GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,994 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5963 products of "GPCR/G-Protein"
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O-Arachidonoyl glycidol
CAS:O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].Formula:C23H36O3Color and Shape:SolidMolecular weight:360.53YM348
CAS:YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).Formula:C14H17N3OPurity:98%Color and Shape:SolidMolecular weight:243.3BI-167107
CAS:BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR, Kd of 84 pM).Formula:C21H26N2O4Color and Shape:SolidMolecular weight:370.44Ro-24-0238
CAS:Ro-24-0238 blocks PAF, curbing thromboxane creation and inflammation caused by PAF release.Formula:C27H36N2O2Purity:98%Color and Shape:SolidMolecular weight:420.59EP4 receptor antagonist 1
CAS:EP4 antagonist 1: inhibits human/mouse EP4 receptors (IC50: 6.1/16.2 nM), selective over EP1-EP3 (>10 μM). For cancer immunotherapy.Formula:C23H21F3N4O3Purity:99.53%Color and Shape:SolidMolecular weight:458.43SB-649701
CAS:SB-649701 is a potent antagonist of the human CCR8 receptor, exhibiting a pIC50 value of 7.7, and is utilized in asthma research [1].Formula:C27H28N4O3Purity:98%Color and Shape:SolidMolecular weight:456.54Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Formula:C19H29N5O2Purity:99.35% - 99.89%Color and Shape:SolidMolecular weight:359.47(2R,3S)-E1R
CAS:(2R,3S)-E1R, an enantiomer of E1R, is a sigma-1 receptor modulator for treating cognitive disorders.Formula:C13H16N2O2Purity:98%Color and Shape:SolidMolecular weight:232.28Bima SA
CAS:Bimatoprost Serinol Amide (Bima SA), a prostaglandin analog, shows research potential for glaucoma [1].Formula:C26H39NO6Color and Shape:SolidMolecular weight:461.59[D-Ala6]-LH-RH
CAS:[D-Ala6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor agonist [1].Formula:C56H77N17O13Color and Shape:SolidMolecular weight:1196.32Prostaglandin E2 serinol amide
CAS:Prostaglandin E2 Serinol Amide acts as a weak inhibitor against the hydrolysis of [3H]2-oleoylglycerol, but it is non-hydrolyzable and cannot produce PGE2. Consequently, it is unable to inhibit leukotriene B4 biosynthesis, superoxide production, migration, and the release of antimicrobial peptides [1].Formula:C23H39NO6Color and Shape:SolidMolecular weight:425.566CI-949
CAS:CI-949 inhibits LTC4/D4, histamine, TXB2 release (IC50: 0.5, 11.4, 0.1 μM).Formula:C20H20N6O3Purity:98%Color and Shape:SolidMolecular weight:392.41NCGC00229600
CAS:NCGC00229600: Allosteric inverse TSHR agonist; blocks TSH and antibody TSHR activation; for Graves' disease research.Formula:C30H29N3O3Purity:99.31%Color and Shape:SolidMolecular weight:479.57Ref: TM-T12192
1mg64.00€5mg145.00€10mg212.00€25mg373.00€50mg562.00€100mg848.00€200mg1,121.00€1mL*10mM (DMSO)153.00€MB-28767
CAS:MB-28767 is an agonist of prostaglandin E2 (PGE2) receptor.Formula:C22H30O5Color and Shape:SolidMolecular weight:374.47Thromboxane A2
CAS:Thromboxane A2: unstable, leads to thromboxane B2, induces platelet aggregation, causes vasoconstriction.Formula:C20H32O5Color and Shape:SolidMolecular weight:352.47AR-08
CAS:AR-08 is a potent α2-adrenergic receptor agonist for the study of ADHD and attention deficit.Formula:C12H12N6Purity:99.7%Color and Shape:SolidMolecular weight:240.26KFM19
CAS:KFM19 is a potent and selective adenosine receptor (A1-receptor) antagonist (IC50 : 50 nM) for the study of neurological disorders.Formula:C16H22N4O3Purity:98.62%Color and Shape:SolidMolecular weight:318.37Flesinoxan
CAS:Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).Formula:C22H26FN3O4Color and Shape:SolidMolecular weight:415.46PF-184563
CAS:PF-184563 is an effective and selective non-peptide antagonist of the V1a receptor with oral activity, suitable for studying Raynaud's disease dysmenorrhoea.Formula:C21H23ClN6Purity:99.67%Color and Shape:SolidMolecular weight:394.9GR 125487 sulfamate
CAS:GR 125487 sulfamate is a 5-HT4 receptor antagonist.Formula:C19H29FN4O8S2Purity:98%Color and Shape:SolidMolecular weight:524.58
