found to inhibit in vivo bronchopulmonary alteration.Formula:C37H60BrNO4Purity:98%Color and Shape:SolidMolecular weight:662.78Talsupram hydrochloride
CAS:noradrenalin re-uptake inhibitorFormula:C20H26ClNSPurity:98%Color and Shape:SolidMolecular weight:347.95Brl 20596
CAS:Brl 20596 is a central dopamine antagonist in the class of anilide.Formula:C20H24ClN3O2Purity:98%Color and Shape:SolidMolecular weight:373.88Tei 6472
CAS:Tei 6472 is a more hydrophilic form of TEI-1338 which is a novel, selective lipoxygenase inhibitor.Formula:C32H39N3O5Purity:98%Color and Shape:SolidMolecular weight:545.67RGH 1756
CAS:RGH 1756 is an atypical antipsychotic with high affinity to dopamine D(3) receptors that leads to c-Fos induction in a unique pattern.Formula:C26H30N4O2SPurity:98%Color and Shape:SolidMolecular weight:462.61UNC9975
CAS:UNC9975 is a D(2) receptor agonist with antipsychotic activity used in the study of neurologic disorders such as schizophrenia.
Formula:C23H28Cl2N4O2Purity:98.78% - 98.78%Color and Shape:SolidMolecular weight:463.4Amthamine dihydrobromide
CAS:H2 agonistFormula:C6H13Br2N3SPurity:98%Color and Shape:SolidMolecular weight:319.06Benafentrine dimaleate
CAS:Benafentrine dimaleate is a platelet activating factor receptor (PAFR) antagonists and phosphodiesterase (PDE) 3/4 inhibitors.Formula:C31H35N3O11Purity:98%Color and Shape:SolidMolecular weight:625.63Flerobuterol
CAS:Flerobuterol is a potential antidepressant agent related to beta-adrenergic agonists.Formula:C12H18FNOPurity:98%Color and Shape:SolidMolecular weight:211.28LUF5981
CAS:LUF5981 is a selective agonist of human adenosine A1 receptor.Formula:C24H23N3Color and Shape:SolidMolecular weight:353.46DA 4643
CAS:DA 4643, a histamine H2-receptor antagonist, binds similarly to mifentidine at the receptor.Formula:C12H16Cl2N6SPurity:98%Color and Shape:SolidMolecular weight:347.26SDZ 205-557 hydrochloride
CAS:5-HT3/5-HT4 receptor antagonistFormula:C14H22Cl2N2O3Purity:98%Color and Shape:SolidMolecular weight:337.24CV-3988
CAS:CV-3988 is a specific antagonist of PAF-R (platelet-activating factor receptor)(Ki = 0.872 μM).Formula:C28H53N2O7PSColor and Shape:SolidMolecular weight:592.77Mequitamium iodide
CAS:Mequitamium iodide is a PAF inhibitor, curbing platelet aggregation and bronchoconstriction without blocking PAF receptors.Formula:C21H25IN2SColor and Shape:SolidMolecular weight:464.41Virodhamine trifluoroacetate
CAS:Virodhamine trifluoroacetate: full GPR55 & CB2 agonist, partial CB1 antagonist, cannabinoid receptor mixed antagonist.Formula:C24H38F3NO4Purity:98%Color and Shape:SolidMolecular weight:461.56Dihydroalprenolol, (S)-
CAS:Dihydroalprenolol, (S)- is a hydrogenated alprenolol derivative. It acts as a beta-adrenergic blocker.Formula:C15H25NO2Purity:98%Color and Shape:SolidMolecular weight:251.36ADX-10061
CAS:ADX-10061 is a dopamine D1 receptor antagonist.Formula:C19H20N2O4Color and Shape:SolidMolecular weight:340.37Gastrazole free acid
CAS:Gastrazole is a CCK2 receptor antagonist potentially. It also used for the treatment of pancreatic cancer.Formula:C34H34FN5O7Purity:98%Color and Shape:SolidMolecular weight:643.66Levomoprolol
CAS:Levomoprolol, (S)-enantiomer of the moprololis, is a beta adrenergic antagonist.Formula:C13H21NO3Purity:98%Color and Shape:SolidMolecular weight:239.31PF-04628935
CAS:PF-04628935: potent GHS-R1a antagonist/inverse agonist, IC50=4.6 nM, orally bioavailable, brain penetrant.Formula:C24H26ClN7OSPurity:98%Color and Shape:SolidMolecular weight:496.03GSK 894281
CAS:GSK 894281 is a ghrelin receptor agonist. It may produces myocardial degeneration/necrosis in rats.Formula:C24H28FN3O4SPurity:98%Color and Shape:SolidMolecular weight:473.56RP5063 Hydrochloride
