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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5378 products of "GPCR/G-Protein"

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  • PF-9404C

    CAS:
    <p>PF-9404C: S-S diastereoisomer, beta-blocker with vasodilation, boosts cyclic GMP in rat aorta cells from 3 to 53 pmol/mg protein.</p>
    Formula:C16H25N3O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:403.38
  • WIN 66306

    CAS:
    <p>WIN 66306: Cyclic heptapeptide, blocks NK1/NK2 receptors, inhibits substance P-triggered contractions in guinea pig ileum.</p>
    Formula:C41H52N8O9
    Color and Shape:Solid
    Molecular weight:800.9
  • RGS10 modulator-1

    CAS:
    <p>RGS10 modulator-1 (compound 15) is an effective regulator of RGS10. It significantly reverses IFNγ-induced expression of both RGS10 protein and mRNA, as well as COX-2 mRNA and iNOS expression triggered by IFNγ.</p>
    Formula:C16H15BrN2O3S2
    Color and Shape:Solid
    Molecular weight:427.336
  • ONO-9780307

    CAS:
    <p>ONO-9780307 is a specific antagonist of LPA1 (lysophosphatidic acid receptor 1) (IC50: 2.7 nM).</p>
    Formula:C30H35NO7
    Color and Shape:Solid
    Molecular weight:521.6
  • Inupadenant HCl

    CAS:
    <p>Inupadenant (EOS-850) is a selective A2a receptor antagonist, targeting immunosuppression in tumors.</p>
    Formula:C25H27ClF2N8O4S2
    Color and Shape:Solid
    Molecular weight:641.11
  • U92016A hydrochloride

    CAS:
    <p>U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.</p>
    Formula:C19H26ClN3
    Color and Shape:Solid
    Molecular weight:331.89
  • CS-0777

    CAS:
    <p>CS-0777 is a potent, selective, and orally active S1P1 agonist (sphingosine 1-phosphate receptor modulator).</p>
    Formula:C21H31N2O5P
    Color and Shape:Solid
    Molecular weight:422.45
  • 2,3-dinor-11β-Prostaglandin F2α

    CAS:
    <p>2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where</p>
    Formula:C18H30O5
    Color and Shape:Solid
    Molecular weight:326.43
  • MRS2179 tetrasodium hydrate


    <p>MRS2179 blocks turkey P2Y1 receptor (Kb 102 nM, pA2 6.99), affects platelet aggregation, and has varying IC50s on P2 receptors.</p>
    Formula:C11H15N5Na4O10P2
    Color and Shape:Solid
    Molecular weight:576.21
  • Rivenprost

    CAS:
    <p>Rivenprost, selective EP4 agonist (Ki: 0.7 nM), promotes bone growth, osteoblast differentiation, and aids wound healing.</p>
    Formula:C24H34O6S
    Color and Shape:Solid
    Molecular weight:450.59
  • MRS2279

    CAS:
    <p>Selective, high affinity competitive antagonist of the P2Y1 receptor</p>
    Formula:C13H18ClN5O8P2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.71
  • Tofogliflozin

    CAS:
    Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).
    Formula:C22H26O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:386.44
  • SEP-363856 mesylate

    CAS:
    <p>SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.</p>
    Formula:C10H17NO4S2
    Color and Shape:Solid
    Molecular weight:279.38
  • Vofopitant

    CAS:
    <p>Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).</p>
    Formula:C21H23F3N6O
    Purity:97.86%
    Color and Shape:Solid
    Molecular weight:432.44
  • SB-224289 hydrochloride

    CAS:
    <p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>
    Formula:C32H33ClN4O3
    Purity:97.82% - 98.99%
    Color and Shape:Solid
    Molecular weight:557.08
  • Vofopitant dihydrochloride

    CAS:
    Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.
    Formula:C21H25Cl2F3N6O
    Purity:98.99%
    Color and Shape:Solid
    Molecular weight:505.36
  • SB-423562

    CAS:
    <p>SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.</p>
    Formula:C26H32N2O4
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:436.54
  • BQ-788

    CAS:
    <p>BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.</p>
    Formula:C34H51N5O7
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:641.8
  • LSN3318839

    CAS:
    <p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>
    Formula:C26H23Cl2N3O2
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:480.39
  • BMS-986141

    CAS:
    <p>BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614</p>
    Formula:C27H23N5O5S2
    Purity:98.43% - 99.26%
    Color and Shape:Solid
    Molecular weight:561.63