GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(3,003 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5963 products of "GPCR/G-Protein"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
LH 21
CAS:LH-21, a strong CB1 receptor antagonist, curbs eating and lessens weight gain in obese rats.Formula:C20H20Cl3N3Color and Shape:SolidMolecular weight:408.75ReN-1869 hydrochloride
CAS:ReN 1869 hydrochloride is a novel, selective antagonist of histamine H1 receptor.Formula:C24H28ClNO2Purity:98%Color and Shape:SolidMolecular weight:397.94Lenperone HCl
CAS:Lenperone HCl is a dopamine antagonist and an antipsychotic agent.Formula:C22H24ClF2NO2Purity:98%Color and Shape:SolidMolecular weight:407.88Sch412348
CAS:Sch412348: potent A2A receptor antagonist, Ki=0.6 nM, >1000-fold selectivity vs. other adenosine receptors.Formula:C22H21F2N9OPurity:98%Color and Shape:SolidMolecular weight:465.46ChemR23-IN-2
CAS:ChemR23-IN-2 is a potent, orally active inhibitor of ChemR23 (IC50: 3.2 nM).Formula:C29H26N4O5Color and Shape:SolidMolecular weight:510.54Org-12962 hydrochloride
CAS:Org-12962 hydrochloride is a 5-HT2C receptor agonist.Formula:C10H12Cl2F3N3Purity:98%Color and Shape:SolidMolecular weight:302.12Pruvanserin hydrochloride
CAS:Pruvanserin hydrochloride (EMD 281014 HCl) is a selective 5-HT2A receptor antagonist, inhibits GTP-gamma-S accumulation and alleviates tactile allodynia.Formula:C22H22ClFN4OPurity:99.6%Color and Shape:SolidMolecular weight:412.89(-)-GSK598809
CAS:(-)-GSK598809 is an isomer of GSK598809 that is a potent and selective antagonist of dopamine D3 Receptor.Formula:C22H23F4N5OSPurity:98%Color and Shape:SolidMolecular weight:481.51Butanserin
CAS:Butanserin is a 5-hydroxytryptamine S2-antagonist.Formula:C24H26FN3O3Purity:98%Color and Shape:SolidMolecular weight:423.48NIDA 41020
CAS:NIDA 41020 is a CB1 receptor antagonist.Formula:C23H24Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:459.37LY 334370 hydrochloride
CAS:5-HT1F receptor agonistFormula:C21H23ClFN3OPurity:98%Color and Shape:SolidMolecular weight:387.88AS19
CAS:AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM).Formula:C18H25N3Purity:98%Color and Shape:SolidMolecular weight:283.41CM398
CAS:CM398, a sigma-2 receptor selective ligand (Ki=0.43 nM), also binds dopamine and serotonin transporters, shows anti-inflammatory analgesic effects.Formula:C23H29N3O3Color and Shape:SolidMolecular weight:395.49LASSBio-1359
CAS:LASSBio-1359 is an adenosine receptor agonist. It acts by inducing relaxation of the corpus cavernosum. It also acts as a novel selective phosphodiesterase.Formula:C17H18N2O3Purity:98%Color and Shape:SolidMolecular weight:298.34TP-680
CAS:TP-680 is a antagonist of cholecystokininA receptor.Formula:C35H33N5O4SPurity:98%Color and Shape:SolidMolecular weight:619.73Methyldopa hydrochloride
CAS:L-(-)-α-Methyldopa HCl: alpha-adrenergic agonist, antihypertensive, inhibits DOPA decarboxylase.Formula:C10H14ClNO4Purity:98%Color and Shape:SolidMolecular weight:247.68CGP 25454A
CAS:CGP 25454A is a novel and selective antagonist of the presynaptic dopamine autoreceptor.Formula:C15H21Cl2N3O2Color and Shape:SolidMolecular weight:346.25R-SKF-38393A HCl
CAS:R(+)-SKF-38393A is a D1 dopamine receptor agonist and also is a more active enantiomer of (±)-SKF-38393A.Formula:C16H18ClNO2Purity:98%Color and Shape:SolidMolecular weight:291.77Org-10490
CAS:Org-10490 is an dopamine D1 receptor and dopamine D2 receptor antagonist, and treatment for psychiatric disease.Formula:C17H19NOPurity:98%Color and Shape:SolidMolecular weight:253.34SNT-207707
