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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5378 products of "GPCR/G-Protein"

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  • Conessine hydrobromide

    CAS:
    <p>Conessine hydrobromide is a naturally occurring steroid alkaloid and has been used in traditional herbal medicine as a treatment for amoebic dysentery.</p>
    Formula:C24H41BrN2
    Color and Shape:Solid
    Molecular weight:437.51
  • α-CGRP (mouse, rat) TFA


    <p>α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions and</p>
    Formula:C162H262N50O52S2·C2HF3O2
    Purity:98%
    Color and Shape:Solid
  • 5-methoxy-α-Ethyltryptamine

    CAS:
    <p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>
    Formula:C13H18N2O
    Purity:98.25%
    Color and Shape:Solid
    Molecular weight:218.29
  • HTR2A antagonist 1


    <p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>
    Formula:C35H43Cl2F2N5O4
    Color and Shape:Solid
    Molecular weight:706.65
  • Tamuzimod

    CAS:
    <p>Tamuzimod, an effective immunomodulator, exhibits modulatory activity on S1P Receptors with EC50 values below 1 μM [1] [2].</p>
    Formula:C21H13Cl3F3N5O3
    Color and Shape:Solid
    Molecular weight:546.71
  • Sarafotoxin S6a

    CAS:
    Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.
    Formula:C105H156N28O34S5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2514.85
  • CGRP antagonist 6


    <p>CGRP Antagonist 6 (Compound 23) is a potent CGRP receptor antagonist (Ki: 0.84 nM). It is utilized in the study of migraines.</p>
    Color and Shape:Odour Solid
  • HTL22562

    CAS:
    <p>HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.</p>
    Formula:C40H49N11O5
    Color and Shape:Solid
    Molecular weight:763.904
  • Mosliciguat

    CAS:
    <p>Mosliciguat is a guanylate cyclase activator.</p>
    Formula:C41H36ClF3N2O5
    Color and Shape:Solid
    Molecular weight:729.19
  • RXFP3/4 agonist 1

    CAS:
    <p>RXFP3/4 agonist 1 is a relaxin family peptide 3/4 receptor (RXFP3/4) agonist(EC50s of 82/2 nM, respectivley).</p>
    Formula:C20H22ClN5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:383.88
  • Fasitibant chloride

    CAS:
    <p>Fasitibant chloride, a potent B2R blocker, alleviates pain and swelling in arthritis.</p>
    Formula:C36H49Cl3N6O6S
    Color and Shape:Solid
    Molecular weight:800.23
  • Tezusomant

    CAS:
    Tezusomant is an antagonist of the growth hormone receptor (growth hormone receptor). It is being investigated for potential use in conditions like acromegaly, which are caused by excessive secretion of growth hormone.
    Formula:C120H171N23O32S
    Color and Shape:Solid
    Molecular weight:2479.84
  • Sar-[D-Phe8]-des-Arg9-Bradykinin

    CAS:
    <p>Potent bradykinin B1 agonist, EC50 = 9.02 nM, enzyme resistant, induces hypotension and angiogenesis.</p>
    Formula:C47H66N12O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:975.11
  • Methdilazine

    CAS:
    <p>Methdilazine: oral antibiotic, histamine antagonist, fights mycobacterium (MIC 5-15 μg/mL) for infectious disease research.</p>
    Formula:C18H20N2S
    Color and Shape:Solid
    Molecular weight:296.43
  • Maceneolignan H

    CAS:
    <p>Maceneolignan H, a neolignane from Myristica fragrans, selectively blocks CCR3 (EC50=1.4μM) with allergy research potential.</p>
    Formula:C24H30O7
    Color and Shape:Solid
    Molecular weight:430.49
  • Zicronapine fumarate

    CAS:
    <p>Zicronapine fumarate, an antipsychotic, targets D1/D2 &amp; 5-HT2A receptors; may treat neuropsychiatric conditions.</p>
    Formula:C26H31ClN2O4
    Color and Shape:Solid
    Molecular weight:470.99
  • Ghrelin receptor full agonist-2

    CAS:
    <p>Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist.</p>
    Formula:C26H28ClN5O5S
    Color and Shape:Solid
    Molecular weight:558.05
  • Neuropeptide Y (human)

    CAS:
    <p>Neuropeptide Y (29-64), amide, human is a biologically active 36-amino acid peptide.</p>
    Formula:C189H285N55O57S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4271.68
  • Cloprostenol isopropyl ester

    CAS:
    <p>(+)-Chloprostol is a PGF2α agonist, mimics prostaglandin F2α, induces luteal dissolution in mares without side effects or stress.</p>
    Formula:C25H35ClO6
    Color and Shape:Solid
    Molecular weight:466.99
  • Seglitide

    CAS:
    <p>Peptide agonist targets sst2/sst5 receptors. IC50/Kd: sst1 &gt;1000, sst2 = 0.2-1.5, sst3 = 27-36, sst4 &gt;127, sst5 = 0.06-23 nM.</p>
    Formula:C44H56N8O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:808.98