GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,025 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
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CB1/2 agonist 1
Potent CB1/2 agonist 1; crosses blood-brain barrier; anti-inflammatory, analgesic; for multiple sclerosis research.Formula:C21H24BrFN2O2Color and Shape:SolidMolecular weight:435.33Apafant
CAS:Apafant (WEB 2086) is a PAF antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.Formula:C22H22ClN5O2SPurity:99.56%Color and Shape:SolidMolecular weight:455.96SSTR4 agonist 5
CAS:SSTR4 agonist5 (Compound 5) is an orally active agonist of the somatostatin receptor 4 (SSTR4) with an EC50 of 0.228 nM. It demonstrates good stability in human/rat liver microsomes and can inhibit mechanical hyperalgesia in rat models.Formula:C20H26N4OMolecular weight:338.447Histamine H3 antagonist-1
CAS:Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].
Formula:C24H28F3N3O2Color and Shape:SolidMolecular weight:447.49RF9 hydrochloride
RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).Formula:C26H39ClN6O3Color and Shape:SolidMolecular weight:519.08CS-0777
CAS:CS-0777 is a potent, selective, and orally active S1P1 agonist (sphingosine 1-phosphate receptor modulator).Formula:C21H31N2O5PColor and Shape:SolidMolecular weight:422.45Fasitibant
CAS:Fasitibant is a potent and selective nonpeptide kinin B2 receptor antagonist.Formula:C36H49Cl2N6O6SColor and Shape:SolidMolecular weight:764.78Leukotriene B4 dimethyl amide
CAS:LTB4 dimethyl amide: inhibits human neutrophil degranulation and rat lysozyme release; antagonizes LTB4 receptor on guinea pig lung membranes (Ki = 130 nM).Formula:C22H37NO3Color and Shape:SolidMolecular weight:363.53Dinoxyline
CAS:Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.Formula:C15H13NO3Color and Shape:SolidMolecular weight:255.27CCR4 antagonist 2
CAS:CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits TregFormula:C26H28Cl2N6OPurity:98%Color and Shape:SolidMolecular weight:511.45Rivenprost
CAS:Rivenprost, selective EP4 agonist (Ki: 0.7 nM), promotes bone growth, osteoblast differentiation, and aids wound healing.Formula:C24H34O6SColor and Shape:SolidMolecular weight:450.59U91356
CAS:U91356 is an agonist of the dopamine receptors.Formula:C13H17N3OPurity:98%Color and Shape:SolidMolecular weight:231.29SAR-114137
CAS:SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.Formula:C25H34N4O7SPurity:99.09% - 99.91%Color and Shape:SolidMolecular weight:534.63MRS2905 trisodium
CAS:MRS2905 (α,β-Methylene-2-thio-UDP) trisodium is a selective P2Y14R agonist with an EC50 of 0.92 nM. It shows no activity on UDP-activated P2Y6 receptors or other P2Y receptors.Formula:C10H13N2Na3O10P2SColor and Shape:SolidMolecular weight:484.199MK-8825
CAS:MK-8825 is a CGRP receptor antagonist.Formula:C31H30F2N6O3Color and Shape:SolidMolecular weight:572.61Tofogliflozin
CAS:Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).Formula:C22H26O6Purity:98%Color and Shape:SolidMolecular weight:386.44H3R antagonist 1
CAS:H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).Formula:C19H23N3O3Color and Shape:SolidMolecular weight:341.4TAK-024
CAS:TAK-024 is an inhibitor of platelet(IC50s of 31, 79 and 51 nM in human, monkey and guinea pig, respectively).Formula:C27H34N10O6Purity:98%Color and Shape:SolidMolecular weight:594.62TAAR1 agonist 3
CAS:TAAR1 agonist 3 is a potent agonist of Trace Amine-Associated Receptor 1 (TAAR1) with a pEC50 value of 7.6. Additionally, it acts as a full agonist at the α2AR with a pEC50 of 6. TAAR1 agonist 3 is utilized in the research of neuropsychiatric disorders.Formula:C10H13NOColor and Shape:SolidMolecular weight:163.22Aclidinium
CAS:Aclidinium, a dual-action compound, serves as a long-acting muscarinic antagonist and a β2-adrenoceptor (β2-AR) agonist, exhibiting bronchodilator properties. It effectively reduces lung hyperinflation, enhances lung function, and prolongs exercise endurance time. This compound is commonly utilized in studies focusing on chronic obstructive pulmonary disease (COPD).Formula:C26H30NO4S2Color and Shape:SolidMolecular weight:484.65