CAS:SNT-207707 is a potent, selective and orally active antagonist of melanocortin MC-4 receptor(IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor).Formula:C32H44ClN5OPurity:98%Color and Shape:SolidMolecular weight:550.18BX 667
CAS:BX 667, a P2Y12 antagonist, inhibits ADP-induced platelet clumping in humans, dogs, rats with IC50s: 97, 317, 3000 nM.Formula:C29H38N4O9Purity:98%Color and Shape:SolidMolecular weight:586.63SDZ 21009
CAS:β-adrenoceptor and 5-HT1A/1B receptor antagonistFormula:C19H28N2O4Purity:98%Color and Shape:SolidMolecular weight:348.44Alniditan dihydrochloride
CAS:Alniditan dihydrochloride is a potent 5-HT1D agonist and migraine-abortive agent.Formula:C17H28Cl2N4OColor and Shape:SolidMolecular weight:375.34AM-6538
CAS:AM6538: long-acting, high-affinity CB antagonist similar to rimonabant, useful for studying cannabinoid agonists.Formula:C26H25Cl2N5O4Color and Shape:SolidMolecular weight:542.41SF 11
CAS:SF 11 is a potent and brain penetrant neuropeptide Y Y2 receptor antagonist with IC50 of 199 nM. Antidepressant-like activityFormula:C27H30N2O2SPurity:99.51%Color and Shape:SolidMolecular weight:446.6Tesofensine
CAS:Tesofensine, a serotonin–noradrenaline–dopamine reuptake inhibitor, is used potentially for the treatment of obesity.Formula:C17H23Cl2NOPurity:98%Color and Shape:SolidMolecular weight:328.28A1AR antagonist 4
CAS:Compound 22: A1AR antagonist, pIC50 5.51, pKi 6.29, potent and selective.Formula:C23H25N3O2Color and Shape:SolidMolecular weight:375.46Mivazerol
CAS:Mivazerol is an alpha 2-adrenoceptor agonist.Formula:C11H11N3O2Color and Shape:SolidMolecular weight:217.22Ulimorelin
CAS:Ulimorelin, ghrelin receptor agonist (EC50: 29 nM, Ki: 16 nM), is a prokinetic and vasorelaxant via α1-adrenoceptor antagonism.Formula:C30H39FN4O4Purity:98%Color and Shape:SolidMolecular weight:538.65MJ 15
CAS:MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.Formula:C23H17Cl3N4OPurity:99.63%Color and Shape:SolidMolecular weight:471.775-Methylurapidil
CAS:5-Methylurapidil is an alpha1A-adrenoceptor antagonist.Formula:C21H31N5O3Purity:98%Color and Shape:SolidMolecular weight:401.5AZ8838
CAS:AZ8838 is an effective, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pK i of 6.4 for hPAR2 [1].
Formula:C13H15FN2OColor and Shape:SolidMolecular weight:234.27KW-8232 free base
CAS:KW-8232 free base can reduces the biosynthesis of PGE2, is an anti-osteoporotic agent.Formula:C36H37ClN4O3Purity:98%Color and Shape:SolidMolecular weight:609.16Butopamine
CAS:Butopamine differs from dobutamine in location of only one hydroxyl group, but is no longer a catecholamine.Formula:C18H23NO3Color and Shape:SolidMolecular weight:301.38PSB 11 hydrochloride
CAS:PSB 11 hydrochloride is a human adenosine A3 receptor antagonist.Formula:C16H18ClN5OPurity:98%Color and Shape:SolidMolecular weight:331.8Ronactolol
CAS:Ronactolol is an aminopropanol derivative with beta-adrenoreceptor blocking activity.Formula:C20H26N2O4Color and Shape:SolidMolecular weight:358.43DR4485 hydrochloride
CAS:5-HT7 antagonistFormula:C26H29Cl3N2OPurity:98%Color and Shape:SolidMolecular weight:491.88RS 39604
CAS:potent and selective 5-HT4 antagonistFormula:C26H37Cl2N3O6SPurity:98%Color and Shape:SolidMolecular weight:590.56BAY 1214784
CAS:BAY 1214784: potent, oral hGnRH-R antagonist, reduces LH levels, low variability, good tolerance, may research uterine fibroids.Formula:C29H26ClF4N3O5S2Purity:100% - 99.77%Color and Shape:SolidMolecular weight:672.11CP-376395 HCl
