GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5696 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

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Urocortin, rat
CAS:
- 171543-83-2
Endogenous CRF agonist. Ki values are 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β respectively.
Formula:C₂₀₆H₃₃₈N₆₂O₆₄
Purity:98%
Color and Shape:Solid
Molecular weight:4707.26
Ref: TM-TP1020
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Parstatin(mouse)
CAS:
- 1065756-01-5
Peptide inhibits endothelial migration/proliferation (IC50 ~20μM), induces cell cycle arrest, triggers apoptosis, and has cardioprotective effects.
Formula:C₁₈₉H₃₂₆N₅₈O₅₇S₃
Purity:98%
Color and Shape:Solid
Molecular weight:4419.19
Ref: TM-TP1966
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CCR6 inhibitor 1
CAS:
- 2437547-04-9
CCR6 inhibitor 1 selectively blocks CCR6 (0.45 nM in monkeys, 6 nM in humans), aiding in vitro/vivo disease studies.
Formula:C₂₄H₂₃F₃N₄O₃S
Purity:99.89%
Color and Shape:Solid
Molecular weight:504.52
Ref: TM-T10715
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Adrenomedullin (AM) (22-52), human TFA
Adrenomedullin (AM) human (22-52) is a truncated NH2 TFA-modified adrenal medullary receptor antagonist.
Formula:C₁₆₁H₂₅₃N₄₆F₃O₅₀
Purity:98%
Color and Shape:Solid
Molecular weight:3690.06
Ref: TM-TP1256
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AG 045572
CAS:
- 263847-55-8
AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 is
Formula:C₃₀H₃₇NO₅
Purity:99.96%
Color and Shape:Solid
Molecular weight:491.62
Ref: TM-T22025
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CCR8 agonist 1
CCR8 agonist1 (Compound 2) is an activator of CCR8 and is applicable in studies related to autoimmune diseases.
Formula:C₂₂H₂₉NO₃
Color and Shape:Solid
Molecular weight:355.47
Ref: TM-T203220
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U 67827E
CAS:
- 103494-23-1
U 67827E is a long-lasting cholecystokinin agonist. It acts by decreases food intake.
Formula:C₅₃H₆₈N₁₀O₁₇S
Purity:98%
Color and Shape:Solid
Molecular weight:1149.24
Ref: TM-T26305
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Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin
CAS:
- 136105-89-0
Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), acts as a weak agonist at the antidiuretic receptor but is a potent
Formula:C₄₅H₆₃N₁₅O₁₁S₂
Color and Shape:Solid
Molecular weight:1054.21
Ref: TM-T76509
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Adrenomedullin (AM) (22-52), human acetate
Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and an
Formula:C₁₆₁H₂₅₆N₄₆O₅₀
Purity:99.42%
Color and Shape:Solid
Molecular weight:3636.09
Ref: TM-TP1257L
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CCG258208 hydrochloride
GRKs-IN-1 HCl (14as) strongly inhibits GRK2 (IC50=130nM) & GRK5 (IC50=7.1μM), is a paroxetine derivative with 100x cardiac boost.
Color and Shape:Solid
Ref: TM-T35875
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ACTH (1-14)
CAS:
- 25696-21-3
ACTH (1-14) is a pituitary hormone fragment that controls cortisol and androgen levels.
Formula:C₇₇H₁₀₉N₂₁O₂₀S
Purity:98%
Color and Shape:Solid
Molecular weight:1680.88
Ref: TM-TP1238
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(Hyp³)-Bradykinin acetate
(Hyp³)-Bradykinin acetate is an agonist of bradykinin B2 receptor and stimulates inositol phosphate production in cultured human fibroblasts.
Formula:C₅₂H₇₇N₁₅O₁₄
Purity:99.46%
Color and Shape:Solid
Molecular weight:1136.26
Ref: TM-T36442L
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4-P-PDOT
CAS:
- 134865-74-0
4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
Formula:C₁₉H₂₁NO
Purity:99.91%
Color and Shape:Solid
Molecular weight:279.38
Ref: TM-T14042
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NPC 567 acetate
NPC 567 acetate is a bradykinin B2 antagonist and can be used in studies about the treatment of allergic airway disease.
Formula:C₆₂H₉₁N₁₉O₁₅
Purity:97.72%
Color and Shape:Solid
Molecular weight:1342.5
Ref: TM-T21060L
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Carazolol-d7
CAS:
- 1173021-02-7
Carazolol-d7 is the deuterium-labeled isotope of Carazolol, commonly used in pharmacokinetic studies to investigate the metabolic pathways of Carazolol.
Formula:C₁₈H₂₂N₂O₂
Color and Shape:Solid
Molecular weight:305.42
Ref: TM-T203713
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PG 931 acetate
PG 931 acetate is a potent agonist of melanocortin 4 (MC4) receptors.
Formula:C₆₁H₈₉N₁₅O₁₃
Purity:98.74%
Color and Shape:Solid
Molecular weight:1240.45
Ref: TM-TP1953L
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MD01-67
CAS:
- 2468971-42-6
MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain.
Formula:C₃₇H₅₈N₈O₈
Color and Shape:Solid
Molecular weight:742.91
Ref: TM-TP2936
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PAR 4 (1-6) (TFA)
PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide derived from protease-activated receptor 4 (PAR 4), serves as a specific agonist for PAR 4.
Formula:C₂₈H₄₁N₇O₉·xC₂HF₃O₂
Color and Shape:Solid
Ref: TM-T75904
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15(R)-17-phenyl trinor Prostaglandin F2α
CAS:
- 41639-71-8
17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular
Formula:C₂₃H₃₂O₅
Color and Shape:Solid
Molecular weight:388.5
Ref: TM-T37930
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Protease-Activated Receptor-1, PAR-1 Agonist
CAS:
- 141136-85-8
Selective peptide agonist that mimics thrombin to activate PAR-1 receptor, enabling targeted receptor activation.
Formula:C₃₅H₅₈N₁₀O₉
Color and Shape:Solid
Molecular weight:762.91
Ref: TM-T38836