GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 19 more subcategories

Found 5838 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

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SGLT1/2-IN-2
CAS:
- 2387812-73-7
SGLT1/2-IN-2 is a chemical compound with robust dual inhibitory properties, exhibiting potent activities against SGLT1 (IC50 = 96 nM) and SGLT2 (IC50 = 1.3 nM).
Formula:C₂₃H₂₆F₂O₇
Color and Shape:Solid
Molecular weight:452.451
Ref: TM-T39966
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15-keto Latanoprost
CAS:
- 135646-98-9
Latanoprost, a PG analog for ocular pressure, metabolizes into 15-keto latanoprost, a less potent variant reducing intraocular pressure and pupil size.
Formula:C₂₆H₃₈O₅
Color and Shape:Solid
Molecular weight:430.58
Ref: TM-T37932
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α-Helical CRF(9-41)
CAS:
- 90880-23-2
Corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).
Formula:C₁₆₆H₂₇₄N₄₆O₅₃S₂
Purity:98%
Color and Shape:Solid
Molecular weight:3827
Ref: TM-TP2048
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5-HT2C agonist-4
CAS:
- 2730085-33-1
Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.
Formula:C₂₄H₂₅N₅O
Color and Shape:Solid
Molecular weight:399.49
Ref: TM-T203570
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ALEPH hydrochloride
CAS:
- 61638-08-2
ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.
Formula:C₁₂H₂₀ClNO₂S
Color and Shape:Solid
Molecular weight:277.81
Ref: TM-T203157
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Galanin (1-16), mouse, porcine, rat TFA
Galanin (1-16) agonizes hippocampal receptors; Kd 3 nM. Active on locus coeruleus neurons in mice, pigs, rats.
Formula:C₈₀H₁₁₇F₃N₂₀O₂₃
Purity:98%
Color and Shape:Solid
Molecular weight:1783.9
Ref: TM-TP1317
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IRL-1038 acetate
IRL-1038 acetate is a potent ETB endothelin receptor antagonist.
Formula:C₇₀H₉₆N₁₄O₁₇S₂
Purity:97.51%
Color and Shape:Soild
Molecular weight:1469.73
Ref: TM-TP2262L
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Ki16198
CAS:
- 355025-13-7
Ki16198, a methyl ester derivative of Ki16425, blocks LPA1/3, weak on LPA2; inactive on LPA4/5/6. Ki values: 0.34 μM (LPA1), 0.93 μM (LPA3).
Formula:C₂₄H₂₅ClN₂O₅S
Purity:98.09%
Color and Shape:Solid
Molecular weight:488.98
Ref: TM-T6347
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PHM-27 (human)
CAS:
- 87403-73-4
Human-derived peptide, VIP/PHM 27 analog, boosts insulin by targeting calcitonin receptor with an EC50 of 11 nM.
Formula:C₁₃₅H₂₁₄N₃₄O₄₀S
Purity:98%
Color and Shape:Solid
Molecular weight:2985.44
Ref: TM-TP1954
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tetranor-PGDM
CAS:
- 70803-91-7
PGD2, made by H-PGDS in mast cells and lipocalin-PGD-synthase in the brain, aids sleep, cools the body, and inhibits platelet aggregation.
Formula:C₁₆H₂₄O₇
Color and Shape:Solid
Molecular weight:328.361
Ref: TM-T38306
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(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
CAS:
- 1926163-39-4
Analog of LHRH, stimulates LH and FSH release, controls reproduction.
Formula:C₅₉H₈₄N₁₈O₁₄
Color and Shape:Solid
Molecular weight:1269.41
Ref: TM-T76616
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Neuropeptide Y5 receptor ligand-1
CAS:
- 322723-35-3
Neuropeptide Y5 receptor ligand-1 (Compound 54), a carbazole derivative, acts as a powerful antagonist to the neuropeptide Y5 (NPY-5) receptor [1].
Formula:C₁₉H₁₇N₃O₂
Color and Shape:Solid
Molecular weight:319.36
Ref: TM-T74654
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[bAla8]-Neurokinin A(4-10)
CAS:
- 122063-01-8
[bAla8]-Neurokinin A(4-10) is a neurokinin 2 (NK2) receptor agonist.
Formula:C₃₅H₅₆N₈O₁₀S
Purity:98%
Color and Shape:Solid
Molecular weight:780.94
Ref: TM-TP1100
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d[Leu4,Lys8]-VP
CAS:
- 42061-33-6
Vasopressin V1B agonist; Ki: 0.16nM V1B, 64nM oxytocin; weak antidiuretic/vasopressor; minimal oxytocic action.
Formula:C₄₇H₆₇N₁₁O₁₁S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1026.2
Ref: TM-TP1927
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Amylin (IAPP), feline
Amylin (IAPP), feline is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas.
Formula:C₁₆₅H₂₇₀N₅₂O₅₄S₂
Purity:98%
Color and Shape:Solid
Molecular weight:3910.45
Ref: TM-TP1519
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A 31472
CAS:
- 69319-52-4
A 31472 is a tetracyclic spiro amine that has affinity for dopamine D-2 receptors.
Formula:C₂₂H₂₂ClN
Color and Shape:Solid
Molecular weight:335.87
Ref: TM-T26415
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Sarafotoxin S6a
CAS:
- 126738-34-9
Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.
Formula:C₁₀₅H₁₅₆N₂₈O₃₄S₅
Purity:98%
Color and Shape:Solid
Molecular weight:2514.85
Ref: TM-TP2119
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CRL-42872 free base
CAS:
- 256344-23-7
CRL-42872 free base is a bioactive chemical.
Formula:C₂₂H₂₆N₆O₆S
Color and Shape:Solid
Molecular weight:502.54
Ref: TM-T31098
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Blue FPG-A trisodium
CAS:
- 78617-94-4
Blue FPG-A trisodium is a P2X1 & P2Y1 receptor antagonist, IC50: 35.5 μM & 2.6 μM, related to RB2.
Formula:C₂₉H₁₇ClN₇Na₃O₁₁S₃
Color and Shape:Solid
Molecular weight:840.1
Ref: TM-T75347
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SRA880 malonate
CAS:
- 573984-99-3
SRA880: non-peptide sst(1) antagonist, low affinity for other sst receptors, binds dopamine D4, boosts SRIF, antidepressant-like effects.
Formula:C₂₉H₃₆N₄O₈
Purity:98%
Color and Shape:Solid
Molecular weight:568.62
Ref: TM-T26225