CAS:CP 376395 hydrochloride is a potent and selective CRF-RI receptor antagonist.Formula:C21H31ClN2OColor and Shape:SolidMolecular weight:362.94Org41841
CAS:Org41841 is an agonist of luteinising hormone/chorionic gonadotropin receptor and thyroid stimulating hormone receptor and can be used to study hyperthyroidism.Formula:C19H22N4O2S2Purity:99.46% - 99.92%Color and Shape:SolidMolecular weight:402.53SSTR5 antagonist 2
CAS:SSTR5 antagonist 2: potent, orally active, selective SSTR5 inhibitor, may treat Type 2 diabetes.Formula:C32H35FN2O5Purity:98%Color and Shape:SolidMolecular weight:546.63Ksg 504
CAS:Ksg 504 has superior selectivity and affinity to CCK-A receptors and derived from proglumide.Formula:C31H49N5O8SColor and Shape:SolidMolecular weight:651.81(±)-Tazifylline
CAS:(±)-Tazifylline is a selective and long-acting antagonist of histamine H1 receptor.Formula:C23H32N6O3SPurity:99.54%Color and Shape:SolidMolecular weight:472.6Ref: TM-T10000
1mg148.00€5mg284.00€10mg411.00€25mg645.00€50mg867.00€100mg1,121.00€1mL*10mM (DMSO)369.00€Levobetaxolol
CAS:Levobetaxolol (AL-1577A/Betaxon) is a beta-blocker for ocular hypertension and glaucoma.Formula:C18H29NO3Purity:98%Color and Shape:SolidMolecular weight:307.43Ethiazide
CAS:Ethiazide is a benzothiadiazine sulfonamide derivative belonging to the class of the thiazide diuretics.Formula:C9H12ClN3O4S2Color and Shape:SolidMolecular weight:325.79GSK3004774
CAS:GSK3004774 is a nonabsorbable agonist of CaSR (pEC50: 7.3, 6.6, and 6.5 for human, mouse, and rat CaSR). GSK3004774 shows an EC50 of 50 nM for human CaSR.Formula:C32H40N4O3Purity:98%Color and Shape:SolidMolecular weight:528.68XCC
CAS:XCC is an Adenosine receptor antagonist.Formula:C19H22N4O5Purity:98%Color and Shape:SolidMolecular weight:386.4Adenosine receptor antagonist 3
CAS:Adenosine receptor antagonist 3 has the potential for cancer disease research which is a potent adenosine receptor antagonist [1].Formula:C16H14N6SColor and Shape:SolidMolecular weight:322.39DA 4626
CAS:DA 4626 is an H2-receptor antagonist with KB values akin to those in standard assays.Formula:C14H18N4Purity:98%Color and Shape:SolidMolecular weight:242.32ZCZ011
CAS:ZCZ011 enhances CB1 receptor effects, crosses blood-brain barrier, and potentiates cannabimimetic behaviors in mice.Formula:C21H18N2O2SPurity:98%Color and Shape:SolidMolecular weight:362.44YM-17690
CAS:YM-17690 is a non-analogous leukotriene agonist.Formula:C28H29NO7Purity:98%Color and Shape:SolidMolecular weight:491.53Seliforant
CAS:Seliforant is a histamine H4 receptor antagonist.Formula:C12H21N5Purity:98%Color and Shape:SolidMolecular weight:235.33S1P1 Agonist III
CAS:S1P1 Agonist III is an orally active S1P1 receptor agonist (EC₅₀ = 18 nM) with applications in inflammation, immunology, and receptor signaling studies.Formula:C21H16F3N3O3Purity:99.08%Color and Shape:SolidMolecular weight:415.37Guanfacine
CAS:Guanfacine is a selective agonist of the α2A receptor.Formula:C9H9Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:246.09PF 10040
CAS:PF 10040 is an antagonist of platelet activating factor (PAF).Formula:C20H24ClNO2Color and Shape:SolidMolecular weight:345.86HEAT hydrochloride
CAS:HEAT hydrochloride is an α1-adrenoceptor antagonist.Formula:C19H22ClNO2Purity:98%Color and Shape:SolidMolecular weight:331.84CAD031
CAS:CAD031, a more active derivative of the Alzheimer's disease (AD) targeting agent J147, exhibits neuroprotective and memory-enhancing properties.Formula:C18H14F6N2O2Color and Shape:SolidMolecular weight:404.31Arnolol
