GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,022 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5985 products of "GPCR/G-Protein"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Abediterol
CAS:Abediterol (LAS100977): potent, long-acting beta-2 agonist for asthma and COPD treatment.Formula:C25H30F2N2O4Color and Shape:SolidMolecular weight:460.51L 163255
CAS:L 163255 is a type of growth hormone secretagogue (GHS).Formula:C28H38N4O4SColor and Shape:SolidMolecular weight:526.69Prostaglandin E1 ethanolamide
CAS:Prostaglandin E1 ethanolamide, an analog of Prostaglandin E1 (PGE1), can potentially inhibit the GLI2-induced expression of target genes such as Gli1 and Ptch1, thereby reducing tumor growth [1].Formula:C22H39NO5Color and Shape:SolidMolecular weight:397.55AZD2423
CAS:AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator and it has an IC50 of 1.2 nM forFormula:C20H29ClFN5O2Purity:98%Color and Shape:SolidMolecular weight:425.93Cyanopindolol fumarate
CAS:Cyanopindolol fumarate is a 5-HT receptor antagonist [1].Formula:C16H21N3O2C4H4O4Color and Shape:SolidMolecular weight:345.4E1R
CAS:E1R is a positive sigma-1 receptor (Sig1R PAM) allosteric modulator. It has a cognition-enhancing activity.Formula:C13H16N2O2Color and Shape:SolidMolecular weight:232.2811-deoxy-16,16-dimethyl Prostaglandin E2
CAS:11-Deoxy-16,16-dimethyl Prostaglandin E2 (11-deoxy-16,16-dimethyl PGE2) is a stable synthetic analog of Prostaglandin E2 (PGE2), acting as an agonist for both EP2 and EP3 receptors. It effectively inhibits gastric acid secretion and ulcer formation in rats, with ED50 values of 1 mg/kg and 0.021 mg/kg, respectively. This compound is also 900 times more potent than Prostaglandin F2α (PGF2α) in inducing contraction of human respiratory tract smooth muscle in vitro.Formula:C22H36O4Color and Shape:SolidMolecular weight:364.526MSX-2
CAS:MSX-2 is an A2A adenosine receptor antagonist.Formula:C21H22N4O4Purity:98%Color and Shape:SolidMolecular weight:394.42GR 127935 hydrochloride
CAS:5-HT1B/1D receptor antagonistFormula:C29H32ClN5O3Purity:98%Color and Shape:SolidMolecular weight:534.05CRTH2-IN-1
CAS:CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.Formula:C21H21FN2O4SPurity:98%Color and Shape:SolidMolecular weight:416.47Sonepiprazole
CAS:Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociationFormula:C21H27N3O3SPurity:99.81%Color and Shape:SolidMolecular weight:401.52PF-04634817
CAS:PF-0463481: safe, well-tolerated, dual CCR2/CCR5 antagonist for diabetic nephropathy; similar human/rodent CCR2 potency, less rodent CCR5 effect.Formula:C25H36F3N5O3Purity:98%Color and Shape:SolidMolecular weight:511.58ATL802
CAS:ATL802 is an adenosine A2B Receptor antagonist.Formula:C24H22F3N7O3Purity:98%Color and Shape:SolidMolecular weight:513.47TASP 0277308
CAS:NH2-UAMC1110 TFA is an aminobutoxy derivative of UAMC1110 used in the synthesis of FAPI-QS. UAMC1110 is a fibroblast activating protein (fap) inhibitor.Formula:C23H28Cl2N6O3SColor and Shape:SolidMolecular weight:539.48Firazorexton hydrate
CAS:Firazorexton hydrate (TAK-994) is a brain-penetrant and orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM.Formula:C22H25F3N2O4SH2OColor and Shape:SolidMolecular weight:497.53NAD 299 hydrochloride
CAS:Selective, high affinity 5-HT1A receptor antagonistFormula:C18H24ClFN2O2Purity:98%Color and Shape:SolidMolecular weight:354.85RP-23618
CAS:RP-23618 is a non-peptidic antagonist of RANTES.Formula:C30H35N5O3S2Purity:98%Color and Shape:SolidMolecular weight:577.76Dersalazine sodium
CAS:Dersalazine, potential ulcerative colitis drug, inhibits PAF & TNFα, reduces inflammation and MPO activity in rats.Formula:C35H32N6NaO4Purity:98%Color and Shape:SolidMolecular weight:623.66916-phenoxy tetranor Prostaglandin E2
CAS:16-phenoxy tetranor PGE2, the free acid form of sulprostone, results from the hydrolysis of the methylsulfonamide bond. It is identified as a minor metabolite in human plasma following the parenteral administration of sulprostone.Formula:C22H28O6Color and Shape:SolidMolecular weight:388.46Tafluprost ethyl ester
CAS:Tafluprost, an analog of prostaglandin F2α (PGF2α) that primarily targets the FP receptor, is employed in glaucoma treatment. Tafluprost (free acid) serves as a potent FP receptor agonist with a Ki value of 0.4 nM. Its derivative, tafluprost ethyl ester, potentially offers enhanced lipid solubility relative to its free acid form, possibly leading to superior tissue absorption and reduced effective concentration requirements.Formula:C24H32F2O5Color and Shape:SolidMolecular weight:438.512
