GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 18 more subcategories

Found 5378 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

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Eledoisin
CAS:
- 69-25-0
Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family
Formula:C₅₄H₈₅N₁₃O₁₅S
Purity:98%
Color and Shape:Solid
Molecular weight:1188.4
Ref: TM-TP1177
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Neurokinin A(4-10)
CAS:
- 97559-35-8
Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .
Formula:C₃₄H₅₄N₈O₁₀S
Purity:98%
Color and Shape:Solid
Molecular weight:766.91
Ref: TM-T7559
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BIMU 8
CAS:
- 134296-40-5
BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.
Formula:C₁₉H₂₇ClN₄O₂
Purity:99.87%
Color and Shape:Solid
Molecular weight:378.9
Ref: TM-T21946
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GLP-1R Agonist DMB
CAS:
- 281209-71-0
GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).
Formula:C₁₃H₁₅Cl₂N₃O₂S
Purity:99.52%
Color and Shape:Solid
Molecular weight:348.25
Ref: TM-T36579
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S1R agonist 2 hydrochloride
Compound 8b hydrochloride, a selective S1R agonist, exhibits affinity with K i s of 1.1 nM for S1R and 88 nM for S2R.
Formula:C₂₁H₂₈ClNO
Purity:98%
Color and Shape:Solid
Molecular weight:345.91
Ref: TM-T78087
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SLB1122168 formic
SLB1122168 is a potent inhibitor of Spns2-mediated sphingosine-1-phosphate (S1P) release, exhibiting an IC50 value of 94 nM [1].
Formula:C₂₃H₃₇N₃O₃
Purity:98%
Color and Shape:Solid
Molecular weight:403.56
Ref: TM-T78160
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Oxmetidine
CAS:
- 72830-39-8
Oxmetidine (SKF 92994) is an H2R antagonist that inhibits transmembrane calcium flux in the cardiovascular system and is used in the study of duodenal ulcers.
Formula:C₁₉H₂₁N₅O₃S
Purity:99.67%
Color and Shape:Solid
Molecular weight:399.47
Ref: TM-T68122
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Setmelanotide
CAS:
- 920014-72-8
Setmelanotide (BIM-22493) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
Formula:C₄₉H₆₈N₁₈O₉S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1117.31
Ref: TM-T12882
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Galantide acetate
Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P.
Formula:C₁₀₆H₁₅₅N₂₅O₂₈S
Purity:97.8% - 97.91%
Color and Shape:Solid
Molecular weight:2259.58
Ref: TM-T15368L
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L-796,778
CAS:
- 217480-25-6
L-796,778 is an SST3 agonist and a selective ligand of SST3, which can increase the level of cAMP in the body.
Formula:C₂₉H₄₀N₆O₇
Purity:96.20%
Color and Shape:Solid
Molecular weight:584.66
Ref: TM-T32511
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p-MPPF
CAS:
- 155204-26-5
p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.
Formula:C₂₅H₂₇FN₄O₂
Purity:99.92%
Color and Shape:Solid
Molecular weight:434.51
Ref: TM-T69750L
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N-Nitroso Atenolol
CAS:
- 134720-04-0
N-Nitroso Atenolol is a derivative of Atenolol. At concentrations ranging from 0.1 to 1 mM, it induces DNA fragmentation in rat hepatocytes.
Formula:C₁₄H₂₁N₃O₄
Color and Shape:Solid
Molecular weight:295.33
Ref: TM-T203130
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(±)-9-Nor-9α-hydroxy Hexahydrocannabinol
CAS:
- 56469-26-2
(±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-structured compound that exhibits potent cannabinoid-like activity in both dogs and mice.
Formula:C₂₀H₃₀O₃
Color and Shape:Solid
Molecular weight:318.45
Ref: TM-T203604
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CB2 receptor agonist 9
CAS:
- 2374894-21-8
CB2 receptor agonist 9 (Compound 33) is an orally active agonist of cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. It inhibits the expression of TNF-α, IL-1β, and IL-6, demonstrating anti-inflammatory activity in a DSS-induced acute colitis model in mice.