CAS:Arnolol, a beta blocker, slows heart rate, reduces force of beats, lowers blood pressure, and enhances blood flow.Formula:C14H23NO3Color and Shape:SolidMolecular weight:253.34Acetophenazine
CAS:Acetophenazine is an anxiolytic compound that is used in the study of depression.Formula:C23H29N3O2SPurity:99.30%Color and Shape:SoildMolecular weight:411.56Denopamine
CAS:Denopamine is an agonist of 1-Adrenoceptor.Formula:C18H23NO4Color and Shape:SolidMolecular weight:317.38J-2156
CAS:J-2156, a potent SST4 agonist, has ED50s of 3.7 mg/kg for allodynia and 8.0 mg/kg for hyperalgesia in rats; IC50s are 0.05/0.07 nM in human/rat receptors.Formula:C24H28N4O4SPurity:98%Color and Shape:SolidMolecular weight:468.57MA-2029
CAS:MA-2029: selective motilin receptor antagonist (IC50=4.9 nM), could aid in gastrointestinal motility disorders.Formula:C31H45FN4O4Purity:98%Color and Shape:SolidMolecular weight:556.71SEP-363856
CAS:SEP-363856, a non-D2/5-HT2A, orally active CNS psychotropic may treat schizophrenia.Formula:C9H13NOSPurity:98%Color and Shape:SolidMolecular weight:183.27Ro 04-6790
CAS:Ro 04-6790 is a 5-HT6 receptor antagonist.Formula:C12H16N6O2SPurity:98%Color and Shape:SolidMolecular weight:308.36Fertirelin acetate
CAS:Fertirelin acetate is a gonadotropin-releasing hormone (GnRH) agonist.Formula:C55H74N16O13Color and Shape:SolidMolecular weight:1167.29Adentri
CAS:Adentri is a novel antagonist of adenosine A1 receptor with unique diuretic activity.Formula:C18H24N4O3Purity:98%Color and Shape:SolidMolecular weight:344.41Lubabegron
CAS:Lubabegron(LY488756) is used as an agonist of β3-adrenoreceptor in veterinary.Formula:C29H29N3O3SColor and Shape:SolidMolecular weight:499.625-trans-Prostaglandin E2
CAS:5-trans-PGE2 speeds up fibrinolysis, boosts tissue-PA mediated plasminogen activation, and blocks platelet clumping in human PRP.Formula:C20H32O5Color and Shape:SolidMolecular weight:352.47JTC-017
CAS:JTC-017 is an antagonist of Corticotropin-releasing hormone receptor 1.Formula:C20H25Cl2N3O5SColor and Shape:SolidMolecular weight:490.4Oxypertine
CAS:Oxypertine, an indole-derived antipsychotic, treats psychoses like mania, schizophrenia, and severe anxiety, akin to chlorpromazine.Formula:C23H29N3O2Color and Shape:SolidMolecular weight:379.5L659989
CAS:L659989 is an antagonist of PAF receptor.Formula:C24H32O8SColor and Shape:SolidMolecular weight:480.57BN 52111
CAS:BN 52111 is a platelet activating factor antagonist.Formula:C33H58BrNO4Purity:98%Color and Shape:SolidMolecular weight:612.734hBChE-IN-2
CAS:hBChE-IN-2 is a BChE inhibitor and CB2R agonist with neuroprotective activity for the study of Alzheimer's disease-like neurological disorders.Formula:C27H36N4O3Purity:99.60% - 99.83%Color and Shape:SoildMolecular weight:464.6TCV-309 chloride
CAS:TCV-309 chloride is an antagonist of platelet activating factor (PAF).Formula:C30H34BrClN4O4Purity:98%Color and Shape:SolidMolecular weight:629.97SB-737050A
CAS:SB-737050A, a 5-HT antagonist, is used potentially for the treatment of schizophrenia.Formula:C22H23ClN2O3S2Color and Shape:SolidMolecular weight:463.01GBR 12783
CAS:GBR 12783 enhances memory, boosts rat hippocampal acetylcholine, and is a potent dopamine uptake inhibitor with IC50s of 1.8/1.2 nM in rats/mice.Formula:C28H32N2OPurity:98%Color and Shape:SolidMolecular weight:412.57Sulfisoxazole diethanolamine
CAS:Sulfisoxazole diethanolamine: a sulfonamide antibacterial, endothelin receptors A and B antagonist, inhibits breast cancer exosomes.Formula:C15H24N4O5SColor and Shape:SolidMolecular weight:372.44Isoetharine