CAS:RP5063 Hydrochloride is a modulator of multimodal serotonin receptors.Formula:C22H26Cl3N3O3Purity:98%Color and Shape:SolidMolecular weight:486.82Dacemazine hydrochloride
CAS:Dacemazine is a phenothiazine derivative that acts as a histamine antagonist at the H1 subtype. It was also assessed as a possible anticancer drug.Formula:C16H17ClN2OSPurity:98%Color and Shape:SolidMolecular weight:320.84SNAP 5089
CAS:α1A-adrenoceptor antagonistFormula:C36H40N4O5Purity:98%Color and Shape:SolidMolecular weight:608.73Dacopafant
CAS:Dacopafant is an antagonist of platlet activationg factor receptor.Formula:C12H11N3OSColor and Shape:SolidMolecular weight:245.3L-748328
CAS:L-748328 is a potent and selective antagonist of human beta(3)-adrenergic receptor.Formula:C23H27N3O6S2Purity:98%Color and Shape:SolidMolecular weight:505.61Dazoxiben free base
CAS:Dazoxiben is an antithrombotic agent used to reduce the formation of blood clots.Formula:C12H12N2O3Purity:98%Color and Shape:SolidMolecular weight:232.24Bamifylline Hydrochloride
CAS:Bamifylline Hydrochloride, an adenosine A1 receptor antagonist, is uesd to treat bronchiectasis and chronic obstructive pulmonary disease.Formula:C20H28ClN5O3Color and Shape:SolidMolecular weight:421.92H3R-IN-1 Hydrochloride
CAS:H3R-IN-1 Hydrochloride is an inverse agonist of histamine receptor 3( H3R ) .Formula:C19H24ClN3O3Purity:98%Color and Shape:SolidMolecular weight:377.86LY 171859
CAS:LY 171859 is an agonist of D2-receptor.Formula:C17H14O5Purity:98%Color and Shape:SolidMolecular weight:298.29Chlorazanil
CAS:Chlorazanil is a triazine-based, orally active diuretic that blocks Na+ and Cl– reabsorption in distal tubules, increases renal prostaglandin.Formula:C9H8ClN5Purity:98.89%Color and Shape:SolidMolecular weight:221.65EMDT
CAS:EMDT oxalate is a selective 5-HT6 agonist, and has antidepressant effects.Formula:C15H22N2OPurity:97.66% - 99.78%Color and Shape:SolidMolecular weight:246.35Ref: TM-T11183
1mg87.00€2mg118.00€5mg167.00€10mg202.00€25mg449.00€50mg652.00€100mg888.00€500mg1,783.00€1mL*10mM (DMSO)166.00€DR-4004
CAS:DR-4004 is a selective serotonin 5-HT7 receptor antagonist.Formula:C26H30N2OColor and Shape:SolidMolecular weight:386.53DOV-216,303 Free Base
CAS:DOV-216,303 inhibits serotonin, norepinephrine, dopamine reuptake (IC50s: 14, 20, 78 nM) with antidepressant properties.Formula:C11H11Cl2NPurity:96.7%Color and Shape:SolidMolecular weight:228.12CJ 033466
CAS:CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.Formula:C19H28ClN5OPurity:99.72%Color and Shape:SolidMolecular weight:377.91Ref: TM-T22671
1mg48.00€5mg101.00€10mg170.00€25mg270.00€50mg386.00€100mg520.00€1mL*10mM (DMSO)124.00€L 10503
CAS:L 10503 is an antifertility agent.Formula:C17H15N3OPurity:98%Color and Shape:SolidMolecular weight:277.32LEK 8841
CAS:LEK 8841 is an ergoline derivative that is a potential antipsychotic.Formula:C21H24BrN3O4SPurity:98%Color and Shape:SolidMolecular weight:494.4L 659989
CAS:L 659989 is an antagonist of the Platelet-activating factor receptor.Formula:C24H32O8SPurity:98%Color and Shape:SolidMolecular weight:480.5712(S)-hydroxy-16-Heptadecynoic Acid
CAS:The compound is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase.Formula:C17H30O3Purity:98%Color and Shape:SolidMolecular weight:282.42DuP 734
CAS:DuP 734 is a potent and selective sigma receptor antagonist, functioning as a ligand for both sigma and 5-HT2 receptors, and exhibiting weak affinity towards D2 receptors. It possesses potential antipsychotic activity, potentially devoid of the motor side effects commonly observed with neuroleptics[1][2][3].