Formula:C₁₆H₂₃N₃O₂S
Color and Shape:Solid
Molecular weight:321.44
Ref: TM-T203517
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SBI-810
CAS:
- 1849603-79-7
SBI-810 is a functional selective β-arrestin-biased allosteric modulator of the neurotensin receptor 1 (NTSR1). In the presence of the endogenous ligand neurotensin (NT), SBI-810 regulates NTSR1 signaling through a G protein-specific mechanism. It fully antagonizes NT-induced Gq activation and partially antagonizes NT-induced Gi1 activation, allowing NTSR1 to activate GoA and G12.
Formula:C₂₇H₃₄N₄O₂
Color and Shape:Solid
Molecular weight:446.59
Ref: TM-T203513
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δ8-THC acetate
CAS:
- 23050-54-6
Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive cannabinoid that binds to the cannabinoid receptor 1 (CB1 receptor) and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory effects. It may also offer neuroprotective benefits and has potential applications in research on anxiety and depression.
Formula:C₂₃H₃₂O₃
Color and Shape:Solid
Molecular weight:356.5
Ref: TM-T203037
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Methamnetamine hydrochloride
CAS:
- 2748623-12-1
Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.
Formula:C₁₄H₁₈ClN
Color and Shape:Solid
Molecular weight:235.75
Ref: TM-T203312
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AD353
AD353 is a selective sigma-1 receptor ligand. It demonstrates high efficacy in models of capsaicin-induced allodynia and PGE2-induced mechanical hyperalgesia. Additionally, AD353 exhibits favorable pharmacokinetic properties.
Formula:C₂₃H₃₀N₂O₂
Color and Shape:Solid
Molecular weight:366.5
Ref: TM-T203662
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PF-4363467
CAS:
- 2040055-84-1
PF-4363467 is a dopamine D3/D2 receptor antagonist that reduces opioid-seeking behavior without the side effects associated with D2 receptors. It has a Ki value of 3.1 nM for D3R and 692 nM for D2R.
Formula:C₂₂H₃₀N₂O₃S
Color and Shape:Solid
Molecular weight:402.55
Ref: TM-T203495
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CAY10509
CAS:
- 1245699-47-1
CAY10509 is a PGF2α analogue and acts as an FP receptor inhibitor with an IC50 of 30 nM. It shows potential for use in studying the physiological regulatory mechanisms related to prostaglandins.
Formula:C₂₃H₃₅FO₅S
Color and Shape:Solid
Molecular weight:442.58
Ref: TM-T203384
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Pafenolol
CAS:
- 75949-61-0
Pafenolol is a P-glycoprotein modulator with a Ki value of 5.5 µM. pafenolol is an orally available and selective beta-adrenergic receptor antagonist.
Formula:C₁₈H₃₁N₃O₃
Purity:98.33%
Color and Shape:Solid
Molecular weight:337.46
Ref: TM-T68124
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Arotinolol hydrochloride
CAS:
- 68377-91-3
Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.
Formula:C₁₅H₂₂ClN₃O₂S₃
Purity:99.84%
Color and Shape:Solid
Molecular weight:408
Ref: TM-T30140
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(Leu31,Pro34)-Peptide YY (human) (TFA)
"(Leu31,Pro34)-Peptide YY (human) (TFA) is the trifluoroacetic acid (TFA) form of (Leu31,Pro34)-Peptide YY (human), a derivative of Peptide YY that acts as a
Formula:C₁₉₅H₂₉₆N₅₄O₅₆·xC₂HF₃O₂
Purity:98%
Color and Shape:Solid
Molecular weight:4292.75 (free base)
Ref: TM-T80087
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Mibenratide TFA
Mibenratide TFA, a small cyclic peptide, functions as an adrenergic β1 receptor antagonist and has potential applications in heart failure research [1].
