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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5985 products of "GPCR/G-Protein"

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  • Nolpitantium besilate

    CAS:
    Nolpitantium besilate is a neurokinin-1 receptor antagonist.
    Formula:C43H50Cl2N2O5S
    Color and Shape:Solid
    Molecular weight:777.84

    Ref: TM-T70455

    25mg
    2,718.00€
    50mg
    3,582.00€
    100mg
    4,950.00€
  • SCH-900822

    CAS:
    SCH-900822 is a potent and selective glucagon receptor antagonist.
    Formula:C34H43Cl2N7O2
    Color and Shape:Solid
    Molecular weight:652.66

    Ref: TM-T71201

    25mg
    2,313.00€
    50mg
    3,042.00€
    100mg
    4,140.00€
  • DA-302168S

    CAS:
    DA-302168S is an orally active, selective GLP-1R agonist with an EC50 value of 1.32 nM. It promotes insulin secretion and has a hypoglycemic effect. Additionally, DA-302168S reduces food intake. It primarily activates GLP-1R in humans and monkeys, with minimal effect on GLP-1R in rats, mice, and dogs. DA-302168S can be used for research in type 2 diabetes and obesity.
    Formula:C33H24ClF2N3O5
    Color and Shape:Solid
    Molecular weight:616.011

    Ref: TM-T206917

    10mg
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    50mg
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  • Tofogliflozin

    CAS:
    Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).
    Formula:C22H26O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:386.44

    Ref: TM-T13179

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • (S)-Butaprost free acid

    CAS:
    (S)-Butaprost (free acid) is a potent and highly selective EP2 receptor agonist[1].
    Formula:C23H38O5
    Color and Shape:Solid
    Molecular weight:394.54

    Ref: TM-T41369

    500µg
    344.00€
    1mg
    645.00€
    5mg
    2,583.00€
    10mg
    4,708.00€
  • Terguride

    CAS:
    Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.
    Formula:C20H28N4O
    Color and Shape:Solid
    Molecular weight:340.46

    Ref: TM-T71847

    25mg
    5,284.00€
    50mg
    7,002.00€
    100mg
    10,080.00€
  • AMG-369

    CAS:
    AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.
    Formula:C26H22FN3O2S
    Purity:98.04% - 98.92%
    Color and Shape:Solid
    Molecular weight:459.54

    Ref: TM-T29971

    1mg
    393.00€
    5mg
    930.00€
    10mg
    1,254.00€
    25mg
    1,863.00€
  • Disulergine

    CAS:
    Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.
    Formula:C17H24N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:348.46

    Ref: TM-T24003

    25mg
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    50mg
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    100mg
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  • PD-147693

    CAS:
    PD-147693 (compound II) is an active metabolite of the presynaptic dopamine autoreceptor agonist CI-1007, and it exhibits antipsychotic activity similar to CI-1007.
    Formula:C24H27NO
    Color and Shape:Solid
    Molecular weight:345.477

    Ref: TM-T204694

    10mg
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    50mg
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  • OP-2507

    CAS:
    OP-2507, a prostacyclin agonist, is used potentially for the treatment of hepatic insufficiency and hypertension.
    Formula:C25H41NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:419.6

    Ref: TM-T28254

    25mg
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    50mg
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    100mg
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  • 5-HT7R antagonist 1


    5-HT7R antagonist 1 is a G protein-biased antagonist with Ki of 6.5 nM for 5-HT 7R.
    Formula:C14H18Cl2N4
    Color and Shape:Solid
    Molecular weight:313.23

    Ref: TM-T60790

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Vibegron

    CAS:
    Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).
    Formula:C26H28N4O3
    Color and Shape:Solid
    Molecular weight:444.53

    Ref: TM-T35052

    25mg
    1,340.00€
    50mg
    1,890.00€
    100mg
    2,582.00€
  • SPL-IN-1

    CAS:
    SPL-IN-1 (compound C17) acts as a dual species inhibitor of sphingosine-1-phosphate lyase [1].
    Formula:C31H42N2O6S2
    Color and Shape:Solid
    Molecular weight:602.8

    Ref: TM-T87436

    10mg
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    50mg
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  • PF-07054894

    CAS:
    PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.
    Formula:C24H30N6O4
    Color and Shape:Solid
    Molecular weight:466.53

    Ref: TM-T73005

    25mg
    2,853.00€
    50mg
    3,763.00€
    100mg
    5,220.00€
  • SS-RJW100


    SS-RJW100 is an enantiomer of RJW100 targeting LRH-1, SF-1, enhances Tif2 interaction, and disrupts LRH-1 networks with lowered stability.
    Formula:C28H34O
    Color and Shape:Solid
    Molecular weight:386.57

    Ref: TM-T61723

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Udifitimod

    CAS:
    Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.
    Formula:C25H33NO2
    Color and Shape:Solid
    Molecular weight:379.54

    Ref: TM-T73092

    25mg
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    50mg
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    100mg
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  • Tezosentan

    CAS:
    Tezosentan is an antagonist of the endothelin receptor (pA2s: 9.5, 7.7 for ETA and ETB receptors, respectively).
    Formula:C27H27N9O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:605.63

    Ref: TM-T17064

    25mg
    2,025.00€
    50mg
    2,737.00€
    100mg
    3,565.00€
  • CI-988

    CAS:
    CCK2 (CCK-B) receptor antagonist
    Formula:C35H42N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:614.73

    Ref: TM-T22666

    10mg
    1,288.00€
  • AFP-07 free acid

    CAS:
    AFP 07 free acid is a 7,7-difluoroprostacyclin derivative. It also acts as a selective and highly potent agonist for the IP receptor.
    Formula:C22H30F2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:412.47

    Ref: TM-T23657L

    500µg
    384.00€
    1mg
    743.00€
    5mg
    3,105.00€
  • NPRA agonist-11

    CAS:
    NPRA agonist-11 (Example 161) is an NPRA (NPR1) agonist with AC50 values of 1.681 μM and 0.989 μM for human and monkey, respectively. It is applicable in research on cardiovascular and other diseases.
    Formula:C37H52FN7O2
    Color and Shape:Solid
    Molecular weight:645.85

    Ref: TM-T211535

    10mg
    To inquire
    50mg
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