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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5378 products of "GPCR/G-Protein"

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  • Lys-(Des-Arg9,Leu8)-Bradykinin

    CAS:
    <p>Lys-(Des-Arg9,Leu8)-Bradykinin is a selective antagonist of the bradykinin B1 receptor [1].</p>
    Formula:C47H75N13O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:998.18
  • Spns2-IN-1


    <p>Spns2-IN-1 is a potent Spns2 inhibitor, effectively impeding Spns2-dependent S1P transport with an IC50 value of 1.4±0.3 μM, crucial for modulating the immune</p>
    Purity:98%
    Color and Shape:Odour Solid
  • [Deamino-Pen1,Val4,D-Arg8]-vasopressin

    CAS:
    <p>[Deamino-Pen1,Val4,D-Arg8]-vasopressin (AVP-A) is an antagonist of arginine-vasopressin (AVP).</p>
    Formula:C48H69N13O11S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1068.27
  • Prolactin Releasing Peptide (1-31), human

    CAS:
    <p>Human Prolactin Releasing Peptide (1-31) is a potent GPR10 agonist; Ki values are 1.03 nM (human) and 0.33 nM (rat).</p>
    Formula:C160H252N56O42S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3664.15
  • (D-Arg8)-Inotocin

    CAS:
    <p>'(D-Arg8)-Inotocin is a potent, selective, and competitive antagonist of the vasopressin receptor (V 1a R), exhibiting a binding affinity (K i) of 1.3 nM.</p>
    Formula:C39H68N14O11S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:973.17
  • Tafluprost acid

    CAS:
    <p>Tafluprost acid is a selective agonist at the prostaglandin F receptor.</p>
    Formula:C22H28F2O5
    Color and Shape:Solid
    Molecular weight:410.46
  • Heterobivalent ligand-1


    <p>Heterobivalent ligand-1 targets A2A-D2 receptor heteromer with affinity: Kd for A2A=2.1 nM, D2=0.13 nM.</p>
    Formula:C86H115FN16O21
    Color and Shape:Solid
    Molecular weight:1727.93
  • S1R agonist 2

    CAS:
    <p>S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.</p>
    Formula:C21H27NO
    Purity:98.85%
    Color and Shape:Solid
    Molecular weight:309.45
  • Adrenomedullin (16-31), human

    CAS:
    <p>Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM).</p>
    Formula:C82H129N25O21S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1865.19
  • Chir 2279

    CAS:
    <p>CHIR 2279, a peptoid trimer, binds alpha 1-adrenoceptors, blocking epinephrine effects in dogs (pseudo pA2 6.86).</p>
    Formula:C34H36N4O4
    Color and Shape:Solid
    Molecular weight:564.67
  • Eloralintide

    CAS:
    <p>Eloralintide (LY 3841136) is an AMYR agonist, anticipated for research in type 2 diabetes and obesity.</p>
    Formula:C201H319N49O65S2
    Color and Shape:Solid
    Molecular weight:4526.1
  • BAY-6672 hydrochloride

    CAS:
    BAY-6672 hydrochloride is a potent, selective antagonist of the human Prostaglandin F (FP) receptor, exhibiting an IC50 value of 11 nM.
    Formula:C26H28BrCl2N3O3
    Color and Shape:Solid
    Molecular weight:581.33
  • 17-TFM-PGF1α

    CAS:
    <p>17-TFM-PGF1α (Compound 8) is a saturated prostaglandin analog. It exhibits a high affinity and receptor selectivity for the human prostaglandin F receptor (hFP receptor), with an EC50 of 85 nM.</p>
    Formula:C24H35F3O5
    Color and Shape:Solid
    Molecular weight:460.53
  • 8β-Hydroxy-exo-THC

    CAS:
    <p>8β-Hydroxy-exo-THC, a cannabinoid ether analog, exhibits weak affinity for receptor sites with an IC50 of 1.2 μM.</p>
    Formula:C21H30O3
    Color and Shape:Solid
    Molecular weight:330.46
  • 2,6-DMA hydrochloride

    CAS:
    <p>2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.</p>
    Formula:C11H18ClNO2
    Color and Shape:Solid
    Molecular weight:231.72
  • Methylhexanamine hydrochloride

    CAS:
    <p>Methylhexanamine hydrochloride is a fatty amine and vasoconstrictor that functions as a nasal decongestant when inhaled through the nasal mucosa.</p>
    Formula:C7H18ClN
    Color and Shape:Solid
    Molecular weight:151.68
  • 8-Chloro caffeine

    CAS:
    <p>8-Chloro caffeine binds to adenosine receptors with a Ki of 30 µM. It enhances UV-induced chromosomal aberrations in the Cl-I type Chinese hamster embryo lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine.</p>
    Formula:C8H9ClN4O2
    Color and Shape:Solid
    Molecular weight:228.64
  • UKH-1114

    CAS:
    <p>UKH-1114 is a potent σ2 receptor/Tmem97 agonist with a Ki value of 46 nM, demonstrating antinociceptive effects against mechanical hypersensitivity. This compound alleviates mechanical hypersensitivity in mice caused by nerve injury without inducing motor impairment and is a promising candidate for neuropathic pain research.</p>
    Formula:C22H24F3NO
    Color and Shape:Solid
    Molecular weight:375.43
  • sGC activator 2


    <p>sGC activator 2 (Compound 16a) acts as an activator of soluble guanylate cyclase (sGC), enhancing the production of cGMP and exhibiting vasoprotective and anti-inflammatory properties.</p>
    Formula:C21H21FN8O3
    Color and Shape:Solid
    Molecular weight:452.44
  • QWF acetate


    <p>QWF acetate is a Substance P antagonist peptide that specifically inhibits the binding to its receptor, NK1, and inhibits the activation of MRGPRX2.</p>
    Formula:C40H47N5O10
    Purity:96.65%
    Color and Shape:Solid
    Molecular weight:757.84