GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,023 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5990 products of "GPCR/G-Protein"
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JNJ-37822681 dihydrochloride
CAS:JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。Formula:C17H19Cl2F5N4Purity:99.78%Color and Shape:SolidMolecular weight:445.26Befiradol
CAS:Befiradol (NLX-112) is an agonist of 5-HT1A receptor.Formula:C20H22ClF2N3OColor and Shape:SolidMolecular weight:393.86Minocromil
CAS:Minocromil is a new agent of Anti-asthmatic.Formula:C18H16N2O6Purity:98%Color and Shape:SolidMolecular weight:356.33LY108742
CAS:LY108742 is an antagonist of 5-HT2.Formula:C21H28N2O3Purity:98%Color and Shape:SolidMolecular weight:356.46Quinotolast sodium
CAS:Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.Formula:C17H12N6NaO3Purity:98%Color and Shape:SolidMolecular weight:371.312MNI-444
CAS:MNI-444 is a PET radiotracer for adenosine 2A receptors.Formula:C24H26FN9O2Color and Shape:SolidMolecular weight:491.52RO5527239
CAS:RO5527239 is a potent, orally available GPBAR1 agonist agent.Formula:C28H31N3O3Purity:98%Color and Shape:SolidMolecular weight:457.56GLP-1R agonist 12
CAS:GLP-1R agonist 12 (Compound 123) 是一种 GLP-1R 激动剂，能够用于研究糖尿病。Formula:C34H36N6O4Color and Shape:SolidMolecular weight:592.69SRX246
CAS:SRX246: potent CNS-penetrant V1a antagonist (Ki=0.3 nM), inactive at V1b/V2, negligible binding at 64 other receptor classes.Formula:C42H49N5O5Purity:98%Color and Shape:SolidMolecular weight:703.87β3-AR agonist 2
CAS:β3-AR agonist 2 is a potent and selective agonist of β3-adrenergic receptor (β3-AR with an EC50 of 8 nM).Formula:C27H38N4O7SPurity:98%Color and Shape:SolidMolecular weight:562.68ABT-670
CAS:ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively.Formula:C19H23N3O2Purity:98%Color and Shape:SolidMolecular weight:325.4PF-184563
CAS:PF-184563 is an effective and selective non-peptide antagonist of the V1a receptor with oral activity, suitable for studying Raynaud's disease dysmenorrhoea.Formula:C21H23ClN6Purity:99.67%Color and Shape:SolidMolecular weight:394.917-Phenyl-18,19,20-trinor-PGD2
CAS:17-Phenyl-18,19,20-trinor-PGD2 (17-Phenyl-PGD2), an analogue of prostaglandin D2 (PGD2), acts as a potent inhibitor of platelet aggregation induced by adenosine diphosphate (ADP), exhibiting an IC50 value of 8.4 μM, compared to PGD2's IC50 of 18.6 nM. Additionally, it serves as a weak agonist for cyclic AMP accumulation [1].Formula:C23H30O5Color and Shape:SolidMolecular weight:386.48Prostaglandin F2α serinol amide
CAS:Prostaglandin F2α serinol amide, a serinolamide G protein-coupled receptor, elevates calcium levels in human non-small cell lung cancer cells. Additionally, Prostaglandin F2α functions as a luteinizing hormone in sheep and potentially serves as a nociceptive mediator in the spinal cord [1] [2] [3].Formula:C23H41NO6Color and Shape:SolidMolecular weight:427.582GPR3 agonist-2
CAS:GPR3 agonist-2 (compound 32) is a potent full agonist of the G protein-coupled receptor 3 (GPR3), exhibiting an IC50 value of 260 nM [1].Formula:C14H7F6IO4SColor and Shape:SolidMolecular weight:512.16LY3154885
CAS:LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).Formula:C23H23Cl2N3O2Color and Shape:SolidMolecular weight:444.35CV1808
CAS:CV-1808 is a coronary vasodilator, antihypertensive, and antipsychotic following systemic administration in vivo. CV-1808 is an adenosine A2 receptor agonist.Formula:C16H18N6O4Color and Shape:Off-White To Pale Yellow SolidMolecular weight:358.35Leukotriene B4-3-aminopropylamide
CAS:Leukotriene B4 (LTB4)-3-aminopropylamide is an analog of LTB4 that exhibits potent and selective binding to the BLT1 receptor with Ki values of 5.1 nM at BLT1 and 1,227 nM at BLT2, indicating its high affinity for BLT1 over BLT2. This compound's effects are mediated through interactions with two receptors, BLT1 and BLT2.Formula:C23H40N2O3Color and Shape:SolidMolecular weight:392.6Ono-RS 347
CAS:Ono-RS 347 is a leukotriene antagonists with the activity of SRS-A antagonist.Formula:C26H25N5O4Purity:98%Color and Shape:SolidMolecular weight:471.51SC 34301
CAS:SC 34301 (Enisoprost), a strong oral PGE1 analog, decreases bacterial translocation and increases burned mice survival.Formula:C22H36O5Color and Shape:SolidMolecular weight:380.52