CAS:Isoetharine is a selective agonist of β2-adrenergic receptor used as a bronchodilator for emphysema, bronchitis, and asthma.Formula:C13H21NO3Color and Shape:SolidMolecular weight:239.31Ro 63-0563
CAS:Ro 63-0563 is a potent, 5-HT6 receptors selective antagonist.Formula:C13H17N5O2SPurity:98%Color and Shape:SolidMolecular weight:307.37ETA antagonist 1
CAS:ETA antagonist 1 is an antagonist of ETA selective (IC50 of 0.08 μM).Formula:C20H25N3O3SPurity:98%Color and Shape:SolidMolecular weight:387.5Mocravimod
CAS:Mocravimod: S1P1 receptor agonist, reduces atherosclerosis in mice. KRP-203 mitigates rat heart disease, extends graft survival.Formula:C24H26ClNO3SPurity:98%Color and Shape:SolidMolecular weight:443.99(S)-V-0219
(S)-V-0219: oral, GLP-1R PAM, boosts calcium in hGLP-1R HEK cells, lowers glucose, curbs hunger in mice.Formula:C20H25F3N4O2Color and Shape:SolidMolecular weight:410.43Zolertine HCl
CAS:Zolertine HCl is an antagonist of alpha-Adrenoceptor.Formula:C13H19ClN6Purity:98%Color and Shape:SolidMolecular weight:294.78Cianergoline
CAS:Cianergoline is a dopaminergic agonist.Formula:C19H22N4OPurity:98%Color and Shape:SolidMolecular weight:322.4CCG-273220
CAS:CCG-273220 covalently inhibits GRK5 at Cys474 with 220 nM IC50; more selective over GRK2.Formula:C26H24ClFN4O3Color and Shape:SolidMolecular weight:494.95VUF14862
CAS:VUF14862 is a robust and fatigue-resistant photoswitchable GPCR antagonist.Formula:C26H32N4O2Color and Shape:SolidMolecular weight:432.56Imnopitant
CAS:Imnopitant is an antagonist of the NK1 receptor [1].Formula:C28H28F6N4OColor and Shape:SolidMolecular weight:550.54(R)-Praziquantel
CAS:(R)-Praziquantel is an active enantiomer of praziquantel.Formula:C19H24N2O2Purity:98%Color and Shape:SolidMolecular weight:312.41ST-836
CAS:ST-836 is a dopamine receptor ligand; Antiparkinsonian agent .Formula:C23H34N4OSPurity:98%Color and Shape:SolidMolecular weight:414.61CIA-1 hcl(452087-38-6 Free base)
CAS:CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety ofFormula:C17H20ClN3O2SPurity:99.02%Color and Shape:SolidMolecular weight:365.88Cirazoline (free base)
CAS:Cirazoline: full α1A agonist, partial α1B/D, nonselective α2 antagonist; potential vasoconstrictor.Formula:C13H16N2OColor and Shape:SolidMolecular weight:216.28Q8 hydrochloride
CAS:Q8 is an antagonist of cysteinyl leukotreine receptor. Q8 inhibits VEGF-independent angiogenesis.Formula:C17H14ClNO2Purity:98%Color and Shape:SolidMolecular weight:299.75GSK-269984A
CAS:GSK-269984A is an antagonist of Prostaglandin E2 Receptor 1 (EP1) (pIC50: 7.9).Formula:C20H14Cl2FNNaO3Purity:98%Color and Shape:SolidMolecular weight:429.22AUY-954 free base
CAS:AUY-954 is a selective S1P(1) modulator reducing EAN inflammation and demyelination in rats.Formula:C25H20F3NO2SColor and Shape:SolidMolecular weight:455.49ZD 7114 hydrochloride
CAS:β3-adrenoceptor agonistFormula:C22H31ClN2O6Purity:98%Color and Shape:SolidMolecular weight:454.94PNU-96415E
CAS:dopamine D4 and serotonergic 5-HT2A receptor antagonistFormula:C21H27Cl2FN2OPurity:98%Color and Shape:SolidMolecular weight:413.36Paltusotine HCl
CAS:Paltusotine, also known as CRN00808, is a somatostatin receptor agonist.Formula:C27H24Cl2F2N4OColor and Shape:SolidMolecular weight:529.41Adriforant hydrochloride
CAS:Adriforant hydrochloride is an antagonist of histamine H4 receptor.Formula:C13H25Cl3N6Purity:98%Color and Shape:SolidMolecular weight:371.74TMPPAA
CAS:TMPPAA is an allosteric agonist of 5-HT3 receptor.Formula:C15H21NO2Purity:98%Color and Shape:SolidMolecular weight:247.33