Formula:C17H23BrFNOColor and Shape:SolidMolecular weight:356.279MRS1067
CAS:MRS1067 is an antagonist of A3 adenosine receptor.Formula:C19H16Cl2O3Color and Shape:SolidMolecular weight:363.23BGC-20-1531 free base
CAS:BGC-20-1531 (PGN 1531) free base is a selective and potent prostaglandin EP4 receptor antagonist (pKB: 7.6) that exhibits potential for migraine research.Formula:C26H24N2O6SColor and Shape:SolidMolecular weight:492.54Zometapine
CAS:Zometapine (CI 716) is an antidepressant compound that is a derivative of pyrazole and diazepine.Formula:C14H15ClN4Purity:98.87%Color and Shape:SolidMolecular weight:274.75Amibegron hydrochloride
CAS:Amibegron hydrochloride is a selective β3-adrenoceptor agonist (EC50: 3.5 nM for β-adrenoceptor in rat colon). It has anxiolytic and antidepressant activity.Formula:C22H27Cl2NO4Color and Shape:SolidMolecular weight:440.36(S)-Viloxazine Hydrochloride
CAS:(S)-Viloxazine Hydrochloride is an S-isomer and NRI used as an antidepressant.Formula:C13H20ClNO3Purity:99.95%Color and Shape:SolidMolecular weight:273.76Ref: TM-T22420
1mg35.00€5mg66.00€10mg89.00€25mg124.00€50mg172.00€100mg251.00€500mg625.00€1mL*10mM (DMSO)69.00€Octahydroisoindole
CAS:Octahydroisoindole is a natural product and a reference standard.Formula:C8H15NPurity:≥98%Color and Shape:SolidMolecular weight:125.215-HT2A receptor agonist-2
CAS:Potent 5-HT2A receptor agonist-2 targets 5-HT2A/B/C with EC50 1.7, 0.58, 0.50 nM.Formula:C20H21ClN2O3Color and Shape:SolidMolecular weight:372.85MAT2A-IN-3
CAS:MAT2A-IN-3: potent MAT2A inhibitor, hinders MTAP-deficient cancer cell growth, potential for cancer research.Formula:C24H16F5N5O3Color and Shape:SolidMolecular weight:517.41Aligeron
CAS:Aligeron is a non-selective prostaglandin (PG) antagonist that inhibits PGF2α- and PGE2-induced decreases in blood pressure in cats, and can be used to inhibitFormula:C20H24N2Purity:99.09% - >99.99%Color and Shape:SolidMolecular weight:292.42Captodiame
CAS:Captodiame is an antihistamine agent.Formula:C21H29NS2Purity:98%Color and Shape:SolidMolecular weight:359.59BAY-u 9773
CAS:BAY-u9773 is a non-selective CysLT receptor antagonist with similar IC50 for CysLT1 and CysLT2, inhibiting LT responses.Formula:C27H36O5SColor and Shape:White OilMolecular weight:472.64GW-876167
CAS:GW-876167, a 5-HT2C agonist, is used potentially for the treatment of obesity and glaucoma.Formula:C16H21N5O2Purity:98%Color and Shape:SolidMolecular weight:315.37Nebidrazine
CAS:Nebidrazine is an alpha-adrenoceptor agonist.Formula:C9H8Cl2N6Color and Shape:SolidMolecular weight:271.11EPAC 5376753
CAS:EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.Formula:C15H8Cl2N2O3SPurity:97.48%Color and Shape:SolidMolecular weight:367.21Ziprasidone mesylate trihydrate
CAS:Ziprasidone mesylate hydrate is an oral 5-HT/D2 antagonist with Ki: D2=4.8nM, 5-HT2A=0.42nM, 5-HT1A=3.4nM in rats.Formula:C22H31ClN4O7S2Color and Shape:SolidMolecular weight:563.08Impromidine
CAS:Impromidine is a highly potent and specific agonist of the histamine H2 receptor.Formula:C14H23N7SPurity:98%Color and Shape:SolidMolecular weight:321.44Povafonidine
CAS:Povafonidine (PGE-6201204), an alpha-2 adrenoreceptor agonist, constricts vessels, reduces congestion for nasal research.Formula:C11H13N5Color and Shape:SolidMolecular weight:215.25Tilisolol HCl
CAS:Tilisolol, a nonselective beta-blocker, dilates dog coronary arteries via ATP-sensitive K(+) channels.Formula:C17H25ClN2O3Purity:98%Color and Shape:SolidMolecular weight:340.85Vapitadine dihydrochloride
CAS:Vapitadine dihydrochloride(R-129160 2HCl) is a novel, potent, selective and non-sedating compound with inhibitory effects on histamine H1.Formula:C17H22Cl2N4OPurity:98.28% - 99.30%Color and Shape:SolidMolecular weight:369.29ATL-801