Purity:98%
Color and Shape:Odour Solid
Ref: TM-T81798
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Galanin-Like Peptide (rat)
CAS:
- 245114-97-0
Galanin-Like Peptide (rat), a neuropeptide comprising 60 amino acids, plays a crucial role in regulating feeding, body weight, and energy metabolism [1].
Formula:C₂₈₈H₄₆₁N₈₇O₈₃S
Purity:98%
Color and Shape:Solid
Molecular weight:6502.34
Ref: TM-T80146
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TCMCB07
CAS:
- 1456699-27-6
TCMCB07, a cyclic nonapeptide, serves as an orally active, brain-penetrant antagonist of the melanocortin receptor 4 (MC4R), with significant implications in
Formula:C₆₃H₈₇N₁₅O₁₁
Purity:98%
Color and Shape:Solid
Molecular weight:1230.46
Ref: TM-T80540
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LHRH
CAS:
- 35263-73-1
Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and has
Formula:C₅₅H₇₄N₁₆O₁₄
Purity:98%
Color and Shape:Solid
Molecular weight:1183.27
Ref: TM-T80116
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CB2R agonist 3
CB2R agonist 3, a potent activator of cannabinoid receptor 2 (CB2R), exhibits an EC50 value of 0.37μM, indicative of its significant role in the immune system [
Purity:98%
Color and Shape:Odour Solid
Ref: TM-T82769
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FGH31
FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1].
Formula:C₃₃H₃₆N₄O₂
Purity:98%
Color and Shape:Solid
Molecular weight:520.66
Ref: TM-T79312
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MRS7925
MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosis
Formula:C₂₀H₂₆IN₅O₃
Purity:98%
Color and Shape:Solid
Molecular weight:511.36
Ref: TM-T79326
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[D-Pro2] Spantide I TFA
[D-Pro2] Spantide I TFA is an analog of Spantide I, a selective antagonist of the NK1 receptor [1].
Formula:C₇₅H₁₀₈N₂₀O₁₃·xC₂HF₃O₂
Purity:98%
Color and Shape:Solid
Ref: TM-T80031
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Tetrapeptide-1
CAS:
- 1632354-04-1
Tetrapeptide-1 is a bioactive peptide renowned for its antioxidant properties and has been cited as an ingredient in cosmetics [1].
Formula:C₂₀H₃₆N₄O₆
Purity:98%
Color and Shape:Solid
Molecular weight:428.52
Ref: TM-T80202
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Val9-Oxytocin
CAS:
- 1021701-88-1
Val9-Oxytocin, an Oxytocin analog where Gly9 is substituted with Val9 [1], functions as a complete antagonist of the vasopressin (V1a) receptor.
Formula:C₄₆H₇₂N₁₂O₁₂S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1049.27
Ref: TM-T80136
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Ala5-Galanin (2-11)
CAS:
- 859843-84-8
Ala5-Galanin (2-11) is a specific agonist for the galanin receptor 2 (GAL2R) with an affinity constant (Ki) of 258 nM [1].
Formula:C₅₄H₈₁N₁₃O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1120.3
Ref: TM-T80517
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AD186
AD186, a potent and selective S1R agonist, exhibits dissociation constants (Kis) of 2.7 nM for S1R and 27 nM for S2R.
Formula:C₂₂H₂₈N₂
Purity:98%
Color and Shape:Solid
Molecular weight:320.47
Ref: TM-T78915
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Galanin-Like Peptide (porcine)
CAS:
- 245114-96-9
Galanin-Like Peptide (porcine) is a 60 amino acid neuropeptide originally isolated from the porcine hypothalamus.
Formula:C₂₈₁H₄₄₃N₈₁O₇₈
Purity:98%
Color and Shape:Solid
Molecular weight:6204.02
Ref: TM-T80145
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hNTS1R agonist-1
Compound 10, an hNTS1R agonist-1, acts as a full agonist with a strong affinity for hNTS1R (K i: 6.9 nM), showing the ability to cross the blood-brain barrier (
Formula:C₃₇H₆₂N₁₀O₉
Purity:98%
Color and Shape:Solid
Molecular weight:790.95
Ref: TM-T78954
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N,N′-Diferuloylputrescine
CAS:
- 42369-86-8
N,N′-Diferuloylputrescine acts as a pigment inhibitor, showing a 57% reduction in pigmentation.
