
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,022 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5983 products of "GPCR/G-Protein"
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5α-Pregnane-3α,20α-diol
CAS:5α-Pregnane-3α,20α-diol, an active metabolite of progesterone, is synthesized through intermediates 5α-pregnane-20α-ol-3-one and 5α-pregnane-3α-ol-20-one fromFormula:C21H36O2Color and Shape:SolidMolecular weight:320.51PZ-1190
CAS:PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].Formula:C27H30N4O2S2Purity:98%Color and Shape:SolidMolecular weight:506.68Desethoxy Quetiapine hydrochloride
CAS:Desethoxy quetiapine, an active metabolite of the atypical antipsychotic quetiapine, primarily forms through the action of the cytochrome P450 (CYP) isoform CYP3A5. This compound binds to dopamine D2 receptors with an IC50 value of 1,330 nM. In vivo, desethoxy quetiapine at dosages of 20 and 40 mg/kg mitigates dopamine receptor agonist apomorphine-induced climbing behavior and ameliorates swimming deficits in mice, showcasing its potential modulatory effects on dopamine-mediated behaviors.Formula:C19H21N3OSHClColor and Shape:SolidMolecular weight:412.38Maropitant citrate anhydrous
CAS:Maropitant citrate anhydrous is a neurokinin (NK1) receptor antagonist.Formula:C38H48N2O8Color and Shape:SolidMolecular weight:660.8SB 649915
CAS:SB 649915 is a serotonin reuptake inhibitor and 5-HT1A and 5-HT1B receptor antagonist.Formula:C26H29N3O3Color and Shape:SolidMolecular weight:431.535-HT2 agonist-1
CAS:Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.Formula:C19H23ClN2O2Purity:98%Color and Shape:SolidMolecular weight:346.85AR-08
CAS:AR-08 is a potent α2-adrenergic receptor agonist for the study of ADHD and attention deficit.Formula:C12H12N6Purity:99.7%Color and Shape:SolidMolecular weight:240.26PD 160170
CAS:neuropeptide Y1 receptor antagonistFormula:C18H17N3O4SPurity:98%Color and Shape:SolidMolecular weight:371.41L 659837
CAS:L 659837 is an antagonist of ANC-2, lactam, and tackykinin.Formula:C40H52N8O7SColor and Shape:SolidMolecular weight:788.96IIIM-8
CAS:IIIM-8 is a melanogenesis inhibitor that suppresses pigment production in both in vitro and in vivo settings, exhibiting no cytotoxic effects on Human AdultFormula:C14H17NO4Purity:98%Color and Shape:SolidMolecular weight:263.29Capeserod HCl
CAS:Capeserod HCl, a 5-hydroxytriptamine 4 (5-HT4) receptor agonist, is used potentially for the treatment of Alzheimer's disease.Formula:C23H26Cl2N4O4Purity:98%Color and Shape:SolidMolecular weight:493.38LBT 999
CAS:LBT 999 is used as a dopamine reuptake inhibitor.Formula:C20H26FNO2Color and Shape:SolidMolecular weight:331.42LY 53857
CAS:LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.Formula:C27H36N2O7Color and Shape:SolidMolecular weight:500.592PAC1R antagonist 1
CAS:PAC1R antagonist 1 is a PAC1 receptor antagonist that inhibits the activation of peptides by pituitary adenylate cyclase and can be used to study tumours.Formula:C17H17ClN6O2Purity:98.43% - 99.56%Color and Shape:SolidMolecular weight:372.81Ref: TM-T78105
1mg87.00€5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire1mL*10mM (DMSO)To inquireApelin agonist 1
CAS:Apelin agonist 1 is an orally available APJ receptor agonist with an EC50 value of 3.2 nM. Apelin agonist 1 is used in the study of cardiovascular disease.Formula:C23H20FN5O5SPurity:97.69% - 99.07%Color and Shape:SolidMolecular weight:497.5Brilaroxazine
CAS:Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.Formula:C22H25Cl2N3O3Purity:99.36%Color and Shape:SolidMolecular weight:450.36Ref: TM-T14782
1mg100.00€5mg236.00€10mg385.00€25mg663.00€50mg954.00€100mg1,305.00€200mg1,738.00€1mL*10mM (DMSO)268.00€TG6-129
CAS:TG6-129 is an EP2 receptor antagonist, blocking PGE2 effects, reducing inflammatory markers with 1.6 µM IC50.Formula:C20H18FN5O3S3Purity:99.55%Color and Shape:SolidMolecular weight:491.58Ref: TM-T28958
1mg114.00€5mg227.00€10mg404.00€25mg665.00€50mg888.00€100mg1,251.00€500mg2,538.00€1mL*10mM (DMSO)321.00€CCG-63802
CAS:CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.Formula:C26H18N4O2SPurity:90%Color and Shape:SolidMolecular weight:450.51BMY-42393
CAS:BMY-42393 is an oral prostacyclin agonist and platelet aggregation inhibitor with IC50 of 0.3-2μM and stimulates adenylate cyclase (EC50 = 25nM).Formula:C25H21NO4Color and Shape:SolidMolecular weight:399.44CB1 antagonist 1
CAS:CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, andFormula:C26H22Cl2N4Purity:98%Color and Shape:SolidMolecular weight:461.39
