GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,017 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5983 products of "GPCR/G-Protein"
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Robotnikinin
CAS:Robotnikinin is an Shh signaling inhibitor in a concentration-dependent manner. It acts by exhibiting significant repression of Shh-induced Gli1/Gli2.Formula:C25H27ClN2O4Purity:98%Color and Shape:SolidMolecular weight:454.95N-5984
CAS:N-5984, a β3-adrenergic receptor agonist, is used potentially for the treatment of obesity, overactive bladder and type 2 diabetes.
Formula:C20H22ClNO5Purity:98%Color and Shape:SolidMolecular weight:391.854-hydroxy Nebivolol hydrochloride
CAS:4-Hydroxy Nebivolol, a primary metabolite of Nebivolol, results from the enzymatic hydroxylation of Nebivolol by the cytochrome P450 (CYP) isoform CYP2D6.Formula:C22H25F2NO5HClColor and Shape:SolidMolecular weight:457.915(S)-Fluprostenol
CAS:15(S)-Fluprostenol, an isomer of the FP receptor agonist fluprostenol, serves as a potential active metabolite of 15(S)-fluprostenol isopropyl ester. It can function as an agonist at FP receptors, though with lower potency compared to its 15(R) epimer, fluprostenol.Formula:C23H29F3O6Color and Shape:SolidMolecular weight:458.5Prostaglandin E2 serinol amide
CAS:Prostaglandin E2 Serinol Amide acts as a weak inhibitor against the hydrolysis of [3H]2-oleoylglycerol, but it is non-hydrolyzable and cannot produce PGE2. Consequently, it is unable to inhibit leukotriene B4 biosynthesis, superoxide production, migration, and the release of antimicrobial peptides [1].Formula:C23H39NO6Color and Shape:SolidMolecular weight:425.566SKF 81297 hydrobromide
CAS:SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor，exhibits central activity and is widely used to study the neuromodulatory effects.Formula:C16H17BrClNO2Purity:99.52%Color and Shape:SolidMolecular weight:370.67MB-28767
CAS:MB-28767 is an agonist of prostaglandin E2 (PGE2) receptor.Formula:C22H30O5Color and Shape:SolidMolecular weight:374.47AZD2423
CAS:AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator and it has an IC50 of 1.2 nM forFormula:C20H29ClFN5O2Purity:98%Color and Shape:SolidMolecular weight:425.93SCH 206272
CAS:SCH 206272 is a potent, orally active antagonist of tachykinin NK(1), NK(2), and NK(3) receptor.Formula:C33H41Cl4N5O4Color and Shape:SolidMolecular weight:713.52O-Arachidonoyl glycidol
CAS:O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].Formula:C23H36O3Color and Shape:SolidMolecular weight:360.53MK-1421
CAS:MK-1421 is a potent and selective sstr3 antagonist.Formula:C27H24FN9O2Color and Shape:SolidMolecular weight:525.54(-)-Isoproterenol hydrochloride
CAS:(-)-Isoproterenol hydrochloride is used as a β-adrenergic receptor agonist in the treatment of bradycardia and as a bronchodilator.Formula:C11H17NO3·CIHColor and Shape:SolidMolecular weight:247.72TGR5 agonist 3
CAS:Compound 8, a cholic acid derivative, functions as a selective TGR5 agonist and exhibits an EC50 value of 5 μM [1].Formula:C28H48O5Color and Shape:SolidMolecular weight:464.68MIN-117
CAS:MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.Formula:C25H26Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:538.85Glucagon receptor antagonists-3
CAS:Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist.Formula:C22H30FNO2Purity:98%Color and Shape:SolidMolecular weight:359.48KP496
CAS:KP496 is a selective, dual antagonist for Thromboxane A2 receptor and Leukotriene D4 receptor.Formula:C31H34ClN3O7S3Purity:98%Color and Shape:SolidMolecular weight:692.27Amtolmetin guacil
CAS:Amtolmetin guacil (ST-679) 抑制前列腺素合成和环氧合酶。 Amtolmetin guacil 具有与托美汀类似的 NSAID 特性，具有额外的镇痛、解热和胃保护特性。Formula:C24H24N2O5Purity:99.85%Color and Shape:White Needle-Shaped CrystalMolecular weight:420.46BI-167107
CAS:BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR, Kd of 84 pM).Formula:C21H26N2O4Color and Shape:SolidMolecular weight:370.44CV1808
CAS:CV-1808 is a coronary vasodilator, antihypertensive, and antipsychotic following systemic administration in vivo. CV-1808 is an adenosine A2 receptor agonist.Formula:C16H18N6O4Color and Shape:Off-White To Pale Yellow SolidMolecular weight:358.35Robalzotan
CAS:Robalzotan is a selective 5-HT1A receptor antagonist.Formula:C18H23FN2O2Purity:98%Color and Shape:SolidMolecular weight:318.39