Formula:C₂₄H₂₈N₂O₆
Purity:98%
Color and Shape:Solid
Molecular weight:440.49
Ref: TM-T79996
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Sigma-1 receptor antagonist 4
Sigma-1 receptor antagonist 4 (Compound 32) is a potent σ1R antagonist that significantly enhances morphine's analgesic effects and reverses morphine-induced
Formula:C₂₂H₂₆N₂O
Color and Shape:Solid
Molecular weight:334.45
Ref: TM-T74813
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Corticotropin-releasing factor (human) acetate
Corticotropin-releasing factor (human) acetate stimulates to synthesize and secret adrenocorticotropin in the anterior pituitary.
Purity:98.30%
Color and Shape:Liquid
Ref: TM-TP1144L
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Nα-Methylhistamine FA
Nα-Methylhistamine FA is a histamine H3 receptor agonist
Formula:C₇H₁₃N₃O₂
Purity:>99.99%
Color and Shape:Solid
Molecular weight:171.2
Ref: TM-T23038L
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Meclinertant
CAS:
- 146362-70-1
Meclinertant: selective NTS1 antagonist, blocks Ca2+ mobilization, with anxiolytic and anti-addictive properties.
Formula:C₃₂H₃₁ClN₄O₅
Purity:97.51% - 99.44%
Color and Shape:Solid
Molecular weight:587.07
Ref: TM-T16034
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Cholecystokinin (26-33) free acid
CAS:
- 103974-46-5
Cholecystokinin (26-33) free acid is part of CCK and induces mild taste aversion conditioning in rats.
Formula:C₄₉H₆₁N₉O₁₄S₂
Purity:99.14%
Color and Shape:Soild
Molecular weight:1064.19
Ref: TM-TP2500
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Adatanserin hydrochloride
CAS:
- 144966-96-1
Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.
Formula:C₂₁H₃₂ClN₅O
Purity:99.64%
Color and Shape:Solid
Molecular weight:405.96
Ref: TM-T29645
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Binospirone
CAS:
- 102908-59-8
Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.
Formula:C₂₀H₂₆N₂O₄
Purity:97.57% - 98.96%
Color and Shape:Soild
Molecular weight:358.43
Ref: TM-T71138L
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Lanepitant 2HCl
CAS:
- 170508-05-1
Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist that can be used to study painful neuropathy-like disorders such as migraine.
Formula:C₃₃H₄₇Cl₂N₅O₃
Purity:98.67%
Color and Shape:Solid
Molecular weight:632.66
Ref: TM-T25616
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Org 13011
CAS:
- 142494-12-0
Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.
Formula:C₁₈H₂₅F₃N₄O
Purity:98.02%
Color and Shape:Soild
Molecular weight:370.41
Ref: TM-T28258L
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VVZ-149
VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.
Color and Shape:Solid
Ref: TM-T35087
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A2A/A3 AR antagonist-1
A2A/A3 AR antagonist-1 is a dual fluorescent AR ligand with K i of 90 nM (hA2A) & 31.8 nM (hA3).
Formula:C₅₆H₇₁N₁₅O₁₂S₂
Color and Shape:Solid
Molecular weight:1210.39
Ref: TM-T74606
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Kisspeptin-54(human) TFA
Endogenous kisspeptin-54(human) TFA targets KISS1/GPR54 receptors; Ki: 1.81 nM (rat), 1.45 nM (human); inhibits metastasis, boosts gonadotropin.
Formula:C₂₅₈H₄₀₁N₇₉O₇₈·C₂HF₃O₂
Color and Shape:Solid
Molecular weight:5971.45
Ref: TM-T75774
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13,14-dihydro Prostaglandin F2α
CAS:
- 27376-74-5
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain.
