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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5378 products of "GPCR/G-Protein"

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  • LY 245769
    Targetmol
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    LY 245769

    CAS:
    <p>LY 245769 is an inhibitor of leukotriene E4 (LTE4).</p>
    Formula:C25H33F3N8OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:550.64

    Ref: TM-T27904

  • BAY-899
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    BAY-899

    CAS:
    <p>BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.</p>
    Formula:C25H19F2N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:459.45

    Ref: TM-T10476

  • RGS10 modulator-1
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    RGS10 modulator-1

    CAS:
    <p>RGS10 modulator-1 (compound 15) is an effective regulator of RGS10. It significantly reverses IFNγ-induced expression of both RGS10 protein and mRNA, as well as COX-2 mRNA and iNOS expression triggered by IFNγ.</p>
    Formula:C16H15BrN2O3S2
    Color and Shape:Solid
    Molecular weight:427.336

    Ref: TM-T204267

  • PF-9404C
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    PF-9404C

    CAS:
    <p>PF-9404C: S-S diastereoisomer, beta-blocker with vasodilation, boosts cyclic GMP in rat aorta cells from 3 to 53 pmol/mg protein.</p>
    Formula:C16H25N3O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:403.38

    Ref: TM-T28391

  • MRT-92
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    MRT-92

    CAS:
    <p>MRT-92 is an antagonist of Smoothened (Smo) with anti-cancer activity, featuring a binding affinity (Ki) of 0.7 nM. It inhibits the Hedgehog signaling pathway by obstructing the overlapping binding sites within the transmembrane domain of the Smoothened receptor and suppresses the proliferation of cerebellar granule cells in rodents (IC50=0.4 nM). MRT-92 is utilized for research into cerebellar gliomas.</p>
    Formula:C33H34N4O5
    Color and Shape:Solid
    Molecular weight:566.65

    Ref: TM-T200033

  • 8 Hydroxy PIPAT oxalate
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    8 Hydroxy PIPAT oxalate

    CAS:
    8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.
    Formula:C18H24INO5
    Color and Shape:Solid
    Molecular weight:461.29

    Ref: TM-T201052

  • DM-4111
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    DM-4111

    CAS:
    <p>DM-4111, one of the primary monohydroxy metabolites of Tolvaptan, is an effective vasopressin V2 receptor (vasopressin V2 receptor) inhibitor. By inhibiting water reabsorption in renal tubules, it facilitates the excretion of electrolyte-free water. DM-4111 holds potential for research in cardiovascular diseases.</p>
    Formula:C26H25ClN2O4
    Color and Shape:Solid
    Molecular weight:464.94

    Ref: TM-T207517

  • AH22921
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    AH22921

    CAS:
    <p>AH22921 is an EP4 prostaglandin receptor antagonist with the ability to antagonize the activation of adenylyl cyclase by prostaglandins in CHO cells. It induces a rightward shift in the PGE? concentration-response curve in these cells, functioning as a non-competitive antagonist. AH22921 is selective for the EP4 receptor, inhibiting its activity in CHO cells without affecting the PGE? concentration-response curve in NPE cells that contain the EP2 receptor.</p>
    Formula:C29H35NO5
    Color and Shape:Solid
    Molecular weight:477.59

    Ref: TM-T200553

  • MSX-3
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    MSX-3

    CAS:
    <p>MSX-3 is an antagonist of the A2A adenosine receptor and a prodrug of MSX-2.</p>
    Formula:C21H23N4Na2O7P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:520.389

    Ref: TM-T25841

  • SB 224289
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    SB 224289

    CAS:
    <p>SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.</p>
    Formula:C32H32N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:520.62

    Ref: TM-T19690

  • CymitQuimica logo
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    SSTR5 antagonist 2 hydrochloride

    <p>SSTR5 antagonist 2 hydrochloride: potent, oral SSTR5 blocker with potential in type 2 diabetes research.</p>
    Formula:C32H36ClFN2O5
    Color and Shape:Solid
    Molecular weight:583.09

    Ref: TM-T64119

  • Ophiobolin C
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    Ophiobolin C

    CAS:
    <p>inhibitor of human CCR5 binding to HIV-1 gp120</p>
    Formula:C25H38O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:386.57

    Ref: TM-T23108

  • Disulergine
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    Disulergine

    CAS:
    <p>Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.</p>
    Formula:C17H24N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:348.46

    Ref: TM-T24003

  • Elsovaptan
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    Elsovaptan

    CAS:
    <p>Elsovaptan is an antagonist of the vasopressin receptor and is applicable for research in Alzheimer's disease.</p>
    Formula:C19H20ClN5O2
    Color and Shape:Solid
    Molecular weight:385.847

    Ref: TM-T206306

  • MK-8318
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    MK-8318

    CAS:
    <p>MK-8318 is an effective and selective antagonist of the CRTh2 receptor (Ki: 5.0 nM).</p>
    Formula:C27H26F4N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:534.5

    Ref: TM-T16097

  • L 668750
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    L 668750

    CAS:
    <p>L 668750 is an inhibitor of platelet-activating factor.</p>
    Formula:C25H34O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:510.6

    Ref: TM-T24321

  • Serlopitant
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    Serlopitant

    CAS:
    <p>Serlopitant is a selective antagonist of Neurokinin-1 (NK-1) receptor.</p>
    Formula:C29H28F7NO2
    Color and Shape:Solid
    Molecular weight:555.53

    Ref: TM-T4533

  • RS 12254
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    RS 12254

    CAS:
    <p>RS 12254 is a dopamine agonist and antihypertensive agent.</p>
    Formula:C28H40N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.63

    Ref: TM-T26131

  • LTD4 antagonist 1
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    LTD4 antagonist 1

    CAS:
    <p>LTD4 antagonist 1 is a potent and orally active antagonist of leukotriene D4 (LTD4; Ki: 0.57 nM).</p>
    Formula:C31H32F3N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:615.66

    Ref: TM-T10057

  • (S)-YNT-3708
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    (S)-YNT-3708

    CAS:
    <p>(S)-YNT-3708 is the S-isomer of YNT-3708, demonstrating relatively low activity against OX1R and OX2R receptors, with EC50 values of 3595 nM and 1661 nM, respectively.</p>
    Formula:C35H36N4O6S
    Color and Shape:Solid
    Molecular weight:640.749

    Ref: TM-T206866