CAS:ATL-801 is anselective antagonist of A2B receptor with herapeutic activity for colitis.Formula:C24H25N7O3Color and Shape:SolidMolecular weight:459.5PF-3246799
CAS:PF-3246799 is an effective and selective agonist of the 5-HT2C receptor.Formula:C15H17N3Purity:98%Color and Shape:SolidMolecular weight:239.32LY 219057
CAS:LY 219057 is a potent, competitive, and specific antagonist of CCK receptor on the exocrine pancreas.Formula:C23H17ClF3N3OSColor and Shape:SolidMolecular weight:475.91Tulopafant
CAS:Tulopafant (RP 59227) is a potent platelet-activating factor (PAF) antagonist that increases capillary patency and prolongs allograft heart survival.Formula:C25H19N3O2SPurity:99.38%Color and Shape:SolidMolecular weight:425.5Naronapride
CAS:Naronapride (ATI-7505) is a potent agonist of the prokinetic 5-HT4receptor and can be used to study gastrointestinal disorders.Formula:C27H41ClN4O5Color and Shape:SolidMolecular weight:537.09EP2 receptor antagonist-1
CAS:EP2 receptor antagonist-1: reversible, potent, depends on agonist; anti-inflammatory.Formula:C24H22N4O5Color and Shape:SolidMolecular weight:446.46NAEPA
CAS:NAEPA, an LPA mimetic, is a selective agonist of the lysophosphatidic acid-1 (LPA1) receptor.Formula:C20H40NO5PPurity:98%Color and Shape:SolidMolecular weight:405.51Zicronapine
CAS:Zicronapine (LU 31-130), an atypical antipsychotic with monoaminergic action, targets dopamine D1/D2 and serotonin 5HT2A.Formula:C22H27ClN2Color and Shape:SolidMolecular weight:354.92SKF-75670 Hydrobromide
CAS:SKF-75670 hydrobromide is an atypical D1DR (dopamine receptor) agonist. It displays agonist activity in vivo and antagonist activity in vitro.Formula:C17H20BrNO2Color and Shape:SolidMolecular weight:350.25Isoproterenol-d7 HCl
CAS:Isoproterenol-d7: internal standard for GC/LC-MS. β1-/β2-AR agonist, not for β3. Lowers blood pressure, tackles bradydysrhythmias, asthma.Formula:C11H18ClNO3Color and Shape:SolidMolecular weight:254.76GCGR antagonist 2
CAS:Orally active GCGR antagonist 2, a furan-2-carbohydrazide, binds hGluR at 2.3 nM. Blocks glucagon, inhibits rat receptor at 0.43 nM.Formula:C28H26N4O2Color and Shape:SolidMolecular weight:450.53Ko-3290
CAS:Ko-3290 is a cardioselective antagonist of β-adrenoceptors known for its antilipolytic effects in animals.Formula:C19H25N3O3Purity:98%Color and Shape:SolidMolecular weight:343.42S-5751
CAS:S-5751, a prostanoid DP (DP1) antagonist, is used potentially for the treatment of bronchial asthma.Formula:C25H31NO4SColor and Shape:SolidMolecular weight:441.58Imiloxan hydrochloride
CAS:Imiloxan hydrochloride is an α2-adrenoceptor antagonist.Formula:C14H17ClN2O2Purity:98%Color and Shape:SolidMolecular weight:280.75OUP-186
CAS:OUP-186 is a selective H3 receptor antagonist that suppresses breast cancer cell growth with an IC50 of ~50 μM and induces apoptosis.Formula:C19H30ClN3SColor and Shape:SolidMolecular weight:367.98Gastrazole disodium
CAS:Gastrazole, a CCK2 receptor antagonist, is used potentially for the treatment of pancreatic cancer.Formula:C34H34FN5Na2O7Color and Shape:SolidMolecular weight:689.652Methylcarbamyl PAF C-16
CAS:Methylcarbamyl PAF C-16 (Carbamyl-PAF) is a PAF analog with PAF agonistic properties, activating inflammation in pregnancy tissues and promoting preterm birth.Formula:C26H55N2O7PColor and Shape:SolidMolecular weight:538.7SC 51089 free base
CAS:SC 51089 free base is a selective antagonist of the prostaglandin E2 EP1 receptor, demonstrating neuroprotective activity.Formula:C22H19ClN4O3Color and Shape:SolidMolecular weight:422.86