Formula:C₂₀H₃₆O₅
Color and Shape:Solid
Molecular weight:356.503
Ref: TM-T36146
+ Info
Satavaptan
CAS:
- 185913-78-4
Satavaptan is a vasopressin V2 receptor antagonist. Satavaptan improves the control of ascites in cirrhosis.
Formula:C₃₃H₄₅N₃O₈S
Color and Shape:Solid
Molecular weight:643.79
Ref: TM-T28664
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Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
Biotin-labeled GLP-1-(7-36) amide; a gut peptide that enhances insulin release.
Formula:C₁₆₅H₂₅₂N₄₄O₄₈S
Color and Shape:Solid
Molecular weight:3652.1
Ref: TM-T76330
+ Info
Cyclic SSTR agonist octreotide
Cyclic SSTR agonist octreotide is a Octreotide , serving as the cyclic Somatostatin Receptor SSTR agonist [1] .
Formula:C₅₃H₇₁N₁₁O₁₄S₂
Color and Shape:Solid
Molecular weight:1150.33
Ref: TM-T76544
+ Info
Alosetron-d3
CAS:
- 1190043-13-0
Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.
Formula:C₁₇H₁₈N₄O
Purity:98%
Color and Shape:Solid
Molecular weight:297.37
Ref: TM-T19191
+ Info
Bamosiran
CAS:
- 1337968-84-9
Bamosiran, a small interfering RNA (siRNA), specifically targets the β-adrenergic receptor 2 to reduce intraocular pressure.
Color and Shape:Solid
Ref: TM-T75155
+ Info
L-796,778 acetate
L-796,778 acetate is a slective somatostatin receptor agonist with IC50 of 24nM for sst3, for sst1, sst2, sst4 and sst5, IC50 is >1000nM.
Formula:C₃₁H₄₄N₆O₉
Purity:98%
Color and Shape:Soild
Molecular weight:644.72
Ref: TM-T32511L
+ Info
4-Butyl-α-agarofuran
CAS:
- 272126-07-5
4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.
Formula:C₁₈H₃₀O
Color and Shape:Solid
Molecular weight:262.43
Ref: TM-T75257
+ Info
MK-0493 HCl
CAS:
- 455957-71-8
MK-0493 is a novel, potent, and selective agonist for melanocortin receptor 4 (MC4R).
Formula:C₃₀H₃₉Cl₂F₂N₃O₂
Color and Shape:Solid
Molecular weight:582.55
Ref: TM-T33419
+ Info
15(S)-HpEPE
CAS:
- 125992-60-1
15(S)-HpEPE, a monohydroperoxy fatty acid, forms when 15-lipoxygenase acts on EPA, with expected biological activities akin to 15(S)-HpETE.
Formula:C₂₀H₃₀O₄
Color and Shape:Solid
Molecular weight:334.456
Ref: TM-T37402
+ Info
Acetyl-Amylin (8-37) (human)
CAS:
- 178603-79-7
Acetyl-Amylin (8-37) (human) is a specific amylin antagonist [1] .
Formula:C₁₄₀H₂₁₈N₄₂O₄₆
Color and Shape:Solid
Molecular weight:3225.48
Ref: TM-T76645
+ Info
[Asu1,6-Arg8]Vasopressin
CAS:
- 40944-53-4
[Asu1,6-Arg8]Vasopressin, a vasopressin agonist, boosts cAMP and ACTH release in cultured rat pituitary cells.
Formula:C₄₈H₆₈N₁₄O₁₂
Color and Shape:Solid
Molecular weight:1033.14
Ref: TM-T76510
+ Info
Motilin, canine
CAS:
- 85490-53-5
Motilin canine, a 22-amino acid peptide, functions as a robust gastrointestinal smooth muscle contraction agonist.
