GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,027 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
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L 743310
CAS:L 743310 is an antagonist of the neurokinin-1 receptor.Formula:C30H33BrF6N4O2Purity:98%Color and Shape:SolidMolecular weight:675.5Maropitant citrate anhydrous
CAS:Maropitant citrate anhydrous is a neurokinin (NK1) receptor antagonist.Formula:C38H48N2O8Color and Shape:SolidMolecular weight:660.8Obestatin(rat) TFA
CAS:Obestatin(rat) TFA, a 23-amino-acid peptide, modulates appetite, gut motility, and body weight; binds GPR39; has anti-inflammatory and antioxidant effects.
Formula:C116H175F3N34O33Color and Shape:SolidMolecular weight:2630.83LY-426965
CAS:LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.Formula:C28H38N2O2Color and Shape:SolidMolecular weight:434.61Glycolithocholic acid 3-sulfate disodium
CAS:Glycolithocholic acid 3-sulfate (disodium) demonstrates inhibitory effects on in vitro HIV-1 replication and has potential applications in HIV infection andFormula:C26H41NNa2O7SColor and Shape:SolidMolecular weight:557.65YM348
CAS:YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).Formula:C14H17N3OPurity:98%Color and Shape:SolidMolecular weight:243.3GR 125487 sulfamate
CAS:GR 125487 sulfamate is a 5-HT4 receptor antagonist.Formula:C19H29FN4O8S2Purity:98%Color and Shape:SolidMolecular weight:524.58AC-099 hydrochloride
CAS:AC-099 hydrochloride is a full agonist of neuropeptide FF2 receptor NPFF2R and a partial agonist of neuropeptide FF1 receptor NPFF1R.Formula:C9H9Cl2F3N4Purity:99.86%Color and Shape:SolidMolecular weight:301.1Butriptyline
CAS:Butriptyline (Butriptylene), a tricyclic antidepressant, is effective when administered orally [1].Formula:C21H27NColor and Shape:SolidMolecular weight:293.45Sucrose octasulfate sodium
CAS:Sucrose octasulfate, a constituent of sulfoaluminum, promotes the release of somatostatin-like immunoreactivity (SLI) through direct interaction with D cellsFormula:C12H14Na8O35S8Color and Shape:SolidMolecular weight:1158.66Ciprostene (calcium salt)
CAS:Ciprostene, a PGI2 stable analog, is less potent, induces hypotension, tachycardia, and inhibits platelet aggregation in monkeys.Formula:C44H74CaO8Color and Shape:SolidMolecular weight:771.146NBI 35965 methanesulfonate
CAS:NBI 35965 hydrochloride is a CRF1 antagonist.Formula:C22H26Cl2N4O3SPurity:98%Color and Shape:SolidMolecular weight:497.44A-349821
CAS:A-349821 is an H3 receptor agonist radioligand.Formula:C28H35F3N2O5Color and Shape:SolidMolecular weight:536.59BMS-194449
CAS:BMS-194449 is a full beta 3 agonist.Formula:C24H24F4N2O6SColor and Shape:SolidMolecular weight:544.52CP-96021 hydrochloride
CAS:CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor receptor (Kis: 34 nM and 37 nM).Formula:C29H22ClFN4OSPurity:98%Color and Shape:SolidMolecular weight:529.03YM-543 choline
CAS:YM-543/ASP-543: Potent, selective SGLT2 inhibitor, reduces blood sugar and improves glucose tolerance in diabetic mice.Formula:C28H37NO7Color and Shape:SolidMolecular weight:499.6O-2545 hydrochloride
CAS:O-2545 is a potent water-soluble central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist with Ki values of 1.5 and 0.32 nM, respectively. Typically, cannabinoid agonists are highly lipophilic and require solubilization through surfactant agents or binding to water miscible substances like albumin, Tween 80, or Emulphor for use. When dissolved in saline, O-2545 has shown high efficacy in mouse behavioral models, administered either intravenously or intracerebroventricularly.Formula:C26H36N2O2HClColor and Shape:SolidMolecular weight:445Desethoxy Quetiapine hydrochloride
CAS:Desethoxy quetiapine, an active metabolite of the atypical antipsychotic quetiapine, primarily forms through the action of the cytochrome P450 (CYP) isoform CYP3A5. This compound binds to dopamine D2 receptors with an IC50 value of 1,330 nM. In vivo, desethoxy quetiapine at dosages of 20 and 40 mg/kg mitigates dopamine receptor agonist apomorphine-induced climbing behavior and ameliorates swimming deficits in mice, showcasing its potential modulatory effects on dopamine-mediated behaviors.Formula:C19H21N3OSHClColor and Shape:SolidMolecular weight:412.38EP2 receptor agonist 4
CAS:EP2 receptor agonist 4 selectively activates the EP2 receptor with an efficacy concentration (EC50) of 43 nM [1].Formula:C23H36O5Color and Shape:SolidMolecular weight:392.53SORT-PGRN interaction inhibitor 2
CAS:SORT-PGRN Interaction Inhibitor 2 is a compound that downregulates SORT1 protein expression and enhances extracellular progranulin (PGRN) secretion in variousFormula:C19H31NOColor and Shape:SolidMolecular weight:289.46