Formula:C₁₂₀H₁₉₄N₃₆O₃₄
Purity:98%
Color and Shape:Solid
Molecular weight:2685.05
Ref: TM-TP1098
+ Info
5-OMe-UDP trisodium salt
CAS:
- 1207530-98-0
Potent P2Y6 agonist
Formula:C₁₀H₁₆N₂O₁₃P₂
Purity:98%
Color and Shape:Solid
Molecular weight:434.19
Ref: TM-T22525
+ Info
Tocrifluor T1117
CAS:
- 1186195-59-4
Fluorescent form of AM 251, CB1 receptor antagonist
Formula:C₅₆H₅₃Cl₂N₇O₅
Purity:98%
Color and Shape:Solid
Molecular weight:974.97
Ref: TM-T23464
+ Info
Leukotriene B4 Ethanolamide
CAS:
- 877459-63-7
LTB4 binds to BLT1 (high affinity) and BLT2. LTB4-EA, a metabolite, is a stronger BLT1 antagonist, suggesting anti-inflammatory properties.
Formula:C₂₂H₃₇NO₄
Color and Shape:Solid
Molecular weight:379.541
Ref: TM-T37619
+ Info
Orexin A (human, rat, mouse) (TFA)
Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.
Formula:C₁₅₄H₂₄₄N₄₇F₃O₄₆S₄
Purity:98%
Color and Shape:Solid
Molecular weight:3675.12
Ref: TM-TP1550
+ Info
ACTH (1-17)
CAS:
- 7266-47-9
ACTH (1-17), a potent MC1 receptor agonist with a Ki of 0.21 nM, is a variant of corticotropin from the pituitary gland.
Formula:C₉₅H₁₄₅N₂₉O₂₃S
Purity:98%
Color and Shape:Solid
Molecular weight:2093.41
Ref: TM-TP1011
+ Info
TAK-683 acetate
TAK-683 acetate: potent KISS1R agonist (IC50=170 pM), stable, nonapeptide. Affects GnRH, FSH, LH, testosterone; potential in prostate cancer research.
Formula:C₆₆H₈₇N₁₇O₁₅
Color and Shape:Solid
Molecular weight:1358.5
Ref: TM-T76048
+ Info
VU0453379 hydrochloride
VU0453379 hydrochloride: selective CNS-penetrant GLP-1R PAM, EC50 1.3 μM.
Formula:C₂₆H₃₅ClN₄O₂
Color and Shape:Solid
Molecular weight:471.03
Ref: TM-T73840
+ Info
L-770644
CAS:
- 173901-95-6
L-770644 is an agonist of B3 adrenergic receptor.
Formula:C₃₀H₃₇N₇O₄S
Color and Shape:Solid
Molecular weight:591.72
Ref: TM-T24377
+ Info
N6-Benzyl-5'-ethylcarboxamido adenosine
CAS:
- 152918-32-6
N6-Benzyl-5'-ethylcarboxamido adenosine is a selective A3 adenosine receptor agonist.
Formula:C₁₉H₂₂N₆O₄
Color and Shape:Solid
Molecular weight:398.42
Ref: TM-T39011
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Urocortin II, human TFA
hUcn II, a CRF family member, targets CRF2 receptor, has time-linked stress regulation effects, showing mild motor suppression and delayed anxiolytic action.
Formula:C₁₉₆H₃₄₀F₃N₆₃O₅₆S
Purity:98%
Color and Shape:Solid
Molecular weight:4564.3
Ref: TM-TP1557
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β-CGRP, human
CAS:
- 101462-82-2
β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular
Formula:C₁₆₂H₂₆₇N₅₁O₄₈S₃
Purity:98%
Color and Shape:Solid
Molecular weight:3793.41
Ref: TM-TP1130
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Pasireotide (diaspartate)
CAS:
- 1421446-02-7
Pasireotide diaspartate (SOM230) has high agonist activity at sst1/2/3/5, less at sst4; it's antiproliferative and proapoptotic.
Formula:C₆₆H₈₀N₁₂O₁₇
Color and Shape:Solid
Molecular weight:1313.41
Ref: TM-T75248
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Maridebart
CAS:
- 2761478-99-1
Maridebart is a humanized IgG1-kappa monoclonal antibody that targets the GIPR (gastric inhibitory polypeptide receptor) [1].
Color and Shape:Liquid
Ref: TM-T81862
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Baloncibart
CAS:
- 2988795-75-9
Baloncibart is a human IgG4K monoclonal antibody that targets NPR1.
Color and Shape:Liquid
Ref: TM-T9901A-888
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D[LEU4,LYS8]-VP TFA
D[LEU4,LYS8]-VP TFA: V1b receptor agonist; K_i: 0.16 nM (rat), 0.52 nM (human), 1.38 nM (mouse); weak antidiuretic/vasopressor/oxytocic.
Formula:C₄₉H₆₈F₃N₁₁O₁₃S₂
Color and Shape:Solid
Molecular weight:1140.25
Ref: TM-T75826
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Hemopressin(rat)
CAS:
- 568588-77-2
Peptide inhibitor for ep24.15, neurolysin & ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain & food intake.
Formula:C₅₃H₇₇N₁₃O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:1088.27
Ref: TM-TP1901
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d[Cha4]-AVP
CAS:
- 500170-27-4
Potent human V1B vasopressin receptor agonist; Ki: V1B=1.2 nM; increases ACTH, corticosterone; low vasopressor effect.
Formula:C₅₀H₇₁N₁₃O₁₁S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1094.31
Ref: TM-TP2082
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Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.
Formula:C₁₉H₃₈ClN₅O₂S
Color and Shape:Solid
Molecular weight:436.06
Ref: TM-T75003
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MMC(TMZ)-TOC TFA
MMC(TMZ)-TOC TFA exhibits high binding affinity and selectivity for the somatostatin receptor subtype 2 (SSTR2). It targets the delivery of TMZ to SSTR2-positive tumor cells, making MMC(TMZ)-TOC TFA useful for cancer research.
Formula:C₇₄H₉₉F₃N₂₀O₂₁S₂
Color and Shape:Solid
Molecular weight:1725.82
Ref: TM-T204151
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MrgprX2 antagonist-5
CAS:
- 2527815-74-1
MrgprX2 antagonist-5 from patent WO2020223255A1 inhibits MrgprX2, useful for inflammatory skin disorder studies.
Formula:C₁₉H₁₃ClF₂N₄O₂S
Color and Shape:Solid
Molecular weight:434.85
Ref: TM-T40176
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Antisauvagine-30 TFA
aSvg-30 TFA: potent CRF2 receptor antagonist, Kd 1.4 nM (mCRFR2β), 150 nM (CRFR1).
Formula:C₁₆₃H₂₇₅N₄₈F₃O₄₉S
Color and Shape:Solid
Molecular weight:3764.28
Ref: TM-T75805
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Cetirizine Impurity C dihydrochloride
CAS:
- 2702511-37-1
Cetirizine Impurity C dihydrochloride is a Cetirizine metabolite and long-acting H1-antihistamine.
Formula:C₂₁H₂₇Cl₃N₂O₃
Color and Shape:Solid
Molecular weight:461.81
Ref: TM-T73962
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YM 09538
CAS:
- 70958-86-0
YM 09538 is a biochemical.
Formula:C₁₈H₂₅ClN₂O₅S
Color and Shape:Solid
Molecular weight:416.92
Ref: TM-T35252
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Detomidine carboxylic acid
CAS:
- 115664-39-6
Detomidine carboxylic acid, a urine metabolite of detomidine, is a synthetic α2-agonist, animal analgesic, with cardiac, respiratory, and diuretic effects.
Formula:C₁₂H₁₂N₂O₂
Purity:98%
Color and Shape:Solid
Molecular weight:216.24
Ref: TM-T11010
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GLP-1R agonist 15
CAS:
- 2763621-11-8
GLP-1R agonist 15 (Compound 101) is a GLP-1 receptor agonist [1] .
Formula:C₄₆H₄₇FN₈O₇S
Color and Shape:Solid
Molecular weight:874.98
Ref: TM-T74609
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Lys-[Des-Arg9]Bradykinin
CAS:
- 71800-36-7
Selective bradykinin B1 agonist with Ki 0.12 nM; inactive at B2 (>30,000 nM). Lowers blood pressure, more potent than Des-Arg9-Bradykinin.
Formula:C₅₀H₇₃N₁₃O₁₁
Purity:98%
Color and Shape:Solid
Molecular weight:1032.21
Ref: TM-TP1918
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Scyliorhinin II
CAS:
- 112748-19-3
Scyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.
Formula:C₇₇H₁₁₉N₂₁O₂₆S₃
Purity:98%
Color and Shape:Solid
Molecular weight:1851.09
Ref: TM-TP1851
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GLP-1R agonist 29
GLP-1R agonist 29 (Compound 20) is a GLP-1R agonist that induces hGLP-1R-mediated cAMP stimulation with an EC50 of 0.018 nM. It exhibits favorable pharmacokinetic properties and shows good in vivo exposure, with an AUC0-∞,sc of 77688 ng·h/mL.
Color and Shape:Odour Solid
Ref: TM-T206400
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PACAP-Related Peptide (PRP), human
PRP, human: 29-amino-acid PACAP precursor segment, synthesized for biological/structural research.
Formula:C₁₃₉H₂₂₉N₄₁O₄₂
Purity:98%
Color and Shape:Solid
Molecular weight:3146.57
Ref: TM-TP1850
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Cetirizine Impurity C
CAS:
- 83881-59-8
Cetirizine Impurity C - a metabolite of hydroxyzine, is a long-acting, oral H1-antihistamine.
Formula:C₂₁H₂₅ClN₂O₃
Color and Shape:Solid
Molecular weight:388.89
Ref: TM-T36945
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Brexpiprazole S-oxide D8
CAS:
- 2748605-29-8
Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.
Formula:C₂₅H₁₉D₈N₃O₃S
Purity:98%
Color and Shape:Solid
Molecular weight:457.61
Ref: TM-T10611
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Vortioxetine D8
CAS:
- 2140316-62-5
Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).
Formula:C₁₈H₂₂N₂S
Purity:98%
Color and Shape:Solid
Molecular weight:306.5
Ref: TM-T13308
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BAY-6672 hydrochloride
CAS:
- 2247520-31-4
BAY-6672 hydrochloride is a potent, selective antagonist of the human Prostaglandin F (FP) receptor, exhibiting an IC50 value of 11 nM.
Formula:C₂₆H₂₈BrCl₂N₃O₃
Color and Shape:Solid
Molecular weight:581.33
Ref: TM-T74213
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NF 340
CAS:
- 202982-98-7
P2Y11 antagonist
Formula:C₃₇H₃₀N₄Na₄O₁₅S₄
Purity:98%
Color and Shape:Solid
Molecular weight:990.87
Ref: TM-T23064
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[D-Phe12]-Bombesin
CAS:
- 108437-87-2
Bombesin receptor antagonist
Formula:C₇₄H₁₁₂N₂₂O₁₈S
Purity:98%
Color and Shape:Solid
Molecular weight:1629.88
Ref: TM-TP2239
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Pancreatic Polypeptide, rat
CAS:
- 90419-12-8
Rat Pancreatic Polypeptide: 36-amino acid peptide, NPYR4 agonist, secreted by islet PP cells.
Formula:C₁₉₅H₂₉₈N₅₈O₅₇S
Purity:98%
Color and Shape:Solid
Molecular weight:4398.87
Ref: TM-TP1044
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Bremelanotide
CAS:
- 189691-06-3
Bremelanotide is a synthetic peptide analog of alpha-MSH and is an agonist at melanocortin receptors including the MC3R and MC4R.
Formula:C₅₀H₆₈N₁₄O₁₀
Purity:98%
Color and Shape:White Powder
Molecular weight:1025.16
Ref: TM-T20467